LOCUS AY101765 5852 bp mRNA linear HUM 04-JUN-2004
DEFINITION Homo sapiens C3 and PZP-like alpha-2-macroglobulin domain
containing 8 (CPAMD8) mRNA, complete cds.
ACCESSION AY101765
VERSION AY101765.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5852)
AUTHORS Li,Z.F., Wu,X.H. and Engvall,E.
TITLE Identification and characterization of CPAMD8, a novel member of
the complement 3/alpha(2)-macroglobulin family with a C-terminal
Kazal domain
JOURNAL Genomics 83 (6), 1083-1093 (2004)
PUBMED 15177561
REFERENCE 2 (bases 1 to 5852)
AUTHORS Li,Z.F., Wu,X.H. and Engvall,E.
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2002) The Burnham Institute, 10901 N Torrey Pines
Rd, La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..5852
/db_xref="H-InvDB:HIT000084433"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13.1"
gene 1..5852
/gene="CPAMD8"
CDS 18..5675
/gene="CPAMD8"
/note="formerly Kazal-domain containing complement
3/a2-macroglobulin like protein; K-CAP; contains
Kazal-type serine protease inhibitor domain"
/codon_start=1
/product="C3 and PZP-like alpha-2-macroglobulin domain
containing 8"
/protein_id="AAM50084.1"
/translation="MSGALLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAG
VEEVISVTIFNSPREVTVQAQLVAQGEPVVQSQGAILDKGTIKLKVPTGLRGQALLKV
WGRGWQAEEGPLFHNQTSVTVDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVN
EKLEAYILDPRGSRMIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQGHAYNKS
FEVQKYVLPKFELLIDPPRYIQDLDACETGTVRARYTFGKPVAGALTINMTVNGVGYY
SHEVGRPVLRTTKILGSQDFDICVRDMIPADVPEHFRGRVSIWAMVTSVDGSQQVAFD
DSTPVQRQLVDIRYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDN
IYTSEVVSQRGLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWYSP
SQCYLQLQPPSHPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQR
SKRAAPALEKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRE
NGEGVADSLQFAVETFFENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVY
LLRSGFRLTPAQVFQELEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGIT
KDSGFAFTETGLVVMTDRVSLNHRQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTE
KRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSL
LKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKR
HVTKKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHAD
RRVPIGVDHVRRSVMVEAEGVPRAYTYSAFFCPSERVHISTPNKYEFQYVQRPLRLTR
FDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWISTSKMGEPVASAHTAKIL
SWDEFRTFWISWRGGLIQVGHGPEPSNESVIVAWTLPRPPEVQFIGFSTGWGSMGEFR
IWRKMEVDESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGE
QNMIHFAPNVFVLKYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERD
ASGSMWLTAFVLKSFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQ
GGIHGIVPLTAYVVVALLETGTASEEERGSTDKARHFLESAAPLAMDPYSCALTTYAL
TLLRSPAAPEALRKLRSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVE
MTAYALLTYTLLGDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAG
GINLTVSLASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVT
YNVPDPVAKPAFQLLVSLQEPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQE
YKVMLEVCTRWLHAGSSNMAVLEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRV
LFYFDEIPSRCLTCVRFRALRECVVGRTSALPVSVYDYYEPAFEATRFYNVSTHSPLA
RELCAGPACNEVERAPARGPGWFPGESGPAVAPEEGAAIARCGCDHDCGAQGNPVCGS
DGVVYASACRLREAACRQAAPLEPAPPSCCALEQRLPASSSSTYGDDLASVAPGPLQQ
DVKLNGAGLEVEDSDPEPEGEAEDRVTAGPRPPVSSGNLESSTQSASPFHRWGQTPAP
QRHSGRVVGAHRPGLLSPVFVYSPAFQSGGEEGLWMSNTCTLR"
BASE COUNT 1157 a 1795 c 1763 g 1137 t
ORIGIN
1 cccccaggag ccgaaaaatg agcggcgccc tgctctggcc gttgctcccg ctcctgctcc
