LOCUS AY049733 7274 bp mRNA linear HUM 25-JAN-2002
DEFINITION Homo sapiens ARAP2 mRNA, complete cds.
ACCESSION AY049733
VERSION AY049733.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7274)
AUTHORS Miura,K., Jacques,K.M., Stauffer,S., Kubosaki,A., Zhu,K.,
Hirsch,D.S., Resau,J., Zheng,Y. and Randazzo,P.A.
TITLE ARAP1: a point of convergence for Arf and Rho signaling
JOURNAL Mol. Cell 9 (1), 109-119 (2002)
PUBMED 11804590
REFERENCE 2 (bases 1 to 7274)
AUTHORS Miura,K., Jacques,K.M., Stauffer,S., Kubosaki,A., Zhu,K., Resau,J.,
Zheng,Y. and Randazzo,P.A.
TITLE Direct Submission
JOURNAL Submitted (29-JUL-2001) Laboratory of Cellular Oncology, National
Cancer Institute, 37 Convent Drive, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..7274
/db_xref="H-InvDB:HIT000083834"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 254..5368
/note="KIAA0580"
/codon_start=1
/product="ARAP2"
/protein_id="AAL12170.1"
/translation="MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDS
LLQKIGISPTGHRRRILKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNI
CIELSNSGSVQTSSPPQLETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPH
LNLGSLNDSLFGSDNIKIESLITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLS
FVGCSTSGTNSGNGTNGLLEGSPPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVS
RPSRSFLLRHRPVPEIPGSTKGVSGSYFRERRNVATSTEKSVAWQNSNEENSSSIFPY
GETFLFQRLENSKKRSIKNEFLTQGEALKGEAATATNSFIIKSSIYDNRKEKISEDKV
EDIWIPREDKNNFLIDTASESEYSTVEECFQSLRRKNSKASKSRTQKALILDSVNRHS
YPLSSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFD
GLSISYYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWI
SILLNALKSQSLTSQSQAVVTPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSG
LGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETL
SDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSL
KMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGK
FRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKK
AGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLYQAPSAASKLSSEKK
LLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFE
IYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALD
QWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGR
TLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGC
KYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKE
LYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAH
NLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFE
VIENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSI
KEGILKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGV
KKKMKPPTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRS
ITKNPKIGGLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERAS
MVAHCLEHKDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKAT
LDSDHKLPSRVIEELNVVLQRSRTLPKELQDEQILK"
BASE COUNT 2406 a 1270 c 1494 g 2104 t
ORIGIN
1 gaggaccgag cgcccaaggc tgggagagac gccggcgctg agcttcccag cgccgcctca
