LOCUS AY123250 4060 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform G (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY123250
VERSION AY123250.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4060)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 4060)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
REFERENCE 3 (bases 1 to 4060)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
FEATURES Location/Qualifiers
source 1..4060
/db_xref="H-InvDB:HIT000084570"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/tissue_type="testis"
gene 1..4060
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..133
/gene="RTN4"
/gene_synonym="NOGO"
CDS 134..3094
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-G; alternatively spliced"
/codon_start=1
/product="RTN4 isoform G"
/protein_id="AAM64254.1"
/translation="MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHE
YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSP
KAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAK
DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC
FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPL
LGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCP
SFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPD
FSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLT
ETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPL
QMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLARE
YTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATS
KVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTS
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK
FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMA
KIQAKIPGLKRKAE"
3'UTR 3095..4060
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 1326 a 739 c 823 g 1172 t
ORIGIN
1 aatattgcct gttctacaga gttccctaat tccatattga tgatacctat tgggaaactt
61 tagttttttt aatgagaccc tttttgctct tcctgctgca tctgagcctg tgatacgctc
121 ctctgcagaa aatatggact tgaaggagca gccaggtaac actatttcgg ctggtcaaga
181 ggatttccca tctgtcctgc ttgaaactgc tgcttctctt ccttctctgt ctcctctctc
241 agccgcttct ttcaaagaac atgaatacct tggtaatttg tcaacagtat tacccactga
301 aggaacactt caagaaaatg tcagtgaagc ttctaaagag gtctcagaga aggcaaaaac
361 tctactcata gatagagatt taacagagtt ttcagaatta gaatactcag aaatgggatc
421 atcgttcagt gtctctccaa aagcagaatc tgccgtaata gtagcaaatc ctagggaaga
481 aataatcgtg aaaaataaag atgaagaaga gaagttagtt agtaataaca tccttcataa
541 tcaacaagag ttacctacag ctcttactaa attggttaaa gaggatgaag ttgtgtcttc
601 agaaaaagca aaagacagtt ttaatgaaaa gagagttgca gtggaagctc ctatgaggga
661 ggaatatgca gacttcaaac catttgagcg agtatgggaa gtgaaagata gtaaggaaga
721 tagtgatatg ttggctgctg gaggtaaaat cgagagcaac ttggaaagta aagtggataa
781 aaaatgtttt gcagatagcc ttgagcaaac taatcacgaa aaagatagtg agagtagtaa
841 tgatgatact tctttcccca gtacgccaga aggtataaag gatcgttcag gagcatatat
901 cacatgtgct ccctttaacc cagcagcaac tgagagcatt gcaacaaaca tttttccttt
961 gttaggagat cctacttcag aaaataagac cgatgaaaaa aaaatagaag aaaagaaggc
1021 ccaaatagta acagagaaga atactagcac caaaacatca aacccttttc ttgtagcagc
1081 acaggattct gagacagatt atgtcacaac agataattta acaaaggtga ctgaggaagt
1141 cgtggcaaac atgcctgaag gcctgactcc agatttagta caggaagcat gtgaaagtga
1201 attgaatgaa gttactggta caaagattgc ttatgaaaca aaaatggact tggttcaaac
1261 atcagaagtt atgcaagagt cactctatcc tgcagcacag ctttgcccat catttgaaga
