LOCUS AY009951 3539 bp mRNA linear HUM 03-DEC-2000
DEFINITION Homo sapiens hedgehog-interacting protein mRNA, complete cds.
ACCESSION AY009951
VERSION AY009951.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3539)
AUTHORS Huo,L., Roessler,E., Dutra,A., Chuang,P.T., McMahon,A.P. and
Muenke,M.
TITLE Determination of the chromosomal location and genomic structure of
the Hedgehog-Interacting Protein gene, and analysis of its role in
Holoprosencephaly
JOURNAL Gene Funct. Dis. (2000) In press
REFERENCE 2 (bases 1 to 3539)
AUTHORS Huo,L., Roessler,E., Dutra,A., Chuang,P.T., McMahon,A.P. and
Muenke,M.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-2000) Medical Genetics Branch, National Human
Genome Research Institute, 10 Center Drive, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..3539
/db_xref="H-InvDB:HIT000083169"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q32.1"
CDS 656..2758
/codon_start=1
/product="hedgehog-interacting protein"
/protein_id="AAG34731.1"
/translation="MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNP
PKRLKRRDRRMMSQLELLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTE
CGKLLEEIKCALCSPHSQSLFHSPEREVLERDIVLPLLCKDYCKEFFYTCRGHIPGFL
QTTADEFCFYYARKDGGLCFPDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFC
IQEVVSGLRQPVGALHSGDGSQRLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGI
KGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQV
DLRTARIFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMITLDDMEEMDGLSDFTGSV
LRLDVDTDMCNVPYSIPRSNPHFNSTNQPPEVFAHGLHDPGRCAVDRHPTDININLTI
LCSDSNGKNRSSARILQIIKGKDYESEPSLLEFKPFSNGPLVGGFVYRGCQSERLYGS
YVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTSGSCRGYFSGHILGFGEDELGEVYILS
SSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLCRNGYCTPTGKCC
CSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGIL
DQIIDMTSYLLDLTSYIV"
BASE COUNT 976 a 815 c 800 g 948 t
ORIGIN
1 tcgcgcgggg gccgccccct ccccttccct ccaccctggg cgggggcgcg cgagaagcgg
61 tgacgtcaag gggcgcgctg tggcagcacc tccccgcgcg ctagttaaaa agaagaagaa
121 aagagggaac gaaacatgag aggctgtgtg agaagctgca gccgccggca gaggagacct
181 cagcatcatc tagagcccag cgctggccct gcctccgcct gccccgccgc cgccgtcgcc
241 gtttctgttc ctgctactgt cccacctaaa caactcccgt tacacggaca agtgaacatc
301 tgtggctgtc ctctcctttt cttcctcctc ttccaactcc ttctcctcct cccacttccc
361 agccgcagca gaaagccccc aacccaactg acactggcac aactgcaaac ggtgtcatcc
421 gcacaacttt atctcgctcc tcgggctccc ctaaggcatt ggacccatcg ccgcgtcttt
481 tattttttgc aaagttgcat cgctgtacat atttttgtcc ccgccacctc cctctgtctc
541 tggagtgccc tacagccccg caaactcctc ctggagctgc gccctagtgc ccctgctggg
601 cagtggcgtt cccccccatc ctcccgcgcc cagcccctgc tgctctgggc agacgatgct
661 gaagatgctc tcctttaagc tgctgctgct ggccgtggct ctgggcttct ttgaaggaga
721 tgctaagttt ggggaaagaa acgaagggag cggagcaagg aggagaaggt gcctgaatgg
781 gaaccccccg aagcgcctga aaaggagaga caggaggatg atgtcccagc tggagctgct
841 gagtggggga gagatgctgt gcggtggctt ctaccctcgg ctgtcctgct gcctgcggag
901 tgacagcccg gggctagggc gcctggagaa taagatattt tctgttacca acaacacaga
