LOCUS AY102278 2389 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform B2 (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY102278
VERSION AY102278.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2389)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 2389)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
REFERENCE 3 (bases 1 to 2389)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
FEATURES Location/Qualifiers
source 1..2389
/db_xref="H-InvDB:HIT000084442"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
gene 1..2389
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..244
/gene="RTN4"
/gene_synonym="NOGO"
/experiment="experimental evidence, no additional details
recorded"
CDS 245..1423
/gene="RTN4"
/gene_synonym="NOGO"
/note="RTN4-B2; alternatively spliced"
/codon_start=1
/product="RTN4 isoform B2"
/protein_id="AAM64247.1"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAVVDLLYWRDIKKTG
VVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGAL
FNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
"
3'UTR 1424..2389
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 579 a 608 c 591 g 611 t
ORIGIN
1 gctggcctca ctcctagctc atctgggcgg cggcggcaac tggggacagg gcgggtggcg
61 catcaccggc gcggaggcag gaggagcagt ctcattgttc cgggagccgt caccacagta
121 ggtccctcgg ctcagtcggc ccagcccctc tcagtcctcc ccaaccccca caaccgcccg
181 cggctctgag acgcggcccc ggcggcggcg gcagcagctg cagcatcatc tccaccctcc
241 agccatggaa gacctggacc agtctcctct ggtctcgtcc tcggacagcc caccccggcc
301 gcagcccgcg ttcaagtacc agttcgtgag ggagcccgag gacgaggagg aagaagagga
361 ggaggaagag gaggacgagg acgaagacct ggaggagctg gaggtgctgg agaggaagcc
421 cgccgccggg ctgtccgcgg ccccagtgcc caccgcccct gccgccggcg cgcccctgat
481 ggacttcgga aatgacttcg tgccgccggc gccccgggga cccctgccgg ccgctccccc
541 cgtcgccccg gagcggcagc cgtcttggga cccgagcccg gtgtcgtcga ccgtgcccgc
601 gccatccccg ctgtctgctg ccgcagtctc gccctccaag ctccctgagg acgacgagcc
661 tccggcccgg cctccccctc ctcccccggc cagcgtgagc ccccaggcag agcccgtgtg
721 gaccccgcca gccccggctc ccgccgcgcc cccctccacc ccggccgcgc ccaagcgcag
781 gggctcctcg ggctcagtgg atgagaccct ttttgctctt cctgctgcat ctgagcctgt
841 gatacgctcc tctgcagttg ttgacctcct gtactggaga gacattaaga agactggagt
901 ggtgtttggt gccagcctat tcctgctgct ttcattgaca gtattcagca ttgtgagcgt
961 aacagcctac attgccttgg ccctgctctc tgtgaccatc agctttagga tatacaaggg
1021 tgtgatccaa gctatccaga aatcagatga aggccaccca ttcagggcat atctggaatc
1081 tgaagttgct atatctgagg agttggttca gaagtacagt aattctgctc ttggtcatgt
1141 gaactgcacg ataaaggaac tcaggcgcct cttcttagtt gatgatttag ttgattctct
1201 gaagtttgca gtgttgatgt gggtatttac ctatgttggt gccttgttta atggtctgac
1261 actactgatt ttggctctca tttcactctt cagtgttcct gttatttatg aacggcatca
1321 ggcacagata gatcattatc taggacttgc aaataagaat gttaaagatg ctatggctaa
1381 aatccaagca aaaatccctg gattgaagcg caaagctgaa tgaaaacgcc caaaataatt
1441 agtaggagtt catctttaaa ggggatattc atttgattat acgggggagg gtcagggaag
1501 aacgaacctt gacgttgcag tgcagtttca cagatcgttg ttagatcttt atttttagcc
1561 atgcactgtt gtgaggaaaa attacctgtc ttgactgcca tgtgttcatc atcttaagta
1621 ttgtaagctg ctatgtatgg atttaaaccg taatcatatc tttttcctat ctgaggcact
1681 ggtggaataa aaaacctgta tattttactt tgttgcagat agtcttgccg catcttggca
1741 agttgcagag atggtggagc tagaaaaaaa aaaaaaaaag cccttttcag tttgtgcact
1801 gtgtatggtc cgtgtagatt gatgcagatt ttctgaaatg aaatgtttgt ttagacgaga
1861 tcataccggt aaagcaggaa tgacaaagct tgcttttctg gtatgttcta ggtgtattgt
1921 gacttttact gttatattaa ttgccaatat aagtaaatat agattatata tgtatagtgt
1981 ttcacaaagc ttagaccttt accttccagc caccccacag tgcttgatat ttcagagtca
2041 gtcattggtt atacatgtgt agttccaaag cacataagct agaagaagaa atatttctag
2101 gagcactacc atctgttttc aacatgaaat gccacacaca tagaactcca acaacatcaa
2161 tttcattgca cagactgact gtagttaatt ttgtcacaga atctatggac tgaatctaat
2221 gcttccaaaa atgttgtttg tttgcaaata tcaaacattg ttatgcaaga aattattaat
2281 tacaaaatga agatttatac cattgtggtt taagctgtac tgaactaaat ctgtggaatg
2341 cattgtgaac tgtaaaagca aagtatcaat aaagcttata gacttaaaa
//