1321 gtcagaagct actccttcac cagttttgcc tgacattgtt atggaagcac cattgaattc
1381 tgcagttcct agtgctggtg cttccgtgat acagcccagc tcatcaccat tagaagcttc
1441 ttcagttaat tatgaaagca taaaacatga gcctgaaaac cccccaccat atgaagaggc
1501 catgagtgta tcactaaaaa aagtatcagg aataaaggaa gaaattaaag agcctgaaaa
1561 tattaatgca gctcttcaag aaacagaagc tccttatata tctattgcat gtgatttaat
1621 taaagaaaca aagctttctg ctgaaccagc tccggatttc tctgattatt cagaaatggc
1681 aaaagttgaa cagccagtgc ctgatcattc tgagctagtt gaagattcct cacctgattc
1741 tgaaccagtt gacttattta gtgatgattc aatacctgac gttccacaaa aacaagatga
1801 aactgtgatg cttgtgaaag aaagtctcac tgagacttca tttgagtcaa tgatagaata
1861 tgaaaataag gaaaaactca gtgctttgcc acctgaggga ggaaagccat atttggaatc
1921 ttttaagctc agtttagata acacaaaaga taccctgtta cctgatgaag tttcaacatt
1981 gagcaaaaag gagaaaattc ctttgcagat ggaggagctc agtactgcag tttattcaaa
2041 tgatgactta tttatttcta aggaagcaca gataagagaa actgaaacgt tttcagattc
2101 atctccaatt gaaattatag atgagttccc tacattgatc agttctaaaa ctgattcatt
2161 ttctaaatta gccagggaat atactgacct agaagtatcc cacaaaagtg aaattgctaa
2221 tgccccggat ggagctgggt cattgccttg cacagaattg ccccatgacc tttctttgaa
2281 gaacatacaa cccaaagttg aagagaaaat cagtttctca gatgactttt ctaaaaatgg
2341 gtctgctaca tcaaaggtgc tcttattgcc tccagatgtt tctgctttgg ccactcaagc
2401 agagatagag agcatagtta aacccaaagt tcttgtgaaa gaagctgaga aaaaacttcc
2461 ttccgataca gaaaaagagg acagatcacc atctgctata ttttcagcag agctgagtaa
2521 aacttcagtt gttgacctcc tgtactggag agacattaag aagactggag tggtgtttgg
2581 tgccagccta ttcctgctgc tttcattgac agtattcagc attgtgagcg taacagccta
2641 cattgccttg gccctgctct ctgtgaccat cagctttagg atatacaagg gtgtgatcca
2701 agctatccag aaatcagatg aaggccaccc attcagggca tatctggaat ctgaagttgc
2761 tatatctgag gagttggttc agaagtacag taattctgct cttggtcatg tgaactgcac
2821 gataaaggaa ctcaggcgcc tcttcttagt tgatgattta gttgattctc tgaagtttgc
2881 agtgttgatg tgggtattta cctatgttgg tgccttgttt aatggtctga cactactgat
2941 tttggctctc atttcactct tcagtgttcc tgttatttat gaacggcatc aggcacagat
3001 agatcattat ctaggacttg caaataagaa tgttaaagat gctatggcta aaatccaagc
3061 aaaaatccct ggattgaagc gcaaagctga atgaaaacgc ccaaaataat tagtaggagt
3121 tcatctttaa aggggatatt catttgatta tacgggggag ggtcagggaa gaacgaacct
3181 tgacgttgca gtgcagtttc acagatcgtt gttagatctt tatttttagc catgcactgt
3241 tgtgaggaaa aattacctgt cttgactgcc atgtgttcat catcttaagt attgtaagct
3301 gctatgtatg gatttaaacc gtaatcatat ctttttccta tctgaggcac tggtggaata
3361 aaaaacctgt atattttact ttgttgcaga tagtcttgcc gcatcttggc aagttgcaga
3421 gatggtggag ctagaaaaaa aaaaaaaaaa gcccttttca gtttgtgcac tgtgtatggt
3481 ccgtgtagat tgatgcagat tttctgaaat gaaatgtttg tttagacgag atcataccgg
3541 taaagcagga atgacaaagc ttgcttttct ggtatgttct aggtgtattg tgacttttac
3601 tgttatatta attgccaata taagtaaata tagattatat atgtatagtg tttcacaaag
3661 cttagacctt taccttccag ccaccccaca gtgcttgata tttcagagtc agtcattggt
3721 tatacatgtg tagttccaaa gcacataagc tagaagaaga aatatttcta ggagcactac
3781 catctgtttt caacatgaaa tgccacacac atagaactcc aacaacatca atttcattgc
3841 acagactgac tgtagttaat tttgtcacag aatctatgga ctgaatctaa tgcttccaaa
3901 aatgttgttt gtttgcaaat atcaaacatt gttatgcaag aaattattaa ttacaaaatg
3961 aagatttata ccattgtggt ttaagctgta ctgaactaaa tctgtggaat gcattgtgaa
4021 ctgtaaaagc aaagtatcaa taaagcttat agacttaaaa
//