LOCUS AY123245 4102 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform Aa (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY123245
VERSION AY123245.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4102)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 4102)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
REFERENCE 3 (bases 1 to 4102)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
FEATURES Location/Qualifiers
source 1..4102
/db_xref="H-InvDB:HIT000084565"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/tissue_type="testis"
gene 1..4102
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..175
/gene="RTN4"
/gene_synonym="NOGO"
CDS 176..3136
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-Aa; alternatively spliced"
/codon_start=1
/product="RTN4 isoform Aa"
/protein_id="AAM64249.1"
/translation="MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHE
YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSP
KAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAK
DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC
FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPL
LGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCP
SFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPD
FSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLT
ETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPL
QMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLARE
YTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATS
KVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTS
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK
FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMA
KIQAKIPGLKRKAE"
3'UTR 3137..4102
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 1333 a 773 c 841 g 1155 t
ORIGIN
1 atacggaccc ccagctgcgg gcaaggccaa gaccccaccc caactcacgg ttacccaaag
61 tgggggtgga gctcccagct ctcagccccg cccattgaac gcaatcccag ccgatgagac
121 cctttttgct cttcctgctg catctgagcc tgtgatacgc tcctctgcag aaaatatgga
181 cttgaaggag cagccaggta acactatttc ggctggtcaa gaggatttcc catctgtcct
241 gcttgaaact gctgcttctc ttccttctct gtctcctctc tcagccgctt ctttcaaaga
301 acatgaatac cttggtaatt tgtcaacagt attacccact gaaggaacac ttcaagaaaa
361 tgtcagtgaa gcttctaaag aggtctcaga gaaggcaaaa actctactca tagatagaga
421 tttaacagag ttttcagaat tagaatactc agaaatggga tcatcgttca gtgtctctcc
481 aaaagcagaa tctgccgtaa tagtagcaaa tcctagggaa gaaataatcg tgaaaaataa
541 agatgaagaa gagaagttag ttagtaataa catccttcat aatcaacaag agttacctac
601 agctcttact aaattggtta aagaggatga agttgtgtct tcagaaaaag caaaagacag
661 ttttaatgaa aagagagttg cagtggaagc tcctatgagg gaggaatatg cagacttcaa
721 accatttgag cgagtatggg aagtgaaaga tagtaaggaa gatagtgata tgttggctgc
781 tggaggtaaa atcgagagca acttggaaag taaagtggat aaaaaatgtt ttgcagatag
841 ccttgagcaa actaatcacg aaaaagatag tgagagtagt aatgatgata cttctttccc
901 cagtacgcca gaaggtataa aggatcgttc aggagcatat atcacatgtg ctccctttaa
961 cccagcagca actgagagca ttgcaacaaa catttttcct ttgttaggag atcctacttc
1021 agaaaataag accgatgaaa aaaaaataga agaaaagaag gcccaaatag taacagagaa
1081 gaatactagc accaaaacat caaacccttt tcttgtagca gcacaggatt ctgagacaga
1141 ttatgtcaca acagataatt taacaaaggt gactgaggaa gtcgtggcaa acatgcctga
1201 aggcctgact ccagatttag tacaggaagc atgtgaaagt gaattgaatg aagttactgg
1261 tacaaagatt gcttatgaaa caaaaatgga cttggttcaa acatcagaag ttatgcaaga
