LOCUS AY116661 7095 bp mRNA linear HUM 14-NOV-2002
DEFINITION Homo sapiens plexin D1 (PLXND1) mRNA, complete cds.
ACCESSION AY116661
VERSION AY116661.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7095)
AUTHORS van der Zwaag,B., Hellemons,A.J., Leenders,W.P., Burbach,J.P.,
Brunner,H.G., Padberg,G.W. and Van Bokhoven,H.
TITLE PLEXIN-D1, a novel plexin family member, is expressed in vascular
endothelium and the central nervous system during mouse
embryogenesis
JOURNAL Dev. Dyn. 225 (3), 336-343 (2002)
PUBMED 12412018
REFERENCE 2 (bases 1 to 7095)
AUTHORS van der Zwaag,B. and van Bokhoven,H.
TITLE Direct Submission
JOURNAL Submitted (31-MAY-2002) Neurology, UMC Nijmegen, Reinier Postlaan
4, Nijmegen, Gelderland 6525 GC, The Netherlands
FEATURES Location/Qualifiers
source 1..7095
/db_xref="H-InvDB:HIT000084480"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q21"
gene 1..7095
/gene="PLXND1"
CDS 181..5958
/gene="PLXND1"
/note="plexin family member"
/codon_start=1
/product="plexin D1"
/protein_id="AAM49063.1"
/translation="MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARA
GALEIQRRFPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSP
LCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVA
VRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGS
SFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHK
LGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKL
TESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFR
FADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHL
QHPLSILQPLKATPVFRAPGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSR
RVVTVAYGEPVHHVMQFDPADSVYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYC
GWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQIS
GSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVE
MSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRC
EASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGAALECSFGLEEIFEA
VWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDC
SQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGR
NLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGKS
RDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDT
SIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTIT
VAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAY
ADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQD
SLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIAT
LQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIRE
EIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTL
NSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDF
AVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKML
TNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIE
AKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEW
FASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDL
DTEKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAIL
SIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFD
IDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQI
QDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARR
TQLQHKFEQVVALMEDNIYECYSEA"
regulatory 7032..7037
/regulatory_class="polyA_signal_sequence"
/gene="PLXND1"
/note="putative"
BASE COUNT 1347 a 2358 c 2146 g 1244 t
ORIGIN
1 ccgggctgcg cggcgaggct gagccgggcc cgggcgccgg ggccgggggc ggctggcgcg
61 ggcaggaagc gcctcgcgga cccgggcccg ccccccgcct cccgccgcct ccgggctccc
121 ggctcccggc cgcgcctcgc cccatgcact cgccgcgccg cgcagcccgc gcacgcccgg
181 atggctcctc gcgccgcggg cggcgcaccc cttagcgccc gggccgccgc cgccagcccc
241 ccgccgttcc agacgccgcc gcggtgcccg gtgccgctgc tgttgctgct gctcctgggg
301 gcggcgcggg ccggcgccct ggagatccag cgtcggttcc cctcgcccac gcccaccaac
361 aacttcgccc tggacggcgc ggcggggacc gtgtacctgg cggccgtcaa ccgcctctat
421 cagctgtcgg gcgccaacct gagcctggag gccgaggcgg ccgtgggccc ggtgcccgac
481 agcccgctgt gtcacgctcc gcagctgccg caggcctcgt gcgagcaccc gcggcgcctc
541 acggacaact acaacaagat cctgcagctg gaccccggcc agggcctggt agtcgtgtgc
601 gggtccatct accagggctt ctgccagctg cggcgccggg gtaacatctc ggccgtggcc
661 gtgcgcttcc cgcccgccgc gccgcccgcc gagcccgtca cggtgttccc cagcatgctg
721 aacgtggcgg ccaaccaccc gaacgcgtcc accgtggggc tagttctgcc tcccgccgcg
781 ggcgcggggg gcagccgcct gctcgtgggc gccacgtaca ccggttacgg cagctccttc
841 ttcccgcgca accgcagcct ggaggaccac cgcttcgaga acacgcccga gatcgccatc
901 cgctccctgg acacgcgcgg cgacctggcc aagctcttca ccttcgacct caacccctcc
961 gacgacaaca tcctcaagat caagcagggc gccaaggagc agcacaagct gggcttcgtg
1021 agcgccttcc tgcacccgtc cgacccgccg ccgggtgcac agtcctacgc gtacctggcg
1081 ctcaacagcg aggcgcgcgc gggcgacaag gagagccagg cgcggagcct gctggcgcgc
1141 atctgcctgc cccacggcgc cggcggcgac gccaagaagc tcaccgagtc ctacatccag
1201 ttgggcttgc agtgcgcggg cggcgcgggc cgcggcgacc tctacagccg cctggtgtcg
1261 gtcttcccag cccgggagcg gctctttgct gtcttcgagc ggccccaggg gtcccccgcg
1321 gcccgcgctg ctccggccgc actctgcgcc ttccgcttcg ccgacgtgcg agccgccatc
1381 cgagctgcgc gcaccgcctg cttcgtggaa ccggcgcccg acgtggtggc ggtgctcgac
1441 agcgtggtgc agggcacggg accggcctgc gagcgcaagc tcaacatcca gctccagcca
1501 gagcagctgg actgtggagc tgctcacctg cagcacccgc tgtccatcct gcagcccctg
1561 aaggccacgc ccgtgttccg cgccccgggc ctcacctccg tggccgtggc cagcgtcaac
1621 aactacacag cggtcttcct gggcacggtc aacgggaggc ttctcaagat caacctgaac
1681 gagagcatgc aggtggtgag caggcgggtg gtgactgtgg cctatgggga gcccgtgcac
1741 catgtcatgc agtttgaccc agcagactcc gtttaccttt acctgatgac gtcccaccag
1801 atggccaggg tgaaggtcgc cgcctgcaac gtgcactcca cctgtgggga ctgcgtgggt
1861 gcggcggacg cctactgcgg ctggtgtgcc ctggagacgc ggtgcacctt gcagcaggac
1921 tgcaccaatt ccagccagca gcatttctgg accagtgcca gcgagggccc cagccgctgt
1981 cctgccatga ccgtcctgcc ttccgagatc gatgtgcgcc aggagtaccc aggcatgatc
2041 ctgcagatct cgggcagcct gcccagcctc agtggcatgg agatggcctg tgactatggg
2101 aacaacatcc gcactgtggc tcgggtccca ggccctgcct ttggtcacca gattgcctac
2161 tgcaacctcc tgccgaggga ccagtttccg cccttccccc ccaaccagga ccacgtgact