61 tgctgctgtc ggcgcgggac ggcgtgcgcg ccgcgcagcc tcaggccccg ggttacttga
121 ttgcagctcc ctctgttttt cgcgcgggcg tggaggaagt catcagcgtg accatcttta
181 actctccaag ggaagtcacg gtccaggctc agctggtggc ccagggtgag ccggtggtgc
241 agagccaggg agccatcctg gataaaggga caatcaaact caaggtgccc acgggcctcc
301 ggggccaagc gcttctgaaa gtgtggggcc gcggctggca ggcggaggag gggcccctct
361 ttcacaacca gacctcggtg accgtggacg gccggggcgc ttctgtattc atccagacgg
421 acaagcctgt gtacagaccc cagcaccgag tgctcataag catcttcacc gtctctccaa
481 atctgaggcc tgtcaacgag aagctggaag cctacatcct ggacccccga ggctctcgga
541 tgatagagtg gagacactta aagccgttct gctgcggcat caccaacatg agcttcccct
601 tgtccgacca gcctgtgttg ggagaatggt tcatttttgt tgaaatgcaa ggccacgcgt
661 acaacaagtc ttttgaagtt cagaagtatg tgttgcccaa gtttgagctt ctgattgacc
721 cgccccggta tatccaagac ctggacgcct gtgagacagg cactgtgcgg gccaggtata
781 cctttgggaa acctgtggct ggtgccttaa cgatcaacat gactgttaat ggtgtagggt
841 actacagcca cgaggtggga cgccctgtcc tcagaacaac caagatcctc ggctcccagg
901 acttcgacat ctgcgtgagg gacatgatcc cagcggacgt ccctgagcac ttccggggca
961 gggtcagcat ctgggccatg gtgaccagtg tggacgggag ccagcaggtc gcgttcgatg
1021 actccacccc cgtgcagagg cagctggtgg acatccggta ctccaaggac acgaggaagc
1081 agttcaagcc gggcctggcc tacgtgggga aggtggagct atcctacccc gatggcagcc
1141 cagctgaggg ggtgacggtc cagattaagg cagagctgac accaaaggat aacatctaca
1201 ccagtgaagt tgtgtcccag cgtggactag tggggtttga aatcccctcc atccccacgt
1261 cagcccagca cgtgtggctg gagaccaagg tgatggcact gaacgggaag cccgtggggg
1321 ctcagtacct gcccagctac ctctccctcg gcagctggta ctcccccagc cagtgctacc
1381 tgcagctgca gccaccctcc cacccactgc aggttgggga agaagcctat ttttctgtga
1441 agtccacatg tccctgcaac tttaccctgt actacgaggt ggctgcacgg ggcaatattg
1501 tgctatcggg ccagcagcct gcccacacca cccagcagcg aagcaagcgg gcggcccctg
1561 ccctggagaa accgattcgt ttaacacacc tttctgagac agagccccca ccagccccag
1621 aagctgaggt cgacgtgtgt gtgacctctc ttcatctggc cgtgaccccc agcatggtcc
1681 cccttggtcg cctgctggtc ttctacgtca gggagaatgg agaaggggtc gccgacagcc
1741 ttcagtttgc agtcgagacc ttcttcgaaa accaggtttc agtgacgtat tcagcaaatg
1801 agacccaacc tggggaggtt gtcgacctgc ggatcagggc tgcaaggggc agctgtgtgt
1861 gcgtcgccgc agttgataag agtgtctacc tgctcaggtc tgggttccgg ctgactcctg
1921 cccaggtttt ccaggaactg gaagattatg atgtttctga ttcctttggc gtgtccaggg
1981 aggatggtcc tttttggtgg gctgggctga cggcacaacg acgccggcgc tcctctgtct
2041 tcccgtggcc ttggggcatc accaaggact ctgggtttgc cttcaccgaa acgggactgg
2101 tggtgatgac cgaccgagtg agcctgaacc accggcagga cggtggcctc tacaccgatg
2161 aggctgtccc cgctttccag ccccacacag ggagcctggt ggcagtggct ccttccaggc
2221 acccccccag aacagagaag agaaaaagga ctttcttccc cgaaacatgg atttggcatt
2281 gtctcaacat cagtgaccca tctggtgagg ggacactcag tgtgaaggtc ccggactcca
2341 tcaccagctg ggtgggtgag gccgtggccc tgtccacctc tcagggctta ggcatcgccg
2401 agccctccct gctgaagacc ttcaagccct tcttcgtgga cttcatgctc cccgctctca
2461 tcatccgtgg ggagcaggtc aagatcccgc tcagtgtcta caactacatg ggcacctgcg
2521 ctgaggtgta catgaagctc tcggttccca agggcatcca gtttgttggg catcctggca
2581 aacgccatgt gaccaagaag atgtgtgtgg cccccgggga ggctgagccc atctgggtcg
2641 ttctgtcctt cagcgacctg ggactcaaca acatcacggc caaagccctt gcttacggag
2701 acacaaattg ctgccgggat gggaggtcca gcaaacaccc tgaggagaat cacgccgaca
2761 ggagggtccc catcggggtg gatcacgtca ggcgcagtgt gatggttgag gcggaaggag
2821 tcccccgggc gtacacctac agcgcattct tctgtcccag tgagagagtc cacatctcca
2881 cccccaacaa gtatgagttc cagtatgtgc agcggccact gcgcctcacc cgctttgatg
2941 tggctgtgcg agctcacaat gatgcccgtg tggccttgtc ttctgggccc caggacacag
