LOCUS AY123249 4070 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform F (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY123249
VERSION AY123249.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4070)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 4070)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
REFERENCE 3 (bases 1 to 4070)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
FEATURES Location/Qualifiers
source 1..4070
/db_xref="H-InvDB:HIT000084569"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/tissue_type="testis"
gene 1..4070
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..143
/gene="RTN4"
/gene_synonym="NOGO"
CDS 144..3104
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-F; alternatively spliced"
/codon_start=1
/product="RTN4 isoform F"
/protein_id="AAM64253.1"
/translation="MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHE
YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSP
KAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAK
DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC
FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPL
LGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCP
SFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPD
FSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLT
ETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPL
QMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLARE
YTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATS
KVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTS
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK
FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMA
KIQAKIPGLKRKAE"
3'UTR 3105..4070
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 1324 a 746 c 836 g 1164 t
ORIGIN
1 gtggctccat aaggttgtaa tggagctgaa aaattcctgc cgcctagcga cgtcttgatc
61 ttgaccctgt gtaggcctag gatgagaccc tttttgctct tcctgctgca tctgagcctg
121 tgatacgctc ctctgcagaa aatatggact tgaaggagca gccaggtaac actatttcgg
181 ctggtcaaga ggatttccca tctgtcctgc ttgaaactgc tgcttctctt ccttctctgt
241 ctcctctctc agccgcttct ttcaaagaac atgaatacct tggtaatttg tcaacagtat
301 tacccactga aggaacactt caagaaaatg tcagtgaagc ttctaaagag gtctcagaga
361 aggcaaaaac tctactcata gatagagatt taacagagtt ttcagaatta gaatactcag
421 aaatgggatc atcgttcagt gtctctccaa aagcagaatc tgccgtaata gtagcaaatc
481 ctagggaaga aataatcgtg aaaaataaag atgaagaaga gaagttagtt agtaataaca
541 tccttcataa tcaacaagag ttacctacag ctcttactaa attggttaaa gaggatgaag
601 ttgtgtcttc agaaaaagca aaagacagtt ttaatgaaaa gagagttgca gtggaagctc
661 ctatgaggga ggaatatgca gacttcaaac catttgagcg agtatgggaa gtgaaagata
721 gtaaggaaga tagtgatatg ttggctgctg gaggtaaaat cgagagcaac ttggaaagta
781 aagtggataa aaaatgtttt gcagatagcc ttgagcaaac taatcacgaa aaagatagtg
841 agagtagtaa tgatgatact tctttcccca gtacgccaga aggtataaag gatcgttcag
901 gagcatatat cacatgtgct ccctttaacc cagcagcaac tgagagcatt gcaacaaaca
961 tttttccttt gttaggagat cctacttcag aaaataagac cgatgaaaaa aaaatagaag
1021 aaaagaaggc ccaaatagta acagagaaga atactagcac caaaacatca aacccttttc
1081 ttgtagcagc acaggattct gagacagatt atgtcacaac agataattta acaaaggtga
1141 ctgaggaagt cgtggcaaac atgcctgaag gcctgactcc agatttagta caggaagcat
1201 gtgaaagtga attgaatgaa gttactggta caaagattgc ttatgaaaca aaaatggact
1261 tggttcaaac atcagaagtt atgcaagagt cactctatcc tgcagcacag ctttgcccat
