LOCUS AY040871 2867 bp mRNA linear HUM 04-SEP-2001
DEFINITION Homo sapiens cell division autoantigen 1 nucleolar protein mRNA,
complete cds.
ACCESSION AY040871
VERSION AY040871.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2867)
AUTHORS Chai,Z., Sarcevic,B., Mawson,A. and Toh,B.H.
TITLE SET-related cell division autoantigen-1 (CDA1) arrests cell growth
JOURNAL J. Biol. Chem. 276 (36), 33665-33674 (2001)
PUBMED 11395479
REFERENCE 2 (bases 1 to 2867)
AUTHORS Chai,Z. and Toh,B.-H.
TITLE Direct Submission
JOURNAL Submitted (18-JUN-2001) Molecular Hypertension Laboratory, Baker
Medical Research Institute, Commercial Rd, P.O. Box 6492,
Melbourne, VIC 8008, Australia
FEATURES Location/Qualifiers
source 1..2867
/db_xref="H-InvDB:HIT000083635"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
misc_feature 1..500
/note="GC-rich region"
CDS 129..2210
/note="CDA1; cell growth/division inhibitor; up-regulated
CDA1 results in cell growth arrest at multiple cell cycle
stages; contains four nuclear localization signals,
N-terminal proline rich domain and C-terminal acidic tail;
contains regions similar to SET, NAP and TSPY"
/codon_start=1
/product="cell division autoantigen 1 nucleolar protein"
/protein_id="AAK72407.1"
/translation="MDRPDEGPPAKTRRLSSSESPQRDPPPPPPPPPLLRLPLPPPQQ
RPRLQEETEAAQVLADMRGVGLGPALPPPPPYVILEEGGIRAYFTLGAECPGWDSTIE
SGYGEAPPPTESLEALPTPEASGGSLEIDFQVVQSSSFGGEGALETCSAVGWAPQRLV
DPKSKEEAIIIVEDEDEDERESMRSSRRRRRRRRRKQRKVKRESRERNAERMESILQA
LEDIQLDLEAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRI
SILINRRDEDIFRYLTNLQVQDLRHISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGR
LVSHSTPIRWHRGQEPQARRHGNQDASHSFFSWFSNHSLPEADRIAEIIKNDLWVNPL
RYYLRERGSRIKRKKQEMKKRKTRGRCEVVIMEDAPDYYAVEDIFSEISDIDETIHDI
KISDFMETTDYFETTDNEITDINENICDSENPDHNEVPNNETTDNNESADDHETTDNN
ESADDNNENPEDNNKNTDDNEENPNNNENTYGNNFFKGGFWGSHGNNQDSSDSDNEAD
EASDDEDNDGNEGDNEGSDDDGNEGDNEGSDDDDRDIEYYEKVIEDFDKDQADYEDVI
EIISDESVEEEGIEEGIQQDEDIYEEGNYEEEGSEDVWEEGEDSDDSDLEDVLQVPNG
WANPGKRGKTG"
BASE COUNT 760 a 755 c 817 g 535 t
ORIGIN
1 cgaggtggtg aggagagctg gttgcgtgag tctcctcagc tctgcttacc ggtgcgacta
61 gcggcagcga cgcggctaaa agcgaagggg cgagtgcgag tcccctgagc tgtacgaacg
121 cggtcgccat ggaccgccca gatgaggggc ctccggccaa gacccgccgc ctgagcagct
181 ccgagtctcc acagcgcgac ccgcccccgc cgccgccgcc gccgccgctc ctccgactgc
241 cgctgcctcc accccagcag cgcccgaggc tccaggagga aacggaggcg gcacaggtgc
301 tggccgatat gaggggggtg ggactgggcc ccgcgctgcc cccgccgcct ccctatgtca
361 ttctcgagga gggggggatc cgcgcatact tcacgctcgg tgctgagtgt cccggctggg
421 attctaccat cgagtcgggg tatggggagg cgcccccgcc cacggagagc ctggaagcac
481 tccccactcc tgaggcctcg ggggggagcc tggaaatcga ttttcaggtt gtacagtcga
541 gcagttttgg tggagagggg gccctagaaa cctgtagcgc agtggggtgg gcgccccaga
