LOCUS AY123248 4109 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform E (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY123248
VERSION AY123248.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4109)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 4109)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
REFERENCE 3 (bases 1 to 4109)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
FEATURES Location/Qualifiers
source 1..4109
/db_xref="H-InvDB:HIT000084568"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/tissue_type="testis"
gene 1..4109
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..182
/gene="RTN4"
/gene_synonym="NOGO"
CDS 183..3143
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-E; alternatively spliced"
/codon_start=1
/product="RTN4 isoform E"
/protein_id="AAM64252.1"
/translation="MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHE
YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSP
KAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAK
DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC
FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPL
LGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCP
SFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPD
FSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLT
ETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPL
QMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLARE
YTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATS
KVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTS
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK
FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMA
KIQAKIPGLKRKAE"
3'UTR 3144..4109
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 1333 a 754 c 858 g 1164 t
ORIGIN
1 ctcctcctgt gctcgtgggg agctggccga gtggaaaacg tccacattga cccaaccgca
61 gtgaagggag agcgcctcca gtggtgtggt gcgtggagaa atgggaagga gagagttctg
121 atgagaccct ttttgctctt cctgctgcat ctgagcctgt gatacgctcc tctgcagaaa
181 atatggactt gaaggagcag ccaggtaaca ctatttcggc tggtcaagag gatttcccat
241 ctgtcctgct tgaaactgct gcttctcttc cttctctgtc tcctctctca gccgcttctt
301 tcaaagaaca tgaatacctt ggtaatttgt caacagtatt acccactgaa ggaacacttc
361 aagaaaatgt cagtgaagct tctaaagagg tctcagagaa ggcaaaaact ctactcatag
421 atagagattt aacagagttt tcagaattag aatactcaga aatgggatca tcgttcagtg
481 tctctccaaa agcagaatct gccgtaatag tagcaaatcc tagggaagaa ataatcgtga
541 aaaataaaga tgaagaagag aagttagtta gtaataacat ccttcataat caacaagagt
601 tacctacagc tcttactaaa ttggttaaag aggatgaagt tgtgtcttca gaaaaagcaa
661 aagacagttt taatgaaaag agagttgcag tggaagctcc tatgagggag gaatatgcag
721 acttcaaacc atttgagcga gtatgggaag tgaaagatag taaggaagat agtgatatgt
781 tggctgctgg aggtaaaatc gagagcaact tggaaagtaa agtggataaa aaatgttttg
841 cagatagcct tgagcaaact aatcacgaaa aagatagtga gagtagtaat gatgatactt
901 ctttccccag tacgccagaa ggtataaagg atcgttcagg agcatatatc acatgtgctc
961 cctttaaccc agcagcaact gagagcattg caacaaacat ttttcctttg ttaggagatc
1021 ctacttcaga aaataagacc gatgaaaaaa aaatagaaga aaagaaggcc caaatagtaa
1081 cagagaagaa tactagcacc aaaacatcaa acccttttct tgtagcagca caggattctg
1141 agacagatta tgtcacaaca gataatttaa caaaggtgac tgaggaagtc gtggcaaaca
1201 tgcctgaagg cctgactcca gatttagtac aggaagcatg tgaaagtgaa ttgaatgaag
1261 ttactggtac aaagattgct tatgaaacaa aaatggactt ggttcaaaca tcagaagtta
