LOCUS AY055204 4999 bp mRNA linear HUM 01-APR-2002
DEFINITION Homo sapiens COASTER mRNA, complete cds.
ACCESSION AY055204
VERSION AY055204.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4999)
AUTHORS Heldens,I.M. and Dechering,K.J.
TITLE Isolation of a novel coactivator for steroid receptors that alters
the intrinsic activity of the estrogen receptor alpha liganded with
SERMs
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4999)
AUTHORS Heldens,I.M. and Dechering,K.J.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) Target Discovery, N.V. Organon, Molenstraat
110, Oss 5340 BH, The Netherlands
FEATURES Location/Qualifiers
source 1..4999
/db_xref="H-InvDB:HIT000083934"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 226..3267
/note="coactivator for steroid receptors"
/codon_start=1
/product="COASTER"
/protein_id="AAL17975.1"
/translation="MGDPGSEIIESVPPAGPEASESTTDENEDDIQFVSEGPLRPVLE
YIDLVSSDDEEPSTSYTDENIKRKDHIDYQKDKVALTLARLARHVEVEKQQKEEKNRA
FREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINCGTKSSFRRGG
HTWVSGKPTLCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFFSSFACVVCY
KKFVTQQQYRDHLFDKEATDDGHNNNLLPQIIQCFACPNCFLLFSRKEECSKHMSGKN
HFHQSFKLGDNKGIAHPISFPSFAKKLLISLCKDVPFQVKCVACHKTLRSHMELTAHF
RVHCRNAGPVAVAEKSITQVAEKFILRGYCPDCNQVFVDETSTQNHKQNSGHKVRVIN
SVEESVLLYCHSSEGNKDPSSDLHLLLDQSKFSSLKRTMSIKESSSLECIAIPKKKMN
LKDKSHEGVACVQKEKSVVKTWFCECNQRFPSEDAVEKHVFSANTMGYKCVVCGKVCD
DSGVIRLHMSRIHGGAHLNNFLFWCRTCKKELTRKDTIMAHVTEFHNGHRYFYEMDEV
EGETLPSSSTTLDNLTANKPSSAITVIDHSPANSSPRGKWQCRICEDMFDSQEYVKQH
CMSLASHKFHRYSCAHCRKPFHKIETLYRHCQDEHDNEIKIKYFCGLCDLIFNVEEAF
LSHYEEHHSIDYVFVSEKTETSIKTEDDFPVIETSNQLTCGCRESYICKVNRKEDYSR
CLQIMLDKGKLWFRCSLCSATAQNLTDMNTHIHQVHKEKSDEEEQQYVIKCGTCTKAF
HDPESAQQHFHRKHCFLQKPSVAHFGSEKSNLYKFTASASHTERKLKQAINYSKSLDM
EKGVENDLSYQNIGGNTNWKPPLNCKIYNYLNRIGCFFLHPRCSKRKDAADFAICMHA
GRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISD
TTKECDSDDNMGAKNTSIGEEFISTEDVELEEAIRRSLEEM"
BASE COUNT 1614 a 858 c 1037 g 1490 t
ORIGIN
1 ggaagcccgg gagtgagaga aagcggctcc gggggcatag cgggccagta agggccgctc
61 ctcctttgaa gaggttttgc gtctctttcc gccggtggcg tcggcgctca cgcaggggcg
121 ggtcccggta gcgccaggcg gtgcagggcg ggaaggggat tcgtggcgac ggcggcggca
181 agggacagca ggagcagtgg tgctgtcagc gcggccgtcg gagacatggg agacccgggg
241 tcggagataa tagaatctgt ccctccagct ggccctgagg catctgagtc aacaacggat
301 gaaaatgaag acgacattca gtttgtcagt gaaggaccat tacgacctgt tcttgaatac
361 attgatctgg tcagcagtga tgatgaagag cctagcacct cttatactga tgagaatatt
421 aaacgtaaag accatattga ttatcagaag gataaagttg ctttaactct ggctcgtcta
481 gcccgccatg ttgaagtgga gaaacagcag aaagaagaga agaatagagc attcagagaa
