LOCUS AY040220 5168 bp mRNA linear HUM 01-AUG-2001
DEFINITION Homo sapiens ATP-binding cassette transporter sub-family C member
12 (ABCC12) mRNA, complete cds.
ACCESSION AY040220
VERSION AY040220.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5168)
AUTHORS Tammur,J., Prades,C., Arnould,I., Rzhetsky,A., Hutchinson,A.,
Adachi,M., Schuetz,J.D., Swoboda,K.J., Ptacek,L.J., Rosier,M.,
Dean,M. and Allikmets,R.
TITLE Two new genes from the human ATP-binding cassette transporter
superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome
16q12
JOURNAL Gene 273 (1), 89-96 (2001)
PUBMED 11483364
REFERENCE 2 (bases 1 to 5168)
AUTHORS Tammur,J., Prades,C., Arnould,I., Rosier,M., Dean,M. and
Allikmets,R.
TITLE Direct Submission
JOURNAL Submitted (14-JUN-2001) Ophthalmology, Columbia University, Eye
Research Addition, 630 West 168th Street, New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..5168
/db_xref="H-InvDB:HIT000083606"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q12"
/tissue_type="testis"
gene 1..5168
/gene="ABCC12"
CDS 347..4426
/gene="ABCC12"
/note="CFTR/MRP"
/codon_start=1
/product="ATP-binding cassette transporter sub-family C
member 12"
/protein_id="AAK76740.1"
/translation="MVGEGPYLISDLDQRGRRRSFAERYDPSLKTMIPVRPCARLAPN
PVDDAGLLSFATFSWLTPVMVKGYRQRLTVDTLPPLSTYDSSDTNAKRFRVLWDEEVA
RVGPEKASLSHVVWKFQRTRVLMDIVANILCIIMAAIGPVILIHQILQQTERTSGKVW
VGIGLCIALFATEFTKVFFWALAWAINYRTAIRLKVALSTLVFENLVSFKTLTHISVG
EVLNILSSDSYSLFEAALFCPLPATIPILMVFCAAYAFFILGPTALIGISVYVIFIPV
QMFMAKLNSAFRRSAILVTDKRVQTMNEFLTCIRLIKMYAWEKSFTNTIQDIRRRERK
LLEKAGFVQSGNSALAPIVSTIAIVLTLSCHILLRRKLTAPVAFSVIAMFNVMKFSIA
ILPFSIKAMAEANVSLRRMKKILIDKSPPSYITQPEDPDTVLLLANATLTWEHEASRK
STPKKLQNQKRHLCKKQRSEAYSERSPPAKGATGPEEQSDSLKSVLHSISFVVRKGKI
LGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGTLAYVSQQAWIFHGNVRENILFGEK
YDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRISLARAVYSDRQLY
LLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQLQFLESCDEVILLEDGEICEK
GTHKELMEERGRYAKLIHNLRGLQFKDPEHLYNAAMVEAFKESPAEREEDAGIIVLAP
GNEKDEGKESETGSEFVDTKVPEHQLIQTESPQEGTVTWKTYHTYIKASGGYLLSLFT
VFLFLLMIGSAAFSNWWLGLWLDKGSRMTCGPQGNRTMCEVGAVLADIGQHVYQWVYT
ASMVFMLVFGVTKGFVFTKTTLMASSSLHDTVFDKILKSPMSFFDTTPTGRLMNRFSK
DMDELDVRLPFHAENFLQQFFMVVFILVILAAVFPAVLLVVASLAVGFFILLRIFHRG
VQELKKVENVSRSPWFTHITSSMQGLGIIHAYGKKESCITYHLLYFNCALRWFALRMD
VLMNILTFTVALLVTLSFSSISTSSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSVE
LLREYISTCVPECTHPLKVGTCPKDWPSCGEITFRDYQMRYRDNTPLVLDSLNLNIQS
GQTVGIVGRTGSGKSSLGMALFRLVEPASGTIFIDEVDICILSLEDLRTKLTVIPQDP
VLFVGTVRYNLDPFESHTDEMLWQVLERTFMRDTIMKLPEKLQAEVTENGENFSVGER
QLLCVARALLRNSKIILLDEATASMDSKTDTLVQNTIKDAFKGCTVLTIAHRLNTVLN
CDHVLVMENGKVIEFDKPEVLAEKPDSAFAMLLAAEVRL"
BASE COUNT 1341 a 1278 c 1284 g 1265 t
ORIGIN
1 gccttggtca ttggaccggc tcccaaccaa aaccacacca tagggttttc tgctcttggc
61 caacccaaca tgagaaaaga ggaattaaat ggtcctacta ataagaaagc ctcagcgtag
121 cattaaggga cgtagcaggt cttctggcca cactccccta caaatgtgga aagctcattg
