LOCUS AY048580 2940 bp mRNA linear HUM 30-APR-2002
DEFINITION Homo sapiens NIMA-related kinase Nek8 mRNA, complete cds.
ACCESSION AY048580
VERSION AY048580.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2940)
AUTHORS Holland,P.M., Milne,A., Garka,K., Johnson,R.S., Willis,C.,
Sims,J.E., Rauch,C.T., Bird,T.A. and Virca,G.D.
TITLE Purification, cloning, and characterization of Nek8, a novel
NIMA-related kinase, and its candidate substrate Bicd2
JOURNAL J. Biol. Chem. 277 (18), 16229-16240 (2002)
PUBMED 11864968
REFERENCE 2 (bases 1 to 2940)
AUTHORS Holland,P.M., Milne,A., Garka,K., Johnson,R.S., Willis,C.R.,
Sims,J.E., Rauch,C.T., Bird,T.A. and Virca,G.D.
TITLE Direct Submission
JOURNAL Submitted (27-JUL-2001) Immunex Corporation, 51 University St.,
Seattle, WA 98101, USA
FEATURES Location/Qualifiers
source 1..2940
/db_xref="H-InvDB:HIT000083820"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q24.3"
CDS 1..2940
/note="similar to GenBank Accession Number AC007055"
/codon_start=1
/product="NIMA-related kinase Nek8"
/protein_id="AAL05428.1"
/translation="MSVLGEYERHCDSINSDFGSESGGCGDSSPGPSASQGPRAGGGA
AEQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVI
LALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQI
VSAVSCIHKAGILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYM
SPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQ
YSLELIQMVHSCLDQDPEQRPTADELLDRPLLRKRRREMEEKVTLLNAPTKRPRSSTV
TEAPIAVVTSRTSEVYVWGGGKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYT
WVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAF
GSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGE
YGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL
NQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCN
KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL
AMTPTERPHGSDICTSWPRPIFGSLHHVPDLSCRGWHTILIVEKVLNSKTIRSNSSGL
SIGTVFQSSSPGGGGGGGGGEEEDSQQESETPDPSGGFRGTMEADRGMEGLISPTEAM
GNSNGASSSCPGWLRKELENAEFIPMPDSPSPLSAAFSESEKDTLPYEELQGLKVASE
APLEHKPQVEASSPRLNPAVTCAGKGTPLTPPACACSSLQVEVERLQGLVLKCLAEQQ
KLQQENLQIFTQLQKLNKKLEGGQQVGMHSKGTQTAKEEMEMDPKPDLDSDSWCLLGT
DSCRPSL"
BASE COUNT 760 a 672 c 816 g 692 t
ORIGIN
1 atgtcggtgc tgggcgagta cgagcgacac tgcgattcca tcaactcgga ctttgggagc
61 gagtccgggg gttgcgggga ctcgagtccg gggcctagcg ccagtcaggg gccgcgagcc
121 ggcggcggcg cggcggagca ggaggaactg cactacatcc ccatccgcgt cctgggccgc
181 ggcgccttcg gggaagccac gctgtaccgc cgcaccgagg atgactcact ggttgtgtgg
241 aaggaagtcg atttgacccg gctgtctgag aaggaacgtc gtgatgcctt gaatgagatt
301 gttattctgg cactgctgca gcatgacaac attattgcct actacaatca cttcatggac
361 aataccacgc tgctgattga gctggaatat tgtaatggag ggaacctgta tgacaaaatc
421 cttcgtcaga aggacaagtt gtttgaggaa gagatggtgg tgtggtacct atttcagatt
481 gtttcagcag tgagctgcat ccataaagct ggaatccttc atagagatat aaagacatta
541 aatatttttc tgaccaaggc aaacctgata aaacttggag attatggcct agcaaagaaa
