LOCUS AY112983 3420 bp mRNA linear HUM 19-NOV-2003
DEFINITION Homo sapiens ubiquitin ligase NEDD4f (NEDD4L) mRNA, complete cds;
alternatively spliced.
ACCESSION AY112983
VERSION AY112983.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3420)
AUTHORS Qi,H., Grenier,J., Fournier,A. and Labrie,C.
TITLE Androgens differentially regulate the expression of NEDD4L
transcripts in LNCaP human prostate cancer cells
JOURNAL Mol. Cell. Endocrinol. 210 (1-2), 51-62 (2003)
PUBMED 14615060
REFERENCE 2 (bases 1 to 3420)
AUTHORS Qi,H. and Labrie,C.
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2002) Oncology and Molecular Endocrinology
Research Center, Laval University, 2705, Boul. Laurier, Quebec G1V
4G2, Canada
FEATURES Location/Qualifiers
source 1..3420
/db_xref="H-InvDB:HIT000250708"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21.31"
/cell_line="LNCaP"
gene 1..3420
/gene="NEDD4L"
/note="NEDD4-2"
CDS 553..3117
/gene="NEDD4L"
/note="alternatively spliced"
/codon_start=1
/product="ubiquitin ligase NEDD4f"
/protein_id="AAM76728.1"
/translation="MERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSD
QRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHR
PSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVN
IAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLR
SCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDA
KGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLS
APLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRP
FFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNS
KITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFE
ESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSA
TDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQIT
LNDMESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNEN
KREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVN
DWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGS
NGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD"
BASE COUNT 962 a 845 c 789 g 824 t
ORIGIN
1 gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc
61 tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc
121 gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa
181 cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggta acactcggga
241 gagtcccgta ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc
301 tttggagcca gtgatccgta tgtgaaactt tcattgtacg taccggatga gaatagagaa
361 cttgctttgg tccagacaaa aacaattaaa aagacactga acccaaaatg gaatgaagaa
421 ttttatttca gggtaaaccc atctaatcac agactcctat ttgaagtatt tgacgaaaat
481 agactgacac gagacgactt cctgggccag gtggacgtgc cccttagtca ccttccgaca
541 gaagatccaa ccatggagcg accctataca tttaaggact ttctcctcag accaagaagt
601 cataagtctc gagttaaggg atttttgcga ttgaaaatgg cctatatgcc aaaaaatgga
661 ggtcaagatg aagaaaacag tgaccagagg gatgacatgg agcatggatg ggaagttgtt
721 gactcaaatg actcggcttc tcagcaccaa gaggaacttc ctcctcctcc tctgcctccc
781 gggtgggaag aaaaagtgga caatttaggc cgaacttact atgtcaacca caacaaccgg
841 accactcagt ggcacagacc aagcctgatg gacgtgtcct cggagtcgga caataacatc
901 agacagatca accaggaggc agcacaccgg cgcttccgct cccgcaggca catcagcgaa
961 gacttggagc ccgagccctc ggagggcggg gatgtccccg agccttggga gaccatttca
1021 gaggaagtga atatcgctgg agactctctc ggtctggctc tgcccccacc accggcctcc
1081 ccaggatctc ggaccagccc tcaggagctg tcagaggaac taagcagaag gcttcagatc
1141 actccagact ccaatgggga acagttcagc tctttgattc aaagagaacc ctcctcaagg
1201 ttgaggtcat gcagtgtcac cgacgcagtt gcagaacagg gccatctacc accgcccagt
1261 gccccagctg ggagagcgcg ttcatcaact gtcacgggtg gtgaggaacc aacgccatca
1321 gtggcctatg tacataccac gccgggtctg ccttcaggct gggaagaaag aaaagatgct
1381 aaggggcgca catactatgt caatcataac aatcgaacca caacttggac tcgacctatc
1441 atgcagcttg cagaagatgg tgcgtccgga tcagccacaa acagtaacaa ccatctaatc
1501 gagcctcaga tccgccggcc tcgtagcctc agctcgccaa cagtaacttt atctgccccg
1561 ctggagggtg ccaaggactc acccgtacgt cgggctgtga aagacaccct ttccaaccca
1621 cagtccccac agccatcacc ttacaactcc cccaaaccac aacacaaagt cacacagagc
1681 ttcttgccac ccggctggga aatgaggata gcgccaaacg gccggccctt cttcattgat
1741 cataacacaa agactacaac ctgggaagat ccacgtttga aatttccagt acatatgcgg
1801 tcaaagacat ctttaaaccc caatgacctt ggcccccttc ctcctggctg ggaagaaaga
1861 attcacttgg atggccgaac gttttatatt gatcataata gcaaaattac tcagtgggaa
1921 gacccaagac tgcagaaccc agctattact ggtccggctg tcccttactc cagagaattt
1981 aagcagaaat atgactactt caggaagaaa ttaaagaaac ctgctgatat ccccaatagg
2041 tttgaaatga aacttcacag aaataacata tttgaagagt cctatcggag aattatgtcc
2101 gtgaaaagac cagatgtcct aaaagctaga ctgtggattg agtttgaatc agagaaaggt
2161 cttgactatg ggggtgtggc cagagaatgg ttcttcttac tgtccaaaga gatgttcaac
2221 ccctactacg gcctctttga gtactctgcc acggacaact acacccttca gatcaaccct
2281 aattcaggcc tctgtaatga ggatcatttg tcctacttca cttttattgg aagagttgct
2341 ggtctggccg tatttcatgg gaagctctta gatggtttct tcattagacc attttacaag
2401 atgatgttgg gaaagcagat aaccctgaat gacatggaat ctgtggatag tgaatattac
2461 aactctttga aatggatcct ggagaatgac cctactgagc tggacctcat gttctgcata
2521 gacgaagaaa actttggaca gacatatcaa gtggatttga agcccaatgg gtcagaaata
2581 atggtcacaa atgaaaacaa aagggaatat atcgacttag tcatccagtg gagatttgtg
2641 aacagggtcc agaagcagat gaacgccttc ttggagggat tcacagaact acttcctatt
2701 gatttgatta aaatttttga tgaaaatgag ctggagttgc tcatgtgcgg cctcggtgat
2761 gtggatgtga atgactggag acagcattct atttacaaga acggctactg cccaaaccac
2821 cccgtcattc agtggttctg gaaggctgtg ctactcatgg acgccgaaaa gcgtatccgg
2881 ttactgcagt ttgtcacagg gacatcgcga gtacctatga atggatttgc cgaactttat
2941 ggttccaatg gtcctcagct gtttacaata gagcaatggg gcagtcctga gaaactgccc
3001 agagctcaca catgctttaa tcgccttgac ttacctccat atgaaacctt tgaagattta
3061 cgagagaaac ttctcatggc cgtggaaaat gctcaaggat ttgaaggggt ggattaagca
3121 ccctgtgcct cgggggtggt tgttcttcaa gcaagttctg cttgcacttt tgcatttgcc
3181 taacagactt ttgcagaggc gatggcagag agcagctgca ggcatggtcc ctggagccga
3241 gccttcacca cgcactcgtc caagttcgga tgcgggaacc tggtcccagc ttgagttcct
3301 gcctttccca ccacaaatta tcaactggtt gatgtgtaca ctaattacat ttcaggagga
3361 cttaatgcta tttatgttgt gcctctgcag caaagccctt aataaatatt ttacatcctt
//