LOCUS AY116204 3731 bp mRNA linear HUM 21-MAY-2003
DEFINITION Homo sapiens monarch-1 mRNA, complete cds; alternatively spliced.
ACCESSION AY116204
VERSION AY116204.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3731)
AUTHORS Williams,K.L., Taxman,D.J., Linhoff,M.W., Reed,W. and Ting,J.P.
TITLE Cutting edge: Monarch-1: a pyrin/nucleotide-binding
domain/leucine-rich repeat protein that controls classical and
nonclassical MHC class I genes
JOURNAL J. Immunol. 170 (11), 5354-5358 (2003)
PUBMED 12759408
REFERENCE 2 (bases 1 to 3731)
AUTHORS Williams,K.L., Linhoff,M.W., Harton,J.A. and Ting,J.P.Y.
TITLE Direct Submission
JOURNAL Submitted (29-MAY-2002) Lineberger Cancer Center, UNC, Mason Farm
Road, Chapel Hill, NC 27599, USA
FEATURES Location/Qualifiers
source 1..3731
/db_xref="H-InvDB:HIT000084469"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.4"
/cell_line="U937"
CDS 221..3409
/note="alternatively spliced"
/codon_start=1
/product="monarch-1"
/protein_id="AAM75142.1"
/translation="MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIP
WGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGG
PSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRL
LLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGA
AGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPS
APLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLP
ELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVR
DNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAP
RLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCER
YYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGL
LNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEE
FIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSA
GAHTLLVQLRPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRH
PNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHP
QCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPV
CRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTC
KLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACR
LQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKL
RVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC"
misc_feature 869..892
/note="Region: P-loop"
misc_feature 2069..3406
/note="Region: leucine rich repeat"
misc_feature 221..289
/note="Region: pyrin domain"
BASE COUNT 842 a 1046 c 1091 g 752 t
ORIGIN
1 attggtgagt ggggcagggc aggagggaac tgaagagtga gaaagcatta tttcagcaaa
61 aggtctttcc tcccttgctc actcctccaa ccactggctc agcctctccg cccgctgcct
121 gtgaatgatg caatggaagg tgtgctgggg tcgccctgtg tcccgtgcat aggagcatct
181 cagcctccag gtcctctcct ttggggctta cggcaccccc atgctacgaa ccgcaggcag
241 ggacggcctc tgtcgcctgt ccacctactt ggaagaactc gaggctgtgg aactgaagaa
301 gttcaagtta tacctgggga ccgcgacaga gctgggagaa ggcaagatcc cctggggaag
361 catggagaag gccggtcccc tggaaatggc ccagctgctc atcacccact tcgggccaga
421 ggaggcctgg aggttggctc tcagcacctt tgagcggata aacaggaagg acctgtggga
481 gagaggacag agagaggacc tggtgaggga taccccacct ggtggcccgt cctcacttgg
541 gaaccagtca acatgccttc tggaagtctc tcttgtcact ccaagaaaag atccccagga
601 aacctacagg gactatgtcc gcaggaaatt ccggctcatg gaagaccgca atgcgcgcct
661 aggggaatgt gtcaacctca gccaccggta cacccggctc ctgctggtga aggagcactc
721 aaaccccatg caggtccagc agcagcttct ggacacaggc cggggacacg cgaggaccgt
781 gggacaccag gctagcccca tcaagataga gaccctcttt gagccagacg aggagcgccc
841 cgagccaccg cgcaccgtgg tcatgcaagg cgcggcaggg ataggcaagt ccatgctggc
