LOCUS AY033495 1982 bp mRNA linear HUM 28-APR-2004
DEFINITION Homo sapiens keratin protein K6irs (KRT6) mRNA, complete cds.
ACCESSION AY033495
VERSION AY033495.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1982)
AUTHORS Porter,R.M., Corden,L.D., Lunny,D.P., Smith,F.J., Lane,E.B. and
McLean,W.H.
TITLE Keratin K6irs is specific to the inner root sheath of hair
follicles in mice and humans
JOURNAL Br. J. Dermatol. 145 (4), 558-568 (2001)
PUBMED 11703281
REFERENCE 2 (bases 1 to 1982)
AUTHORS McLean,W.H.I.
TITLE Direct Submission
JOURNAL Submitted (26-APR-2001) Human Genetics Unit, University of Dundee,
Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
FEATURES Location/Qualifiers
source 1..1982
/db_xref="H-InvDB:HIT000083441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1982
/gene="KRT6"
5'UTR 1..56
/gene="KRT6"
primer_bind 1..20
/note="HK6irs.p1"
primer_bind 10..29
/note="HK6irs.p3"
CDS 57..1589
/gene="KRT6"
/note="type II intermediate filament protein; expressed in
the inner root sheath of hair follicles"
/codon_start=1
/product="keratin protein K6irs"
/protein_id="AAK55108.1"
/translation="MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASF
GSKSLSCLGGSRSLALSAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTV
NKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL
QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVE
INRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS
DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD
DLKLTKAEISELNRLIQRIRSEIGNVKKCADLETAIADAEQRGDCALKDARAKLDELE
GALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI
SSTNAGAGGAGFSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKA
SR"
primer_bind 797..816
/note="HK6irs.p5"
primer_bind complement(977..996)
/note="HK6irs.p6"
primer_bind 1212..1233
/note="HK6irs.p7"
3'UTR 1590..1982
/gene="KRT6"
primer_bind complement(1702..1721)
/note="HK6irs.p4"
primer_bind complement(1959..1982)
/note="HK6irs.p2"
regulatory 1965..1970
/regulatory_class="polyA_signal_sequence"
/gene="KRT6"
BASE COUNT 429 a 577 c 588 g 388 t
ORIGIN
1 gcggctgttt gcgccccttc tgcctcccgc gcggccagca ccggtacttg cgagccatga
61 gccgccaact gacccatttc ccccgcgggg agcgcctggg cttcagcggt tgctccgcgg
121 tcctctctgg cgggatcggc agcagctccg cctcattccg ggcccgggtc aagggctcgg
181 cctcctttgg cagcaagagc ctctcctgcc ttgggggcag ccgaagcctg gcgctcagcg
241 ctgctgcacg gcggggcggc ggccgcctgg gcggcttcgt gggcaccgcc ttcggcagcg
301 ccgggctggg gcccaagtgt ccctccgtgt gcccacccgg gggcatccct caggtcaccg
361 tcaacaagag cctcctggcc ccgctcaacg tggagatgga ccccgagatc cagagggtgc
421 gcgcccagga gcgggagcag atcaaggcgc taaacaacaa gttcgcctcc ttcatcgaca
481 aggtgcggtt cctggagcag cagaatcagg tgctagagac caagtggaac ctcctacagc
541 agctggactt gaacaactgc aggaagaacc tggagcccat ttatgagggc tacatcagca
601 acctgcagaa gcagctggag atgctgtctg gggacggggt gaggctggat tcggagctga
661 ggaacatgca ggatttggtg gaggactaca agaagaggta tgaggtggag attaacagac
721 gcacagctgc tgagaatgag tttgtggtgc tcaagaagga cgtggatgct gcttacatga
781 ataaggttga gctccaggcc aaggtggact ccttgacaga tgagattaaa ttcttcaagt
841 gcctttatga aggggagatc actcagatcc agtcccacat cagcgacacg tccatcgtcc
901 tgtcaatgga caacaaccgg gatctggacc tggacagcat cattgccgag gtccgtgccc
961 agtacgagga gattgcccta aagagcaagg ccgaggctga gaccctgtac cagaccaaga
1021 tccaggagct gcaggtcaca gcaggccagc atggggatga cctcaagctc accaaggctg
1081 aaatctctga gctcaaccgc ctgatccaga ggatccgctc agagataggg aatgtgaaga
1141 agtgtgccga tctggagacg gccatcgccg acgctgaaca gcggggggac tgcgccctga
1201 aagatgcccg ggccaagctg gatgagctgg agggcgccct gcaccaggcc aaggaggagc
1261 tggcacggat gctgcgtgag taccaggagc tcgtgagcct gaagctggcc ctggatatgg
1321 agatcgccac ctaccgcaag ctgctggaga gcgaggagtg caggatgtct ggcgaatatc
1381 caaattctgt gagcatctcc gtcatcagca gcaccaatgc tggggcagga ggggctggct
1441 tcagcatggg ctttggcgcc tcaagcagtt atagctacaa aactgcagct gcagacgtca
1501 agaccaaagg cagctgtggc agtgagctca aggatcccct tgccaaaacc tcggggagca
1561 gctgtgccac caaaaaggcc tccagatgat ggacaagtgg ttggctctgt gagcagaagg
1621 cttcccaact cacccgtctc ctccctctcc ttccctgggc tccctttcca agtcaagaaa
1681 tgctttgtct gtcactacag tcccaacccc atttcctctc cctgttgtcc tcaaggtgtg
1741 atgcttcgat gcaaggagtc cagtcaggag ctctctcagt ggcctccttc ttggtcccgt
1801 ttcgttgggt cattgcctga aatgcaaaga caacacttac ccaggatgtt tccccaaggc
1861 cagctacaag cccctctgcc cccatgcctt tcttgggcct tcactaccaa gggactctct
1921 tcatcttctg attgggattg tgtccagtcc tctgcttctt ctgcaataaa tgattaaatc
1981 tg
//