61 cctcgctttt cgaactccgc gacccgagcg caaggcttaa gcaggtaaag cagtcactgt
121 gaagaaaata acattttaag aaacttttct gtcacaattg atagaggaaa agccagtaga
181 gaagtacatc ttcttgtgtg tgtgtctcat cgtgccactt tttgtaactc agcttagtaa
241 tgaagccacc attatgtcct cagtcagtga agtaaatgtg gatataaaag atttcctaat
301 gagcattaat ttggagcagt atctcttaca tttccatgag tctggtttta ctactgtgaa
361 ggactgtgca gcaataaatg acagcctgct gcagaaaatt ggaatatcac ctacaggtca
421 ccgtaggagg atacttaaac agttacagat aatcttgtca aaaatgcaag atattccaat
481 atatgcaaat gttcataaaa ctaagaagaa tgatgaccct tcaaaggatt accatgttcc
541 atcttctgat cagaatatct gcatagaact ttccaattct ggtagtgttc agacatctag
601 cccaccgcag ttggagactg ttagaaaaaa tcttgaagac agtgatgcaa gtgtggaaag
661 aagccagtat cctcaatcag atgataagct gtctcctcct aaacgcgact tccccactgc
721 agaggaacca cacctgaatt tgggttcttt gaatgattct ttatttggta gtgacaatat
781 taaaatagaa tcattgatta caaagaagac tgtggatcac acagttgaag aacaacaaac
841 agaaaaagtt aaattgatca cagaaaatct cagtaagctc cctaatgcag actctgaatg
901 cctttctttt gttggctgtt caacatcagg aacaaattct ggaaatggaa caaatggttt
961 attagaagga tcaccaccat ccccattctt taagtttcaa ggagaaatga ttgtaaatga
1021 cttgtatgtt ccatcatcac caatcctagc acctgtgaga agtcgtagca agttggtttc
1081 aagaccatct cgatcttttc tgctaagaca tcgacctgta ccagagattc cagggtcaac
1141 aaaaggagtt tctgggagct atttccgtga aagaagaaat gttgctacct caactgaaaa
1201 atctgtggca tggcaaaatt caaatgagga gaattcatct tccatctttc cttatggaga
1261 gacctttctc ttccagagac tagaaaattc caagaagcga tctataaaga atgaattttt
1321 gacccaggga gaagcactca aaggggaagc agctactgca acaaactctt ttatcatcaa
1381 atcaagcata tacgataaca gaaaggagaa aataagcgag gacaaggtgg aagatatttg
1441 gatacctcga gaggacaaaa acaatttttt gatagacact gcttctgaat cagaatactc
1501 aacagtagaa gaatgctttc agagtttaag aagaaaaaat tcaaaggcat ctaaatctag
1561 gactcaaaaa gccttgattt tggactccgt taataggcac agttatccgt taagctcaac
1621 aagtggaaat gctgattcat cagccgtttc ttcacaggca atatctccct atgcctgctt
1681 ttatggagca tctgcaaaga aggttaaatc aggatggctg gataaactct ctcctcaagg
1741 aaaacgcatg tttcaaaaga gatgggtgaa atttgatggc cttagcattt cttactacaa
1801 taatgagaag gagatgtatt cgaaaggaat aattcccctt tctgctatat caacagtacg
1861 agttcaagga gacaacaaat ttgaagttgt tacaacacaa agaacttttg tttttagagt
1921 agaaaaagaa gaggagagaa atgactggat cagcatacta ttaaatgcac tgaaatcaca
1981 atcccttacc tcgcagtctc aagctgttgt tacacctgag aaatgtggat atcttgaatt
2041 gagaggctat aaggcaaaaa tttttactgt gttaagtgga aacagtgtgt ggctttgcaa
2101 aaacgaacag gattttaaga gtggacttgg tattaccata attcctatga atgtagcaaa
2161 tgtaaagcaa gtggaccgaa ctgtgaaaca atcttttgaa ataatcactc cctacaggag
2221 tttcagcttt acagccgaga ctgaaaagga gaaacaagac tggattgaag ctgtgcagca
2281 atcaatagca gaaactctct ctgattatga agtagctgag aagatttggt tcaatgaatc
2341 caacaggagc tgtgcagatt gtaaagcccc agatcctgac tgggcatcca tcaatctctg
2401 tgttgtcatc tgtaagaagt gtgcaggaca gcatagatct ttaggaccaa aagattccaa