181 gtgaaaacag ttctcagggg tcaaagcaaa ggaactgatc tgggtaaagt agaggctgcc
241 tgatcccaat cagacatcct cacctctcaa taacctttgc catttctctg ccatagagtg
301 aaagtgtccc caggccaaaa gcccagggct ccaggctgcc atcaggatgg tgggtgaagg
361 accctacctt atctcagatc tggaccagcg aggccggcgg agatcctttg cagaaagata
421 tgaccccagc ctgaagacca tgatcccagt gcgaccctgt gcaaggttag cacccaaccc
481 ggtggatgat gccgggctac tctccttcgc cacattttcc tggctcacgc cggtgatggt
541 gaaaggctac cggcaaaggc tgaccgtaga caccctgccc ccattgtcga catatgactc
601 atctgacacc aatgccaaaa gatttcgagt cctttgggat gaagaggtag caagggtggg
661 tcctgagaag gcctctctga gccacgtggt gtggaaattc cagaggacac gcgtgttgat
721 ggacatcgtg gccaacatcc tgtgcatcat catggcagcc atagggccgg tgattctcat
781 tcaccaaatc ctccagcaga ctgagaggac ctctgggaaa gtctgggttg gcattggact
841 gtgcatagcc ctttttgcca ccgagtttac caaagtcttc ttttgggccc ttgcctgggc
901 catcaactac cgcacggcca tccggttgaa ggtggcgctc tccaccttgg tttttgaaaa
961 cctagtgtcc ttcaagacat tgacccacat ctctgttggc gaggtgctca atatactgtc
1021 aagtgatagc tattctttgt ttgaagctgc cttgttttgt cctttgccag ccaccatccc
1081 gatcctaatg gtcttttgtg cggcgtacgc ctttttcatt ctggggccca cagctctcat
1141 cgggatatca gtgtatgtca tattcatacc cgtccagatg tttatggcca agctcaattc
1201 agctttccga aggtcagcaa ttttggtgac agacaagcga gttcagacaa tgaatgagtt
1261 tctgacctgc atcaggctga tcaaaatgta tgcctgggag aaatctttta ccaacactat
1321 ccaagatata agaaggaggg aaagaaaatt actggaaaaa gctggatttg tccaaagtgg
1381 aaactctgcc ctggccccca tcgtgtccac catagccatc gtgctgacat tatcctgcca
1441 catcctcctg agacgcaaac tcaccgcacc cgtggcattt agtgtgattg ccatgtttaa
1501 tgtaatgaag ttttccattg caatcttgcc cttctccatc aaagcaatgg ctgaagcgaa
1561 tgtctctcta aggagaatga agaaaattct catagataaa agccccccat cttacatcac
1621 ccaaccagaa gacccagata ctgtcttgct tttagcaaat gccaccttga catgggagca
1681 tgaagccagc aggaaaagta ccccaaagaa attgcagaac cagaaaaggc atttatgcaa
1741 gaaacagagg tcagaggcat acagtgagag gagtccacca gccaagggag ccactggccc
1801 agaggagcaa agtgacagcc tcaaatcggt tctgcacagc ataagctttg tggtgagaaa
1861 ggggaagatc ttgggaatat gtgggaatgt gggaagtgga aagagctccc tccttgcagc
1921 tctcctagga cagatgcagc tgcagaaagg ggtggtggca gtcaatggaa ctttggccta
1981 cgtttcacag caggcatgga tctttcatgg aaatgtgaga gaaaacatac tctttggaga
2041 aaagtatgat caccaaaggt atcagcacac agtccgcgtc tgtggcctcc agaaggacct
2101 gagcaacctc ccctatggag acctgactga gattggggag cggggcctca acctctctgg
2161 ggggcagagg cagaggatta gcctggcccg cgctgtctac tccgaccgtc agctctacct
2221 gctggacgac cccctgtcgg ccgtggacgc ccacgtgggg aagcacgtct ttgaggagtg
2281 cattaagaag acgctcaggg gaaagacagt cgtcctggtg acccaccagc tacagttctt
2341 agagtcttgt gatgaagtta ttttattaga agatggagag atttgtgaaa agggaaccca
2401 caaggagtta atggaggaga gagggcgcta tgcaaaactg attcacaacc tgcgaggatt
2461 gcagttcaag gatcctgaac acctttacaa tgcagcaatg gtggaagcct tcaaggagag
2521 ccctgctgag agagaggaag atgctggtat aatcgttttg gctccaggaa atgagaaaga
2581 tgaaggaaaa gaatctgaaa caggctcaga atttgtagac acaaaagttc ctgagcacca
2641 gctcatccag actgaatccc cccaggaagg aaccgtgacc tggaaaacat atcacacgta
