LOCUS AY033486 7005 bp mRNA linear HUM 22-MAY-2001
DEFINITION Homo sapiens ATP-binding cassette transporter family A member 12
(ABCA12) mRNA, complete cds.
ACCESSION AY033486
VERSION AY033486.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7005)
AUTHORS Bonner,T.I., Moses,T. and Detera-Wadleigh,S.
TITLE A retinal cDNA for the ATP-binding cassette transporter ABCA12
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7005)
AUTHORS Bonner,T.I., Moses,T. and Detera-Wadleigh,S.
TITLE Direct Submission
JOURNAL Submitted (26-APR-2001) Laboratory of Genetics, National Institute
of Mental Health, Bldg. 36, Room 3D06, MSC 4094, Bethesda, MD
20892, USA
FEATURES Location/Qualifiers
source 1..7005
/db_xref="H-InvDB:HIT000083440"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/tissue_type="retina"
gene 1..7005
/gene="ABCA12"
CDS 160..6993
/gene="ABCA12"
/note="similar to the sequence contained in GenBank
Accession Number AL080207"
/codon_start=1
/product="ATP-binding cassette transporter family A member
12"
/protein_id="AAK54355.1"
/translation="MFTYIKIITSGDSDNITHVWNEDDGQTLSPSSLAAQLLILENFE
DALLNISANSPYIPYLACVRNVTDSLARGSPENLRLLQSTIRFKKSFLRNGSYEDYFP
PVPEVLKSKLSQLRNLTELLCESETFSLIEKSCQLSDMSFGSLCEESEFDLQLLEAAE
LGTEIAASLLYHDNVISKKVRDLLTGDPSKINLNMDQFLEQALQMNYLENITQLIPII
EAMLHVNNSADASEKPGQLLEMFKNVEELKEDLRRTTGMSNRTIDKLLAIPIPDNRAE
IISQVFWLHSCDTNITTPKLEDAMKEFCNLSLSERSRQSYLIGLTLLHYLNIYNFTYK
VFFPRKDQKPVEKMMELFIRLKEILNQMASGTHPLLDKMRSLKQMHLPRSVPLTQAMY
RSNRMNTPQGSFSTISQALCSQGITTEYLTAMLPSSQRPKGNHTKDFLTYKLTKEQIA
SKYGIPINTTPFCFSLYKDIINMPAGPVIWAFLKPMLLGRILYAPYNPVTKAIMEKSD
VTLRQLAELREKSQEWMDKSPLFMNSFHLLNQAIPMLQNTLRNPFVQVFVKFSVGLDA
VELLKQIDELDILRLKLENNIDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMERE
AKRLYKSNELFGSVIFKLPSNRSWHRGYDSGNVFLPPVIKYTIRMSLKTAQTTRSLRT
KIWAPGPHNSPSHNQIYGRAFIYLQDSIERAIIELQTGRNSQEIAVQVQAIPYPCFMK
DNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLI
ESVGFLLVTIVILIIILKFGNILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNI
AALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFSYASQYIARYEEQGIG
LQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPIL
PSYWKERFGCAEVKPEKSNGLMFTNIMMQNTNPSASPEYMFSSNIEPEPKDLTVGVAL
HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYG
KDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLK
DTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS
KNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKK
SPNLNANAVCDTMAVTAMIQSHLPEAYLKEDIGGELVYVLPPFSTKVSGAYLSLLRAL
DNGMGDLNIGCYGISDTTVEEVFLNLTKESQKNSAMSLEHLTQKKIGNSNANGISTPD
DLSVSSSNFTDRDDKILTRGERLDGFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILP
IVFVTTAMGLGTLRNSSNSYPEIQISPSLYGTSEQTAFYANYHPSTEALVSAMWDFPG
IDNMCLNTSDLQCLNKDSLEKWNTSGEPITNFGVCSCSENVQECPKFNYSPPHRRTYS
SQVIYNLTGQRVENYLISTANEFVQKRYGGWSFGLPLTKDLRFDITGVPANRTLAKVW
YDPEGYHSLPAYLNSLNNFLLRVNMSKYDAARHGIIMYSHPYPGVQDQEQATISSLID
ILVALSILMGYSVTTASFVTYVVREHQTKAKQLQHISGXGVTCYWVTNFIYDMVFYLV
PVAFSIGIIAIFKLPAFYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITY
VCVNLFFGINSIVSLSVVYFLSKEKPNDPTLELISETLKRIFLIFPQFCFGYGLIELS
QQQSVLDFLKAYGVEYPNETFEMNKLGAMFVALVSQGTMFFSLRLLINESLIKKLRLF
FRKFNSSHVRETIDEDEDVRAERLRVESGAAEFDLVQLYCLTKTYQLIHKKIIAVNNI
SIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVG
YCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSY
GTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSME
ECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTKFMQLHF
PKTYLKDQHLSMLEYHVPVTAGGVANIFDLLETNKTALNITNFLVSQTTLEEVFINFA
KDQKSYETADTSSQGSTISVDSQDDQMES"
BASE COUNT 2084 a 1549 c 1424 g 1946 t
ORIGIN
1 atttcctata aatatcacaa atatttccaa caaaagagca tagatgtctt ttatacaatt
61 cttttgagaa tgattctgca gatttctgca ttttctcctc attaatttga cctgggatgg
121 ttttcactga ggaaaaaaat ctttaagcaa acatgttaaa tgtttaccta tataaaaatt
181 attacttcag gtgactccga taatataacg catgtgtgga atgaggatga tggacagacc
241 ttatctccaa gcagtctggc tgcacagctc ctaattctgg aaaactttga agatgccctc
301 ttaaatatat cagcaaatag tccttatatt ccttacttgg catgtgtgag aaatgtgact
361 gacagtttgg ccagaggttc accagaaaat ctaagactcc tgcagtccac aatacgattt
421 aaaaaatctt ttcttcgcaa tggttcctat gaagattact ttcctccagt tcctgaagtc
481 ctaaaatcaa aactgtctca acttcgaaac ttgaccgaac ttctttgtga atctgaaact
541 ttcagtttga tagagaagtc atgccagctc tctgatatga gctttgggag cctgtgtgaa
601 gaaagtgagt ttgatctgca actcctcgaa gcggcagagc tgggcaccga aatagcagcc
661 agcttactgt accatgacaa tgtcatatct aaaaaagtga gagatttgct gactggagat
721 ccaagcaaaa ttaatttaaa tatggatcag tttctagaac aggcactgca aatgaattac
781 ttggaaaata tcactcagtt aataccgatc atagaagcca tgctgcatgt caataacagt
841 gcagatgctt ctgaaaagcc aggtcagtta ctagaaatgt ttaaaaatgt tgaagagctg
901 aaagaagatt taaggagaac aacaggaatg tccaacagga ctattgacaa gttgctggcc
961 attcccatcc ctgataatag agctgagatt atttctcagg tgttctggct gcattcctgt
1021 gatactaata tcaccactcc caaactagaa gatgcaatga aagaattctg caacctgtct
1081 ctttcagaga gatcccggca gtcttacctc atcggactca cccttctgca ctacttaaac
1141 atttacaact tcacatacaa ggtgtttttc ccgaggaaag atcaaaagcc agtagaaaag
1201 atgatggagc tcttcataag actaaaagag attctcaatc agatggcttc tggcacacat
1261 ccgctgctag acaaaatgag atccctgaag caaatgcatc tgcccagaag tgttccatta
1321 acacaggcaa tgtacagaag caaccgaatg aacacaccac aaggatcatt tagcaccatc
1381 tcccaagcat tatgttctca aggaattacc actgaatatt taactgccat gctgccctct
1441 tcccagaggc caaaaggcaa ccacaccaag gattttttga cttataaatt aactaaagag
1501 caaattgctt caaaatatgg aattcccata aataccacac cattttgctt ctccctttat
1561 aaagacatca ttaacatgcc cgctggacct gtgatttggg ctttcttgaa acctatgttg
1621 ttgggaagaa ttttgtatgc accatataac ccagtcacaa aggcaataat ggaaaagtcc
1681 gatgtaactc tgagacagct ggcggaatta agagaaaaat ctcaagagtg gatggataag
1741 tcgccacttt tcatgaattc cttccatctg ttaaaccagg caattccaat gctccagaat
1801 actctaagga acccttttgt gcaagttttt gtaaagttct ccgtgggact cgatgctgtt
1861 gaactattga aacagataga tgaactcgat attctaagac tgaaattaga gaacaacatt
1921 gacatcatcg atcagcttaa cacactatct tccctgacag taaatatttc ctcttgtgta
1981 ttatatgacc gtattcaggc agcaaaaacc atagatgaaa tggagagaga ggctaaaagg
