LOCUS AY053503 5107 bp mRNA linear HUM 22-OCT-2001
DEFINITION Homo sapiens ether-a-go-go-like potassium channel 1 mRNA, complete
cds.
ACCESSION AY053503
VERSION AY053503.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5107)
AUTHORS Baxter,D.F., Kirk,M., Garcia,A.F., Raimondi,A., Holmqvist,M.H.,
Bojanic,D., DiStefano,P.S., Curtis,R. and Xie,Y.
TITLE A novel membrane potential-sensitive fluorescent dye improves
cell-based assays for ion channels
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5107)
AUTHORS Curtis,R.
TITLE Direct Submission
JOURNAL Submitted (29-AUG-2001) Neurobiology, Millennium Pharmaceuticals,
Inc., 75 Sidney Street, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..5107
/db_xref="H-InvDB:HIT000083909"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
CDS 196..3519
/note="ELK1"
/codon_start=1
/product="ether-a-go-go-like potassium channel 1"
/protein_id="AAL15429.1"
/translation="MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVY
CSDGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQIEKSLEEKTEFKGEIMFYKK
NGSPFWCLLDIVPIKNEKGDVVLFLASFKDITDTKVKITPEDKKEDKVKGRSRAGTHF
DSARRRSRAVLYHISGHLQRREKNKLKINNNVFVDKPAFPEYKVSDAKKSKFILLHFS
TFKAGWDWLILLATFYVAVTVPYNVCFIGNDDLSTTRSTTVSDIAVEILFIIDIILNF
RTTYVSKSGQVIFEARSICIHYVTTWFIIDLIAALPFDLLYAFNVTVVSLVHLLKTVR
LLRLLRLLQKLDRYSQHSTIVLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEV
GWLHELGKRLESPYYGNNTLGGPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIF
SICTMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRML
EYFQTTWSVNNGIDSNELLKDFPDELRSDITMHLNKEILQLSLFECASRGCLRSLSLH
IKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKDSMVLAILGKGDLIGANLSIKDQV
IKTNADVKALTYCDLQCIILKGLFEVLDLYPEYAHKFVEDIQHDLTYNLREGHESDVI
SRLSNKSMVSQSEPKGNGNINKRLPSIVEDEEEEEEGEEEEAVSLSPICTRGSSSRNK
KVGSNKAYLGLSLKQLASGTVPFHSPIRVSRSNSPKTKQEIDPPNHNKRKEKNLKLQL
STLNNAGPPDLSPRIVDGIEDGNSSEESQTFDFGSERIRSEPRISPPLGDPEIGAAVL
FIKAEETKQQINKLNSEVTTLTQEVSQLGKDMRNVIRLLENVLSPQQPSRFCSLHSTS
VCPSRESLQTRTSWSAHQPCLHLQTGGAAYTQAQLCSSNITSDIWSVDPSSVGSSPQR
TGAHEQNPADSELYHSPSLDYSPSHYQVVQEGHLQFLRCISPHSDSTLTPLQSISATL
SSSVCSSSETSLHLVLPSRSEEGSFSQGTVSSFSLENLPGSWNQEGMASASTKPLENL
PLEVVTSTAEVKDNKAINV"
BASE COUNT 1486 a 1136 c 1092 g 1393 t
ORIGIN
1 cctgccacag ccggggcggc tggaactctc tccctttctc cctccatcct tccacttccc
61 ctgctcggcc ccgccgtcag gccgggtccc ccttccctgc cgtcatcagg ttccccttct
121 cccttcttgg cactttcctt tcgaaccatc cttctggaca aactttgatg gagaatttca
181 caccacgctg gaaaaatgcc ggttatgaaa ggattactgg cgccgcaaaa caccttcctg
241 gacaccatcg ccacccgttt tgacggaaca catagcaact tcatccttgc caatgcccag
301 gtggctaagg gtttccccat agtctactgt tccgatggct tctgcgagct tgctggattt
361 gcccgaactg aagtcatgca gaagagttgt agctgcaagt tcttatttgg ggttgaaacc
421 aatgagcaac tgatgcttca aatagaaaag tcactggagg agaaaacaga attcaaagga
