LOCUS AY116215 3252 bp mRNA linear HUM 01-SEP-2002
DEFINITION Homo sapiens TTL/TEL fusion protein TTL-B1 (TTL/TEL fusion) mRNA,
complete cds.
ACCESSION AY116215
VERSION AY116215.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3252)
AUTHORS Qiao,Y., Ogawa,S., Hangaishi,A., Yuji,K., Izutsu,K., Kunisato,A.,
Imai,Y., Wang,L., Hosoya,N., Sato,Y., Nakamura,Y., Mitani,K. and
Hirai,H.
TITLE Identification of a Novel Fusion Gene, TTL, Fused to TEL, in Acute
Lymphoblastic Leukemia with t(12;13)(p13;q14) and Its Implication
in Leukemogenesis
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3252)
AUTHORS Qiao,Y., Ogawa,S., Hangaishi,A., Yuji,K., Izutsu,K., Kunisato,A.,
Imai,Y., Wang,L., Hosoya,N., Sato,Y., Nakamura,Y., Mitani,K. and
Hirai,H.
TITLE Direct Submission
JOURNAL Submitted (29-MAY-2002) Hematology & Oncology, University of Tokyo,
Bunkyo-ku, Hongo 7-3-1, Tokyo 113-8655, Japan
FEATURES Location/Qualifiers
source 1..3252
/db_xref="H-InvDB:HIT000084474"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="t(12;13)(p13;q14)"
/tissue_type="brain"
source 1..70
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p13"
source 71..3252
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q14"
gene 1..3252
/gene="TTL/TEL fusion"
/note="twelve-thirteen translocation leukemia gene"
CDS 11..133
/gene="TTL/TEL fusion"
/codon_start=1
/product="TTL/TEL fusion protein TTL-B1"
/protein_id="AAM97781.1"
/translation="MSEDCFRKSGLLLGNVPQLLNTIGAPLEHVLVFSECEVCV"
exon <71..3252
/note="TEL gene"
/number=2
BASE COUNT 741 a 838 c 656 g 1017 t
ORIGIN
1 cattgctgag atgagtgagg attgtttcag aaaatcaggc ctcctcctgg ggaatgtgcc
61 tcagcttctg aataccatcg gagctcctct ggaacatgtc cttgtcttct cagagtgtga
121 agtgtgtgtg tgacagtgct tttctgagga ctcaggtgac ctggaggctg gagaacagca
181 tggagcaagg aaaacaaaga cgatgtgctg gagtgtatgt tgctttcata attatgtgaa
241 agaaaatgta gagaaatttg aaaggtaaga tctgaccgct ttgacccctc tcctcacacc
301 agcctatgcc ccactttctt gaagacccac tccccagctt agcagccagg tacccatcac
361 agcctggctt caagaaggga gcccagtccg ccaggtttgt tctctctcct tcggtctgtc
421 tctgttggcc agtctgtcca ggagtcactc tgtccatggg tcagtctctc cttctttctg
481 actgtcttcc tatcattctt tctcagttgt tccctctcac cttaagggct gcctaatttc
541 tctctcatca tgtctttact tctctcctag cctcatttcc agctttggct tcctcataac
601 taaagtgtgc tgtggcccca acatggcatc ctgacttctt ttcagagtct gcctccaagc
661 ttctggctgg tcttgccaca tactccaatt catatccctt cacattacat caagctggct
721 cagtctgtct cttctcctct ggccagacaa tggcagatca ccttggtcaa gcatgtcctc
781 tggaccaatt gccccagacc aggattattt aaatacaact cgtccatctg cagttgtcct
841 taaaatctga tttatagaag gtctgtgtgg gcttggcatt tctggtgtcc actcattctg
901 tctagtgaat tgtccttctt ccatgacgcc agtggtgata gatctcaccc tcctctgatc
961 cctgggcctg ttggttgtgg agtttatggg ccacttctgc aacttgatgg ccttgggcca
