LOCUS AY091855 2020 bp mRNA linear HUM 22-MAY-2002
DEFINITION Homo sapiens steroid and xenobiotic sensing nuclear receptor SXR
(NR1I2) mRNA, complete cds.
ACCESSION AY091855
VERSION AY091855.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2020)
AUTHORS Blumberg,B., Sabbagh,W. Jr., Juguilon,H., Bolado,J. Jr., van
Meter,C.M., Ong,E.S. and Evans,R.M.
TITLE SXR, a novel steroid and xenobiotic-sensing nuclear receptor
JOURNAL Genes Dev. 12 (20), 3195-3205 (1998)
PUBMED 9784494
REFERENCE 2 (bases 1 to 2020)
AUTHORS Blumberg,B.
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2002) Dev. and Cell Biology, University of
California, Irvine, 5205 McGaugh Hall, Irvine, CA 92697-2300, USA
FEATURES Location/Qualifiers
source 1..2020
/db_xref="H-InvDB:HIT000084353"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q13.2"
gene 1..2020
/gene="NR1I2"
/gene_synonym="SXR"
CDS 583..1887
/gene="NR1I2"
/gene_synonym="SXR"
/codon_start=1
/product="steroid and xenobiotic sensing nuclear receptor
SXR"
/protein_id="AAM26736.1"
/translation="MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVC
GDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKC
LESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK
TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGE
DGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLL
KGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQ
LHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLK
IMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS"
BASE COUNT 509 a 523 c 571 g 417 t
ORIGIN
1 ggcacgagga gatctaggtt caaattaatg ttgcccctag tggtaaagga cagagaccct
61 cagactgatg aaatgcgctc agaattactt agacaaagcg gatatttgcc actctcttcc
121 ccttttcctg tgtttttgta gtgaagagac ctgaaagaaa aaagtaggga gaacataatg
181 agaacaaata cggtaatctc ttcatttgct agttcaagtg ctggacttgg gacttaggag
241 gggcaatgga gccgcttagt gcctacatct gacttggact gaaatatagg tgagagacaa
301 gattgtctca tatccgggga aatcataacc tatgactagg acgggaagag gaagcactgc
361 ctttacttca gtgggaatct cggcctcagc ctgcaagcca agtgttcaca gtgagaaaag
421 caagagaata agctaatact cctgtcctga acaaggcagc ggctccttgg taaagctact
481 ccttgatcga tcctttgcac cggattgttc aaagtggacc ccaggggaga agtcggagca
541 aagaacttac caccaagcag tccaagaggc ccagaagcaa acctggaggt gagacccaaa
601 gaaagctgga accatgctga ctttgtacac tgtgaggaca cagagtctgt tcctggaaag
661 cccagtgtca acgcagatga ggaagtcgga ggtccccaaa tctgccgtgt atgtggggac
721 aaggccactg gctatcactt caatgtcatg acatgtgaag gatgcaaggg ctttttcagg
781 agggccatga aacgcaacgc ccggctgagg tgccccttcc ggaagggcgc ctgcgagatc
841 acccggaaga cccggcgaca gtgccaggcc tgccgcctgc gcaagtgcct ggagagcggc
901 atgaagaagg agatgatcat gtccgacgag gccgtggagg agaggcgggc cttgatcaag
961 cggaagaaaa gtgaacggac agggactcag ccactgggag tgcaggggct gacagaggag
1021 cagcggatga tgatcaggga gctgatggac gctcagatga aaacctttga cactaccttc
1081 tcccatttca agaatttccg gctgccaggg gtgcttagca gtggctgcga gttgccagag
1141 tctctgcagg ccccatcgag ggaagaagct gccaagtgga gccaggtccg gaaagatctg
1201 tgctctttga aggtctctct gcagctgcgg ggggaggatg gcagtgtctg gaactacaaa
1261 cccccagccg acagtggcgg gaaagagatc ttctccctgc tgccccacat ggctgacatg
1321 tcaacctaca tgttcaaagg catcatcagc tttgccaaag tcatctccta cttcagggac
1381 ttgcccatcg aggaccagat ctccctgctg aagggggccg ctttcgagct gtgtcaactg
1441 agattcaaca cagtgttcaa cgcggagact ggaacctggg agtgtggccg gctgtcctac
1501 tgcttggaag acactgcagg tggcttccag caacttctac tggagcccat gctgaaattc
1561 cactacatgc tgaagaagct gcagctgcat gaggaggagt atgtgctgat gcaggccatc
1621 tccctcttct ccccagaccg cccaggtgtg ctgcagcacc gcgtggtgga ccagctgcag
1681 gagcaattcg ccattactct gaagtcctac attgaatgca atcggcccca gcctgctcat
1741 aggttcttgt tcctgaagat catggctatg ctcaccgagc tccgcagcat caatgctcag
1801 cacacccagc ggctgctgcg catccaggac atacacccct ttgctacgcc cctcatgcag
1861 gagttgttcg gtatcacagg tagctgagtg gctgtccttg ggtgacacct ccgagaggta
1921 gttagaccca gagccctctg agtcgccact cccgggccaa gacagatgga cactgccaag
1981 agccgacaat gccctgctgg cctgtctccc tagggaattc
//