LOCUS AY123246 4160 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform Ab (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY123246
VERSION AY123246.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4160)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 4160)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
REFERENCE 3 (bases 1 to 4160)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
FEATURES Location/Qualifiers
source 1..4160
/db_xref="H-InvDB:HIT000084566"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/tissue_type="testis"
gene 1..4160
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..233
/gene="RTN4"
/gene_synonym="NOGO"
CDS 234..3194
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-Ab; alternatively spliced"
/codon_start=1
/product="RTN4 isoform Ab"
/protein_id="AAM64250.1"
/translation="MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHE
YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSP
KAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAK
DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC
FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPL
LGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCP
SFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPD
FSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLT
ETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPL
QMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLARE
YTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATS
KVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTS
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK
FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMA
KIQAKIPGLKRKAE"
3'UTR 3195..4160
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 1335 a 780 c 878 g 1167 t
ORIGIN
1 agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc
61 ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac
121 cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac aatgagaccc
181 tttttgctct tcctgctgca tctgagcctg tgatacgctc ctctgcagaa aatatggact
241 tgaaggagca gccaggtaac actatttcgg ctggtcaaga ggatttccca tctgtcctgc
301 ttgaaactgc tgcttctctt ccttctctgt ctcctctctc agccgcttct ttcaaagaac
361 atgaatacct tggtaatttg tcaacagtat tacccactga aggaacactt caagaaaatg
421 tcagtgaagc ttctaaagag gtctcagaga aggcaaaaac tctactcata gatagagatt
481 taacagagtt ttcagaatta gaatactcag aaatgggatc atcgttcagt gtctctccaa
541 aagcagaatc tgccgtaata gtagcaaatc ctagggaaga aataatcgtg aaaaataaag
601 atgaagaaga gaagttagtt agtaataaca tccttcataa tcaacaagag ttacctacag
661 ctcttactaa attggttaaa gaggatgaag ttgtgtcttc agaaaaagca aaagacagtt
721 ttaatgaaaa gagagttgca gtggaagctc ctatgaggga ggaatatgca gacttcaaac
781 catttgagcg agtatgggaa gtgaaagata gtaaggaaga tagtgatatg ttggctgctg
841 gaggtaaaat cgagagcaac ttggaaagta aagtggataa aaaatgtttt gcagatagcc
901 ttgagcaaac taatcacgaa aaagatagtg agagtagtaa tgatgatact tctttcccca
961 gtacgccaga aggtataaag gatcgttcag gagcatatat cacatgtgct ccctttaacc
1021 cagcagcaac tgagagcatt gcaacaaaca tttttccttt gttaggagat cctacttcag
1081 aaaataagac cgatgaaaaa aaaatagaag aaaagaaggc ccaaatagta acagagaaga
1141 atactagcac caaaacatca aacccttttc ttgtagcagc acaggattct gagacagatt
1201 atgtcacaac agataattta acaaaggtga ctgaggaagt cgtggcaaac atgcctgaag
1261 gcctgactcc agatttagta caggaagcat gtgaaagtga attgaatgaa gttactggta