481 gaaattatgt tctacaagaa aaacgggtct ccattttggt gcctactgga tattgttccc
541 ataaagaatg aaaaaggaga tgtagtactt tttctggcct cgttcaaaga tataacagat
601 acaaaagtga agattactcc agaagataaa aaagaagaca aagtcaaagg aagatcaaga
661 gcagggaccc actttgactc agcccggaga cggagtcgag cagtccttta tcacatctct
721 gggcacctgc aaagaagaga aaagaacaaa ttgaaaataa ataacaatgt ttttgtagat
781 aaaccagcat ttccggagta taaagtttct gatgcaaaaa agtccaaatt catacttctg
841 cattttagca cttttaaagc tggctgggac tggcttattt tgttggcaac gttttatgtt
901 gctgtgactg taccttacaa cgtttgcttt attggcaatg acgacctgtc cacaactcgg
961 agcacaaccg tcagtgacat tgcagtggag attcttttta ttatagatat tattttaaat
1021 ttccgaacaa cttatgtcag caagtctggc caagttatct ttgaagcaag atcaatttgc
1081 atccactatg tcacaacctg gttcatcatt gatttaatcg ctgccctgcc ttttgatctt
1141 ctgtatgctt tcaacgtcac agtggtgtct ctcgtgcatc ttctaaagac agtgcgcctc
1201 ttgcgtcttt tgcgtctgct gcagaagtta gaccgctatt cccaacacag tactatcgtc
1261 ctgactctgc tcatgtccat gtttgcactc cttgcacact ggatggcgtg tatctggtac
1321 gtcattggaa aaatggagag ggaagacaac agccttctga agtgggaagt tggttggctt
1381 catgagttgg gaaagagact ggaatctcca tactatggca acaatacctt ggggggcccg
1441 tcgatccgaa gtgcctatat tgccgctctg tacttcacgc tgagcagcct caccagcgtg
1501 ggttttggga acgtctctgc taatacagat gcagaaaaga tcttctccat ctgcaccatg
1561 ctgattggtg ccttgatgca cgccttggtg tttggaaacg tgacagcaat catacagagg
1621 atgtactcca gatggtccct ctatcacact agaactaagg atctgaaaga tttcatccgt
1681 gtccatcact tgccccaaca actcaagcag aggatgctcg aatattttca aacaacctgg
1741 tcagtcaaca atggaataga ttcaaatgag cttttgaaag actttccaga tgaactgcgt
1801 tctgacatca ctatgcactt gaacaaggag atcttacagt tgtccctttt tgaatgtgcc
1861 agccggggct gcctcaggtc tctgtctcta cacatcaaaa cctctttctg tgctccgggg
1921 gagtatctgc tgcgtcaagg ggatgctttg caggccatct actttgtatg ctcgggctcc
1981 atggaagttc ttaaagacag catggtgctg gctattcttg ggaaagggga tttaattgga
2041 gcaaatctat caattaagga ccaagtgatc aagaccaatg cagatgtaaa ggctttaacc
2101 tactgtgatc tccagtgtat catcctcaaa ggactctttg aagtgctaga cctttaccca
2161 gaatatgctc acaaattcgt ggaagacatt cagcatgacc tcacatacaa cctccgagaa
2221 ggtcatgaga gtgatgtgat atcaagacta tcaaacaaat ctatggtctc acagtcagag
2281 cccaagggaa atggcaacat caacaagcga ctcccatcca ttgtggaaga tgaggaagag
2341 gaggaggagg gggaggaaga ggaggcagtc tccctctctc ccatctgcac aaggggatct
2401 tcttcgcgca acaagaaggt tggaagcaat aaagcctacc tgggcttaag cttaaagcaa
2461 ctggcctcgg gaacggtgcc ctttcactcg cctatcagag tctccaggtc aaattccccc
2521 aaaaccaagc aggaaattga cccccccaac cataataaaa ggaaagagaa gaacttgaaa
2581 ttgcaacttt caactttgaa taatgctgga cccccagacc tcagtccaag gattgttgat
2641 ggaattgaag atggaaacag cagtgaagaa agtcagactt ttgattttgg ctctgaacga
2701 atcagatcag agcccagaat ttctcctcct cttggagatc cagagattgg agctgctgtt
2761 ctcttcatca aagcagagga gaccaagcag cagataaaca aactcaacag tgaggtaaca