2461 ggttagaagt ctaaaaatgg atgctagcat ttggagcaat gaactcatcg agctttttat
2521 tgtcattgga aacaaaagag caaatgactt ttgggctggt aatcttcaaa aggatgaaga
2581 attacatatg gactcaccag tagaaaagag aaaaaacttt attactcaga aatataaaga
2641 aggaaaattc agaaaaactc ttttggcatc tctcaccaaa gaagaattaa ataaggctct
2701 atgtgctgct gtagtgaaac cggatgttct agaaacaatg gctttgctgt tcagtggagc
2761 agatgtcatg tgtgccaccg gagaccccgt gcatagcacc ccctatctgc tagccaagaa
2821 agctgggcaa agtctgcaaa tggaatttct ctaccataac aaattctcag atttccctca
2881 acatgatatt cattccgagg gtgtattaag tcaagagtct tcccagtcca cattcctctg
2941 tgacttttta tatcaagctc cttctgctgc ttctaaactc tcttcagaga aaaaactgct
3001 tgaagagaca aataaaaaat ggtgtgtttt ggaaggaggc ttcttgagtt actatgaaaa
3061 tgataagtct accacaccta atggcaccat taatatcaat gaagttatct gcctggctat
3121 acacaaagag gacttctatt taaatactgg gcccatcttt atctttgaga tctacttacc
3181 ctccgaacgt gtgtttttat ttggagctga aacatctcaa gctcaaagaa aatggacaga
3241 ggcaatagcc aagcattttg ttcccttatt tgctgaaaac ttaacagaag ctgactatga
3301 tttgattggt caactcttct acaaagactg ccatgccctg gatcagtgga gaaaaggctg
3361 gtttgctatg gacaaatcca gcttgcattt ttgccttcaa atgcaagaag ttcagggaga
3421 tagaatgcac ttaagaagac tgcaagagct aacaatcagc acaatggttc aaaatgggga
3481 aaaactggat gttttactct tggtagaaaa agggagaaca ttatacatcc atgggcatac
3541 caagttggat ttcacagtct ggcatactgc aattgaaaaa gcagcaggta cagatggtaa
3601 tgctttacaa gatcagcagc tcagcaaaaa tgacgttccc attatagtga acagctgtat
3661 agcatttgtt acacagtatg gtttaggatg caaatatatc tatcaaaaga atggtgatcc
3721 tttgcatata agtgaactcc tggagagttt caaaaaggat gcaagaagct ttaaattgag
3781 ggctggaaaa catcagcttg aagatgtgac ggctgtgttg aaaagttttc tctctgacat
3841 tgatgatgca ctgcttacta aggagctcta cccatattgg atctctgctt tagatacgca
3901 agatgacaag gaaagaatta aaaaatatgg agcatttata cgttctcttc caggggtcaa
3961 ccgagcaaca ctagcagcta tcattgaaca cctgtatagg gttcagaaat gctcagaaat
4021 caatcacatg aatgcccata atttggcctt ggtcttttca tcctgtttgt ttcaaacgaa
4081 gggacaaact agtgaagaag tgaatgtaat tgaggaccta attaataatt atgtagaaat
4141 atttgaggtt aaagaagatc aagtcaaaca aatggacata gaaaatagct ttattaccaa
4201 gtggaaagac acccaagttt cccaggctgg agatttgtta attgaagtat atgtagaaag
4261 gaaggaaccc gactgtagta ttataattcg gatatctcct gtgatggaag cagaagaatt
4321 aactaatgat atattagcga taaaaaatat tattcctaca aaaggtgata tttgggccac
4381 atttgaagtc attgaaaatg aagagctaga gcgtcctctt cactacaagg aaaatgtact
4441 ggagcaggtg cttcggtgga gttcattagc tgaacctggc tctgcttacc tggtggtgaa
4501 gagattctta accgctgaca caattaaaca ctgcagtgac cggagtacac tgggaagcat
4561 caaagaagga atcttgaaaa tcaaagaaga accatccaaa atactatctg gaaataagtt
4621 tcaagaccgg tattttgttt tacgagatgg gtttctcttt ctttacaagg atgtgaagag
4681 tagtaaacat gacaagatgt tttctctcag ttccatgaag ttttatcgtg gagtgaaaaa
4741 gaaaatgaag cctccaacaa gctggggatt gaccgcatat tctgagaaac atcactggca
4801 cctgtgttgt gatagttcac aaactcagac ggagtggatg accagtatct ttattgccca
