LOCUS AY043361 3479 bp mRNA linear HUM 01-SEP-2001
DEFINITION Homo sapiens WW domain-containing protein 1 mRNA, complete cds.
ACCESSION AY043361
VERSION AY043361.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3479)
AUTHORS Flasza,M., Aslam,H., Poulsom,R., Hanby,A., Gorman,P., Roylance,R.,
Nolan,T., Brady,G., Canfield,A. and Baron,M.
TITLE WWP1, a human homolog of Drosophila suppressor of deltex
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3479)
AUTHORS Flasza,M., Aslam,H., Poulsom,R., Hanby,A., Gorman,P., Roylance,R.,
Nolan,T., Brady,G., Canfield,A. and Baron,M.
TITLE Direct Submission
JOURNAL Submitted (03-JUL-2001) Biological Sciences, University of
Manchester, Stopford Building, Oxford Rd., Manchester M13 9PT, UK
FEATURES Location/Qualifiers
source 1..3479
/db_xref="H-InvDB:HIT000083748"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q21"
CDS 86..2854
/note="WWP1; Nedd4 family E3 ubiquitin ligase; suppressor
of deltex related protein 1 (hSDRP1)"
/codon_start=1
/product="WW domain-containing protein 1"
/protein_id="AAK94668.1"
/translation="MATASPRSDTSNNHSGRLQLQVTVSSAKLKRKKNWFGTAIYTEV
VVDGEITKTAKSSSSSNPKWDEQLTVNVTPQTTLEFQVWSHRTLKADALLGKATIDLK
QALLIHNRKLERVKEQLKLSLENKNGIAQTGELTVVLDGLVIEQENITNCSSSPTIEI
QENGDALHENGEPSARTTARLAVEGTNGIDNHVPTSTLVQNSCCSYVVNGDNTPSSPS
QVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTST
TVEDPPVQEILTSSENNECIPSTSAELESEARSILEPDTSNSRSSSAFEAAKSRQPDG
CMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVD
DRRRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAA
ENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLQNEEPLPEGWEIRYTR
EGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERGFRWKLAHFRYLCQSNALPSH
VKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVL
NPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPF
YKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLK
LGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELE
VMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRL
PLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIE
ETEGFGQE"
misc_feature 137..508
/note="Region: C2 domain"
misc_feature 1130..1222
/note="Region: WW domain"
misc_feature 1223..1333
/note="Region: WW domain"
misc_feature 1451..1543
/note="Region: WW domain"
misc_feature 1571..1666
/note="Region: WW domain"
misc_feature 1787..2851
/note="Region: HECT domain"
BASE COUNT 1152 a 632 c 721 g 974 t
ORIGIN
1 tgaaagaggg aatcgtgtct tactcatctt tgtatcccca gtgtctagca gttcctgata
61 catagtttta gctgaatttt gggacatggc cactgcttca ccaaggtctg atactagtaa
121 taaccacagt ggaaggttgc agttacaggt aactgtttct agtgccaaac ttaaaagaaa
181 aaagaactgg ttcggaacag caatatatac agaagtagtt gtagatggag aaattacgaa
241 aacagcaaaa tccagtagtt cttctaatcc aaaatgggat gaacagctaa ctgtaaatgt
301 tacgccacag actacattgg aatttcaagt ttggagccat cgcactttaa aagcagatgc
361 tttattagga aaagcaacga tagatttgaa acaagctctg ttgatacaca atagaaaatt
421 ggaaagagtg aaagaacaat taaaactttc cttggaaaac aagaatggca tagcacaaac
481 tggtgaattg acagttgtgc ttgatggatt ggtgattgag caagaaaata taacaaactg
541 cagctcatct ccaaccatag aaatacagga aaatggtgat gccttacatg aaaatggaga
601 gccttcagca aggacaactg ccaggttggc tgttgaaggc acgaatggaa tagataatca
661 tgtacctaca agcactctag tccaaaactc atgctgctcg tatgtagtta atggagacaa
