LOCUS AY102937 1928 bp mRNA linear HUM 23-JUL-2002
DEFINITION Homo sapiens SET domain-containing protein 8 (SET8) mRNA, complete
cds.
ACCESSION AY102937
VERSION AY102937.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1928)
AUTHORS Fang,J., Feng,Q., Ketel,C.S., Wang,H., Cao,R., Xia,L.,
Erdjument-Bromage,H., Tempst,P., Simon,J.A. and Zhang,Y.
TITLE Purification and functional characterization of SET8, a nucleosomal
histone H4-lysine 20-specific methyltransferase
JOURNAL Curr. Biol. 12 (13), 1086-1099 (2002)
PUBMED 12121615
REFERENCE 2 (bases 1 to 1928)
AUTHORS Fang,J., Feng,Q., Ketel,C.S., Wang,H., Cao,R., Xia,L.,
Erdjument-Bromage,H., Tempst,P., Simon,J.A. and Zhang,Y.
TITLE Direct Submission
JOURNAL Submitted (13-MAY-2002) Lineberger Comprehensive Cancer Center,
Department of Biochemistry and Biophysics, University of North
Carolina at Chapel Hill, 102 Mason Farm Road, Chapel Hill, NC
27599, USA
FEATURES Location/Qualifiers
source 1..1928
/db_xref="H-InvDB:HIT000084446"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1928
/gene="SET8"
CDS 14..1072
/gene="SET8"
/note="nucleosomal histone H4-K20 methyltransferase;
H4-K20-HMTase"
/codon_start=1
/product="SET domain-containing protein 8"
/protein_id="AAM47033.1"
/translation="MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDG
ENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAG
NAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKP
IKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGM
KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQ
YLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLY
DYGDRSKASIEAHPWLKH"
BASE COUNT 559 a 472 c 483 g 414 t
ORIGIN
1 gcagagtgga gccatggcta gaggcaggaa gatgtccaag ccccgcgcgg tggaggcggc
61 ggcggcggcg gcggcggtgg cagcgacggc cccgggcccg gagatggtgg agcggagggg
121 cccggggagg ccccgcaccg acggggagaa cgtatttacc gggcagtcaa agatctattc
181 ctacatgagc ccgaacaaat gctctggaat gcgtttcccc cttcaggaag agaactcagt
241 tacacatcac gaagtcaaat gccaggggaa accattagcc ggaatctaca ggaaacgaga
301 agagaaaaga aatgctggga acgcagtacg gagcgccatg aagtccgagg aacagaagat
361 caaagacgcc aggaaaggtc ccctggtacc ttttccaaac caaaaatctg aagcagcaga
421 acctccaaaa actccaccct catcttgtga ttccaccaat gcagccatcg ccaagcaagc
481 cctgaaaaag cccatcaagg gcaaacaggc cccccgaaaa aaagctcaag gaaaaacgca
541 acagaatcgc aaacttacgg atttctaccc tgtccgaagg agctccagga agagcaaagc
601 cgagctgcag tctgaagaaa ggaaaagaat agatgaattg attgaaagtg ggaaggaaga
661 aggaatgaaa attgacctca tcgatggcaa aggcaggggt gtgattgcca ccaagcagtt
721 ctcccggggt gactttgtgg tggaatacca cggggacctc atcgagatca ccgacgccaa
781 gaaacgggag gctctgtacg cacaggaccc ttccacgggc tgctacatgt actattttca
841 gtatctgagc aaaacctact gcgtggatgc aactagagag acaaatcgcc taggaagact
901 gatcaatcac agcaaatgtg ggaactgcca aaccaaactg cacgacatcg acggcgtacc
961 tcacctcatc ctcatcgcct cccgagacat cgcggctggg gaggagctcc tgtatgacta
1021 tggggaccgc agcaaggctt ccattgaagc ccacccgtgg ctgaagcatt aaccggtggg
1081 ccccgtgccc tccccgcccc actttccctt cttcaaagga caaagtgccc tcaaagggaa
1141 ttgaattttt tttttacaca cttaatctta gcggattact tcagatgttt ttaaaaagta
1201 tattaagatg ccttttcact gtagtattta aatatctgtt acaggtttcc aaggtggact
1261 tgaacagatg gccttatatt accaaaactt ttatattcta gttgtttttg tacttttttt
1321 gcatacaagc cgaacgtttg tgcttcccgt gcatgcagtc aaagactcag cacaggtttt
1381 agaggaaata gtcaaacatg aactaggaag ccaggtgagt ctcctttctc cagtggaaga
1441 gccgggacct tccccctgca cccccgacat ccagggacgg ggtgtgagga agacgctgcc
1501 tcccaatggc ctggacggga tgtttccaag ctcttgttcc cctaacgtct caacaggcgc
1561 tcactgaagt gtatgaatat tttttaaaaa ggtttttgca gtaagctagt cttcccctct
1621 gctttctcga aagcttactg agccctgggc cccaagcacg ggccgggcat agatttcctc
1681 ttccacaagc tgccgctttt ctgggcacct tgaagcatca gggcgtgaaa tcaaactaga
1741 tgtgggcagg gagagtgttg cttacctgcc ctgctggggc agggtttcct gaaactgggt
1801 taattcttta tagaaatgtg aacactgaat ttattttaaa aaataataat aaaaatttaa
1861 aaaaattaaa aataaaaaaa accacagaaa acaactttac atgtatatag gtcttgaagt
1921 gagtgaag
//