2041 ctctacaaaa gcaacgaact ctttggaagt gttattttta agcttccttc taacagaagc
2101 tggcacagag gctatgactc tggaaatgtc tttcttcctc ctgtcataaa atataccatc
2161 cggatgagtc tcaagaccgc acagaccaca agaagcctaa gaaccaagat ttgggctcca
2221 gggccacaca attctccatc acacaaccag atctatggca gggcttttat ttatttacag
2281 gatagtattg aaagagcaat cattgaattg caaactggaa ggaactccca ggaaatagca
2341 gtccaggttc aagcaattcc ttatccctgc ttcatgaaag acaacttcct aaccagtgtc
2401 tcttattctc ttccaattgt gcttatggtt gcctgggttg tatttatagc tgcctttgta
2461 aaaaagcttg tctatgagaa agacctccgg cttcatgagt acatgaagat gatgggtgtg
2521 aactcctgca gccatttctt tgcctggctt atagagagtg ttggattttt actggttacc
2581 atcgtgatcc tcatcattat actcaagttt ggcaatattc ttcctaaaac aaatgggttc
2641 attttgttcc tgtatttttc ggactacagc ttctcggtta ttgccatgag ctatcttatc
2701 agtgtcttct tcaacaacac caacattgca gctctgatcg gaagcctcat ctacatcatt
2761 gccttctttc catttattgt tctggttaca gtggagaatg agttgagcta tgtattgaaa
2821 gtgttcatga gcctgctgtc cccaacagca ttcagctatg caagccaata cattgcacga
2881 tacgaagaac agggcattgg tcttcagtgg gaaaatatgt acacctcccc ggttcaggat
2941 gacaccacct catttggctg gctgtgctgt ctaatcctag ctgactcttt catttatttc
3001 cttattgctt ggtatgtcag gaatgtcttc ccagggacat acggtatggc agctccctgg
3061 tattttccaa ttcttccttc ctattggaag gagcgatttg ggtgtgcaga ggtgaagcct
3121 gagaagagca atggcctcat gtttactaac atcatgatgc agaacaccaa cccatctgcc
3181 agtcctgaat acatgttttc ctctaacatc gagcctgaac ctaaagatct cacagtcggg
3241 gttgccctgc atggggtcac aaagatctat ggctcaaaag ttgctgttga taacctcaat
3301 ctgaactttt atgaagggca tattacttca ttgctggggc ccaatggagc tgggaaaact
3361 actaccattt ccatgttaac tgggctgttt ggggcctcag caggcaccat ttttgtatat
3421 ggaaaagata tcaaaacaga cctacacacg gtacggaaga acatgggagt ctgtatgcag
3481 cacgacgtct tgttcagtta cctcactact aaggagcacc ttctcctata tggttccatc
3541 aaagttcctc actggactaa aaagcagctc cacgaggaag taaaaaggac tttaaaagat
3601 actggactat atagccatcg tcataagaga gttggaacac tgtcaggagg catgaagagg
3661 aagttatcta tatccatagc tctcattggt ggatcaaggg tagtaatttt ggatgaacca
3721 tctactggag ttgacccatg ttctcgccga agtatatggg atgttatatc caagaacaaa
3781 actgccagaa caatcattct gtcaacgcac cacttggacg aggctgaagt gctgagtgac
3841 cgcatcgcct tcctggagca gggtgggctt aggtgctgtg ggtccccatt ttacctcaag
3901 gaagcctttg gcgatgggta tcacctcacg cttaccaaga agaagagtcc aaatttaaat
3961 gcaaatgcag tatgtgacac catggccgtg acagcaatga tccaatcaca tctccccgaa
4021 gcctacctca aggaggatat tgggggagag cttgtttatg tacttcctcc attcagcacc
4081 aaagtctcag gggcctacct gtcactccta cgggcactcg acaatggcat gggtgacctc
4141 aacatcgggt gctacggcat ttcagatacc accgtggagg aggtctttct gaacttgacc
4201 aaagagtcac aaaaaaatag tgctatgagt cttgagcact taacacaaaa gaaaattggg
4261 aattccaatg ccaatggcat ctcaactcct gacgatttat ctgtgagcag cagcaatttc
4321 acagacagag atgacaaaat cctgacaaga ggagagaggc tggatggctt tggactgttg
4381 ctgaagaaga tcatggctat actcatcaag aggttccacc acacccgcag gaactggaaa
4441 ggtctcattg ctcaggttat cctccccatc gtctttgtta ccactgccat gggccttggc
