LOCUS AY029237 6845 bp mRNA linear HUM 08-AUG-2003
DEFINITION Homo sapiens protocadherin 15 mRNA, complete cds.
ACCESSION AY029237
VERSION AY029237.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6845)
AUTHORS Ahmed,Z.M., Riazuddin,S., Bernstein,S.L., Ahmed,Z., Khan,S.,
Griffith,A.J., Morell,R.J., Friedman,T.B., Riazuddin,S. and
Wilcox,E.R.
TITLE Mutations of the protocadherin gene PCDH15 cause Usher syndrome
type 1F
JOURNAL Am. J. Hum. Genet. 69 (1), 25-34 (2001)
PUBMED 11398101
REFERENCE 2 (bases 1 to 6845)
AUTHORS Ahmed,Z., Riazuddin,S., Bernstein,S.L., Morell,R.J., Griffith,A.J.,
Friedman,T.B. and Wilcox,E.R.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2001) Laboratory of Molecular Genetics, National
Institute on Deafness and Other Communication Disorders, 5 Research
Court, 2A-19, Rockville, MD 20850-3227, USA
FEATURES Location/Qualifiers
source 1..6845
/db_xref="H-InvDB:HIT000083329"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q21.1"
CDS 396..6263
/note="PCDH15"
/codon_start=1
/product="protocadherin 15"
/protein_id="AAK31804.1"
/translation="MFRQFYLWTCLASGIILGSLFEICLGQYDDDCKLARGGPPATIV
AIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLMDPVKQMLFLNSTGRV
LDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELT
PVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVLRK
RLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD
CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDY
PRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQS
PYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTS
VFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPT
FPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT
IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLE
ISEAMRVGAVLLNLQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTD
RYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVK
ATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHP
RHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRI
RSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTV
IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQF
PYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPG
EIPRFTQEEYRPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGV
IYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK
KFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLI
KTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEK
KIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAFSLEDYTKCDLTVYAIDPQTNRA
IDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALL
ALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQAALPAAKPAVPAPAPVAAPP
PPPPPPPGAHLYEELGDSSILFLLYHFQQSRGNNSVSEDRKHQQVVMPFSSNTIEAHK
SAHVDGSLKSNKLKSARKFTFLSDEDDLSAHNPLYKENISQVSTNSDISQRTDFVDPF
SPKIQAKSKSLRGPREKIQRLWSQSVSLPRRLMRKVPNRPEIIDLQQWQGTRQKAENE
NTGICTNKRGSSNPLLTTEEANLTEKEEIRQGETLMIEGTEQLKSLSSDSSFCFPRPH