2221 gttgagatgt ctgtgagggt caatgggcgg aacatcgtca aggccaattt caccatctac
2281 gactgcagcc gcactgcaca agtgtacccc cacacagcct gtaccagctg cctgtcggca
2341 cagtggccct gtttctggtg cagccagcag cactcctgtg tttccaacca gtctcggtgc
2401 gaggcctcac caaaccccac gagccctcag gactgccccc ggaccctgct ctcacccctg
2461 gcacccgtgc ctacgggtgg ctcccagaac atcctggtgc ctctggccaa cactgccttt
2521 ttccagggtg cagccctgga gtgtagtttt gggctggagg agatcttcga ggctgtgtgg
2581 gtgaatgagt ctgttgtacg ctgtgaccag gtggtgctgc acacgacccg gaagagccag
2641 gtgttcccgc tcagcctcca actaaagggg cggccagccc gattcctgga cagccctgag
2701 cccatgacag tcatggtcta taactgtgcc atgggcagcc ccgactgttc ccagtgcctg
2761 ggccgcgaag acctgggtca cctgtgcatg tggagtgatg gctgccgcct gcgggggcct
2821 ctgcagccca tggctggcac ctgccccgcc cccgagatcc gcgcgattga gcccctgagt
2881 ggcccgttgg acggtgggac cctgctgacc atccgaggaa ggaacctggg ccggcggctc
2941 agtgacgtgg cccacggcgt gtggattggt ggtgtggcct gtgagccact gcctgacaga
3001 tacacggtgt cggaggagat cgtgtgtgtc acagggccag ccccaggacc actctcaggt
3061 gtggtgaccg tgaacgcctc taaggagggc aagtcccggg accgcttctc ctacgtgctg
3121 cccctggtcc actccctgga gcctaccatg ggccccaagg ccgggggcac caggatcacc
3181 atccatggga atgacctcca tgtaggctcc gagctccagg tcctggtgaa cgacacagac
3241 ccctgcacgg agctgatgcg cacagatacc agcatcgcct gcaccatgcc tgagggggcc
3301 ctgccggctc cggtgcctgt gtgtgtgcgc ttcgagcgtc ggggctgcgt gcacggcaac
3361 ctcaccttct ggtacatgca gaacccggtc atcacggcca tcagtccccg ccgcagccct
3421 gtcagtggcg gcaggaccat cacagtggct ggtgagcgtt tccacatggt gcagaatgtg
3481 tccatggccg tccaccacat tggccgggag cccacgctct gcaaggttct caactccacc
3541 ctcatcacct gcccgtcccc cggggccctg agcaacgcat cagcgccagt ggacttcttc
3601 atcaatgggc gggcctacgc agacgaggtg gctgtggctg aggagctact ggaccccgag
3661 gaggcacagc ggggcagcag gttccgcctg gactacctcc ccaacccaca gttctctacg
3721 gccaagaggg agaagtggat caagcaccac cccggggagc ctctcaccct cgttatccac
3781 aaggagcagg acagcctggg gctccagagt cacgagtacc gggtcaagat aggccaagta
3841 agctgcgaca tccagattgt ctctgacaga atcatccact gctcggtcaa cgagtccctg
3901 ggcgcggccg tggggcagct gcccatcaca atccaggtag ggaacttcaa ccagaccatc
3961 gccacactgc agctgggggg tagcgagacg gccatcatcg tgtccatcgt catctgcagc
4021 gtcctgctgc tgctctccgt ggtggccctg ttcgtcttct gtaccaagag ccgacgtgct
4081 gagcgttact ggcagaagac gctgctgcag atggaggaga tggaatctca gatccgagag
4141 gaaatccgca aaggcttcgc tgagctgcag acagacatga cagatctcac caaggagctg
4201 aaccgcagcc agggcatccc cttcctggag tataagcact tcgtgacccg caccttcttc
4261 cccaagtgtt cctcccttta tgaagagcgt tacgtgctgc cctcccagac cctcaactcc
4321 cagggcagct cccaggcaca ggaaacccac ccactgctgg gagagtggaa gattcctgag
4381 agctgccggc ccaacatgga agagggaatt agcttgttct cctcactact caacaacaag
4441 cacttcctca tcgtctttgt ccacgcgctg gagcagcaga aggactttgc ggtgcgcgac
4501 aggtgcagcc tggcctcgct gctgaccatc gcgctgcacg gcaagctgga gtactacacc
4561 agcatcatga aggagctgct ggtggacctc attgacgcct cggccgccaa gaaccccaag
4621 ctcatgctgc ggcgcacaga gtctgtggtg gagaagatgc tcaccaactg gatgtccatc
