LOCUS AY082340 5403 bp mRNA linear HUM 02-APR-2002
DEFINITION Homo sapiens putative protein kinase WNK3 (PRKWNK3) mRNA, complete
cds.
ACCESSION AY082340
VERSION AY082340.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5403)
AUTHORS Holden,S.T. and Raymond,F.L.
TITLE Full length coding sequence for human WNK3 determined from Clontech
Marathon cDNA (fetal brain)
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5403)
AUTHORS Holden,S.T. and Raymond,F.L.
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) Department of Medical Genetics, Cambridge
Institute for Medical Research, Addenbrooke's Hospital Site,
Cambridge, Cambridgeshire CB2 2XY, UK
FEATURES Location/Qualifiers
source 1..5403
/db_xref="H-InvDB:HIT000084253"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp11.2"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..5403
/gene="PRKWNK3"
CDS 1..5403
/gene="PRKWNK3"
/codon_start=1
/product="putative protein kinase WNK3"
/protein_id="AAL99253.1"
/translation="MATDSGDPANTEDSEKPDGISFENRVPQVAATLTVEARLKEKNS
TFSASGETVERKRFFRKSVEMTEDDKVAESSPKDERIKAAMNIPRVDKLPSNVLRGGQ
EVKYEQCSKSTSEISKDCFKEKNEKEMEEEAEMKAVATSPSGRFLKFDIELGRGAFKT
VYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILK
GKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDL
KCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAF
GMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSE
RLSIRDLLNHAFFAEDTGLRVELAEEDDCSNSSLALRLWVEDPKKLKGKHKDNEAIEF
SFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVTPIKKTREKKPAGCLEERRD
SQCKSMGNVFPQPQNTTLPLAPAQQTGAECEETEVDQHVRQQLLQRKPQQHCSSVTGD
NLSEAGAASVIHSDTSSQPSVAYSSNQTMGSQMVSNIPQAEVNVPGQIYSSQQLVGHY
QQVSGLQKHSKLTQPQILPLVQGQSTVLPVHVLGPTVVSQPQVSPLTVQKVPQIKPVS
QPVGAEQQAALLKPDLVRSLNQDVATTKENVSSPDNPSGNGKQDRIKQRRASCPRPEK
GTKFQLTVLQVSTSGDNMVECQLETHNNKMVTFKFDVDGDAPEDIADYMVEDNFVLES
EKEKFVEELRAIVGQAQEILHVHFATERATGVDSITVDSNSSQTGSSEQVQINSTSTQ
TSNESAPQSSPVGRWRFCINQTIRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEI
SRDTLLTIENNPCHRALFTSKSEHKDVVDGKISECASVETKQPAILYQVEDNRQIMAP
VTNSSSYSTTSVRAVPAECEGLTKQASIFIPVYPCHQTASQADALMSHPGESTQTSGN
SLTTLAFDQKPQTLSVQQPAMDAEFISQEGETTVNTEASSPKTVIPTQTPGLEPTTLQ
PTTVLESDGERPPKLEFADNRIKTLDEKLRNLLYQEHSISSIYPESQKDTQSIDSPFS
SSAEDTLSCPVTEVIAISHCGIKDSPVQSPNFQQTGSKLLSNVAASQPANISVFKRDL
NVITSVPSELCLHEMSSDASLPGDPEAYPAAVSSGGAIHLQTGGGYFGLSFTCPSLKN
PISKKSWTRKLKSWAYRLRQSTSFFKRSKVRQVETEEMRSAIAPDPIPLTRESTADTR
ALNRCKAMSGSFQRGRFQVITIPQQQSAKMTSFGIEHISVFSETNHSSEEAFIKTAKS
QLVEIEPATQNPKTSFSYEKLQALQETCKENKGVPKQGDNFLSFSAACETDVSSVTPE
KEFEETSATGSSMQSGSELLLKEREILTAGKQPSSDSEFSASLAGSGKSVAKTGPESN
QCLPHHEEQAYAQTQSSLFYSPSSPMSSDDESEIEDEDLKVELQRLREKHIQEVVNLQ
TQQNKELQELYERLRSIKDSKTQSTEIPLPPASPRRPRSFKSKLRSRPQSLTHVDNGI
VATGKSCLINELENPLCVESNAASCQQSPASKKGMFTDDLHKLVDDWTKEAVGNSLIK
PSLNQLKQSQHKLETENWNKVSENTPSTMGYTSTWISSLSQIRGAVPTSLPQGLSLPS
FPGPLSSYGMPHVCQYNAVAGAGYPVQWVGISGTTQQSVVIPAQSGGPFQPGMNMQAF
PTSSVQNPATIPPGPK"
BASE COUNT 1726 a 1171 c 1178 g 1328 t
ORIGIN
1 atggccactg attcagggga tccagccaac acagaagatt ctgagaaacc tgatggaatt
61 tcatttgaaa acagagttcc ccaggtcgct gcaactttga cagtagaagc tagactaaag
121 gagaaaaaca gtaccttctc tgcttctggg gaaactgtag aaaggaagag atttttccga
