LOCUS AY101176 4279 bp mRNA linear HUM 21-DEC-2002
DEFINITION Homo sapiens extracellular sulfatase SULF-2 mRNA, complete cds.
ACCESSION AY101176
VERSION AY101176.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4279)
AUTHORS Morimoto-Tomita,M., Uchimura,K., Werb,Z., Hemmerich,S. and
Rosen,S.D.
TITLE Cloning and characterization of two extracellular heparin-degrading
endosulfatases in mice and humans
JOURNAL J. Biol. Chem. 277 (51), 49175-49185 (2002)
PUBMED 12368295
REFERENCE 2 (bases 1 to 4279)
AUTHORS Morimoto-Tomita,M., Werb,Z., Hemmerich,S. and Rosen,S.D.
TITLE Direct Submission
JOURNAL Submitted (30-APR-2002) Biology, Thios Pharmaceuticals Inc., 747
Fifty Second Street, Oakland, CA 94609, USA
FEATURES Location/Qualifiers
source 1..4279
/db_xref="H-InvDB:HIT000084420"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q13.12"
/tissue_type="lung"
CDS 670..3282
/codon_start=1
/product="extracellular sulfatase SULF-2"
/protein_id="AAM76861.1"
/translation="MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRP
NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVH
NHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEW
VGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLM
VISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFT
NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMP
YEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDT
ERPVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDAQEENFLPKYQRVKDLCQRAE
YQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLGGSRALSNLVPKYYGQGSEACTCDS
GDYKLSLAGRRKKLFKKKYKASYVRSRSIRSVAIEVDGRVYHVGLGDAAQPRNLTKRH
WPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAW
KDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHRGSSL
HPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPF
WTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTL
DRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRP
SSKSLGQLWEGWEG"
regulatory 3944..3948
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1186 a 1143 c 1105 g 845 t
ORIGIN
1 gggccatttc tggacaacag ctgctatttt cacttgagcc caagttaatt tctcggggag
61 ttctcgggcg cgcacaggca gctcggtttg ccctgcgatt gagctgcggg tcgcggccgg
121 cgccggcctc tccaatggca aatgtgtgtg gctggaggcg agcgcgaggc tttcggcaaa
181 ggcagtcgag tgtttgcaga ccggggcgag tcctgtgaaa gcagataaaa gaaaacattt
241 attaacgtgt cattacgagg ggagcgcccg gccggggctg tcgcactccc cgcggaacat
301 ttggctccct ccagctccta gagaggagaa gaagaaagcg gaaaagaggc agattcacgt
361 cgtttccagc caagtggacc tgatcgatgg ccctcctgaa tttatcacga tatttgattt
421 attagcgatg ccccctggtt tgtgtgttac gcacacacac gtgcacacaa ggctctggct
481 cgcttccctc cctcgtttcc agctcctggg cgaatcccac atctgtttca actctccgcc
541 gagggcgagc aggagcgaga gtgtgtcgaa tctgcgagtg aagagggacg agggaaaaga
601 aacaaagcca cagacgcaac ttgagactcc cgcatcccaa aagaagcacc agatcagcaa
661 aaaaagaaga tgggcccccc gagcctcgtg ctgtgcttgc tgtccgcaac tgtgttctcc
721 ctgctgggtg gaagctcggc cttcctgtcg caccaccgcc tgaaaggcag gtttcagagg
781 gaccgcagga acatccgccc caacatcatc ctggtgctga cggacgacca ggatgtggag
841 ctgggttcca tgcaggtgat gaacaagacc cggcgcatca tggagcaggg cggggcgcac
901 ttcatcaacg ccttcgtgac cacacccatg tgctgcccct cacgctcctc catcctcacc
961 ggcaagtacg tccacaacca caacacctac accaacaatg agaactgctc ctcgccctcc
1021 tggcaggcac agcacgagag ccgcaccttt gccgtgtacc tcaatagcac tggctaccgg
1081 acagctttct tcgggaagta tcttaatgaa tacaacggct cctacgtgcc acccggctgg
1141 aaggagtggg tcggactcct taaaaactcc cgcttttata actacacgct gtgtcggaac
1201 ggggtgaaag agaagcacgg ctccgactac tccaaggatt acctcacaga cctcatcacc
1261 aatgacagcg tgagcttctt ccgcacgtcc aagaagatgt acccgcacag gccagtcctc