4681 tgcatgtaca gctgtctgcg ggagacggtg ggggagccat tcttcctgct gctgtgtgcc
4741 atcaagcagc aaatcaacaa gggctccatc gacgccatca caggcaaggc ccgctacaca
4801 ctcaatgagg agtggctgct gcgggagaac atcgaggcca agccccggaa cctgaacgtg
4861 tccttccagg gctgtggcat ggactcgctg agcgtgcggg ccatggacac cgacacgctg
4921 acacaggtca aggagaagat cctggaggcc ttctgcaaga atgtgcccta ctcccagtgg
4981 ccgcgtgcag aggacgtcga ccttgagtgg ttcgcctcca gcacacagag ctacatcctt
5041 cgggacctgg acgacacctc agtggtggaa gacggccgca agaagcttaa cacgctggcc
5101 cattacaaga tccctgaagg tgcctccctg gccatgagtc tcatagacaa gaaggacaac
5161 acactgggcc gagtgaaaga cttggacaca gagaagtatt tccatttggt gctgcctacg
5221 gacgagctgg cggagcccaa gaagtctcac cggcagagcc atcgcaagaa ggtgctcccg
5281 gaaatctacc tgacccgcct gctctccacc aagggcacgt tgcagaagtt tctggatgac
5341 ctgttcaagg ccattctgag tatccgtgaa gacaagcccc cactggctgt caagtacttt
5401 ttcgacttcc tggaggagca ggctgagaag aggggaatct ccgaccccga caccctacac
5461 atctggaaga ccaacagcct tcctctccgg ttctgggtga acatcctgaa gaacccccag
5521 tttgtctttg acatcgacaa gacagaccac atcgacgcct gcctttcagt catcgcgcag
5581 gccttcatcg acgcctgctc catctctgac ctgcagctgg gcaaggattc gccaaccaac
5641 aagctcctct acgccaagga gattcctgag taccggaaga tcgtgcagcg ctactacaag
5701 cagatccagg acatgacgcc gctcagcgag caagagatga atgcccatct ggccgaggag
5761 tcgaggaaat accagaatga gttcaacacc aatgtggcca tggcagagat ttataagtac
5821 gccaagaggt atcggccgca gatcatggcc gcgctggagg ccaaccccac ggcccggagg
5881 acacaactgc agcacaagtt tgagcaggtg gtggctttga tggaggacaa catctacgag
5941 tgctacagtg aggcctgaga cacatggaga gttggtcagg ctgctgctgg gagaaatgga
6001 cgcccactgg gcctcaactt gatcttctac cccgtgcctg tgactcagac tgggaaatac
6061 tgagcagaga cggctggggc gggggcagga ggaggggctg ctctctgaga caggggcgcc
6121 cccgccttga cccctgggca cctccatccc ctcccacctg tccccagatc agtctctggg
6181 atggaggcca gagagctggt caggctcccc catctgccca gcacggcctg cactgtgccc
6241 acccacttgc tccacaacgt ccagttggtc ctgctgccaa gagccccgtg catccaggcg
6301 gccaagcaca aactggggga gaggaggccg ccagcccgga ggctgcagcc cagaaactct
6361 acctcatcca cactggtgca gggagccctc cttgaactga cctttgattg gtttctgctt
6421 caactaccaa aatgttatct ccacttcccc ctcacccgta gaggatcctg gccacagaca
6481 gtttcaagta gtgtcagatt tttgttgctt gggcggctgt tggtagagtg ggcagtgccc
6541 gcgccatggg gtgctctgtg ggcttctcca ggagcaggga gggtggaggg gagggatggg
6601 gggcacagga gctgggagcc ccgtctccag gaaaaggaga ggggttaaga tgcaccgagg
6661 ctgtagctgg gctacttgat cttgctgaaa gtgtttctaa agatagcacc actttttttt
6721 ttaaagcttt tatatattaa aaaacgtatc atgcaccaac tgtgaatagc tgccgcttgc
6781 gcagaggacc cggggagggg tcccgagagg ctccccatgc aacactggaa atgactgttc
6841 cagagagcgg gcagacctgg cagagcgccc ctggcgcctg agactaccac ccactccgtt
6901 cctgccagaa acgaccctct gtggccgatg ggccatgcgg gcccctcgca gccaactcag
6961 ccagtgttgg gactggctca gagcccatgg gggctggagg ggggcagctg ggactctgga
7021 atcttcttta taataaaagc cttacggaca aacctactgt gggctccagc gtttgtcctg
7081 agatagccaa gcggg
//