601 cttaattctg agtattccat ggctgagacg cttgtgggaa ccccatatta catgtctcca
661 gagctctgtc aaggagtaaa gtacaatttc aagtctgata tctgggcagt tggctgcgtc
721 atttttgaac tgcttacctt aaagaggacg tttgatgcta caaacccact taacctgtgt
781 gtgaagatcg tgcaaggaat tcgggccatg gaagttgact ctagccagta ctctttggaa
841 ttgatccaaa tggttcattc gtgccttgac caggatcctg agcagagacc tactgcagat
901 gaacttctag atcgccctct tctcaggaaa cgcaggagag agatggagga aaaagtcact
961 ctgcttaatg cacctacaaa gagaccaagg tcaagcactg tgactgaagc acccattgct
1021 gtagtaacat cacgaaccag tgaagtctat gtttggggtg gtggaaaatc caccccccag
1081 aaactggatg ttatcaagag tggctgtagt gcccggcagg tctgtgcagg gaatacccac
1141 tttgctgtgg tcacagtgga gaaggaactg tacacttggg tgaacatgca aggaggcact
1201 aaactccatg gtcagctggg ccatggagac aaagcctcct atcgacagcc aaagcatgtg
1261 gaaaagttgc aaggcaaagc tatccatcag gtgtcatgtg gtgatgattt cactgtctgt
1321 gtgactgatg agggtcagct ctatgccttc ggatcagatt attatggctg catgggggtg
1381 gacaaagttg ctggccctga agtgctagaa cccatgcagc tgaacttctt cctcagcaat
1441 ccagtggagc aggtctcctg tggagataat catgtggtgg ttctgacacg aaacaaggaa
1501 gtctattctt ggggctgtgg cgaatatgga cgactgggtt tggattcaga agaggattat
1561 tatacaccac aaaaggtgga tgttcccaag gccttgatta ttgttgcagt tcaatgtggc
1621 tgtgatggga catttctgtt gacccagtca ggcaaagtgc tggcctgtgg actcaatgaa
1681 ttcaataagc tgggtctgaa tcagtgcatg tcgggaatta tcaaccatga agcataccat
1741 gaagttccct acacaacgtc ctttaccttg gccaaacagt tgtcctttta taagatccgt
1801 accattgccc caggcaagac tcacacagct gctattgatg agcgaggccg gctgctgacc
1861 tttggctgca acaagtgtgg gcagctgggc gttgggaact acaagaagcg tctgggaatc
1921 aacctgttgg ggggacccct tggtgggaag caagtgatca gggtctcctg cggtgatgag
1981 tttaccattg ctgccactga tgataatcac atttttgcct ggggcaatgg tggtaatggc
2041 cgcctggcaa tgacccccac agagagacca catggctctg atatctgtac ctcatggcct
2101 cggcctattt ttggatctct gcatcatgtc ccggacctgt cttgccgtgg atggcatacc
2161 attctcatcg ttgagaaagt attgaattct aagaccatcc gttccaatag cagtggctta
2221 tccattggaa ctgtgtttca gagctctagc ccgggaggag gcggcggggg cggcggtggt
2281 gaagaagagg acagtcagca ggaatctgaa actcctgacc caagtggagg cttccgagga
2341 acaatggaag cagaccgagg aatggaaggt ttaatcagtc ccacagaggc catggggaac
2401 agtaatgggg ccagcagctc ctgtcctggc tggcttcgaa aggagctgga aaatgcagaa
2461 tttatcccca tgcctgacag cccatctcct ctcagtgcag cgttttcaga atctgagaaa
2521 gataccctgc cctatgaaga gctgcaagga ctcaaagtgg cctctgaagc tcctttggaa
2581 cacaaacccc aagtagaagc ctcgtcacct cggctgaatc ctgcagtaac ctgtgctggg
2641 aagggaacac cactgactcc tcctgcgtgt gcgtgcagct ctctgcaggt ggaggttgag
2701 agattgcagg gtctggtgtt aaagtgtctg gctgaacaac agaagctaca gcaagaaaac
2761 ctccagattt ttacccaact gcagaagttg aacaagaaat tagaaggagg gcagcaggtg
2821 gggatgcatt ccaaaggaac tcagacagca aaggaagaga tggaaatgga tccaaagcct
2881 gacttagatt cagattcctg gtgcctcctg ggaacagact cctgtagacc cagcctctag
//