601 ggttagttga cccgaagagc aaggaagagg cgatcatcat agtggaggat gaggatgagg
661 atgagcggga gagtatgagg agcagcagga ggcggcggcg gcggcggagg aggaagcaga
721 ggaaggtgaa gagggaaagc agagagagaa atgccgagag gatggagagc atcctgcagg
781 cactggagga tattcagctg gatctggagg cagtgaacat caaggcaggc aaagccttcc
841 tgcgtctcaa gcgcaagttc atccagatgc gaagaccctt cctggagcgc agagacctca
901 tcatccagca tatcccaggc ttctgggtca aagcattcct caaccacccc agaatttcaa
961 ttttgatcaa ccgacgtgat gaagacattt tccgctactt gaccaatctg caggtacagg
1021 atctcagaca tatctccatg ggctacaaaa tgaagctgta cttccagact aacccctact
1081 tcacaaacat ggtgattgtc aaggagttcc agcgcaaccg ctcaggccgg ctggtgtctc
1141 actcaacccc aatccgctgg caccggggcc aggaacccca ggcccgtcgt cacgggaacc
1201 aggatgcgag ccacagcttt ttcagctggt tctcaaacca tagcctccca gaggctgaca
1261 ggattgctga gattatcaag aatgatctgt gggttaaccc tctacgctac tacctgagag
1321 aaaggggctc caggataaag agaaagaagc aagaaatgaa gaaacgtaaa accaggggca
1381 gatgtgaggt ggtgatcatg gaagacgccc ctgactatta tgcagtggaa gacattttca
1441 gcgagatctc agacattgat gagacaattc atgacatcaa gatctctgac ttcatggaga
1501 ccaccgacta cttcgagacc actgacaatg agataactga catcaatgag aacatctgcg
1561 acagcgagaa tcctgaccac aatgaggtcc ccaacaacga gaccactgat aacaacgaga
1621 gcgctgatga ccacgaaacc actgacaaca atgagagtgc agatgacaac aacgagaatc
1681 ctgaagacaa taacaagaac actgatgaca acgaagagaa ccctaacaac aacgagaaca
1741 cttacggcaa caacttcttc aaaggtggct tctggggcag ccatggcaac aaccaggaca
1801 gcagcgacag tgacaatgaa gcagatgagg ccagtgatga tgaagataat gatggcaacg
1861 aaggtgacaa tgagggcagt gatgatgatg gcaatgaagg tgacaatgaa ggcagcgatg
1921 atgacgacag agacattgag tactatgaga aagttattga agactttgac aaggatcagg
1981 ctgactacga ggacgtgata gagatcatct cagacgaatc agtggaagaa gagggcattg
2041 aggaaggcat ccagcaagat gaggacatct atgaggaagg aaactatgag gaggaaggaa
2101 gtgaagatgt ctgggaagaa ggggaagatt cggacgactc tgacctagag gatgtgcttc
2161 aggtcccaaa cggttgggcc aatccgggga agagggggaa aaccggataa gggttttccc
2221 cttttgggga tcacctctct gtatccccca cccactatcc catttgccct cctcctcagc
2281 tagggccacg cggccccaca ttgcacttct ggggggtgac cgacttcgta cacgggttta
2341 aagtttattt ttatggttta gtcattgcag agttcttatt ttggggggag ggaaaggggg
2401 ctagtcccct tcttttggcc ctccgccccc gcaggcttct gtgtgctgct aactgtattt
2461 attgtgatgc cttggtcagg gcccctctac ccacttctcc cagtcagttg tggccccagc
2521 ccctctccct gtgctgtgtg gagtggacac cctgaccccc gaagcgggga gggccgctgt
2581 ggccttcgtc acagccgcgc agtgcccatg gaggcgctgc tgccaccttc ctctcccaag
2641 ttctttctcc atccctctcc tcttcccgcc gcgccgctag cccgcctcgg tgtctatgca
2701 aggccgcttc gccattgcgg tattctttgc ggtattcttg tccccgtccc ccagaaggct
2761 cgcctctccc cgtggaccct gttaatccca ataaaattct gagcaagttc aaaaaaaaaa
2821 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//