FSFSTLPTVSRTVELKSEPNVISSPAECSLELSPSRPCVLHSSLSRRETPICMLPIET
ERNIFENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPP
SIPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPSASFLSTECVC
ITGVKCTTNLMPAEKIKSSMTQLSTTTVCKTDPQREPKGILRHVKNLAELEKSVANMY
SQIEKNYLRTNVSELQTMCPSEVTNMEITSEQNKGSLNNIVEGTEKQSHSQSTSL"
BASE COUNT 2067 a 1502 c 1401 g 1875 t
ORIGIN
1 caacgtgctg agctaatagc gacagataga gggcagacag attcctgcta gcagcttagt
61 gttagttgct tgtggtaact aaggcaggtg gcatacatct cagaacgtgg agaatgatgg
121 tatgctttct gagttaacat gttgaactgt tttgcttttc taaaaatttt cctagtaaca
181 ttttcttgat gatatgagag tggatatcaa tgcctcacag aaacaagagg tggaacatgt
241 gaatgaatcg tcttggaact agattatgag cactggttct ttttaaaggg atgtgcaaga
301 ggcagccttg gcaagaaaac ttgctgcata atcttacatg gactaaagat gaaactttaa
361 accgcaaatc agctttgagt gaactttgac agaagatgtt tcgacagttt tatctctgga
421 catgtttagc ttcagggatc atcctgggct ctctctttga aatctgcttg ggccagtatg
481 atgatgattg caaactagct aggggaggac caccagctac catagttgct attgatgaag
541 aaagtcggaa tggtacaatt ctggtggaca acatgctgat caaagggact gctggaggac
601 cagaccccac catagaactt tctttaaagg ataatgtgga ttactgggtg ttgatggatc
661 ctgttaagca aatgcttttc ctgaacagca ccggaagagt tctggataga gatccaccga
721 tgaacataca ctccattgtg gtgcaggtcc agtgcatcaa caaaaaagtg ggcactatta
781 tctaccatga agtgcgaata gtggtgagag acaggaatga caactcaccc actttcaagc
841 atgaaagcta ctatgccaca gtgaatgagc tcactccagt tggtaccaca atattcacag
901 gattttcagg agacaatgga gctacagata tagatgatgg accaaatgga cagatagagt
961 atgttattca gtataatcca gatgatccga catccaatga cacctttgaa attcccctaa
1021 tgttgactgg aaatatagtg ttaaggaaga ggctcaacta tgaagataag actcgctact
1081 ttgtcataat ccaagctaat gaccgtgccc aaaatctgaa tgagaggcga accaccacca
1141 ccactctcac agtggatgtt ctggatggag atgacttggg tccaatgttt cttccttgtg
1201 tccttgtgcc aaacactcgt gattgccgtc cactcactta tcaagctgcc atacctgagt
1261 tgagaactcc ggaagaactg aaccccatta ttgttacgcc accaatccaa gccattgatc
1321 aggaccggaa tattcaaccg ccatcagata ggccaggaat cctctattcc atccttgttg
1381 ggactcctga ggattaccca cgatttttcc atatgcatcc taggacagca gaacttagtc
1441 tcctggagcc agtaaacaga gactttcacc agaaatttga tttggttatt aaggctgaac
1501 aagacaatgg tcatcctctt cctgcctttg ccggtctaca cattgaaata ctggatgaaa
1561 acaatcaaag tccatatttt acaatgccca gttatcaagg ctatatcctg gaatctgccc
1621 cagtgggagc aaccatttcg gacagtctca atttgacttc acctttaaga atagtagctc
1681 tggacaagga catagaagat acaaaagacc cagagcttca cctttttctg aatgactaca
1741 cctcagtctt caccgtcaca cagactggta ttactcgcta cctcacctta cttcaaccag
1801 tggacaggga agaacagcaa acttacacct tttcgataac agcatttgat ggtgtacaag
1861 aaagtgagcc agtcatcgtc aatattcaag tgatggatgc aaatgataac acgccaacct
1921 tccctgaaat atcctatgat gtgtatgttt atacagacat gagacctggg gacagtgtca
1981 tacagctcac tgcagtcgac gcagacgaag ggtcaaatgg ggagatcaca tatgaaatcc
2041 ttgttggggc tcagggagac ttcatcatca ataaaacaac agggcttatc accatcgctc