1321 gtcactctat cctgcagcac agctttgccc atcatttgaa gagtcagaag ctactccttc
1381 accagttttg cctgacattg ttatggaagc accattgaat tctgcagttc ctagtgctgg
1441 tgcttccgtg atacagccca gctcatcacc attagaagct tcttcagtta attatgaaag
1501 cataaaacat gagcctgaaa accccccacc atatgaagag gccatgagtg tatcactaaa
1561 aaaagtatca ggaataaagg aagaaattaa agagcctgaa aatattaatg cagctcttca
1621 agaaacagaa gctccttata tatctattgc atgtgattta attaaagaaa caaagctttc
1681 tgctgaacca gctccggatt tctctgatta ttcagaaatg gcaaaagttg aacagccagt
1741 gcctgatcat tctgagctag ttgaagattc ctcacctgat tctgaaccag ttgacttatt
1801 tagtgatgat tcaatacctg acgttccaca aaaacaagat gaaactgtga tgcttgtgaa
1861 agaaagtctc actgagactt catttgagtc aatgatagaa tatgaaaata aggaaaaact
1921 cagtgctttg ccacctgagg gaggaaagcc atatttggaa tcttttaagc tcagtttaga
1981 taacacaaaa gataccctgt tacctgatga agtttcaaca ttgagcaaaa aggagaaaat
2041 tcctttgcag atggaggagc tcagtactgc agtttattca aatgatgact tatttatttc
2101 taaggaagca cagataagag aaactgaaac gttttcagat tcatctccaa ttgaaattat
2161 agatgagttc cctacattga tcagttctaa aactgattca ttttctaaat tagccaggga
2221 atatactgac ctagaagtat cccacaaaag tgaaattgct aatgccccgg atggagctgg
2281 gtcattgcct tgcacagaat tgccccatga cctttctttg aagaacatac aacccaaagt
2341 tgaagagaaa atcagtttct cagatgactt ttctaaaaat gggtctgcta catcaaaggt
2401 gctcttattg cctccagatg tttctgcttt ggccactcaa gcagagatag agagcatagt
2461 taaacccaaa gttcttgtga aagaagctga gaaaaaactt ccttccgata cagaaaaaga
2521 ggacagatca ccatctgcta tattttcagc agagctgagt aaaacttcag ttgttgacct
2581 cctgtactgg agagacatta agaagactgg agtggtgttt ggtgccagcc tattcctgct
2641 gctttcattg acagtattca gcattgtgag cgtaacagcc tacattgcct tggccctgct
2701 ctctgtgacc atcagcttta ggatatacaa gggtgtgatc caagctatcc agaaatcaga
2761 tgaaggccac ccattcaggg catatctgga atctgaagtt gctatatctg aggagttggt
2821 tcagaagtac agtaattctg ctcttggtca tgtgaactgc acgataaagg aactcaggcg
2881 cctcttctta gttgatgatt tagttgattc tctgaagttt gcagtgttga tgtgggtatt
2941 tacctatgtt ggtgccttgt ttaatggtct gacactactg attttggctc tcatttcact
3001 cttcagtgtt cctgttattt atgaacggca tcaggcacag atagatcatt atctaggact
3061 tgcaaataag aatgttaaag atgctatggc taaaatccaa gcaaaaatcc ctggattgaa
3121 gcgcaaagct gaatgaaaac gcccaaaata attagtagga gttcatcttt aaaggggata
3181 ttcatttgat tatacggggg agggtcaggg aagaacgaac cttgacgttg cagtgcagtt
3241 tcacagatcg ttgttagatc tttattttta gccatgcact gttgtgagga aaaattacct
3301 gtcttgactg ccatgtgttc atcatcttaa gtattgtaag ctgctatgta tggatttaaa
3361 ccgtaatcat atctttttcc tatctgaggc actggtggaa taaaaaacct gtatatttta
3421 ctttgttgca gatagtcttg ccgcatcttg gcaagttgca gagatggtgg agctagaaaa
3481 aaaaaaaaaa aagccctttt cagtttgtgc actgtgtatg gtccgtgtag attgatgcag
3541 attttctgaa atgaaatgtt tgtttagacg agatcatacc ggtaaagcag gaatgacaaa
3601 gcttgctttt ctggtatgtt ctaggtgtat tgtgactttt actgttatat taattgccaa
3661 tataagtaaa tatagattat atatgtatag tgtttcacaa agcttagacc tttaccttcc
3721 agccacccca cagtgcttga tatttcagag tcagtcattg gttatacatg tgtagttcca
3781 aagcacataa gctagaagaa gaaatatttc taggagcact accatctgtt ttcaacatga
3841 aatgccacac acatagaact ccaacaacat caatttcatt gcacagactg actgtagtta
3901 attttgtcac agaatctatg gactgaatct aatgcttcca aaaatgttgt ttgtttgcaa
3961 atatcaaaca ttgttatgca agaaattatt aattacaaaa tgaagattta taccattgtg
4021 gtttaagctg tactgaacta aatctgtgga atgcattgtg aactgtaaaa gcaaagtatc
4081 aataaagctt atagacttaa aa
//