LOCUS AY055384 3194 bp mRNA linear HUM 01-OCT-2002
DEFINITION Homo sapiens type II transmembrane serine protease 6 (TMPRSS6)
mRNA, complete cds.
ACCESSION AY055384
VERSION AY055384.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3194)
AUTHORS Hooper,J.D. and Quigley,J.P.
TITLE TMPRSS6, a new type II transmembrane serine protease
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3194)
AUTHORS Hooper,J.D. and Quigley,J.P.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) Vascular Biology, The Scripps Research
Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..3194
/db_xref="H-InvDB:HIT000083936"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q12.2-q13.1"
gene 1..3194
/gene="TMPRSS6"
CDS 115..2550
/gene="TMPRSS6"
/codon_start=1
/product="type II transmembrane serine protease 6"
/protein_id="AAL16414.1"
/translation="MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSK
RKARGYLRLVPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQD
LTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPE
HRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNST
LGCYRYSYVGQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYD
VAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQA
CEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQK
YDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYG
LYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPK
VCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC
DCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSM
ASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSA
AVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ
VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTR
ITGVISWIQQVVT"
BASE COUNT 569 a 1000 c 1010 g 615 t
ORIGIN
1 cttgagccag acccagtcca gctctggtgc ctgccctctg gtgcgagctg acctgagatg
61 cacttccctc ctctgtgagc tgtctcggca cccacttgca gtcactgccg cctgatgttg
121 ttactcttcc actccaaaag gatgcccgtg gccgaggccc cccaggtggc tggcgggcag
181 ggggacggag gtgatggcga ggaagcggag ccggagggga tgttcaaggc ctgtgaggac
241 tccaagagaa aagcccgggg ctacctccgc ctggtgcccc tgtttgtgct gctggccctg
301 ctcgtgctgg cttcggcggg ggtgctactc tggtatttcc tagggtacaa ggcggaggtg
361 atggtcagcc aggtgtactc aggcagtctg cgtgtactca atcgccactt ctcccaggat
421 cttacccgcc gggaatctag tgccttccgc agtgaaaccg ccaaagccca gaagatgctc
481 aaggagctca tcaccagcac ccgcctggga acttactaca actccagctc cgtctattcc
541 tttggggagg gacccctcac ctgcttcttc tggttcattc tccaaatccc cgagcaccgc
601 cggctgatgc tgagccccga ggtggtgcag gcactgctgg tggaggagct gctgtccaca
661 gtcaacagct cggctgccgt cccctacagg gccgagtacg aagtggaccc cgagggccta
721 gtgatcctgg aagccagtgt gaaagacata gctgcattga attccacgct gggttgttac
781 cgctacagct acgtgggcca gggccaggtc ctccggctga aggggcctga ccacctggcc
841 tccagctgcc tgtggcacct gcagggcccc aaggacctca tgctcaaact ccggctggag
901 tggacgctgg cagagtgccg ggaccgactg gccatgtatg acgtggccgg gcccctggag
961 aagaggctca tcacctcggt gtacggctgc agccgccagg agcccgtggt ggaggttctg
1021 gcgtcggggg ccatcatggc ggtcgtctgg aagaagggcc tgcacagcta ctacgacccc
1081 ttcgtgctct ccgtgcagcc ggtggtcttc caggcctgtg aagtgaacct gacgctggac
1141 aacaggctcg actcccaggg cgtcctcagc accccgtact tccccagcta ctactcgccc
1201 caaacccact gctcctggca cctcacggtg ccctctctgg actacggctt ggccctctgg
1261 tttgatgcct atgcactgag gaggcagaag tatgatttgc cgtgcaccca gggccagtgg
1321 acgatccaga acaggaggct gtgtggcttg cgcatcctgc agccctacgc cgagaggatc
1381 cccgtggtgg ccacggccgg gatcaccatc aacttcacct cccagatctc cctcaccggg
1441 cccggtgtgc gggtgcacta tggcttgtac aaccagtcgg acccctgccc tggagagttc
1501 ctctgttctg tgaatggact ctgtgtccct gcctgtgatg gggtcaagga ctgccccaac
1561 ggcctggatg agagaaactg cgtttgcaga gccacattcc agtgcaaaga ggacagcaca
1621 tgcatctcac tgcccaaggt ctgtgatggg cagcctgatt gtctcaacgg cagcgacgaa
1681 gagcagtgcc aggaaggggt gccatgtggg acattcacct tccagtgtga ggaccggagc
1741 tgcgtgaaga agcccaaccc gcagtgtgat gggcggcccg actgcaggga cggctcggat
1801 gaggagcact gtgactgtgg cctccagggc ccctccagcc gcattgttgg tggagctgtg
1861 tcctccgagg gtgagtggcc atggcaggcc agcctccagg ttcggggtcg acacatctgt
1921 gggggggccc tcatcgctga ccgctgggtg ataacagctg cccactgctt ccaggaggac
1981 agcatggcct ccacggtgct gtggaccgtg ttcctgggca aggtgtggca gaactcgcgc
2041 tggcctggag aggtgtcctt caaggtgagc cgcctgctcc tgcacccgta ccacgaagag
2101 gacagccatg actacgacgt ggcgctgctg cagctcgacc acccggtggt gcgctcggcc
2161 gccgtgcgcc ccgtctgcct gcccgcgcgc tcccacttct tcgagcccgg cctgcactgc
2221 tggattacgg gctggggcgc cttgcgcgag ggcggcccca tcagcaacgc tctgcagaaa
2281 gtggatgtgc agttgatccc acaggacctg tgcagcgagg tctatcgcta ccaggtgacg
2341 ccacgcatgc tgtgtgccgg ctaccgcaag ggcaagaagg atgcctgtca gggtgactca
2401 ggtggtccgc tggtgtgcaa ggcactcagt ggccgctggt tcctggcggg gctggtcagc
2461 tggggcctgg gctgtggccg gcctaactac ttcggcgtct acacccgcat cacaggtgtg
2521 atcagctgga tccagcaagt ggtgacctga ggaactgccc ccctgcaaag cagggcccac
2581 ctcctggact cagagagccc agggcaactg ccaagcaggg ggacaagtat tctggcgggg
2641 ggtgggggag agagcaggcc ctgtggtggc aggaggtggc atcttgtctc gtccctgatg
2701 tctgctccag tgatggcagg aggatggaga agtgccagca gctgggggtc aagacgtccc
2761 ctgaggaccc aggcccacac ccagcccttc tgcctcccaa ttctctctcc tccgtcccct
2821 tcctccactg ctgcctaatg caaggcagtg gctcagcagc aagaatgctg gttctacatc
2881 ccgaggagtg tctgaggtgc gccccactct gtacagaggc tgtttgggca gccttgcctc
2941 cagagagcag attccagctt cggaagcccc tggtctaact tgggatctgg gaatggaagg
3001 tgctcccatc ggaggggacc ctcagagccc tggagactgc caggtgggcc tgctgccact
3061 gtaagccaaa aggtggggaa gtcctgactc cagggtcctt gccccacccc tgcctgccac
3121 ctgggccctc acagcccaga ccctcactgg gaggtgagct cagctgccct ttggaataaa
3181 gctgcctgat ccaa
//