901 acacaaggtg atgctggact gggcggacgg gaagctcttc caaggcagat ttgattatct
961 cttctacatc aactgcaggg agatgaacca gagtgccacg gaatgcagca tgcaagacct
1021 catcttcagc tgctggcctg agcccagcgc gcctctccag gagctcatcc gagttcccga
1081 gcgcctcctt ttcatcatcg acggcttcga tgagctcaag ccttctttcc acgatcctca
1141 gggaccctgg tgcctctgct gggaggagaa acggcccacg gagctgcttc ttaacagctt
1201 aattcggaag aagctgctcc ctgagctatc tttgctcatc accacacggc ccacggcttt
1261 ggagaagctc caccgtctgc tggagcaccc caggcatgtg gagatcctgg gcttctctga
1321 ggcagaaagg aaggaatact tctacaagta tttccacaat gcagagcagg cgggccaagt
1381 cttcaattac gtgagggaca acgagcctct cttcaccatg tgcttcgtcc ccctggtgtg
1441 ctgggtggtg tgtacctgcc tccagcagca gctggagggt ggggggctgt tgagacagac
1501 gtccaggacc accactgcag tgtacatgct ctacctgctg agtctgatgc aacccaagcc
1561 gggggccccg cgcctccagc ccccacccaa ccagagaggg ttgtgctcct tggcggcaga
1621 tgggctctgg aatcagaaaa tcctatttga ggagcaggac ctccggaagc acggcctaga
1681 cggggaagac gtctctgcct tcctcaacat gaacatcttc cagaaggaca tcaactgtga
1741 gaggtactac agcttcatcc acttgagttt ccaggaattc tttgcagcta tgtactatat
1801 cctggacgag ggggagggcg gggcaggccc agaccaggac gtgaccaggc tgttgaccga
1861 gtacgcgttt tctgaaagga gcttcctggc actcaccagc cgcttcctgt ttggactcct
1921 gaacgaggag accaggagcc acctggagaa gagtctctgc tggaaggtct cgccgcacat
1981 caagatggac ctgttgcagt ggatccaaag caaagctcag agcgacggct ccaccctgca
2041 gcagggctcc ttggagttct tcagctgctt gtacgagatc caggaggagg agtttatcca
2101 gcaggccctg agccacttcc aggtgatcgt ggtcagcaac attgcctcca agatggagca
2161 catggtctcc tcgttctgtc tgaagcgctg caggagcgcc caggtgctgc acttgtatgg
2221 cgccacctac agcgcggacg gggaagaccg cgcgaggtgc tccgcaggag cgcacacgct
2281 gttggtgcag ctcagaccag agaggaccgt tctgctggac gcctacagtg aacatctggc
2341 agcggccctg tgcaccaatc caaacctgat agagctgtct ctgtaccgaa atgccctggg
2401 cagccggggg gtgaagctgc tctgtcaagg actcagacac cccaactgca aacttcagaa
2461 cctgaggctg aagaggtgcc gcatctccag ctcagcctgc gaggacctct ctgcagctct
2521 catagccaat aagaatttga caaggatgga tctcagtggc aacggcgttg gattcccagg
2581 catgatgctg ctttgcgagg gcctgcggca tccccagtgc aggctgcaga tgattcagtt
2641 gaggaagtgt cagctggagt ccggggcttg tcaggagatg gcttctgtgc tcggcaccaa
2701 cccacatctg gttgagttgg acctgacagg aaatgcactg gaggatttgg gcctgaggtt
2761 actatgccag ggactgaggc acccagtctg cagactacgg actttgtggc tgaagatctg
2821 ccgcctcact gctgctgcct gtgacgagct ggcctcaact ctcagtgtga accagagcct
2881 gagagagctg gacctgagcc tgaatgagct gggggacctc ggggtgctgc tgctgtgtga
2941 gggcctcagg catcccacgt gcaagctcca gaccctgcgg ttgggcatct gccggctggg
3001 ctctgccgcc tgtgagggtc tttctgtggt gctccaggcc aaccacaacc tccgggagct
3061 ggacttgagt ttcaacgacc tgggagactg gggcctgtgg ttgctggctg aggggctgca
3121 acatcccgcc tgcagactcc agaaactgtg gctggatagc tgtggcctca cagccaaggc
3181 ttgtgagaat ctttacttca ccctggggat caaccagacc ttgaccgacc tttacctgac
3241 caacaacgcc ctaggggaca caggtgtccg actgctttgc aagcggctga gccatcctgg
3301 ctgcaaactc cgagtcctct ggttatttgg gatggacctg aataaaatga cccacagtag
3361 gttggcagcg cttcgagtaa caaaacctta tttggacatt ggctgctgaa tggtcctatc
3421 tgctggctct cccctgagat ctggacagag gaagatggga gggtgctcat caccccccca
3481 gcataatgat cagcctcctt cctagagaca gactcatgca gattgagatc aaaagtccct
3541 ctgcttggga tcaaattaat gtttgacaga gctggccagg cgtggtggct catgtatgta
3601 atcctagcac ttcgagaggc cgaggcaggt ggatcacgag gtcaggagtt tgagattagc
3661 ctggccaaga tggtgaaacc ctgtctctac taaaaataaa aaaaaattag ccaggaaaaa
3721 aaaaaaaaaa a
//