LOCUS AY016009 1410 bp mRNA linear HUM 18-JAN-2001
DEFINITION Homo sapiens junctional adhesion molecule 2 (JAM2) mRNA, complete
cds.
ACCESSION AY016009
VERSION AY016009.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1410)
AUTHORS Cunningham,S.A., Arrate,M.P., Rodriguez,J.M., Bjercke,R.J.,
Vanderslice,P., Morris,A.P. and Brock,T.A.
TITLE A novel protein with homology to the junctional adhesion molecule.
Characterization of leukocyte interactions
JOURNAL J. Biol. Chem. 275 (44), 34750-34756 (2000)
PUBMED 10945976
REFERENCE 2 (bases 1 to 1410)
AUTHORS Cunningham,S.A., Arrate,M.P. and Tran,T.M.
TITLE Direct Submission
JOURNAL Submitted (04-DEC-2000) Pharmacology, Texas Biotechnology
Corporation, Suite 1920, 7000 Fannin St., Houston, Texas 77030, USA
FEATURES Location/Qualifiers
source 1..1410
/db_xref="H-InvDB:HIT000083212"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q21.2"
/tissue_type="placenta"
gene 1..1410
/gene="JAM2"
CDS 235..1131
/gene="JAM2"
/codon_start=1
/product="junctional adhesion molecule 2"
/protein_id="AAG49022.1"
/translation="MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQ
EAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRS
DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEG
NPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN
SVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKS
NSSSKATTMSENDFKHTKSFII"
misc_feature 526..528
/gene="JAM2"
/note="glycosylation site"
misc_feature 793..795
/gene="JAM2"
/note="glycosylation site"
misc_feature 940..942
/gene="JAM2"
/note="glycosylation site"
misc_feature 943..996
/gene="JAM2"
/note="transmembrane region"
misc_feature 1069..1071
/gene="JAM2"
/note="phosphorylation site"
misc_feature 1117..1128
/gene="JAM2"
/note="potential PDZ binding motif"
misc_feature 235..294
/gene="JAM2"
/note="signal peptide"
misc_structure 382..561
/gene="JAM2"
/note="immunoglobulin-like fold 1"
misc_structure 697..876
/gene="JAM2"
/note="immunoglobulin-like fold 2"
BASE COUNT 422 a 341 c 305 g 342 t
ORIGIN
1 aaaacagaac agacccccat ccctgggctg gaggacccgc ctcttggcag ccagctgaga
61 aggcgccccg gggaggggga aactgacatc ccatctagag ccgtccctcc tcttcctccc
121 ctcccgactc tctgctcctt tcccgcccca gaagttcaag ggcccccggc ctcctgcgct
181 cctgccgcag ggaccctcga cctcctcaga gcagccggct gccgccccgg gaagatggcg
241 aggaggagcc gccaccgcct cctcctgctg ctgctgcgct acctggtggt cgccctgggc
301 tatcataagg cctatgggtt ttctgcccca aaagaccaac aagtagtcac agcagtagag
361 taccaagagg ctattttagc ctgcaaaacc ccaaagaaga ctgtttcctc cagattagag
421 tggaagaaac tgggtcggag tgtctccttt gtctactatc aacagactct tcaaggtgat
481 tttaaaaatc gagctgagat gatagatttc aatatccgga tcaaaaatgt gacaagaagt
541 gatgcgggga aatatcgttg tgaagttagt gccccatctg agcaaggcca aaacctggaa
601 gaggatacag tcactctgga agtattagtg gctccagcag ttccatcatg tgaagtaccc
661 tcttctgctc tgagtggaac tgtggtagag ctacgatgtc aagacaaaga agggaatcca
721 gctcctgaat acacatggtt taaggatggc atccgtttgc tagaaaatcc cagacttggc
781 tcccaaagca ccaacagctc atacacaatg aatacaaaaa ctggaactct gcaatttaat
841 actgtttcca aactggacac tggagaatat tcctgtgaag cccgcaattc tgttggatat
901 cgcaggtgtc ctgggaaacg aatgcaagta gatgatctca acataagtgg catcatagca
961 gccgtagtag ttgtggcctt agtgatttcc gtttgtggcc ttggtgtatg ctatgctcag
1021 aggaaaggct acttttcaaa agaaacctcc ttccagaaga gtaattcttc atctaaagcc
1081 acgacaatga gtgaaaatga tttcaagcac acaaaatcct ttataattta aagactccac
1141 tttagagata caccaaagcc accgttgtta cacaagttat taaactatta taaaactctg
1201 ctttgtccga catttgcaaa gaggtacacg aggaaatgga attggtattt cattttaatt
1261 ttcatgacta ctaactcacc tgaacttgct attttaaaca aatagttctg tcgacaccta
1321 aaatataatc tggcttcttg tgtctggact aagttaaaag aattaaaata ctttgtaatg
1381 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//