1021 tggaaaggcc tgtcacccct tttctggcac tagaatggaa gcttcagtag ggcaggaacc
1081 ctatttaggc atttcagtta gggcttggca cactgtcttg catggagaaa gctcagaata
1141 agacagagat cctaaagtat cttcaacaga actaatctga caaatttcca aggctccttt
1201 gggagataaa atctacttgg gggaatggga aaaggatgtc tacatagatt tagaataacg
1261 accaccacca ccatcatcat ccttgacaga acctttatgc caggtgctgt tctaaagcac
1321 tttacatact ttatctcatt taatcctaac aacagccctg taagataact gttactatgc
1381 cctttttacc tttaatgaag aaacagcctc agggagatta agaaattcac ccaaggtcac
1441 agagctagaa tgtgaaagag ctggatttcc aacccaagtg tgcctgatgt caactctgat
1501 ctaagatgtg gacgcacatg ggcagaatga tgacgtgctc tttccaacct ctcatttagc
1561 cagcatgtga gagggcaagg tgtcttcagc aaccatttca tttgtaaaca tacgtgtttt
1621 tatccttggt ctacgcaata gtattaccac acaggtaata ccagtgggtg ctgggtgttt
1681 tttttttttt cctcttctac atattccctc caaaataaat tattaattgc ccctcttcta
1741 aatcttatgt cacagtcttt aatgcctgca tctgaattgc tgttaaaaca tctcttggag
1801 tcgttccctg tgatattaca gtccgggttc ctgcggcgta atcccacttg ctggtttttc
1861 cctttgcatt gcatttgggt gatgaatggc cctttgatgt tcctggcatc tgccttcctg
1921 cctcaggaac tcactgctgg gtcctctttt ccctgctaat ggccctgttt gccttccacg
1981 acagttgaga ctcagaaaca cttgcaccca cggcaccttt ggacattgca gtttgcctct
2041 gtttcactgc cctttcttct atttttcttt actctgcctc ttctgttctt tgctctggcc
2101 tgctcctgtt ccctggcagc tccagccatg cagcaaacag tcaccagtct tcactttatc
2161 ctcagaactg gtgacacagc acctactctc cttatctctg tagaggcttc ctccaaaatt
2221 tctattactt aaccctttct cctagactcc tccttgccgc tcatcatggc tgaggccctg
2281 ctcagatctg tttccctcag ttctttggga aagcagctgt ctgacattga tgtgcatttg
2341 tttagccttt tctatgtgtc aagcataggt ttgtatagtc atagaggtgg ataacatagt
2401 cttaggtgct tttcttcttt ttttatagac tgcgtcttgc tctgtcaccc agactggact
2461 gcagtggcac aatcacagct acctgtaacc tcaaactcct gggctcatgc aatcctccca
2521 cctcagcctc tggagtagct gggactacag gtttgtgcca ctaagcctgg ataatttttt
2581 aaattttttg tagagatggg gttctcgcta tgttgcccag gctttttttt tttttttttt
2641 ttgagacaga gtcttgctct gtcacccagg ctggagtgca atggcacgat ctcagctcac
2701 tgcaacctcc acctcgttgg ttcaagcaat tctactgcct cagcctcctg agtagctggg
2761 actacaggca tgcaacacca tgcccagctg atttttttat atttttagta gagagggggt
2821 ttcaccatgt tggtcaggct ggtctcgaac tcctgacctc aaatgatcgc ctgcctcagc
2881 ttcccaaagt gctgggatta caggcttaag ccaccgtgcc tggcctgccc aggcttttta
2941 aaaaatagat tttatttttt aagtctttgg tccacataac cacagcctcc cctactatca
3001 acatcccaca ccagagcagt acatttgaca tattcgacgc acctaacttg acacatcatt
3061 atcactcaaa gtccacagct tactctaggg ctcgttcttg gcattgtgca ttctgtgggt
3121 tttgacaaat gtataatgac atgcgtccac cattgtagta tcatcaggag tggtgtcatg
3181 gccctataca tccttcatgt cttagggatt tttaaagcct agtaaaagac atcggaaaaa
3241 aaaaaaaaaa aa
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