LOCUS AY026038 549 bp mRNA linear HUM 11-NOV-2001 DEFINITION Homo sapiens K-Cl cotransporter (SLC12A4) mRNA, partial cds. ACCESSION AY026038 VERSION AY026038.1 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 549) AUTHORS Casula,S., Shmukler,B.E., Wilhelm,S., Stuart-Tilley,A.K., Su,W., Chernova,M.N., Brugnara,C. and Alper,S.L. TITLE A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity JOURNAL J. Biol. Chem. 276 (45), 41870-41878 (2001) PUBMED 11551954 REFERENCE 2 (bases 1 to 549) AUTHORS Shmukler,B.E., Wilhelm,S. and Alper,S.L. TITLE Direct Submission JOURNAL Submitted (26-JAN-2001) Molecular Medicine Unit, Beth Israel Deaconless Medical Center, 330 Brookline Ave., RW-663, Boston, MA 02215, USA FEATURES Location/Qualifiers source 1..549 /db_xref="H-InvDB:HIT000083221" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="16" /map="16q22.1" /cell_line="293T" gene <1..549 /gene="SLC12A4" /gene_synonym="KCC1" CDS <1..294 /gene="SLC12A4" /gene_synonym="KCC1" /note="cotransporter; exon 18 deletion terminates product inside exon 19" /codon_start=1 /product="K-Cl cotransporter" /protein_id="AAK01946.1" /translation="PPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIV GSVIQGSFLESYGEAQAAEQTPCAALRLPTWPCSCPRTSPSTPATTSATWRAT" BASE COUNT 111 a 168 c 163 g 107 t ORIGIN 1 cctcctcaca ccaagaactg gcggccgcag ctgctggtgc tgctgaagct ggacgaggac 61 ctccacgtga agtacccgcg gctcctcacc ttcgcctccc agctcaaggc tggcaagggc 121 ctgaccattg ttggttctgt catccagggg agcttcttgg agagctatgg cgaggctcag 181 gccgccgagc agacaccgtg cgctgcacta cggctgccca cctggccctg ctcgtgccca 241 agaacatcgc cttctacccc agcaaccacg agcgctacct ggagggccac atagacgtgt 301 ggtggatcgt gcacgatggt ggcatgctca tgcttctgcc cttcctgctg cgccagcata 361 aggtctggag gaagtgccgg atgcgcatct tcacagtggc ccagatggat gacaacagca 421 tccagatgaa gaaggacctg gctgtctttc tgtaccatct gcgccttgag gccgaggtgg 481 aggtggtgga gatgcataac agtgacatct ctgcatacac ctacgagcgg acactgatga 541 tggagcagc //