LOCUS AY113698 1273 bp mRNA linear HUM 01-DEC-2002
DEFINITION Homo sapiens presenilin stabilization factor a (PSF) mRNA, complete
cds; alternatively spliced.
ACCESSION AY113698
VERSION AY113698.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1273)
AUTHORS Lee,H.-J. and Kim,T.-W.
TITLE Identification and characterization of presenilin stabilization
factor (PSF), an essential element for gamma-secretase activity
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1273)
AUTHORS Lee,H.-J. and Kim,T.-W.
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2002) Pathology, Columbia University, 630 West
168th Street P&S 14-511, New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..1273
/db_xref="H-InvDB:HIT000084462"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36.13-q31.3"
gene 1..1273
/gene="PSF"
CDS 58..801
/gene="PSF"
/note="polytopic transmembrane protein; CGI-78; PSFa"
/codon_start=1
/product="presenilin stabilization factor a"
/protein_id="AAM61955.1"
/translation="MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLV
SLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLA
SLSEDGRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTS
AFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIY
AVTVSMGLWAFITAGGSLRSIQRSLLCKD"
BASE COUNT 185 a 402 c 332 g 354 t
ORIGIN
1 cccctcccat ttgcctgtcc tggtcaggcc cccacccccc ttcccacctg accagccatg
61 ggggctgcgg tgtttttcgg ctgcactttc gtcgcgttcg gcccggcctt cgcgcttttc
121 ttgatcactg tggctgggga cccgcttcgc gttatcatcc tggtcgcagg ggcatttttc
181 tggctggtct ccctgctcct ggcctctgtg gtctggttca tcttggtcca tgtgaccgac
241 cggtcagatg cccggctcca gtacggcctc ctgatttttg gtgctgctgt ctctgtcctt
301 ctacaggagg tgttccgctt tgcctactac aagctgctta agaaggcaga tgaggggtta
361 gcatcgctga gtgaggacgg aagatcaccc atctccatcc gccagatggc ctatgtttct
421 ggtctctcct tcggtatcat cagtggtgtc ttctctgtta tcaatatttt ggctgatgca
481 cttgggccag gtgtggttgg gatccatgga gactcaccct attacttcct gacttcagcc
541 tttctgacag cagccattat cctgctccat accttttggg gagttgtgtt ctttgatgcc
601 tgtgagagga gacggtactg ggctttgggc ctggtggttg ggagtcacct actgacatcg
661 ggactgacat tcctgaaccc ctggtatgag gccagcctgc tgcccatcta tgcagtcact
721 gtttccatgg ggctctgggc cttcatcaca gctggagggt ccctccgaag tattcagcgc
781 agcctcttgt gtaaggactg actacctgga ctgatcgcct gacagatccc acctgcctgt
841 ccactgccca tgactgagcc cagccccagc ccgggtccat tgcccacatt ctctgtctcc
901 ttctcgtcgg tctaccccac tacctccagg gttttgcttt gtccttttgt gaccgttagt
961 ctctaagctt taccaggagc agcctgggtt cagccagtca gtgactggtg ggtttgaatc
1021 tgcacttatc cccaccacct ggggaccccc ttgttgtgtc caggactccc cctgtgtcag
1081 tgctctgctc tcaccctgcc caagactcac ctcccttccc ctctgcaggc cgacggcagg
1141 aggacagtcg ggtgatggtg tattctgccc tgcgcatccc acccgaggac tgagggaacc
1201 taggggggac ccctgggcct ggggtgccct cctgatgtcc tcgccctgta tttctccatc
1261 tccagttctg gac
//