LOCUS AY032928 3908 bp mRNA linear HUM 07-DEC-2001
DEFINITION Homo sapiens CARD-containing MAGUK 3 protein (CARMA3) mRNA,
complete cds.
ACCESSION AY032928
VERSION AY032928.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3908)
AUTHORS Gaide,O., Martinon,F., Micheau,O., Bonnet,D., Thome,M. and
Tschopp,J.
TITLE Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10
phosphorylation and NF-kappaB activation
JOURNAL FEBS Lett. 496 (2-3), 121-127 (2001)
PUBMED 11356195
REFERENCE 2 (bases 1 to 3908)
AUTHORS Martinon,F., Thome,M. and Tschopp,J.
TITLE Direct Submission
JOURNAL Submitted (23-APR-2001) Institute of Biochemistry, University of
Lausanne, Ch. des Boveresses 155, Epalinges, VD 1066, Switzerland
FEATURES Location/Qualifiers
source 1..3908
/db_xref="H-InvDB:HIT000083380"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3908
/gene="CARMA3"
CDS 4..3102
/gene="CARMA3"
/note="contains caspase recruitment domain CARD, coiled
coil, PDZ, SH3, guanylate kinase domain GUK; interacts
with the CARD-containing molecule Bcl10 (CARMEN)"
/codon_start=1
/product="CARD-containing MAGUK 3 protein"
/protein_id="AAK54454.1"
/translation="MPGRAEAGEAEEEAGAGSGSEAEEDALWERIEGVRHRLARALNP
AKLTPYLRQCRVIDEQDEEEVLSTYRFPCRVNRTGRLMDILRCRGKRGYEAFLEALEF
YYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQAR
GRVLEEERAGLEQRLRDQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSE
EKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPPPGAEEKEKEKEKEKEPDN
VDLVSELRAENQQLTASLRELQEGLQQEASRPGAPGSERILLDILEHDWREAQDSRQE
LCQKLHAVQGELQWAEELRDQYLQEMEDLRLKHRTLQKDCDLYKHRMATVLAQLEEIE
KERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTLTSLEGTKALLEVQ
LQRAQGGTCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAAVMGGPEPHNSEE
ATDSEKEINRLSILPFPPSAGSILRRQREEDPAPPKRSFSSMSDITGSVTLKPWSPGL
SSSSSSDSVWPLGKPEGLLARGCGLDFLNRSLAIRVSGRSPPGGPEPQDKGPDGLSFY
GDRWSGAVVRRVLSGPGSARMEPREQRVEAAGLEGACLEAEAQQRTLLWNQGSTLPSL
MDSKACQSFHEALEAWAKGPGAEPFYIRANLTLPERADPHALCVKAQEILRLVDSAYK
RRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLPSSRHRGPRSNLKKRALD
QLRLVRPKPVGAPAGDSPDQLLLEPCAEPERSLRPYSLVRPLLVSALRPVVLLPECLA
PRLIRNLLDLPSSRLDFQVCPAESLSGEELCPSSAPGAPKAQPATPGLGSRIRAIQES
VGKKHCLLELGARGVRERVQNEIYPIVIHVEVTEKNVREVRGLLGRPGWRDSELLRQC
RGSEQVLWGLPCSWVQVPAHEWGHAEELAKVVRGRILQEQARLVWVECGSSRGCPSSS
EA"
BASE COUNT 715 a 1205 c 1309 g 679 t
ORIGIN
1 gccatgccgg gccgggcgga ggcgggggag gccgaggagg aggccggggc cggctcgggg
61 tctgaggcgg aggaggacgc gctgtgggag cgaatcgagg gcgtccggca tcggctggct
121 cgcgccctga acccggccaa gctcacgccg tatctgcgcc agtgccgggt catcgacgag
181 caggacgagg aggaggtgct gagcacctac cgcttcccgt gccgcgtcaa ccgcaccggg
241 cgcctgatgg acatcttgcg ctgccgtggc aagaggggct atgaggcctt cctggaagcc
301 ctggagttct actaccccga acacttcacg ctgctcacgg gccaggaacc cgcccagcgc
361 tgctccatga tcctcgatga ggaggggcct gagggcctga cccaattctt gatgacagag
421 gtgcgacggc tgcgggaagc tcgcaagagc cagctgcagc gggagcagca actgcaggcc
481 cggggccggg tgctcgagga ggagcgggca gggctggagc agcggctgcg ggaccagcag
541 caggctcagg agcgctgtca acggctgcgg gaggactggg aggcgggcag cctggagctg
601 ctgcggctca aggatgagaa ctacatgatc gccatgcgcc tggcacagct cagtgaggag
661 aagaactcgg ctgtacttcg cagccgtgac ctgcagctgg cggtggatca gctcaagctc
721 aaagtgagtc ggctggagga agagtgtgca ctgcttcgaa gggccagggg cccgccccct
781 ggggcagagg agaaggagaa ggagaaggag aaggagaagg agccagacaa tgtggacctt
841 gtctctgagc tgcgtgctga gaaccagcag ctgacggcgt cactgcggga gttgcaggag
901 ggcctgcagc aggaggcgag ccggccgggg gccccgggct ccgagcgcat cctgctggac