541 aaaattgatt ttcagcatgc tcatgggtta caagaattgg aatttattcg aggacattct
601 gatacagaag cagcaagact gtgtgtggac cagtggctaa aaatgccagg actcaaaaca
661 ggcacaatta attgtggaac aaaaagttca ttccgaagag gaggccacac gtgggtgtct
721 gggaaaccaa ctttatgtcc tataatgcac tgtaacaagg agtttgacaa tgggcacctt
781 ctcttaggac atttgaaaag gttcgatcac tctccatgtg atccaacaat tacactacat
841 ggacctttct tcagctcctt tgcttgtgta gtatgttata aaaaatttgt tactcaacaa
901 caatatagag atcacctttt tgataaggaa gccacagatg atggacataa caacaacctt
961 cttcctcaga ttattcagtg ttttgcatgt ccaaattgct tccttctttt tagcagaaag
1021 gaggagtgtt caaagcatat gtctggaaag aatcatttcc atcagagttt caaactgggt
1081 gataacaaag gaattgcaca tccaatatct ttcccatctt ttgcaaagaa acttttgatc
1141 tctctgtgca aagatgttcc ctttcaagtt aagtgtgtgg cctgccacaa gacactgcgt
1201 tcccacatgg agctcactgc ccatttcaga gttcattgtc gaaatgctgg acctgtagct
1261 gtagctgaga agagcattac ccaggttgca gagaaattca tattaagagg ttattgtcca
1321 gattgcaatc aagtctttgt ggatgaaacc agcacccaaa atcataagca gaattcagga
1381 cacaaagtcc gagtcattaa ctcagtggaa gaatcagtct tactctattg ccacagcagc
1441 gaagggaaca aggatccttc ttctgacttg catttattgt tggatcaatc aaaattttca
1501 tcacttaaaa gaaccatgtc tattaaagaa tctagctcac tggagtgcat tgccattcca
1561 aaaaagaaga tgaatttaaa agataaaagc catgaaggtg ttgcttgtgt ccagaaagaa
1621 aaatcagtag ttaaaacctg gttctgtgaa tgcaatcagc gattcccaag tgaagatgca
1681 gtagaaaagc atgttttctc agcaaacaca atgggttata aatgtgtggt ctgtggaaag
1741 gtatgtgatg attcaggggt cattcgttta cacatgagcc ggattcacgg aggggcacat
1801 ttaaataact ttcttttctg gtgtcggaca tgcaaaaagg agttaacaag gaaagatact
1861 atcatggcac atgtgactga atttcataat ggacacagat atttttatga gatggatgag
1921 gtagaaggtg aaactttgcc atcatcctct acaacattgg ataatttgac tgctaacaag
1981 ccttcatcag ctattactgt tattgatcat tccccggcaa atagttctcc gaggggtaaa
2041 tggcaatgcc ggatttgtga agatatgttt gattcccagg aatatgtaaa acagcactgc
2101 atgtctttgg caagccacaa gtttcataga tacagctgtg ctcactgcag aaagcctttt
2161 cataagatag aaacattgta ccgacattgc caagatgagc atgacaatga gataaagatt
2221 aaatacttct gtgggctttg tgatcttatc tttaatgtgg aagaagcatt tctgagtcat
2281 tatgaggagc accacagcat agattatgta tttgtgtcag aaaaaactga aacttcaatt
2341 aaaaccgaag atgattttcc agtaatagag accagtaacc agttaacttg tggttgccgt
2401 gagagttaca tctgtaaagt caacagaaaa gaagattata gcagatgtct ccaaatcatg
2461 ctggataaag gaaaactgtg gtttcgctgc agtttatgtt cggcaacagc acagaattta
2521 accgacatga acactcatat ccatcaagtg cacaaagaaa agagtgatga ggaggagcag
2581 cagtatgtaa tcaagtgtgg cacctgcacc aaagcatttc atgatcctga gagtgcacag
2641 cagcatttcc atagaaaaca ttgcttctta cagaaaccca gtgtggctca ttttggatct
2701 gaaaaatcaa acctgtacaa gtttactgct agtgcctcac atacagagag aaaactgaaa