1321 catttgaaga gtcagaagct actccttcac cagttttgcc tgacattgtt atggaagcac
1381 cattgaattc tgcagttcct agtgctggtg cttccgtgat acagcccagc tcatcaccat
1441 tagaagcttc ttcagttaat tatgaaagca taaaacatga gcctgaaaac cccccaccat
1501 atgaagaggc catgagtgta tcactaaaaa aagtatcagg aataaaggaa gaaattaaag
1561 agcctgaaaa tattaatgca gctcttcaag aaacagaagc tccttatata tctattgcat
1621 gtgatttaat taaagaaaca aagctttctg ctgaaccagc tccggatttc tctgattatt
1681 cagaaatggc aaaagttgaa cagccagtgc ctgatcattc tgagctagtt gaagattcct
1741 cacctgattc tgaaccagtt gacttattta gtgatgattc aatacctgac gttccacaaa
1801 aacaagatga aactgtgatg cttgtgaaag aaagtctcac tgagacttca tttgagtcaa
1861 tgatagaata tgaaaataag gaaaaactca gtgctttgcc acctgaggga ggaaagccat
1921 atttggaatc ttttaagctc agtttagata acacaaaaga taccctgtta cctgatgaag
1981 tttcaacatt gagcaaaaag gagaaaattc ctttgcagat ggaggagctc agtactgcag
2041 tttattcaaa tgatgactta tttatttcta aggaagcaca gataagagaa actgaaacgt
2101 tttcagattc atctccaatt gaaattatag atgagttccc tacattgatc agttctaaaa
2161 ctgattcatt ttctaaatta gccagggaat atactgacct agaagtatcc cacaaaagtg
2221 aaattgctaa tgccccggat ggagctgggt cattgccttg cacagaattg ccccatgacc
2281 tttctttgaa gaacatacaa cccaaagttg aagagaaaat cagtttctca gatgactttt
2341 ctaaaaatgg gtctgctaca tcaaaggtgc tcttattgcc tccagatgtt tctgctttgg
2401 ccactcaagc agagatagag agcatagtta aacccaaagt tcttgtgaaa gaagctgaga
2461 aaaaacttcc ttccgataca gaaaaagagg acagatcacc atctgctata ttttcagcag
2521 agctgagtaa aacttcagtt gttgacctcc tgtactggag agacattaag aagactggag
2581 tggtgtttgg tgccagccta ttcctgctgc tttcattgac agtattcagc attgtgagcg
2641 taacagccta cattgccttg gccctgctct ctgtgaccat cagctttagg atatacaagg
2701 gtgtgatcca agctatccag aaatcagatg aaggccaccc attcagggca tatctggaat
2761 ctgaagttgc tatatctgag gagttggttc agaagtacag taattctgct cttggtcatg
2821 tgaactgcac gataaaggaa ctcaggcgcc tcttcttagt tgatgattta gttgattctc
2881 tgaagtttgc agtgttgatg tgggtattta cctatgttgg tgccttgttt aatggtctga
2941 cactactgat tttggctctc atttcactct tcagtgttcc tgttatttat gaacggcatc
3001 aggcacagat agatcattat ctaggacttg caaataagaa tgttaaagat gctatggcta
3061 aaatccaagc aaaaatccct ggattgaagc gcaaagctga atgaaaacgc ccaaaataat
3121 tagtaggagt tcatctttaa aggggatatt catttgatta tacgggggag ggtcagggaa
3181 gaacgaacct tgacgttgca gtgcagtttc acagatcgtt gttagatctt tatttttagc
3241 catgcactgt tgtgaggaaa aattacctgt cttgactgcc atgtgttcat catcttaagt
3301 attgtaagct gctatgtatg gatttaaacc gtaatcatat ctttttccta tctgaggcac
3361 tggtggaata aaaaacctgt atattttact ttgttgcaga tagtcttgcc gcatcttggc
3421 aagttgcaga gatggtggag ctagaaaaaa aaaaaaaaaa gcccttttca gtttgtgcac
3481 tgtgtatggt ccgtgtagat tgatgcagat tttctgaaat gaaatgtttg tttagacgag
3541 atcataccgg taaagcagga atgacaaagc ttgcttttct ggtatgttct aggtgtattg
3601 tgacttttac tgttatatta attgccaata taagtaaata tagattatat atgtatagtg
3661 tttcacaaag cttagacctt taccttccag ccaccccaca gtgcttgata tttcagagtc
3721 agtcattggt tatacatgtg tagttccaaa gcacataagc tagaagaaga aatatttcta
3781 ggagcactac catctgtttt caacatgaaa tgccacacac atagaactcc aacaacatca
3841 atttcattgc acagactgac tgtagttaat tttgtcacag aatctatgga ctgaatctaa
3901 tgcttccaaa aatgttgttt gtttgcaaat atcaaacatt gttatgcaag aaattattaa
3961 ttacaaaatg aagatttata ccattgtggt ttaagctgta ctgaactaaa tctgtggaat
4021 gcattgtgaa ctgtaaaagc aaagtatcaa taaagcttat agacttaaaa
//