2821 acattgactc aggaagtttc tcagttgggt aaagacatga gaaatgtgat ccggcttctg
2881 gaaaacgttc tgtcacctca gcagccatca cggttttgct ctttgcacag cacctctgtg
2941 tgtccctcca gggagagctt acagaccaga acgagctgga gtgcacacca gccttgccta
3001 cacttgcaaa caggcggggc tgcttatacc caagcacaac tttgtagcag taatatcacc
3061 tcagacattt ggagtgtgga tccctcctct gtggggagca gcccccaacg aactggagct
3121 catgagcaaa atcctgcaga cagtgaactt tatcattctc caagccttga ttattcacct
3181 tcccactacc aggttgtcca agaaggtcat ttgcaatttt taaggtgcat ctctccacat
3241 tcagattcta cgttgacgcc tctgcagtcc atttcagcaa ctctctcatc ttctgtctgc
3301 tcctcttcgg aaacatcttt gcacctagtt ctcccaagca gatcagagga gggcagcttc
3361 agtcagggaa ctgtgagttc cttcagtctg gaaaacttac caggatcttg gaaccaggaa
3421 ggaatggcat cagcttctac aaaacctttg gagaaccttc cactggaagt tgtcacaagc
3481 acagcagaag tgaaagataa caaagccata aatgtatgat attagtgccc atgatgcagc
3541 agctaatttc aaacctacca ctgcatgaca gttttagttt gcctttttgc ctctggtggg
3601 catgaagact gagcaaagct gggaatcctg cagaaaagag tgtgaggagc cagggaaagg
3661 cagaaccacc tccatgctgt agcaaacaat ttctagatac tagaagcata atagaaacat
3721 ttttctgtac aggtattaaa ctactggtct gtttgacaga ctttggtaac aatccaaaga
3781 ccctgagggt ctgagcagct agaagtccta gacaaagaac ttgtggatga cttttgtccc
3841 atgtggcttt tgtgaagtat ggcaaaggtt tttcatgagt gcctgattgt tattcctgaa
3901 caatatccat agcactgttg gcctcaggag tgcacagctc ctgctgatgt atttttcttt
3961 ttgtgaaggc aaagggacaa ttatcactgc atgtcatctc ctagacaatc agtcaaatag
4021 agctggtggc cagtggttag ctattcgcac gttatttgcc atgtaaatga aaacgtcttt
4081 atttatcaaa aaaacacaga ggctattttt atatccttgg tatgaaatat gtatttaaac
4141 tatttaaata tttataaaga aatgaatgtt ttcttttcat tttggtaaaa aaaaagcttg
4201 ctgttttaac aagaaatgca ctactgttgt gtatagtaga tcaaaaatta tttattacta
4261 agaggatgta gtttccaaag gaatccccca ttttttctgc atgcagtttg caacaaatgt
4321 attctcatgc ttctggatta taaaagaaaa gtgaagtcat attttgttaa tgaaataaaa
4381 acatggactg agtgtcaact acatgagctt tggcatgggg atagagaggc tccatctagg
4441 ctctgccaac tcatgtcaat gacatgattt aaggtccgtt gtgccagcag aaatgtctct
4501 cctctaggta tcgtattttg ttgctcaaga atccaaaatg ggtctgtgga catagggcaa
4561 tttggggctc aaagtgaggg agaaaacctg ggtgtgtcct ttcccagtgc ttttctttta
4621 caagaggtag tagactagtg gaaatcccca aatggagcca agacttctga gctataactt
4681 gtgggagtaa taccagcttg caatgggtca gcactttacc ttttttcttt aaggctccca
4741 acaatgctat acagcgcagt tgtttccatt cctattttta ataaatctca ggggaagcct
4801 cagagattac acagttagga tgctgacaca gtctagaatc cataatgctc cctacatctc
4861 acactaacag gcaaattcag atgctgggat tggcaatgat ttaagcacct tcactaaagt
4921 cttattttat gttttagaac agttacagtc taattgtctt ggacattttg ggaagatata
4981 ttgggttcac attctggagt tctctttatt ttccaccaca aaaaataatc tgagaattgt
5041 atcattaaaa gtatctaaac acacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
5101 aaaaaaa
//