2761 caggcaataa actattcaaa aagtttagac atggagaaag gagttgagaa tgacctaagc
2821 tatcagaata taggaggaaa caccaattgg aagcctccgc tcaactgtaa gatttataac
2881 tacctgaaca ggattggatg cttcttcctt catcctcgct gtagtaaaag aaaagatgct
2941 gctgattttg ccatatgtat gcatgctggc cgtctagatg aacaactacc caagcaaatt
3001 cctttcacca tcctctcagg agatcaaggt tttctggagc tagagaatca atttaagaag
3061 actcagaggc cagctcatat actaaaccct caccacttag agggagatat gatgtgtgcc
3121 ttgttaaata gcatatctga taccaccaaa gaatgtgaca gtgatgataa catgggtgcc
3181 aaaaatactt caataggaga agaatttata tccacagaag atgtggaatt agaagaagct
3241 attagaagaa gtcttgagga aatgtaatta aagatattac cacacaacat caagtggcct
3301 tgaagagact gagataacga attcttgagt ttgttttcta aaggagacca gaaatccact
3361 attacaaatg tatttgaaaa catgtttttg ctttcatatg ttcaaaattt gatctttgtt
3421 ttgtattttt gtgctaatgt gcaaacatgt acagaagaaa tagaatacat gttcatgcaa
3481 atataaatta tgtattctaa tataggtgta acagtttccc agttaacttt gaatttatat
3541 atttagattt aaaggattaa aaaaaaggaa agctcttgac agttgtttcc caaatagcat
3601 tagttcttta attttatttg tactgtacaa atgatgctag tttatttttt tagcagtgaa
3661 aatgaatata aaaaaggtga cataggtcaa gttttccata aattctactt ctcatgtggc
3721 actattatat aatacctttg agatctttgt ttatgtttat tagaagaggg taatggaaac
3781 tgatcatgga aacatttaaa attttatcag caatgttctt tgtgggtgcc atgcatatgt
3841 aaattattgc tttaattaga gcagcacatt gctaaaataa aaaatacacc ttaattttta
3901 agaaataatt taaatgaaac aatttccatt ccttttacct gcttagactt ttatgtgact
3961 tgtatggtct cctggttaaa gggaatggtg tcagaatatt tgcataaaat tatttttcat
4021 aacagtcctt ttttatatat tggtgtaaac ataatattct tcaagaaata atgttgaaag
4081 cctactcagg aataatcttc cttaactctt taaattttta tttcatgtga agtgttttca
4141 gtttagttat tcactgaatt gtcagtttcc ttcatttggt attacatatt taattcttaa
4201 atattgaggc cccattgtga gtaataaaaa atacgacata agtagaagac taagaagggc
4261 ttgtcatatt atctttgtgt atatgcttca tgttatttaa ccagaaatgt cttatctcta
4321 aaaattttta gtagtaatta tttaccaaac ttaaaaacat ttctataaat ataaagcttt
4381 tctttatatt taagacaaaa tataaaggct agaatttggt tccttctctg taacactaaa
4441 tattttagtg tgaaattgaa tttttttatt actatagtct tttcaatcta taatttgtgt
4501 ttttaatttc ttgatatgtc acttctgttc ctccctgctt gcatttttta aaaactagac
4561 attgtggctt gagaatttat caatcatctt tccgaaatga ccacattgtg cttttagttt
4621 gtatgtttaa gtggtcaagc aaggctctag gaggtagtca ctgagctgga ccttaaacac
4681 atctgcagga gctcacaaaa tgggagcaaa agaggcattc cagaaagaag agtagttaag
4741 cagatgtggg ggcagggcaa gaggagacag caccttgttg ccagagattc tacacaaagg
4801 tgtgatggac actgatgctc tattaagaag cttttgtggt gtgtgtggta gagaataatt
4861 aaggcttctg ataagacagg aaagggatat ttcatcatga ctgttaagaa aaggtaactg
4921 ggttgtttaa tgttttaatt gataattgtc actgatcgta tttctacttg ttaaataatt
4981 aaaaatcatc ttaaaattc
//