LOCUS AY102277 2332 bp mRNA linear HUM 23-SEP-2003
DEFINITION Homo sapiens RTN4 isoform B1 (RTN4) mRNA, complete cds;
alternatively spliced.
ACCESSION AY102277
VERSION AY102277.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2332)
AUTHORS Oertle,T., Huber,C., van der Putten,H. and Schwab,M.E.
TITLE Genomic structure and functional characterisation of the promoters
of human and mouse nogo/rtn4
JOURNAL J. Mol. Biol. 325 (2), 299-323 (2003)
PUBMED 12488097
REFERENCE 2 (bases 1 to 2332)
AUTHORS Oertle,T. and Schwab,M.E.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Brain Research Institute, University of
Zurich and ETH Zurich, Winterthurerstr.190, Zuerich 8057,
Switzerland
REFERENCE 3 (bases 1 to 2332)
AUTHORS Van der Putten,H.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) Nervous System Research, Novartis Pharma
Inc., Basel, Switzerland
FEATURES Location/Qualifiers
source 1..2332
/db_xref="H-InvDB:HIT000084441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
gene 1..2332
/gene="RTN4"
/gene_synonym="NOGO"
5'UTR 1..244
/gene="RTN4"
/gene_synonym="NOGO"
/experiment="experimental evidence, no additional details
recorded"
CDS 245..1366
/gene="RTN4"
/gene_synonym="NOGO"
/note="NOGO-B; RTN4-B1; alternatively spliced"
/codon_start=1
/product="RTN4 isoform B1"
/protein_id="AAM64246.1"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIV
SVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSA
LGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPV
IYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
3'UTR 1367..2332
/gene="RTN4"
/gene_synonym="NOGO"
BASE COUNT 571 a 590 c 579 g 592 t
ORIGIN
1 gctggcctca ctcctagctc atctgggcgg cggcggcaac tggggacagg gcgggtggcg
61 catcaccggc gcggaggcag gaggagcagt ctcattgttc cgggagccgt caccacagta
121 ggtccctcgg ctcagtcggc ccagcccctc tcagtcctcc ccaaccccca caaccgcccg
181 cggctctgag acgcggcccc ggcggcggcg gcagcagctg cagcatcatc tccaccctcc
241 agccatggaa gacctggacc agtctcctct ggtctcgtcc tcggacagcc caccccggcc
301 gcagcccgcg ttcaagtacc agttcgtgag ggagcccgag gacgaggagg aagaagagga
361 ggaggaagag gaggacgagg acgaagacct ggaggagctg gaggtgctgg agaggaagcc
421 cgccgccggg ctgtccgcgg ccccagtgcc caccgcccct gccgccggcg cgcccctgat
481 ggacttcgga aatgacttcg tgccgccggc gccccgggga cccctgccgg ccgctccccc
541 cgtcgccccg gagcggcagc cgtcttggga cccgagcccg gtgtcgtcga ccgtgcccgc
601 gccatccccg ctgtctgctg ccgcagtctc gccctccaag ctccctgagg acgacgagcc
661 tccggcccgg cctccccctc ctcccccggc cagcgtgagc ccccaggcag agcccgtgtg
721 gaccccgcca gccccggctc ccgccgcgcc cccctccacc ccggccgcgc ccaagcgcag
781 gggctcctcg ggctcagtgg ttgttgacct cctgtactgg agagacatta agaagactgg
841 agtggtgttt ggtgccagcc tattcctgct gctttcattg acagtattca gcattgtgag
901 cgtaacagcc tacattgcct tggccctgct ctctgtgacc atcagcttta ggatatacaa
961 gggtgtgatc caagctatcc agaaatcaga tgaaggccac ccattcaggg catatctgga
1021 atctgaagtt gctatatctg aggagttggt tcagaagtac agtaattctg ctcttggtca
1081 tgtgaactgc acgataaagg aactcaggcg cctcttctta gttgatgatt tagttgattc
1141 tctgaagttt gcagtgttga tgtgggtatt tacctatgtt ggtgccttgt ttaatggtct
1201 gacactactg attttggctc tcatttcact cttcagtgtt cctgttattt atgaacggca
1261 tcaggcacag atagatcatt atctaggact tgcaaataag aatgttaaag atgctatggc
1321 taaaatccaa gcaaaaatcc ctggattgaa gcgcaaagct gaatgaaaac gcccaaaata
1381 attagtagga gttcatcttt aaaggggata ttcatttgat tatacggggg agggtcaggg
1441 aagaacgaac cttgacgttg cagtgcagtt tcacagatcg ttgttagatc tttattttta
1501 gccatgcact gttgtgagga aaaattacct gtcttgactg ccatgtgttc atcatcttaa
1561 gtattgtaag ctgctatgta tggatttaaa ccgtaatcat atctttttcc tatctgaggc
1621 actggtggaa taaaaaacct gtatatttta ctttgttgca gatagtcttg ccgcatcttg
1681 gcaagttgca gagatggtgg agctagaaaa aaaaaaaaaa aagccctttt cagtttgtgc
1741 actgtgtatg gtccgtgtag attgatgcag attttctgaa atgaaatgtt tgtttagacg
1801 agatcatacc ggtaaagcag gaatgacaaa gcttgctttt ctggtatgtt ctaggtgtat
1861 tgtgactttt actgttatat taattgccaa tataagtaaa tatagattat atatgtatag
1921 tgtttcacaa agcttagacc tttaccttcc agccacccca cagtgcttga tatttcagag
1981 tcagtcattg gttatacatg tgtagttcca aagcacataa gctagaagaa gaaatatttc
2041 taggagcact accatctgtt ttcaacatga aatgccacac acatagaact ccaacaacat
2101 caatttcatt gcacagactg actgtagtta attttgtcac agaatctatg gactgaatct
2161 aatgcttcca aaaatgttgt ttgtttgcaa atatcaaaca ttgttatgca agaaattatt
2221 aattacaaaa tgaagattta taccattgtg gtttaagctg tactgaacta aatctgtgga
2281 atgcattgtg aactgtaaaa gcaaagtatc aataaagctt atagacttaa aa
//