1321 caaagattgc ttatgaaaca aaaatggact tggttcaaac atcagaagtt atgcaagagt
1381 cactctatcc tgcagcacag ctttgcccat catttgaaga gtcagaagct actccttcac
1441 cagttttgcc tgacattgtt atggaagcac cattgaattc tgcagttcct agtgctggtg
1501 cttccgtgat acagcccagc tcatcaccat tagaagcttc ttcagttaat tatgaaagca
1561 taaaacatga gcctgaaaac cccccaccat atgaagaggc catgagtgta tcactaaaaa
1621 aagtatcagg aataaaggaa gaaattaaag agcctgaaaa tattaatgca gctcttcaag
1681 aaacagaagc tccttatata tctattgcat gtgatttaat taaagaaaca aagctttctg
1741 ctgaaccagc tccggatttc tctgattatt cagaaatggc aaaagttgaa cagccagtgc
1801 ctgatcattc tgagctagtt gaagattcct cacctgattc tgaaccagtt gacttattta
1861 gtgatgattc aatacctgac gttccacaaa aacaagatga aactgtgatg cttgtgaaag
1921 aaagtctcac tgagacttca tttgagtcaa tgatagaata tgaaaataag gaaaaactca
1981 gtgctttgcc acctgaggga ggaaagccat atttggaatc ttttaagctc agtttagata
2041 acacaaaaga taccctgtta cctgatgaag tttcaacatt gagcaaaaag gagaaaattc
2101 ctttgcagat ggaggagctc agtactgcag tttattcaaa tgatgactta tttatttcta
2161 aggaagcaca gataagagaa actgaaacgt tttcagattc atctccaatt gaaattatag
2221 atgagttccc tacattgatc agttctaaaa ctgattcatt ttctaaatta gccagggaat
2281 atactgacct agaagtatcc cacaaaagtg aaattgctaa tgccccggat ggagctgggt
2341 cattgccttg cacagaattg ccccatgacc tttctttgaa gaacatacaa cccaaagttg
2401 aagagaaaat cagtttctca gatgactttt ctaaaaatgg gtctgctaca tcaaaggtgc
2461 tcttattgcc tccagatgtt tctgctttgg ccactcaagc agagatagag agcatagtta
2521 aacccaaagt tcttgtgaaa gaagctgaga aaaaacttcc ttccgataca gaaaaagagg
2581 acagatcacc atctgctata ttttcagcag agctgagtaa aacttcagtt gttgacctcc
2641 tgtactggag agacattaag aagactggag tggtgtttgg tgccagccta ttcctgctgc
2701 tttcattgac agtattcagc attgtgagcg taacagccta cattgccttg gccctgctct
2761 ctgtgaccat cagctttagg atatacaagg gtgtgatcca agctatccag aaatcagatg
2821 aaggccaccc attcagggca tatctggaat ctgaagttgc tatatctgag gagttggttc
2881 agaagtacag taattctgct cttggtcatg tgaactgcac gataaaggaa ctcaggcgcc
2941 tcttcttagt tgatgattta gttgattctc tgaagtttgc agtgttgatg tgggtattta
3001 cctatgttgg tgccttgttt aatggtctga cactactgat tttggctctc atttcactct
3061 tcagtgttcc tgttatttat gaacggcatc aggcacagat agatcattat ctaggacttg
3121 caaataagaa tgttaaagat gctatggcta aaatccaagc aaaaatccct ggattgaagc
3181 gcaaagctga atgaaaacgc ccaaaataat tagtaggagt tcatctttaa aggggatatt
3241 catttgatta tacgggggag ggtcagggaa gaacgaacct tgacgttgca gtgcagtttc
3301 acagatcgtt gttagatctt tatttttagc catgcactgt tgtgaggaaa aattacctgt
3361 cttgactgcc atgtgttcat catcttaagt attgtaagct gctatgtatg gatttaaacc
3421 gtaatcatat ctttttccta tctgaggcac tggtggaata aaaaacctgt atattttact
3481 ttgttgcaga tagtcttgcc gcatcttggc aagttgcaga gatggtggag ctagaaaaaa
3541 aaaaaaaaaa gcccttttca gtttgtgcac tgtgtatggt ccgtgtagat tgatgcagat
3601 tttctgaaat gaaatgtttg tttagacgag atcataccgg taaagcagga atgacaaagc
3661 ttgcttttct ggtatgttct aggtgtattg tgacttttac tgttatatta attgccaata
3721 taagtaaata tagattatat atgtatagtg tttcacaaag cttagacctt taccttccag
3781 ccaccccaca gtgcttgata tttcagagtc agtcattggt tatacatgtg tagttccaaa
3841 gcacataagc tagaagaaga aatatttcta ggagcactac catctgtttt caacatgaaa
3901 tgccacacac atagaactcc aacaacatca atttcattgc acagactgac tgtagttaat
3961 tttgtcacag aatctatgga ctgaatctaa tgcttccaaa aatgttgttt gtttgcaaat
4021 atcaaacatt gttatgcaag aaattattaa ttacaaaatg aagatttata ccattgtggt
4081 ttaagctgta ctgaactaaa tctgtggaat gcattgtgaa ctgtaaaagc aaagtatcaa
4141 taaagcttat agacttaaaa
//