LOCUS AY036974 4466 bp mRNA linear HUM 01-DEC-2002
DEFINITION Homo sapiens nucleic acid helicase DDXx mRNA, complete cds.
ACCESSION AY036974
VERSION AY036974.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4466)
AUTHORS Abdelhaleem,M.M.
TITLE Identification of a new member of the DDx subfamily of helicases
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4466)
AUTHORS Abdelhaleem,M.M.
TITLE Direct Submission
JOURNAL Submitted (29-MAY-2001) Pediatric Laboratory Medicine, The Hospital
for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8,
Canada
FEATURES Location/Qualifiers
source 1..4466
/db_xref="H-InvDB:HIT000083526"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q11; between UNG2 and PPAP2A"
CDS 102..4211
/codon_start=1
/product="nucleic acid helicase DDXx"
/protein_id="AAK64516.1"
/translation="MGGKNKKHKAPAAAVVRAAVSASRAKSAEAGIAGEAQSKKPVSR
PATAAAAAAGSREPRVKQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVI
NEHKKQNNDKGMISGRLTAKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALD
WLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKP
KKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE
QAATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATE
GESALNFNLFEKSAAATEEEKGKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLP
KSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVK
GQSVHQLLPPTYRDVWLEWSDAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQ
HSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLL
KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCN
IVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGV
LLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSE
KFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINV
TSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAY
LDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAA
AFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSK
ASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSP
EDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIF
GAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWK
KARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRA
SQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVN
RDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQ
APVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN"
misc_feature 129..254
/note="Region: alanine-rich domain"
misc_feature 732..869
/note="Region: glutamic acid-rich domain"
misc_feature 1236..1349
/note="Region: nuclear localization signal"
misc_feature 1602..1625
/note="Region: glutamine-rich domain"
misc_feature 1974..3080
/note="Region: helicase domain"
BASE COUNT 1499 a 830 c 958 g 1179 t
ORIGIN
1 cagggtggca gccccggagc cggggaatgt gaagagctct cggctgtgca gtggtaccgt
61 cggggcctgg gccgcgaagg atcttctgcc acagctgcaa catgggcggc aagaacaaga
121 aacacaaggc tccagcggcc gcggtggtcc gggccgccgt gtctgcttcc agagccaaat
181 ctgccgaggc tggaattgcc ggggaggccc aaagcaagaa gccagtgtcc aggccggcca
241 ccgctgccgc tgccgctgcc ggctccaggg agccccgtgt caagcaaggt ccaaaaattt
301 atagttttaa ttctacaaat gattctagtg gtcctgcaaa tctggataaa tctattttga
361 aagtggtaat taataacaaa ctagagcaaa gaattattgg agtgatcaat gagcataaaa
421 agcaaaataa tgacaaagga atgatttctg gaagacttac tgccaaaaaa ttgcaggatt
481 tatacatggc tttacaagca ttttcattta agacaaagga cattgaagat gccatgacca
541 atacactctt atatggaggt gaccttcatt ctgccttgga ttggctctgt ttaaaccttt
601 cagatgatgc acttcctgaa ggattcagtc aggaatttga agagcagcaa cctaaaagta
661 ggcctaaatt tcagtctcct caaatacaag ccactatttc acctccattg caacctaaaa
721 caaaaacata tgaagaggac cctaagagta agccaaaaaa ggaagaaaaa aatatggaag
781 taaatatgaa agagtggatt ttacgatatg ctgaacaaca aaatgaagaa gaaaagaatg
841 agaattctaa aagtttagaa gaggaggaaa aatttgaccc taatgaaagg tacttacatc
901 ttgcagcaaa actgctggat gcaaaagaac aagcagctac ctttaaacta gaaaaaaaca
961 agcaaggcca aaaagaggct caggaaaaaa taaggaaatt tcaaagagaa atggaaactt
1021 tagaagacca tccagtattt aacccagcca tgaagatttc acatcaacaa aatgaaagga
1081 aaaagcctcc tgtagccaca gaaggagaaa gtgcattgaa ttttaattta tttgaaaaat
