LOCUS AY056583 1709 bp mRNA linear HUM 10-DEC-2002
DEFINITION Homo sapiens transcription cofactor vestigial-like 2 protein (VGL2)
mRNA, complete cds.
ACCESSION AY056583
VERSION AY056583.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1709)
AUTHORS Maeda,T., Chapman,D.L. and Stewart,A.F.
TITLE Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2
transcription factors that promotes skeletal muscle differentiation
JOURNAL J. Biol. Chem. 277 (50), 48889-48898 (2002)
PUBMED 12376544
REFERENCE 2 (bases 1 to 1709)
AUTHORS Maeda,T., Fu,J. and Stewart,A.F.R.
TITLE Human homologs of Drosophila vestigial are tissue-restricted TEF-1
co-activators
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1709)
AUTHORS Maeda,T., Fu,J. and Stewart,A.F.R.
TITLE Direct Submission
JOURNAL Submitted (21-SEP-2001) Cardiovascular Institute, University of
Pittsburgh, 1704 BST, 200 Lothrop Street, Pittsburgh, PA 15213, USA
FEATURES Location/Qualifiers
source 1..1709
/db_xref="H-InvDB:HIT000083957"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q22"
gene 1..1709
/gene="VGL2"
CDS 207..638
/gene="VGL2"
/note="functional cofactor of TEF-1; contains TEF-1
interaction domain; related to Homo sapiens TONDU encoded
by GenBank Accession Number AF137387 and to sequences with
GenBank Accession Numbers Z98880 and AA586760; skeletal
muscle-restricted expression in adults"
/codon_start=1
/product="transcription cofactor vestigial-like 2 protein"
/protein_id="AAL17720.1"
/translation="MSCLDVMYQVYGPPQPYFAAAYTPYHQKLAYYSKMQEAQECNAS
PSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDEH
FSRALSQPSSYSPSCTSSKAPRSSGPWRARRYSLCGASLLS"
BASE COUNT 453 a 421 c 409 g 426 t
ORIGIN
1 gcttctgccc tggagcgcgg tcgggagtaa aatcgcagga gtgggagggt agcgagccag
61 ctggattccg agccgcggag cgcgctggct ttgctccgcc tgatgactcc agagcgcggg
121 tccaagcgcc gcccatgcag cacccctgag ctccggggaa ggagagttaa tgaaaaaaca
181 cttaaccgtc tccgctgcgg agagtcatga gctgtctgga tgttatgtac caagtctatg
241 gtcctccgca gccctacttc gcagccgcct acacccccta ccaccagaaa ctagcctatt
301 attccaaaat gcaggaagcg caggagtgca atgccagccc cagcagcagt ggcagcggca
361 gctcctcatt ttccagccaa accccagcca gtataaaaga ggaagaaggc agcccagaga
421 aagagcgccc accagaggca gagtacatca actcccgctg cgtcctcttc acttatttcc
481 agggggacat cagctccgtg gtggatgaac atttcagcag ggccctgagc caacccagca
541 gctactctcc tagctgtacc agcagcaaag caccaaggag ctctgggccc tggcgagctc
601 gtcgttattc cctctgtggt gcatccctcc tgagctgatc tgctgaccca gggtttcccc
661 ttccccttcc cttctgacca gccttggagg ctcagcatct gtgcctctca ctccgtggat
721 gaggacatgg gggaaggcag agacttcaga cttctcagtg tgttgggaaa accaaaaacc
781 acaactacag aaattcatct aaaaataagt cctgctgctg aaagagcaaa tccaaagact
841 gagttatgtt taatgacttt tggccgaatc actggaaata tctgtggtga gattgctgag
901 tcaggtgatg tgatatcata agctttcttg gaacggggga aagaaaatga aactttttgg
961 tgtgaatatt ttttatgctg atgtgaatta ttttgttagg tagtgtgatt atagcactac
1021 tactgtcaga ttttaaattg tatgtgtact tgcatctaag actgtggtag agaagtaaag
1081 agaagtcaat tccttcttcc tcacctctca gcctccagat cccttcctgc ccatcccttc
1141 cctacaatgc ccactccaga cgcaaagata cacttttttc ctttggactg tgaacatgga
1201 agcctcagcc tgaatgtgag tggcaagtgg cttatctgga gccacctgcc caagtcttac
1261 taaaatgcag ctgttgttag acaactgttg aaaactccag aaatacatca cccaaggtgg
1321 cagttctcag tatttggcag aacaattgca attgcactgg gtatattata tatatatatg
1381 tatgcatata tatcatattt tttacaagga acattttatg atgaaagaag aaacccttct
1441 ctgccttctc tcccacgaat tctgtccctg tatcctctgg atgtaaaaag caaggagaga
1501 ccccaactgt ctccatggag aagaactagg aatcaccaca aggggaagaa atgtacatga
1561 agtctccatt acctcgaatt tttttctcag tctcactggt tgtgatttgg tcactttagt
1621 gttgggacag gggaaagggt ctgtgcgtgg gcaaagctga aggtgatgag gaagaagaga
1681 cgaacattaa agatgtctat ttactatga
//