2101 caggggtgga aatgatagtc gggcggactt acgcactcac ggtccaagca gcggataatg
2161 ctcctcctgc agagcgaagg aactccatct gcactgtgta tattgaagtg cttccaccaa
2221 ataatcaaag ccctcctcgc ttcccacagc tgatgtatag ccttgaaatt agtgaagcca
2281 tgagggttgg tgctgtttta ttaaatctac aggcaactga tcgagaggga gactcaataa
2341 catatgccat tgagaatgga gatcctcaga gagtttttaa tctttcagaa accacgggga
2401 ttctaacctt agggaaagca ctggacaggg aaagcactga tcgctacatt ctgatcatca
2461 cagcttcaga tggcaggcca gatgggacct caactgccac agtaaacata gtggtgacag
2521 atgtcaatga caatgctcca gtgtttgatc cttatctgcc aagaaattta tctgtggtgg
2581 aagaagaagc caatgccttt gtgggtcaag taaaagcaac agaccctgat gctggaataa
2641 atggtcaagt gcactacagt ttgggtaact ttaataatct ttttcgtatc acatccaatg
2701 ggagcattta cacagcagtg aagcttaaca gagaagtcag ggactactat gaacttgttg
2761 ttgtggcaac agatggagca gtacaccctc gtcattcaac tctaaccttg gccatcaagg
2821 ttttggacat tgatgataac agtcctgtgt tcaccaattc aacatacact gtccttgttg
2881 aagagaattt gccagctggg actaccatcc ttcaaataga ggccaaagat gtcgaccttg
2941 gagcaaatgt gtcttaccgg ataagaagcc cagaagtgaa gcactttttt gcactacatc
3001 catttacagg agaactatcg cttttaagga gtttagatta tgaggcattt ccagaccaag
3061 aagcaagtat cacttttctg gtagaggcct ttgatattta tggaacaatg ccacctggta
3121 ttgctactgt cacagtgatt gtaaaggata tgaatgatta tcctcctgtc tttagtaaac
3181 gaatatacaa agggatggtg gctccggatg cagtcaaggg tacacctatc acaacagttt
3241 atgctgaaga tgcagaccct cctggattac ctgcaagtcg tgtgaggtat agagtagatg
3301 atgtacagtt tccttaccct gccagtattt ttgaagtgga agaagattct ggaagagtaa
3361 taacacgagt caatcttaat gaagaaccta caacaatttt taagttggtg gtggttgctt
3421 ttgatgatgg ggagcctgtg atgtccagca gtgccacagt gaagattctt gtcttacatc
3481 ctggtgagat cccacgcttc acacaggagg aatatagacc tcctccagta agtgaacttg
3541 ccaccaaagg gaccatggtt ggtgtaattt ctgctgctgc cattaatcaa agtattgtgt
3601 actccattgt ttcaggaaat gaagaagata catttggaat taataacatc acaggtgtta
3661 tctatgtgaa tggacctctg gattatgaga ccaggacaag ctatgtactt cgagtccaag
3721 ctgattccct ggaagtggtc cttgccaatc tccgagttcc ttcaaaaagc aatacagcta
3781 aagtatacat tgagattcag gatgaaaata atcatccccc agtgtttcag aaaaaattct
3841 acatcggagg tgtatctgaa gatgcaagaa tgtttacttc tgtactcaga gtgaaggcta
3901 ctgataaaga tactggcaat tatagtgtca tggcctacag actcataata ccaccaatta
3961 aagagggaaa agaaggattt gtagtggaaa catatacagg gcttatcaaa actgctatgc
4021 tcttccataa tatgaggaga tcctacttca agtttcaagt tattgcaact gacgactatg
4081 ggaagggact gagcggcaaa gccgatgtac tcgtctccgt ggtcaatcag ctggatatgc
4141 aagtcattgt ttccaatgtg cctcctactc tagtggaaaa aaagatagaa gatcttacag
4201 agatcttgga tcgctatgtt caggaacaaa ttcctggtgc caaggtcgta gtggagtcca
4261 ttggagctcg ccggcatgga gatgcctttt ccctagaaga ttacaccaaa tgtgacttga
4321 ctgtctatgc aattgacccc caaaccaaca gagccatcga tagaaatgag ctttttaaat
4381 ttttggatgg caaactactt gatatcaata aagactttca gccgtattat ggggaaggag