4861 gcatgaatat gatatatggc caccagctgg aaaggaacga aaacgttcaa taaccaaaaa
4921 tcccaaaatt ggaggtttgc ctctgattcc tatacagcat gaggggaatg caaccttggc
4981 ccggaaaaat attgagagtg caagagcaga acttgaaagg ctgcggctca gtgaaaagtg
5041 tgataaagag tccgtggact ctagcttaaa ggagagagct tccatggtgg cccactgcct
5101 ggagcacaag gacgataaac ttcgaaatcg accccgaaaa catcggagtt tcaactgcct
5161 ggaggacaca gagcctgaag ccccacttgg gcaaccaaaa ggccataaag gcctaaagac
5221 attgaggaag actgaggaca ggaatagcaa agctactttg gactctgatc ataagttacc
5281 atcaagggta attgaagaac ttaatgtggt tctacaacgg tcaagaaccc ttccaaaaga
5341 attacaggat gagcagattt tgaagtagga aataaaatga attgctcccc agattatttt
5401 tttaatattg tatgcaatct ttatgtgtaa ctccaaaact gaactataag ataattcata
5461 agaatttgcc tattgatagg caaatttgtc tatgcttagg catttaagga gcatttaaaa
5521 atatgtatat atgtgactga atgtaagatt aactttattt tggtctgaac aaaccttgta
5581 aagttccatt gtattaacgt gtgtaagaag acattgggtt acttaggtgg tcagtccttt
5641 taaagtagtt gtctgttaag tggtataatt tatgagcaga aatctcaaac tgtactgtat
5701 tgtataaaat gctgtgttta aatgaagcct aagaaactat ctgtaacata ttttgcactt
5761 tgagaaacct tgtatattaa attaccatat gtttttaggt ttacagaagt tctaccttag
5821 ggaaaagaaa gggaagtaaa ttgaaaaagg ggggagaatt tattgtagtg gctgcctaaa
5881 aaccactgga gtttttaaaa gaagcaagga gttaaatgtc ctgcaaaaca aggaagtgag
5941 ctaagattca ttctagttca ctaatgacca gaacttgtca atgagaaacc acttgttaag
6001 aaaaagtcca gtgtttattt ctcaagagta atattcggcc aacagatgta aataatagca
6061 ctagccactc ttattaatat ttatagtgtt agaaaaccag ccacattaca gattcactac
6121 gtttgagctc attgttggtg gctgctaaga ggaaacttac actgcattgg agaggttgtg
6181 tacacaggac ctggcctgga tgctgattgc actgtcattg tatgcaagca ttttgtcttt
6241 tttcagaatt tctgactata cttttggtac gaacaaaatt catcaccaca gggtcctgtt
6301 gttttgtttg atttttagat ttttttaaat tattattaag gttgtaatgt ttttctccga
6361 gttgtcagaa ataactggaa gaatacaata tatggccatt atggagccag gggctagttg
6421 gtggtttact atacatttgg gggctacctg gtcacattta atctaggttt ttttttcttt
6481 ttttaagtaa aggtgtggtc tcttccctgt acttatgaat aaggacaaag ccctattttt
6541 gtttccacat aaagatcagc tactgaattg gtgaatttcc tgacagacaa tgctatctaa
6601 ccatagttca cgttagggga agcatttttc catcagtttc tttaaaattg gattgtctgg
6661 tgagttttga tattaaacat tatgtagcta agtttttttt tttagcattt cttttttatt
6721 tttcaatcta tattcacagg cccatacttc agtcagtcca atcatagtac agtgatgtgg
6781 tggtagatgc tatgaatttc ttcattgtaa aatacggatc atttgtattt tggggtgata
6841 aaatagttca ccatgggtat gagatattta ttctttaaat caaagtaaat tagaattttt
6901 aaaaagcaca aaactgcagg acagtttatg aaataggtgg cactattagg gaatcttcct
6961 ttaaagcaag aaatcatgtt atttagaaag aaaaactaat cttaaacata ctatttctaa
7021 taaatattta tatttttatg aaataaagag gtatgtggaa attaatattt ggtgatgttg
7081 gacagtggaa aagtatctag agtttttacc tgccttatct gaattcttct tgaaacttga
7141 gcttaaactc taatagctgt ttccctttct attctgaaca actgtctcca tttttcaagt
7201 gtgagagata agggctaatg atgacatctc atttattttg agtaaacatt aaaattgttt
7261 tacaagtcta cttg
//