721 cacaccttca tctccgtctc aggttgctgc cagacccaaa aatacaccag ctccaaaacc
781 actcgcatct gagcctgccg atgacactgt taatggagaa tcatcctcat ttgcaccaac
841 tgataatgcg tctgtcacgg gtactccagt agtgtctgaa gaaaatgcct tgtctccaaa
901 ttgcactagt actactgttg aagatcctcc agttcaagaa atactgactt cctcagaaaa
961 caatgaatgt attccttcta ccagtgcaga attggaatct gaagctagaa gtatattaga
1021 gcctgacacc tctaattcta gaagtagttc tgcttttgaa gcagccaaat caagacagcc
1081 agatgggtgt atggatcctg tacggcagca gtctgggaat gccaacacag aaaccttgcc
1141 atcagggtgg gaacaaagaa aagatcctca tggtagaacc tattatgtgg atcataatac
1201 tcgaactacc acatgggaga gaccacaacc tttacctcca ggttgggaaa gaagagttga
1261 tgatcgtaga agagtttatt atgtggatca taacaccaga acaacaacgt ggcagcggcc
1321 taccatggaa tctgtccgaa attttgaaca gtggcaatct cagcggaacc aattgcaggg
1381 agctatgcaa cagtttaacc aacgatacct ctattcggct tcaatgttag ctgcagaaaa
1441 tgacccttat ggacctttgc caccaggctg ggaaaaaaga gtggattcaa cagacagggt
1501 ttactttgtg aatcataaca caaaaacaac ccagtgggaa gatccaagaa ctcaaggctt
1561 acagaatgaa gaacccctgc cagaaggctg ggaaattaga tatactcgtg aaggtgtaag
1621 gtactttgtt gatcataaca caagaacaac aacattcaaa gatcctcgca atgggaagtc
1681 atctgtaact aaaggtggtc cacaaattgc ttatgaacgc ggctttaggt ggaagcttgc
1741 tcacttccgt tatttgtgcc agtctaatgc actacctagt catgtaaaga tcaatgtgtc
1801 ccggcagaca ttgtttgaag attccttcca acagattatg gcattaaaac cctatgactt
1861 gaggaggcgc ttatatgtaa tatttagagg agaagaagga cttgattatg gtggcctagc
1921 gagagaatgg tttttcttgc tttcacatga agttttgaac ccaatgtatt gcttatttga
1981 gtatgcgggc aagaacaact attgtctgca gataaatcca gcatcaacca ttaatccaga
2041 ccatctttca tacttctgtt tcattggtcg ttttattgcc atggcactat ttcatggaaa
2101 gtttatcgat actggtttct ctttaccatt ctacaagcgt atgttaagta aaaaacttac
2161 tattaaggat ttggaatcta ttgatactga attttataac tcccttatct ggataagaga
2221 taacaacatt gaagaatgtg gcttagaaat gtacttttct gttgacatgg agattttggg
2281 aaaagttact tcacatgacc tgaagttggg aggttccaat attctggtga ctgaggagaa
2341 caaagatgaa tatattggtt taatgacaga atggcgtttt tctcgaggag tacaagaaca
2401 gaccaaagct ttccttgatg gttttaatga agttgttcct cttcagtggc tacagtactt
2461 cgatgaaaaa gaattagagg ttatgttgtg tggcatgcag gaggttgact tggcagattg
2521 gcagagaaat actgtttatc gacattatac aagaaacagc aagcaaatca tttggttttg
2581 gcagtttgtg aaagagacag acaatgaagt aagaatgcga ctattgcagt tcgtcactgg
2641 aacctgccgt ttacctctag gaggatttgc tgagctcatg ggaagtaatg ggcctcaaaa
2701 gttttgcatt gaaaaagttg gcaaagacac ttggttacca agaagccata catgttttaa
2761 tcgcttggat ctaccaccat ataagagtta tgaacaacta aaggaaaaac ttctttttgc
2821 aatagaagag acagagggat ttggacaaga atgaatgtgg cttcttattt tggaggagct
2881 cttgcattta aataccccag ccaagaaaaa ttgcacagat agtgtatata agctgttcat
2941 tctgtacagt gaattttccg aacctctcaa agtatgtttt ccgttcttcc acagaaatat
3001 gcaaaacagt tcatcctttt ctactttatt tattgttccc ttgaaatgac tgaccaggaa
3061 aaagatcatc cttaaatttt gaagcaagtg agagacttta ttaaaaatac atatatatct
3121 atataaacat atatgatagt ggctctagtt ttatagagct ccaagtgtat taaacatgac
3181 agccattcat tcataaagat ctggatttgc tttaccttgt taatattatc taggggaaaa
3241 agtgcaaatt gctccatgtt cttctctccc ttatgtaaca tctcctgagg gtgtttagtt
3301 gcatggctgt tcagaaaggt attaagggct taggccaaat cttactttga gtatgttaaa
3361 aaaaaaaaaa tgctgctggc ttttctgaag acaggtgctt gaacttgtca gtttgtttta
3421 aataaataca atagttgaaa atttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//