1321 tgcaagagtc actctatcct gcagcacagc tttgcccatc atttgaagag tcagaagcta
1381 ctccttcacc agttttgcct gacattgtta tggaagcacc attgaattct gcagttccta
1441 gtgctggtgc ttccgtgata cagcccagct catcaccatt agaagcttct tcagttaatt
1501 atgaaagcat aaaacatgag cctgaaaacc ccccaccata tgaagaggcc atgagtgtat
1561 cactaaaaaa agtatcagga ataaaggaag aaattaaaga gcctgaaaat attaatgcag
1621 ctcttcaaga aacagaagct ccttatatat ctattgcatg tgatttaatt aaagaaacaa
1681 agctttctgc tgaaccagct ccggatttct ctgattattc agaaatggca aaagttgaac
1741 agccagtgcc tgatcattct gagctagttg aagattcctc acctgattct gaaccagttg
1801 acttatttag tgatgattca atacctgacg ttccacaaaa acaagatgaa actgtgatgc
1861 ttgtgaaaga aagtctcact gagacttcat ttgagtcaat gatagaatat gaaaataagg
1921 aaaaactcag tgctttgcca cctgagggag gaaagccata tttggaatct tttaagctca
1981 gtttagataa cacaaaagat accctgttac ctgatgaagt ttcaacattg agcaaaaagg
2041 agaaaattcc tttgcagatg gaggagctca gtactgcagt ttattcaaat gatgacttat
2101 ttatttctaa ggaagcacag ataagagaaa ctgaaacgtt ttcagattca tctccaattg
2161 aaattataga tgagttccct acattgatca gttctaaaac tgattcattt tctaaattag
2221 ccagggaata tactgaccta gaagtatccc acaaaagtga aattgctaat gccccggatg
2281 gagctgggtc attgccttgc acagaattgc cccatgacct ttctttgaag aacatacaac
2341 ccaaagttga agagaaaatc agtttctcag atgacttttc taaaaatggg tctgctacat
2401 caaaggtgct cttattgcct ccagatgttt ctgctttggc cactcaagca gagatagaga
2461 gcatagttaa acccaaagtt cttgtgaaag aagctgagaa aaaacttcct tccgatacag
2521 aaaaagagga cagatcacca tctgctatat tttcagcaga gctgagtaaa acttcagttg
2581 ttgacctcct gtactggaga gacattaaga agactggagt ggtgtttggt gccagcctat
2641 tcctgctgct ttcattgaca gtattcagca ttgtgagcgt aacagcctac attgccttgg
2701 ccctgctctc tgtgaccatc agctttagga tatacaaggg tgtgatccaa gctatccaga
2761 aatcagatga aggccaccca ttcagggcat atctggaatc tgaagttgct atatctgagg
2821 agttggttca gaagtacagt aattctgctc ttggtcatgt gaactgcacg ataaaggaac
2881 tcaggcgcct cttcttagtt gatgatttag ttgattctct gaagtttgca gtgttgatgt
2941 gggtatttac ctatgttggt gccttgttta atggtctgac actactgatt ttggctctca
3001 tttcactctt cagtgttcct gttatttatg aacggcatca ggcacagata gatcattatc
3061 taggacttgc aaataagaat gttaaagatg ctatggctaa aatccaagca aaaatccctg
3121 gattgaagcg caaagctgaa tgaaaacgcc caaaataatt agtaggagtt catctttaaa
3181 ggggatattc atttgattat acgggggagg gtcagggaag aacgaacctt gacgttgcag
3241 tgcagtttca cagatcgttg ttagatcttt atttttagcc atgcactgtt gtgaggaaaa
3301 attacctgtc ttgactgcca tgtgttcatc atcttaagta ttgtaagctg ctatgtatgg
3361 atttaaaccg taatcatatc tttttcctat ctgaggcact ggtggaataa aaaacctgta
3421 tattttactt tgttgcagat agtcttgccg catcttggca agttgcagag atggtggagc
3481 tagaaaaaaa aaaaaaaaag cccttttcag tttgtgcact gtgtatggtc cgtgtagatt
3541 gatgcagatt ttctgaaatg aaatgtttgt ttagacgaga tcataccggt aaagcaggaa
3601 tgacaaagct tgcttttctg gtatgttcta ggtgtattgt gacttttact gttatattaa
3661 ttgccaatat aagtaaatat agattatata tgtatagtgt ttcacaaagc ttagaccttt
3721 accttccagc caccccacag tgcttgatat ttcagagtca gtcattggtt atacatgtgt
3781 agttccaaag cacataagct agaagaagaa atatttctag gagcactacc atctgttttc
3841 aacatgaaat gccacacaca tagaactcca acaacatcaa tttcattgca cagactgact
3901 gtagttaatt ttgtcacaga atctatggac tgaatctaat gcttccaaaa atgttgtttg
3961 tttgcaaata tcaaacattg ttatgcaaga aattattaat tacaaaatga agatttatac
4021 cattgtggtt taagctgtac tgaactaaat ctgtggaatg cattgtgaac tgtaaaagca
4081 aagtatcaat aaagcttata gacttaaaa
//