181 aagagtgttg aaatgacgga agatgacaaa gttgccgaat catcccccaa agatgagaga
241 attaaggctg caatgaatat tccaagagta gataagcttc cttcaaatgt gttgagaggt
301 ggacaagaag ttaaatatga acagtgttca aagtcaacct cagaaatctc aaaagattgt
361 ttcaaggaga aaaatgaaaa ggaaatggaa gaagaagcag aaatgaaggc tgtagctact
421 tctcctagtg gcagattcct gaaatttgac atagaactag gaagaggagc atttaaaaca
481 gtatataaag gactggacac tgaaacatgg gttgaggttg cttggtgtga gctgcaggac
541 cgaaagttaa ccaaagctga gcagcaaaga ttcaaggaag aagcagagat gttgaagggt
601 ctccagcacc ccaatatagt tcgattttat gattcctggg aatctatatt aaaaggaaag
661 aaatgtattg tattagtgac tgaactaatg acatctggga ccttaaagac gtacttaaaa
721 cgatttaaag tcatgaaacc aaaggtctta aggagctggt gcaggcaaat tttaaagggg
781 ttgcagttct tgcacactag gactcctcct attattcacc gggatctgaa gtgtgacaat
841 attttcatca cgggacccac tggatctgtg aagattggtg atctaggatt agccacctta
901 atgcgtacct catttgctaa gagtgtcatt ggaactcctg agtttatggc tccagagatg
961 tatgaagaac actatgatga atccgtagat gtttatgctt ttggaatgtg tatgctggaa
1021 atggccacat cggagtatcc ttattctgag tgtcagaatg cagctcaaat ataccggaaa
1081 gtaactagtg gcataaaacc agccagcttc aataaagtca ctgatcctga agtcaaagaa
1141 atcattgaag gatgtattcg tcaaaacaaa tctgaaaggt tgtctatcag ggacctatta
1201 aaccatgcat tttttgctga ggatacagga ctgagggtgg agttagcaga agaagatgat
1261 tgctcaaatt catcccttgc tttaagactc tgggttgaag accctaaaaa attgaaaggc
1321 aaacacaaag acaatgaagc tattgaattt agtttcaact tagaaacaga tacacctgag
1381 gaagtagcat atgaaatggt caagtctggg ttcttccatg aaagtgattc caaagctgtt
1441 gctaaatcca ttagagaccg ggtgacgcca ataaagaaga caagagagaa gaagcctgct
1501 ggctgtttgg aagaacgcag ggattctcag tgcaagtcta tggggaatgt attccctcag
1561 ccccagaata caactttacc ccttgctccc gctcagcaaa ctggggctga atgtgaagaa
1621 actgaagttg atcaacatgt tagacaacag cttctacaaa gaaaaccaca gcagcactgc
1681 tcctctgtta caggtgacaa tttgtctgag gcaggagctg catcagttat acattcagat
1741 acttcaagtc agcccagtgt agcctattcc tcaaatcaaa cgatgggctc tcaaatggtt
1801 tctaatatcc cgcaggctga agtaaatgtt ccagggcaaa tttattcatc tcagcaacta
1861 gtaggacatt accagcaagt ttcagggtta cagaagcatt caaagctgac tcagccgcag
1921 attttgcctt tggttcaagg tcagtccact gttttacctg tacatgtcct tggaccgaca
1981 gttgtttcac aaccccaggt ttccccatta actgttcaga aggtcccaca gataaagcct
2041 gtatcccaac cagttggagc tgaacaacaa gcagctcttc taaaaccaga tttagttcga
2101 agcttgaatc aagatgtggc aactacgaag gaaaacgtca gtagccctga taacccaagt
2161 ggaaatggca aacaggatcg gatcaaacag agaagagctt cctgtccccg accagagaag
2221 gggactaaat ttcagcttac cgtccttcag gtatcaacct ctggagataa catggtagag
2281 tgtcagctgg agacacacaa caacaagatg gtcaccttca agtttgatgt tgatggtgat
2341 gcgccagagg atattgcaga ctatatggtt gaagataact ttgtgctgga aagtgagaaa
2401 gaaaaatttg tagaagaatt gagagctatt gtaggtcaag cccaggagat ccttcatgtc
2461 cactttgcca cagaaagagc cactggagtt gattctatta ctgtggactc caacagtagc
2521 cagacagggt catctgaaca agtacagata aattctacat ctactcaaac cagcaatgaa
2581 tctgctcctc agtcatcccc agttggtcgg tggcgattct gtatcaatca gacgataaga
2641 aaccgtgaga ctcagtctcc tccttctctt cagcattcca tgtctgcggt tcctggccga
2701 catccacttc ctagtccaaa aaacacaagt aataaggaaa tatcacggga cacattgctc
2761 actatagaaa ataatccatg ccaccgtgca cttttcacct ccaaatcaga acacaaggat