961 atcctagagc atgactggcg ggaggcgcag gacagcaggc aggagctgtg ccagaagctg
1021 catgccgtgc agggggagct gcagtgggcc gaggagctgc gcgaccagta cctgcaggag
1081 atggaagacc tgcggctcaa gcaccgcacg ctgcagaagg actgtgacct gtacaagcac
1141 cgcatggcca ctgtcctggc ccaactggag gagattgaga aggagcgaga ccaggccatc
1201 cagagccgtg accggatcca gttgcagtac tcacagagcc tcatcgagaa ggaccagtac
1261 cgcaagcagg tgcggggcct ggaggcggag cgggatgagc tgctgacaac gctcaccagc
1321 ctggagggca ccaaggctct gctggaggtt cagctgcagc gggcccaggg tggcacctgc
1381 ctcaaggcct gtgcctcctc ccattccctg tgctccaacc tcagcagcac ttggagcctg
1441 agcgagttcc cctcccctct gggaggccca gaagcaactg gggaggcagc tgtcatgggg
1501 ggacctgagc ctcacaactc ggaggaagcc acagacagtg aaaaggagat caatcggctc
1561 tccatcctgc ccttcccccc cagtgccggc tccatcctcc gccggcagcg tgaggaagac
1621 cccgcacccc ctaagagatc cttcagcagc atgtcagaca tcacagggag tgtgacactt
1681 aagccctggt cccctggcct ctcttcgtcc tcatcctctg acagcgtgtg gcctttggga
1741 aagccggaag gcctcctggc tcggggctgt ggcctggact tcctcaacag gtctctggct
1801 attcgggtgt ctggccggag ccccccaggg ggcccagagc cgcaggacaa gggaccagat
1861 ggactgtcgt tttatgggga cagatggtct ggggctgtgg tgcgcagggt gctgtctggg
1921 cctgggtccg ccaggatgga accaagagag caaagggtgg aagctgctgg tctggagggg
1981 gcgtgcctgg aagccgaggc ccagcagaga accttgctct ggaatcaggg gtccacactc
2041 ccctccctga tggactcgaa ggcctgccag tccttccacg aggccctaga agcctgggca
2101 aagggaccag gtgccgagcc cttctacatt cgtgccaacc tcaccttgcc tgagagggca
2161 gatccccatg ccctttgcgt gaaagcccaa gagatccttc gactggtgga ctcggcatac
2221 aagcggaggc aggaatggtt ctgcacccgg gttgaccccc tcactctgcg ggacctggac
2281 cggggcaccg tgcccaatta tcagagagcc cagcagctcc tagaagttca ggagaaatgc
2341 ctgccctcca gccggcaccg aggcccccgc agtaatctga agaagagagc cctggaccag
2401 ctgcggctgg tgaggcccaa gcccgtgggg gcgcctgcag gggactcccc ggatcagctg
2461 ctgctggagc cctgtgcaga gccggagcgg agcctcagac cctacagttt ggtgcggccg
2521 ctactggtgt ctgccctgcg gcccgtggtg ctgttgcctg agtgcctggc gccccggctc
2581 atccgtaacc tgctagacct gcccagctcc cggctggact tccaagtgtg cccagcggaa
2641 agcctctctg gggaggaact gtgcccatcc tcagcgcctg gagcccccaa ggctcagcct
2701 gccacccctg ggctaggcag caggatccgg gccatccagg agtctgttgg gaagaagcac
2761 tgcctgctgg agctgggtgc tcggggtgtg cgggagcggg tgcagaacga gatctacccc
2821 atcgtcatcc acgtggaggt gactgagaag aatgtccggg aagtcagggg tctgctgggc
2881 cggccgggct ggcgggactc agagctgctg cggcagtgcc gtggctcaga gcaggtgctc
2941 tgggggctgc cctgctcctg ggtgcaggtg cccgcccatg agtggggaca cgcagaggag
3001 ctggccaagg tggtgcgcgg ccgcatcctg caggagcagg cccgcctcgt gtgggtggag
3061 tgcggcagca gcagaggctg ccccagcagc agtgaggcct gaggctcatc tgatacctgc
3121 accttctccc caagccagcg tggaccctgg tgtctatggt gaagctgggc cctcccaccc
3181 tgagccttcc tagacccttg gactctcaga tgcagggccc ttggctctgg cctctcaccc
3241 ccaaggctgt ctctggccct gccgagccta tgggagtccc gggacagagt gcccactccc
3301 ctctacttgc tgctctgggc ctccccacct ttcctggggt ctccacattc ccactagtgg
3361 gtcttatgtg tgtctgtgtc ttctccttaa acactcgccc tggagtctgt tctcacacct
3421 gtgcgcaggt ttgcacactc aagttctcat gggcaggctc aggtctgtcc cgctgccctg
3481 ggcacgaggt ctcctgagga cctgggcctg ttctgctcct aggagacctg agcccgttac
3541 cgcgtgactc ccaccatcca gctcgcgctc ctcgtggatt cagccatgca tggactgggg
3601 tgttccctgg cccatggtca cctgtgcccc tcgtgtctcc tcacatgggt gtctgtggtt
3661 ctctcctgtg taaatgtcac gccccacccc tgtttcatgt gggcactaac acgtgtgcgt
3721 tcctggcggg cacacacagg accgtgcctc acagggccca ctccctgcct atgcctccct
3781 cttggggggc cgaggagggc ggctgctctg tcatgagaat gtacggcccg tggatgatta
3841 acgggccttt ttcacttaga agctgcacat tatggagcat taaacacttt tgtcataaaa
3901 aaaaaaaa
//