2701 cattaaggct tctggagggt acctcctttc tctcttcact gtgttcctct tcctcctgat
2761 gattggcagc gctgccttca gcaactggtg gctgggtctc tggttggaca agggctcacg
2821 gatgacctgt gggccccagg gcaacaggac catgtgtgag gtcggcgcgg tgctggcaga
2881 catcggtcag catgtgtacc agtgggtgta cactgcaagc atggtgttca tgctggtgtt
2941 tggcgtcacc aaaggcttcg tcttcaccaa gaccacactg atggcatcct cctctctgca
3001 tgacacggtg tttgataaga tcttaaagag cccaatgagt ttctttgaca cgactcccac
3061 tggcaggcta atgaaccgtt tttccaagga tatggacgag ctggatgtga ggctgccgtt
3121 tcacgcagag aactttctgc agcagttttt tatggtggtg tttattctcg tgatcttggc
3181 tgctgtgttt cctgctgtcc ttttagtcgt ggccagcctt gctgtaggct tcttcattct
3241 gttacgcatt ttccacagag gagtccagga gctcaagaag gtggagaatg tcagccggtc
3301 accctggttc acccacatca cctcctccat gcagggcctg ggcatcattc acgcctatgg
3361 caagaaggag agctgcatca cctatcacct cctctacttt aactgtgctc tcaggtggtt
3421 tgcgctgaga atggatgtcc tcatgaacat ccttaccttc actgtggcct tgttggtgac
3481 cctgagtttc tcctccatca gtacttcatc caaaggcctg tcattgtcat acatcatcca
3541 gctgagcgga ctgctccaag tgtgtgtgcg aacgggaaca gagacgcaag ccaaattcac
3601 ctccgtggag ctgctcaggg aatacatttc gacctgtgtt cctgaatgca ctcatcccct
3661 caaagtgggg acctgtccca aggactggcc cagctgtggg gagatcacct tcagagacta
3721 tcagatgaga tacagagaca acacccccct tgttctcgac agcctgaact tgaacataca
3781 aagtgggcag acagtcggga ttgttggaag aacaggttcc ggaaagtcat cgttaggaat
3841 ggctttgttt cgtctggtgg agccagccag tggcacaatc tttattgatg aggtggatat
3901 ctgcattctc agcttggaag acctcagaac caagctgact gtgatcccac aggatcctgt
3961 cctgtttgta ggtacagtaa ggtacaactt ggatcccttt gagagtcaca ccgatgagat
4021 gctctggcag gttctggaga gaacattcat gagagacaca ataatgaaac tcccagaaaa
4081 attacaggca gaagtcacag aaaatggaga aaacttctca gtaggggaac gtcagctgct
4141 ttgtgtggcc cgagctcttc tccgtaattc aaagatcatt ctccttgatg aagccaccgc
4201 ctctatggac tccaagactg acaccctggt tcagaacacc atcaaagatg ccttcaaggg
4261 ctgcactgtg ctgaccatcg cccaccgcct caacacagtt ctcaactgcg atcacgtcct
4321 ggttatggaa aatgggaagg tgattgagtt tgacaagcct gaagtccttg cagagaagcc
4381 agattctgca tttgcgatgt tactagcagc agaagtcaga ttgtagaggt cctggcggct
4441 gattctagag gaggaagagg ctctgtgaga tgaataggag gagtcttcag gaggaggggc
4501 tgtcctctcc gcaggcagcc ctggtcttca gcccctccca tccacggagt gagctggggc
4561 tgaagttgtc cccactgcca tactcagtcc atgtcacccc acttggtggg cttggggttg
4621 gttctgggtg gtgaaccggg gcagacccag ctaatggatt aaaaaactgc ccttcacctc
4681 ccaaatcccc aagggttcct catgtgtttt caccaaaacc accccagtgc ctgagattga
4741 aaatattgta actttcagtt agaaatcagc cacaataaac aacatgggaa aatgccttag
4801 gatggagttt gcaaggtttc cttgcccatt atcagaagga aaaagagcag aattttcttc
4861 tcgtttaacc ccactcactt ccatcttgac tgggtgacaa gtggtaatga cacagatttg
4921 tagcgtgaaa gactgaatac agtgtttggc caaaaatttt tttaaaaatc atattatatg
4981 tttcaattga tctgttagaa taaccaagaa aacaaaatgc tggagtttct ctataaatga
5041 cacttttata tcttctttat tcgtcgttaa aacgcggtag gaaattaccc tgaaatgtcg
5101 ccttgcaatt atttcactga agatattcca atttccatac tatttcctcc aatagaccct
5161 tgttgcct
//