3001 caggcatgat cgagatcgtc ctgggggggc atcagaacac caggtcatgg atctccacca
3061 gcaagatggg agagcccgtg gccagtgcac acacggccaa gatcctctcc tgggatgaat
3121 tcagaacatt ctggatcagc tggcgtggtg gccttatcca ggttggccat ggtccagagc
3181 catccaatga gtctgtcatt gtggcctgga ccctcccgag gccaccagag gtccagttca
3241 ttggcttttc caccggctgg ggctccatgg gtgaattccg aatctggagg aagatggagg
3301 tggacgagag ctacagcgag gccttcaccc tgggggtccc acacggcgcc atccctgggt
3361 ctgagcgagc caccgcctcc atcatcgggg acgtcatggg gccaaccctg aaccacctca
3421 acaacctcct gcggctgccg tttggctgtg gagagcagaa catgatccac tttgcaccca
3481 acgtctttgt cttgaagtat cttcagaaaa cccagcagct cagccctgag gtggagagag
3541 agaccaccga ctacctagta caaggctacc agcgccagct gacctacaag cgccaggatg
3601 gctcctacag cgcgtttggg gagcgggacg catcggggag catgtggctc acagcctttg
3661 tcctgaagtc cttcgcacag gctcgcagct ttatcttcgt ggacccccgg gagctggctg
3721 ccgccaagag ctggatcatc cagcagcagc aggccgatgg ctccttcctg gccgtgggca
3781 gggtcctgaa caaggacatc cagggtggga tccacggcat tgtcccgctg acagcctacg
3841 tggtggttgc tctcctggaa acaggcacag cctcagagga ggagagaggc tccactgaca
3901 aagcgaggca cttcctggag tctgctgcgc ccctggccat ggacccttat agctgtgccc
3961 tgactaccta cgcgctgacc ctgctccgca gcccggcagc ccctgaggca ctgcgcaagc
4021 tccgtagcct ggccatcatg cgagatgggg tcacccactg gagcctgtca aattcctggg
4081 acgtggacaa gggcacattc ttgagcttca gtgacagggt ctctcagtca gtggtctcgg
4141 ccgaggtgga aatgacagcc tacgcccttc tgacctacac tctgctgggt gacgtggctg
4201 ccgccctgcc tgtggtgaag tggctgtccc agcagcgaaa tgcacttggg ggcttctcct
4261 ccactcagga cacctgcgtg gctctgcagg ccttggctga atatgccatc ttgtcctatg
4321 ctggaggcat caacctcact gtctccctgg cctccaccaa cctggactac caggaaacct
4381 tcgagctgca caggaccaac cagaaggttc tgcagacagc agcgatcccc agcctcccca
4441 cggggctgtt tgtgagtgcc aagggggacg gctgctgcct gatgcagatt gatgtcacct
4501 acaatgtgcc tgacccggtg gccaagccag ctttccagct gctcgtaagc ctccaggagc
4561 ctgaggccca gggacgcccg ccccccatgc ctgcctccgc agctgagggt tcccgaggag
4621 actggccccc agctgacgat gatgacccag cggccgatca gcatcaccag gaatacaagg
4681 tgatgctgga ggtgtgcacc aggtggctgc atgcagggtc ttccaatatg gctgtcctgg
4741 aggtgcccct gctgtcaggc ttccgggcag acatcgagag cctggagcag ctgctccttg
4801 acaagcacat ggggatgaag aggtatgaag tggctggacg ccgagtgctc ttctactttg
4861 atgagatccc cagccggtgc ctgacgtgcg tgcggttccg tgctctccgg gagtgcgtgg
4921 tgggcaggac gtcggcgctg ccagtctccg tgtacgacta ctacgaaccc gccttcgagg
4981 ccactcgctt ctacaacgtc agcacgcaca gcccactcgc ccgggaactg tgcgccggac
5041 ccgcgtgcaa cgaagtggag cgcgcccctg cccggggccc gggctggttc cccggcgagt
5101 cgggccctgc cgtggcccct gaggaggggg cggcgatcgc gcgatgcggc tgcgaccacg
5161 actgcggcgc ccaggggaac ccggtgtgcg gctccgacgg ggtggtctac gccagcgcct
5221 gccgcctgcg ggaggccgcc tgccgccagg ccgcgcccct ggagcccgcg cctcccagct
5281 gctgcgccct cgagcagcgg ctgccggcct cgtcgtcctc cacctacggg gatgacctgg
5341 cttctgtggc cccggggcct ttacagcagg acgtgaagct gaatggagcc ggccttgagg
5401 tggaggactc agaccctgag cctgaagggg aggcggagga cagggtcaca gccgggcctc
5461 ggcctcctgt gagcagcggg aacctggaaa gcagcaccca gagcgccagc ccgttccaca
5521 gatggggcca gactccggcc cctcagagac atagtggccg ggtggtgggg gcccacaggc
5581 cagggcttct gagccctgtc ttcgtctaca gcccagcctt tcagagtggt ggggaggagg
5641 gtttatggat gtcaaacacc tgcaccttga gataatccta caaccacatg cagttgtggg
5701 accgcagttt ggtcctgggg accattcata cccacacacc cagcttgtgc ctgtggttaa
5761 catctcagaa aactctggta aatgatcact ccaggatatt gacacgaata cacgttactg
5821 atcttactca catgttaaaa aaaaaaaaaa aa
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