1321 atggtcatca gccatgcagc cccccacggc cctgaggatt cagccccaca atattcacgc
1381 ctcttcccaa acgcatctca gcacatcacg ccgagctaca actacgcgcc caacccggac
1441 aaacactgga tcatgcgcta cacggggccc atgaagccca tccacatgga attcaccaac
1501 atgctccagc ggaagcgctt gcagaccctc atgtcggtgg acgactccat ggagacgatt
1561 tacaacatgc tggttgagac gggcgagctg gacaacacgt acatcgtata caccgccgac
1621 cacggttacc acatcggcca gtttggcctg gtgaaaggga aatccatgcc atatgagttt
1681 gacatcaggg tcccgttcta cgtgaggggc cccaacgtgg aagccggctg tctgaatccc
1741 cacatcgtcc tcaacattga cctggccccc accatcctgg acattgcagg cctggacata
1801 cctgcggata tggacgggaa atccatcctc aagctgctgg acacggagcg gccggtgaat
1861 cggtttcact tgaaaaagaa gatgagggtc tggcgggact ccttcttggt ggagagaggc
1921 aagctgctac acaagagaga caatgacaag gtggacgccc aggaggagaa ctttctgccc
1981 aagtaccagc gtgtgaagga cctgtgtcag cgtgctgagt accagacggc gtgtgagcag
2041 ctgggacaga agtggcagtg tgtggaggac gccacgggga agctgaagct gcataagtgc
2101 aagggcccca tgcggctggg cggcagcaga gccctctcca acctcgtgcc caagtactac
2161 gggcagggca gcgaggcctg cacctgtgac agcggggact acaagctcag cctggccgga
2221 cgccggaaaa aactcttcaa gaagaagtac aaggccagct atgtccgcag tcgctccatc
2281 cgctcagtgg ccatcgaggt ggacggcagg gtgtaccacg taggcctggg tgatgccgcc
2341 cagccccgaa acctcaccaa gcggcactgg ccaggggccc ctgaggacca agatgacaag
2401 gatggtgggg acttcagtgg cactggaggc cttcccgact actcagccgc caaccccatt
2461 aaagtgacac atcggtgcta catcctagag aacgacacag tccagtgtga cctggacctg
2521 tacaagtccc tgcaggcctg gaaagaccac aagctgcaca tcgaccacga gattgaaacc
2581 ctgcagaaca aaattaagaa cctgagggaa gtccgaggtc acctgaagaa aaagcggcca
2641 gaagaatgtg actgtcacaa aatcagctac cacacccagc acaaaggccg cctcaagcac
2701 agaggctcca gtctgcatcc tttcaggaag ggcctgcaag agaaggacaa ggtgtggctg
2761 ttgcgggagc agaagcgcaa gaagaaactc cgcaagctgc tcaagcgcct gcagaacaac
2821 gacacgtgca gcatgccagg cctcacgtgc ttcacccacg acaaccagca ctggcagacg
2881 gcgcctttct ggacactggg gcctttctgt gcctgcacca gcgccaacaa taacacgtac
2941 tggtgcatga ggaccatcaa tgagactcac aatttcctct tctgtgaatt tgcaactggc
3001 ttcctagagt actttgatct caacacagac ccctaccagc tgatgaatgc agtgaacaca
3061 ctggacaggg atgtcctcaa ccagctacac gtacagctca tggagctgag gagctgcaag
3121 ggttacaagc agtgtaaccc ccggactcga aacatggacc tgggacttaa agatggagga
3181 agctatgagc aatacaggca gtttcagcgt cgaaagtggc cagaaatgaa gagaccttct
3241 tccaaatcac tgggacaact gtgggaaggc tgggaaggtt aagaaacaac agaggtggac
3301 ctccaaaaac atagaggcat cacctgactg cacaggcaat gaaaaaccat gtgggtgatt
3361 tccagcagac ctgtgctatt ggccaggagg cctgagaaag caagcacgca ctctcagtca
3421 acatgacaga ttctggagga taaccagcag gagcagagat aacttcagga agtccatttt
3481 tgcccctgct tttgctttgg attatacctc accagctgca caaaatgcat tttttcgtat
3541 caaaaagtca ccactaaccc tcccccagaa gctcacaaag gaaaacggag agagcgagcg
3601 agagagattt ccttggaaat ttctcccaag ggcgaaagtc attggaattt ttaaatcata
3661 ggggaaaagc agtcctgttc taaatcctct tattcttttg gtttgtcaca aagaaggaac
3721 taagaagcag gacagaggca acgtggagag gctgaaaaca gtgcagagac gtttgacaat
3781 gagtcagtag cacaaaagag atgacattta cctagcatat aaaccctggt tgcctctgaa
3841 gaaactgcct tcattgtata tatgtgacta tttacatgta atcaacatgg gaacttttag
3901 gggaacctaa taagaaatcc caattttcag gagtggtggt gtcaataaac gctctgtggc
3961 cagtgtaaaa gaaaaaaaaa aaaaattgtg gacatttctg ttcctgtcca gataccattt
4021 ctcctagtat ttctttgtta tgtcccagaa ctgatgtttt ttttttaagg tactgaaaag
4081 aaatgaagtt gatgtatgtc ccaagttttg atgaaactgt atttgtaaaa aaaattttgt
4141 agtttaagta ttgtcataca gtgttcaaaa ccccagccaa tgaccagcag ttggtatgaa
4201 gaacctttga cattttgtaa aaggccattt cttggggaaa aaaaaaaaaa aaaaaaaaaa
4261 aaaaaaaaaa aaaaaaaaa
//