LOCUS AY081220 2509 bp mRNA linear HUM 30-JUL-2002
DEFINITION Homo sapiens putative apical iodide transporter (AIT) mRNA,
complete cds.
ACCESSION AY081220
VERSION AY081220.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2509)
AUTHORS Rodriguez,A.M., Perron,B., Lacroix,L., Caillou,B., Leblanc,G.,
Schlumberger,M., Bidart,J.M. and Pourcher,T.
TITLE Identification and characterization of a putative human iodide
transporter located at the apical membrane of thyrocytes
JOURNAL J. Clin. Endocrinol. Metab. 87 (7), 3500-3503 (2002)
PUBMED 12107270
REFERENCE 2 (bases 1 to 2509)
AUTHORS Rodriguez,A.-M., Perron,B., Lacroix,L., Caillou,B., Leblanc,G.,
Schlumberger,M., Bidart,J.-M. and Pourcher,T.
TITLE Direct Submission
JOURNAL Submitted (22-FEB-2002) LRC16V UMR6078, CEA Univ Nice
Sophia-Antipolis CNRS, Bat Jean Maetz, Villefranche sur mer 06300,
France
FEATURES Location/Qualifiers
source 1..2509
/db_xref="H-InvDB:HIT000084243"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q23.1"
/tissue_type="thyroid, kidney and salivary gland"
gene 1..2509
/gene="AIT"
CDS 365..2197
/gene="AIT"
/codon_start=1
/product="putative apical iodide transporter"
/protein_id="AAL88746.1"
/translation="MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKD
FLMGGRRMTAVPVALSLTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEV
FLPVFYKLGITSTYEYLELRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGF
DLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTIL
NDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQA
KLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDY
PGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVY
GALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGF
AISLWVGIGAQIYPPLPERTLPLHLDIQGCNSTYNETNLITTTEMPFTTSVFQIYNVQ
RTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGRKQNLDPRYILTKEDFLSNFD
IFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSDQSGKSNGTRL"
BASE COUNT 581 a 577 c 632 g 719 t
ORIGIN
1 tgtgtagatt cgctggaagc agctggaggc tccagttctc atctgctcag gtgtcccggg
61 cgccttggcg aactcggcca ctccagttcc tcacgtggtg agcactcagg gcagcgggtc
121 gattttccga ggtcccatac ctgggtttga ggggcgcggc tcgcagcggc gggtgcaggg
181 gcgactgcca gccctcaccc cgcctcgggg tgcgttcgga ggccgacacc tggaggacgc
241 ctccagtccc cgcgggacgc cacgcctgcg cgccagggat ccgggataag aagtgcgcgc
301 cgggctccgg ctgcgcgccg cggggccacc agtttgcgcg cagggctcag gcgaccgtgc
361 ggccatggac acgccacggg gcatcggcac cttcgtggtg tgggactacg tggtgttcgc
421 gggcatgctg gtcatctcgg ccgccatcgg catctactac gccttcgctg ggggcggcca
481 gcagacctcc aaggacttcc tgatgggcgg ccgcagaatg accgcagtgc ccgtggcgct
541 gtccctcacc gctagcttca tgtcagccgt cactgtcctg ggcaccccct ccgaggtcta
601 ccgttttggg gccattttta gcatctttgc cttcacctac ttctttgtgg tggtcatcag
661 cgcggaggtc ttcctcccgg tgttctacaa actgggaatt accagcacct acgagtattt
721 agaacttcga tttaacaaat gtgttcgtct ctgtggaaca gtcctcttca ttgttcaaac
781 aattctgtat actggaattg ttatttatgc ccctgccctg gctttgaatc aagtcacagg
841 atttgatctg tggggcgcgg tagtggcaac gggggtggtc tgcacattct actgcacact
901 gggtggtctt aaagcagtta tctggacaga tgtttttcaa gttgggatca tggtggctgg
961 atttgcatcc gtgattatac aggctgtggt gatgcaaggt ggaatcagca ctattttaaa
1021 tgatgcctat gatggtggaa gattaaattt ctggaatttt aatcctaacc ctttgcaaag
1081 acacaccttc tggacaatta ttataggagg gaccttcaca tggaccagca tctacggtgt
1141 caaccaatcc caggtgcaga gatatatttc ttgtaaaagc agattccagg caaaactgtc
1201 tctctacatc aatcttgtgg gactctgggc aatcctcaca tgctcagtgt tttgtgggct
1261 cgccctatat tccaggtacc atgactgtga tccttggaca gccaagaaag tgtctgcacc
1321 agaccagctc atgccttatt tggtactgga cattctgcaa gattatccag gacttcctgg
1381 actttttgtg gcctgtgctt acagtgggac attaagcaca gtgtcctcca gtattaatgc
1441 cttagcagca gtaactgtgg aagatctaat caaaccttac ttcagatcgc tctcagaaag
1501 gtctctgtct tggatttccc aaggaatgag tgtggtgtat ggagccctgt gtattggaat
1561 ggctgcgctg gcgtcactta tgggagcttt gttgcaggca gcactcagcg tatttggtat
1621 ggttggtgga ccacttatgg gcctgttcgc tttgggcatt ttggttccct ttgccaactc
1681 aattggagca cttgttggtc tgatggctgg atttgccatt tctctatggg ttggaattgg
1741 agctcaaata tatcctccac ttcctgagag aacattgcca ttgcaccttg atatccaagg
1801 ctgtaacagc acctacaatg agacaaattt gattacaacc acagaaatgc catttactac
1861 tagtgttttt caaatataca atgttcaaag gactccactg atggataact ggtattcttt
1921 atcatatctg tacttcagca ctgttggaac tttggtaaca ttattagtgg ggatacttgt
1981 cagtttatca acaggaggaa gaaaacagaa cttagacccc agatatatac taaccaaaga
2041 ggacttttta tccaattttg atatttttaa gaaaaagaag catgttttga gctataaatc
2101 acatccagtg gaagatggtg gaactgataa tcctgctttc aaccacattg aattgaactc
2161 agatcagagt ggcaagagca atgggactcg tttgtgaagc tgctctgata ctagatatcc
2221 ttaaatgatg tttcaatttt atatgttttc taagataatt ggatcaggtt ttctttgtgt
2281 gtgtgtgtgt gttgtatcat gagtgtttgg ggggataagg ttttgttaaa acaaagtctg
2341 gactatcttc atttactaca tcattaattg atgttactct ggagtttaga attctggcat
2401 tgacatttcc ctctctttcc tttatttcga tgaagctata attgtgaaaa ttgtaactac
2461 atagatgctg aaaggctaat acacgcatat gaacatgcaa aaaaaaaaa
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