1141 ctgcagctgc tactgaagaa gagaaaggta aaaagaaaga acctcatgat gtaagaaatt
1201 ttgactatac tgctcgaagt tggactggaa aatctcccaa acaatttctg attgattggg
1261 tcaggaagaa tcttcccaag agtccaaatc cttcctttga aaaagttcca gtaggtagat
1321 actggaaatg tagggttagg gtaatcaagt ctgaagatga tgtcctggta gtatgcccta
1381 caatcttaac agaagatggc atgcaagctc agcacctggg agctacttta gccctttacc
1441 gtttagttaa agggcagtca gttcatcagt tacttcctcc cacttaccga gatgtttggc
1501 tggagtggag tgatgcagaa aagaaaaggg aagaattaaa taaaatggaa accaataaac
1561 cacgtgatct ttttattgcc aaacttctga ataaactgaa acagcagcaa cagcagcaac
1621 aacagcattc tgaaaataag agagaaaact ctgaagatcc cgaggaatct tgggaaaatt
1681 tagtttcgga tgaggatttt tctgcactgt ccttggaatc agcaaatgtg gaagatttgg
1741 aacctgttag aaacctcttt agaaagttgc aaagcacacc taagtatcag aaacttctaa
1801 aggaaagaca acagctacct gtatttaaac atcgggactc aattgttgaa actcttaaaa
1861 ggcatcgggt agtggttgtg gcaggtgaaa cagggagtgg taaaagtact caggtaccac
1921 attttctatt ggaagatttg cttctaaatg agtgggaagc aagtaaatgt aacattgtct
1981 gtacccaacc ccgaagaatc tcagcagtta gtttagccaa cagagtatgt gatgaattgg
2041 gctgtgaaaa tggacctgga ggaaggaatt ccttgtgtgg atatcagatc cggatggaat
2101 ctcgagcttg tgaatctacc aggttactct attgtacaac aggggttttg ctaaggaaac
2161 ttcaagaaga tggtcttcta agtaatgtgt ctcatgttat tgtagatgag gttcatgaaa
2221 gaagtgtcca gtcagacttc ctactaatta tcttgaagga aattttacag aaacgttctg
2281 atctacactt gattctaatg agtgccactg tggacagcga aaaattttct acatatttca
2341 cacactgccc cattctcaga atttcaggaa gaagttatcc tgttgaggtt tttcatcttg
2401 aagatataat agaagaaaca ggctttgtac tggaaaaaga ctcagaatat tgtcagaaat
2461 ttctggaaga ggaagaagaa gtaaccatta atgttacaag caaagcaggg ggaataaaaa
2521 aatatcagga atacatccca gttcagactg gagcacatgc tgatttaaat ccattttacc
2581 aaaagtacag cagccgcact cagcatgcta ttctatacat gaatcctcat aaaatcaacc
2641 tggatctcat tttggaactt cttgcatact tagataaaag tccccaattc agaaatattg
2701 aaggagcagt attgatcttt ttaccaggac ttgctcatat tcagcagttg tatgatcttc
2761 tatcaaatga tagaagattt tattctgaac gatataaagt gatagctctg cattctattc
2821 tttcaaccca agatcaagct gcagcattca cacttccccc tccaggagtc aggaagattg
2881 ttttagcaac caatattgca gagacgggta tcactattcc tgatgttgta tttgtaattg
2941 atactggaag aacaaaagaa aataagtacc atgaaagcag tcagatgagt tctttggtgg
3001 agacgtttgt cagtaaagcc agtgctttgc agcgccaggg aagagctggg cgggtcagag
3061 atggcttctg tttccgaatg tacacaagag aaagatttga aggctttatg gattattctg
3121 ttcctgaaat cttacgtgta cctttggagg aattatgcct tcatattatg aaatgtaatc
3181 ttggttctcc tgaagatttc ctctccaaag ccttagatcc tcctcagctc caagtgatca
3241 gcaatgcaat gaatttgctc cgaaaaattg gagcttgtga attaaatgag cctaaactga
3301 ctccgttggg ccaacacctt gcagctttac ctgtgaatgt caagattggc aagatgctta
3361 tttttggtgc catatttggc tgccttgacc cagtggcaac actagctgca gttatgacag
3421 agaagtctcc ttttaccaca ccaattggtc gaaaagatga agcagatctt gcaaaatcag
3481 ctttggccat ggcggattca gaccacctga cgatctacaa tgcatatcta ggatggaaga
3541 aagcacgaca agaaggaggt tatcgttctg aaatcacata ctgccggagg aactttctta
3601 atagaacatc actgttaacc ctagaggatg taaagcagga gttaataaag ttggttaagg
3661 cagcaggatt ttcatcttcc acaacttcta ccagctggga aggaaacaga gcctcacaga
3721 ccctctcatt ccaagaaatt gcccttctta aagctgtact ggtggctgga ctgtatgaca
3781 atgtggggaa gataatctat acaaagtcag tggatgttac agaaaaattg gcttgcattg
3841 tggagacggc ccaaggcaaa gcacaagtac acccatcctc agtaaatcga gatttgcaaa
3901 ctcatggatg gctcttatac caggagaaga taaggtatgc cagagtgtat ttgagagaaa
3961 ctaccctaat aacccctttt ccagttttac tttttggtgg tgatatagaa gttcagcacc
4021 gagaacgtct tctttctatt gatggctgga tctattttca ggcccctgta aagatagctg
4081 tcattttcaa gcagctgaga gttctcattg attcagtttt aagaaaaaag cttgaaaatc
4141 caaagatgtc ccttgaaaat gacaagattc tgcagatcat tacggaattg ataaaaacag
4201 agaataactg aaattcatgg tcaactgctt taaaaattaa gatgaagata cagtcatgaa
4261 attatctgaa aatgggtcat cacattaagt atttcattac ttaaaatgtt ggtactagcc
4321 attaacttaa aggtggtggg aaaaaagcac atactttaaa catgtataat tttctagttc
4381 ctttttaatg atgattattc tgaatgtatt tgccactaca tttacaataa attctttggt
4441 attatgcaaa aaaaaaaaaa aaaaaa
//