2821 gtggttgatg gtaagatttc tgaatgtgct agtgtagaaa ccaagcagcc agctatactt
2881 tatcaagtgg aagataacag gcagataatg gcaccagtta ctaatagttc cagttactct
2941 actacttcag ttcgtgcagt tccagctgaa tgtgagggac tcaccaaaca agcaagcata
3001 ttcatacctg tgtatccatg tcaccaaact gccagtcagg ctgatgcact tatgtcccat
3061 cctggcgaat caactcagac ttctggtaac tctcttacaa ctctggcatt tgatcaaaag
3121 cctcaaacct tatcagtaca gcagccagct atggatgcag agtttatttc tcaagaagga
3181 gaaactacag tgaacactga agcaagttct cctaagacag tcattcccac tcagacccct
3241 ggccttgaac caactaccct tcaacccact actgtcctgg aatcagatgg agaaagacct
3301 ccaaaactgg agtttgcaga caaccgaatt aaaactctgg atgaaaaatt aagaaacttg
3361 ctctatcagg agcacagcat ctctagcatc tatcccgaga gtcagaagga tacccaaagc
3421 atagactctc cattttcttc ctctgctgaa gataccctct cctgtccagt gacagaagtc
3481 atagccatca gtcactgtgg aattaaagat agccctgtac aatcccctaa tttccaacag
3541 acaggctcta agcttctgtc caatgtggct gcaagtcagc ctgctaatat atcagtgttc
3601 aaaagggacc tgaatgtgat aacttctgta cccagcgaat tgtgtttaca tgagatgtcc
3661 tcagatgctt cacttccagg ggatccagag gcctatcctg ctgctgtgtc aagcggtgga
3721 gccattcatc tgcagacagg aggtggatat tttggcctaa gctttacttg tcctagtctc
3781 aaaaatccta ttagcaagaa atcctggact cgcaaattaa aaagctgggc atacaggcta
3841 cggcagtcaa ccagcttttt caagagatca aaagtccgtc aagtggaaac agaagagatg
3901 agatcagcaa ttgctcctga tcccattcct ctgacacggg agtccacagc tgatactagg
3961 gctttgaata gatgtaaagc gatgagtgga tcatttcagc ggggtcggtt ccaggtgatt
4021 acaattcctc agcagcagtc agcaaaaatg acatcttttg gaatagaaca catatcagtg
4081 ttcagtgaga caaaccattc tagtgaagaa gcctttatta aaacagcaaa gtctcagttg
4141 gtagaaatag aacctgccac acaaaatcca aaaacttcgt tttcttatga gaagttacaa
4201 gctcttcagg aaacctgtaa agaaaataaa ggagttccca aacaaggtga caacttctta
4261 tctttcagcg cagcttgtga gactgatgta tcttcagtga ccccagaaaa ggaatttgaa
4321 gaaacttcag ccacaggaag tagcatgcag tctggatctg aactgttgct taaagagaga
4381 gagatattga ctgctgggaa acagcctagc tctgatagtg aattttcagc cagtcttgct
4441 ggcagtggaa agtcagtggc aaagactggt ccagagagta atcagtgctt accacaccac
4501 gaagaacaag cttatgctca aacacagagt tcactcttct attcgccatc ttccccaatg
4561 agcagtgatg atgaatcaga aatagaggat gaggacttga aggtggagct tcaaagatta
4621 cgagaaaaac acattcagga ggtggtaaat cttcaaaccc agcagaataa ggagctgcag
4681 gagctctatg aacgccttcg gtcaattaaa gatagcaaaa cccaatctac tgagattcct
4741 ttgccacctg catcaccacg tcgaccaaga tctttcaaaa gcaaacttcg aagccgcccc
4801 cagtccttga cacatgtgga caatggcata gttgctacag ggaaaagctg ccttataaat
4861 gagttggaaa atccactgtg tgtggagagt aatgcagcat catgccaaca gtctccagcc
4921 agtaaaaaag ggatgttcac agatgactta cacaagctgg tggatgactg gacaaaggaa
4981 gcagtaggaa attctcttat taagccaagt ttaaaccaac ttaaacaaag tcaacacaaa
5041 ctagagacag aaaactggaa taaagtatct gaaaatactc cgtctactat gggctacaca
5101 tcaacatgga tttcttctct gtcccaaatc cgtggagctg tcccaacttc cttgccacaa
5161 ggactctcac tcccttcatt tcctgggcca ttatcatcat atggaatgcc tcacgtttgt
5221 cagtataatg ctgtggcggg ggcggggtat ccagtacagt gggtaggaat ttcaggaaca
5281 acacaacaat ctgtagtaat tcccgcccaa tctgggggac cattccagcc agggatgaat
5341 atgcaggcat ttccaacttc atcagtgcag aatcctgcca caatccctcc tggtcctaaa
5401 tga
//