961 atgtgggaag ttactggagg aaatcaaatg tgcactttgc tctccacatt ctcaaagcct
1021 gttccactca cctgagagag aagtcttgga aagagacata gtacttcctc tgctctgcaa
1081 agactattgc aaagaattct tttacacttg ccgaggccat attccaggtt tccttcaaac
1141 aactgcggat gagttttgct tttactatgc aagaaaagat ggtgggttgt gctttccaga
1201 ttttccaaga aaacaagtca gaggaccagc atctaactac ttggaccaga tggaagaata
1261 tgacaaagtg gaagagatca gcagaaagca caaacacaac tgcttctgta ttcaggaggt
1321 tgtgagtggg ctgcggcagc ccgttggtgc cctgcatagt ggggatggct cgcaacgtct
1381 cttcattctg gaaaaagaag gttatgtgaa gatacttacc cctgaaggag aaattttcaa
1441 ggagccttat ttggacattc acaaacttgt tcaaagtgga ataaagggag gagatgaaag
1501 aggactgcta agcctcgcat tccatcccaa ttacaagaaa aatggaaagt tgtatgtgtc
1561 ctataccacc aaccaagaac ggtgggctat cgggcctcat gaccacattc ttagggttgt
1621 ggaatacaca gtatccagaa aaaatccaca ccaagttgat ttgagaacag ccagaatctt
1681 tcttgaagtt gcagaactcc acagaaagca tctgggagga caactgctct ttggccctga
1741 cggctttttg tacatcattc ttggtgatgg gatgattaca ctggatgata tggaagaaat
1801 ggatgggtta agtgatttca caggctcagt gctacggctg gatgtggaca cagacatgtg
1861 caacgtgcct tattccatac caaggagcaa cccacacttc aacagcacca accagccccc
1921 cgaagtgttt gctcatgggc tccacgatcc aggcagatgt gctgtggata gacatcccac
1981 tgatataaac atcaatttaa cgatactgtg ttcagactcc aatggaaaaa acagatcatc
2041 agccagaatt ctacagataa taaaggggaa agattatgaa agtgagccat cacttttaga
2101 attcaagcca ttcagtaatg gtcctttggt tggtggattt gtataccggg gctgccagtc
2161 agaaagattg tatggaagct acgtgtttgg agatcgtaat gggaatttcc taactctcca
2221 gcaaagtcct gtgacaaagc agtggcaaga aaaaccactc tgtctcggca ctagtgggtc
2281 ctgtagaggc tacttttccg gtcacatctt gggatttgga gaagatgaac taggtgaagt
2341 ttacatttta tcaagcagta aaagtatgac ccagactcac aatggaaaac tctacaaaat
2401 tgtagatccc aaaagacctt taatgcctga ggaatgcaga gccacggtac aacctgcaca
2461 gacactgact tcagagtgct ccaggctctg tcgaaacggc tactgcaccc ccacgggaaa
2521 gtgctgctgc agtccaggct gggaggggga cttctgcaga actgcaaaat gtgagccagc
2581 atgtcgtcat ggaggtgtct gtgttagacc gaacaagtgc ctctgtaaaa aaggatatct
2641 tggtcctcaa tgtgaacaag tggacagaaa catccgcaga gtgaccaggg caggtattct
2701 tgatcagatc attgacatga catcttactt gctggatcta acaagttaca ttgtatagtt
2761 tctgggactg tttgaatatt ctattccaat gggcatttaa ttttttatcc tgtcattaaa
2821 aaaaaaagac tgttatcctg ctacacactc ctgtgatttc attctctttt attaatttaa
2881 aaataatttc cagaaatgtg cagatcctct gtgtgtatgt cagcatgttt gttcacatat
2941 gcacatacac atactcataa cccctatatg cgttgttgca taacagatga ttttttaaaa
3001 tatatacttc cttatgcaaa gtaatttaca cagaaattcc attgtaaatt gataatggat
3061 tttttatgtt actagaagag attatttgac ttcccaggaa ttttctgtct gtaatcacta
3121 aagtcaactt taatagagtt ttgaaacagt actgtgcaat ccgatggatc taattaaaaa
3181 aaaggcaata tttttatatt aaagtactat actaggagag aatgtttcag aactccctga
3241 tgaatttcta agtgagcaac ttgatataaa attgtaatct tcatttttgt cagtgtatcc
3301 agttacagaa tgctacacac ttaccttttt attggctgag aaatctggtt atttcatctt
3361 aatctcaaga ttgttttcaa gtgttttata attaaatcat aatagcatat tttaaaatca
3421 atcttcctaa aaggtctgct tttattgtat attttattta acaataggca ctgggtttgt
3481 gttacatatt tatatatttt attttatttt tataatatag acatcaccta gccggaatt
//