4501 acactgagaa attccagcaa cagttatcca gagattcaga tctccccctc tctttatggt
4561 acctccgaac agacagcctt ctatgctaat tatcacccga gcacggaagc acttgtctca
4621 gcaatgtggg acttccctgg aattgacaac atgtgtctga acaccagtga tctacagtgt
4681 ttaaacaaag acagtctgga aaaatggaac accagtggag aacccatcac taattttggt
4741 gtttgctcct gctcagaaaa tgtccaggaa tgtcctaaat ttaactattc cccaccgcac
4801 agaagaactt actcatccca ggtaatttat aacctcactg ggcaacgagt ggaaaattat
4861 cttatatcaa ctgcaaatga gtttgtccaa aaaagatatg gaggttggag ttttgggctg
4921 cctttgacaa aagaccttcg ttttgatata acaggagtcc ctgccaatag aacacttgcc
4981 aaggtatggt atgatccaga aggctatcac tcccttccag cttacctcaa cagcctgaat
5041 aatttccttc tgcgagttaa catgtcaaaa tacgatgctg cccgacatgg catcatcatg
5101 tatagccatc cttatccagg agtgcaagac caagaacaag ccacaatcag cagtttaatc
5161 gatattttag tggcactgtc tatcttgatg ggctactctg tcacyaccgc cagctttgtc
5221 acctatgttg taagggaaca tcaaaccaaa gccaaacagt tgcagcacat ttcaggcayt
5281 ggcgtgacat gctactgggt aacaaacttc atttatgaca tggttttcta cttggtgcct
5341 gtagcgtttt caattggtat cattgcgatt ttcaaattac ctgcattcta cagtgaaaac
5401 aacctaggcg ctgtatctct cctacttctc ctgtttgggt atgcaacatt ttcttggatg
5461 tacttgctgg ctgggctctt ccatgaaaca ggaatggcct tcatcactta cgtctgtgtc
5521 aacttgtttt ttggcattaa ttccattgtt tccctgtcag tggtatactt tctttccaag
5581 gaaaagccta atgatccgac tttagaactt atttctgaaa ccctcaagcg cattttcctg
5641 attttcccac aattctgttt tggctacggt ttgattgaac tttctcaaca acagtcggtc
5701 ctagacttct taaaagcata tggagtggaa tacccaaatg aaacctttga gatgaataaa
5761 ctaggtgcaa tgtttgtggc tttggtttct cagggcacca tgtttttttc cttgcgactc
5821 ttaatcaacg aatccctgat aaagaaactc aggcttttct tcagaaaatt taattcttca
5881 catgtaaggg agacaataga tgaggatgaa gatgtgcggg ctgagagatt aagagttgag
5941 agtggtgcag ctgaatttga cttggtccaa ctttattgtc tcacaaagac ctaccaactt
6001 atccacaaaa agattatagc tgtaaacaac atcagcattg ggatacctgc tggagagtgt
6061 tttgggcttc ttggagtgaa tggagcagga aagaccacta tattcaagat gctgacagga
6121 gacatcattc cttcaagtgg aaacattctg atcagaaata agaccggatc tctgggtcac
6181 gttgattctc acagctcatt agttggctac tgtcctcagg aagatgcctt agatgacctg
6241 gtaactgtgg aagaacattt gtatttctat gccagggtac atggaattcc agaaaaggat
6301 attaaagaaa ctgttcataa actccttagg agacttcacc tgatgccctt caaggacaga
6361 gctacctcta tgtgcagtta tggcacaaaa agaaaattat ccactgcact ggccttgata
6421 gggaaacctt ccattctact gctggatgag ccgagctctg gcatggatcc gaagtcgaaa
6481 cggcacctct ggaagatcat ttcagaagaa gtacagaaca aatgttccgt catcctcaca
6541 tctcacagca tggaagaatg tgaagctctc tgtaccaggt tggccattat ggtgaatgga
6601 aagtttcaat gtattggatc tttgcagcac ataaagagca ggtttggacg aggatttact
6661 gtcaaagttc acttgaagaa taacaaagtg accatggaga ccctcacaaa gttcatgcag
6721 ctgcactttc caaaaacata cttaaaagat cagcacctca gcatgctaga gtatcatgta
6781 ccagtcacag caggaggagt cgcaaacatt tttgatctgc tggaaaccaa caagactgct
6841 ttaaatatta caaatttctt agtgagtcag accactctgg aagaggtttt catcaacttt
6901 gccaaagacc agaagtccta tgaaactgct gataccagca gccaaggttc cactataagt
6961 gttgactcac aagatgacca gatggagtct taacacttcc agcaa
//