4441 gacgcattct ggagatccgg actccagagg cagtgaccag cattaaaaag agaggagaaa
4501 gtctaggata cacagaaggg gccttgttgg ctctggcctt catcatcatc ctctgctgca
4561 ttcctgccat cttggtggtt ttggtcagct acagacagtt taaagtacgt caagctgagt
4621 gtacaaagac tgcacgaatt caggccgcat tacccgcggc taaaccagca gtgccggctc
4681 ctgcaccagt ggcagcgccc ccgccgccgc cgccgcctcc gccaggtgcg catctctatg
4741 aagaacttgg agacagctca attcttttcc ttctctacca ttttcaacaa agcaggggaa
4801 ataactcagt ctcagaagac aggaaacatc aacaagttgt gatgcccttt tcttccaata
4861 ctattgaggc tcacaagtca gctcatgtag acggatcact taagagcaac aaactgaagt
4921 ctgcaagaaa attcacattt ctatctgatg aggatgactt aagtgcccat aatccccttt
4981 ataaggaaaa cataagtcaa gtatcaacaa attcagacat ttcacagaga acagattttg
5041 tagacccatt ttcacccaaa atacaagcca agagtaagtc tctgaggggc ccaagagaaa
5101 agattcagag gctgtggagt cagtcagtca gcttacccag gaggctgatg aggaaagttc
5161 caaatagacc agagatcata gatctgcagc agtggcaagg caccaggcag aaagctgaaa
5221 atgaaaacac tggaatctgt acaaacaaaa gaggtagcag caatccattg cttacaactg
5281 aagaggcaaa tttgacagag aaagaggaaa taaggcaagg tgaaacactg atgatagaag
5341 gaacagaaca gttgaaatct ctctcttcag actcttcatt ttgctttccc aggcctcact
5401 tctcattctc cactttgcca actgtttcaa gaactgtgga actcaaatca gaacctaatg
5461 tcatcagttc tcctgctgag tgttccttgg aactttctcc ttcaaggcct tgtgttttac
5521 attcttcact ctctaggaga gagacaccta tttgtatgtt acctattgaa accgaaagaa
5581 atatttttga aaattttgcc catccaccaa acatctctcc ttctgcctgt ccccttcccc
5641 ctcctcctcc tatttctcct ccttctcctc ctcctgctcc tgctcctctt gctcctcctc
5701 ctgacatttc tcctttttct cttttttgtc ctcctccctc tcctccttct atccctcttc
5761 ctcttcctcc tcctacattt tttccacttt ccgtttcaac gtctggtccc ccaacaccac
5821 ctcttctacc tccatttcca actcctcttc ctccaccacc tccttctatt ccttgccctc
5881 cacctccttc agcttcattt ctgtccacag agtgtgtctg tataacaggt gttaaatgca
5941 cgaccaactt gatgcctgcc gagaaaatta agtcctctat gacacagcta tcaacaacga
6001 cagtgtgtaa aacagaccct cagagagaac caaaaggcat cctcagacac gttaaaaact
6061 tagcagaact tgaaaaatca gtagctaaca tgtacagtca aatagaaaaa aactatctac
6121 gcacaaatgt ttcagaactt caaactatgt gcccttcaga agtaacaaat atggaaatca
6181 catctgaaca aaacaagggg agtttgaaca atattgtcga gggaactgaa aaacaatctc
6241 acagtcaatc tacttcactg taatgttgct tttcttattt tagtcgggca aacctcttgt
6301 tgatcatagt cttcaagttg aacatcaaat ttgaacgtca aagaagactc tattatttta
6361 ccccaaattc aatgaaatgc agtttttttt ctcgttttta atttaaaaag atattaacct
6421 catcactact aactcactca tataatagat ttaccttact ttttaaaaac tacaaagtag
6481 cataatttgt tctacattta tttgaaaagt aagtaatttt aatctctttt ttagtgggaa
6541 tatgtgggca tgaaaattag atacccaact taaaccaaag gcatgtctat catgtggatg
6601 cagtaacatt tacatttagt ttttgatcgt agttttatat gaatgttcca agaaaaaagc
6661 agactgttac aaataagtta aaactgatat gattgatagg ttctgttttt tcttgaagcc
6721 tatgtatttg gtaagaagaa atactaccga agtaaaatat aatgtaccta gattgtagga
6781 gatgacagac ataaggtatt tcaaaataaa tctcaggtgc tataacatgt agtcatctgt
6841 tttct
//