LOCUS AY036622 1464 bp mRNA linear HUM 01-JUL-2004
DEFINITION Homo sapiens mu opioid receptor variant MOR-1R (OPRM) mRNA,
complete cds, alternatively spliced.
ACCESSION AY036622
VERSION AY036622.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1464)
AUTHORS Pan,Y.X., Xu,J., Mahurter,L., Xu,M., Gilbert,A.K. and
Pasternak,G.W.
TITLE Identification and characterization of two new human mu opioid
receptor splice variants, hMOR-1O and hMOR-1X
JOURNAL Biochem. Biophys. Res. Commun. 301 (4), 1057-1061 (2003)
PUBMED 12589820
REFERENCE 2 (bases 1 to 1464)
AUTHORS Pan,Y., Xu,J., Xu,M. and Pasternak,G.W.
TITLE Isolation and characterization of a splice variant of human mu
opioid receptor gene (OPRM)
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1464)
AUTHORS Pan,Y., Xu,J., Xu,M. and Pasternak,G.W.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2001) Neurology, Memorial Sloan-Kettering Cancer
Center, 1275 York Ave, New York, NY 10021, USA
FEATURES Location/Qualifiers
source 1..1464
/db_xref="H-InvDB:HIT000083522"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q24-25"
gene 1..1464
/gene="OPRM"
CDS 50..1390
/gene="OPRM"
/note="alternatively spliced; exon 4 of the MOR-1 gene is
replaced by a new exon"
/codon_start=1
/product="mu opioid receptor variant MOR-1R"
/protein_id="AAK74189.1"
/translation="MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDP
CGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMK
TATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTL
CTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSID
CTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRN
LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLN
PVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQCLPI
PSLSCWALEHGCLVVYPGPLQGPLVRYDLPAILHSSCLRGNTAPSPSGGAFLLS"
BASE COUNT 334 a 440 c 303 g 387 t
ORIGIN
1 cggtgctcct ggctacctcg cacagcgtgc ccgcccggcc gtcagtacca tggacagcag
61 cgctgccccc acgaacgcca gcaattgcac tgatgccttg gcgtactcaa gttgctcccc
121 agcacccagc cccggttcct gggtcaactt gtcccactta gatggcaacc tgtccgaccc
181 atgcggtccg aaccgcaccg acctgggcgg gagagacagc ctgtgccctc cgaccggcag
241 tccctccatg atcacggcca tcacgatcat ggccctctac tccatcgtgt gcgtggtggg
301 gctcttcgga aacttcctgg tcatgtatgt gattgtcaga tacaccaaga tgaagactgc
361 caccaacatc tacattttca accttgctct ggcagatgcc ttagccacca gtaccctgcc
421 cttccagagt gtgaattacc taatgggaac atggccattt ggaaccatcc tttgcaagat
481 agtgatctcc atagattact ataacatgtt caccagcata ttcaccctct gcaccatgag
541 tgttgatcga tacattgcag tctgccaccc tgtcaaggcc ttagatttcc gtactccccg
601 aaatgccaaa attatcaatg tctgcaactg gatcctctct tcagccattg gtcttcctgt
661 aatgttcatg gctacaacaa aatacaggca aggttccata gattgtacac taacattctc
721 tcatccaacc tggtactggg aaaacctgct gaagatctgt gttttcatct tcgccttcat
781 tatgccagtg ctcatcatta ccgtgtgcta tggactgatg atcttgcgcc tcaagagtgt
841 ccgcatgctc tctggctcca aagaaaagga caggaatctt cgaaggatca ccaggatggt
901 gctggtggtg gtggctgtgt tcatcgtctg ctggactccc attcacattt acgtcatcat
961 taaagccttg gttacaatcc cagaaactac gttccagact gtttcttggc acttctgcat
1021 tgctctaggt tacacaaaca gctgcctcaa cccagtcctt tatgcatttc tggatgaaaa
1081 cttcaaacga tgcttcagag agttctgtat cccaacctct tccaacattg agcaacaaaa
1141 ctccactcga attcgtcaga acactagaga ccacccctcc acggccaata cagtggatag
1201 aactaatcat cagtgcctac ctataccttc cctgtcttgc tgggctctag agcatggctg
1261 cttggttgtg taccctggac cactgcaagg acctcttgtc agatatgacc tcccagctat
1321 ccttcactcg tcctgccttc gtggaaatac tgctcccagc ccgtctggtg gggcatttct
1381 cttgagttaa gcatgattat tcttcagttg cccgacactg cccttgactc ccttccaaat
1441 tcggcatttt cacatcagta tggc
//