LOCUS       AY004872                 439 bp    mRNA    linear   HUM 18-AUG-2003
DEFINITION  Homo sapiens thioredoxin (TXN) mRNA, complete cds.
ACCESSION   AY004872
VERSION     AY004872.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Yegorova,S., Liu,A. and Lou,M.F.
  TITLE     Human lens thioredoxin: molecular cloning and functional
            characterization
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 44 (8), 3263-3271 (2003)
   PUBMED   12882768
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Liu,A. and Lou,M.F.
  TITLE     Cloning, purification and characterization of human lens
            thioredoxin
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 439)
  AUTHORS   Liu,A. and Lou,M.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUL-2000) Veterinary & Biomedical Sciences,
            University of Nebraska at Lincoln, 120 VBS, East Campus, Lincoln,
            NE 68583-0905, USA
FEATURES             Location/Qualifiers
     source          1..439
                     /db_xref="H-InvDB:HIT000082773"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /cell_line="HLE_B3"
                     /cell_type="epithelial"
                     /tissue_type="lens"
     gene            1..439
                     /gene="TXN"
     CDS             11..328
                     /gene="TXN"
                     /note="oxidoreductase"
                     /codon_start=1
                     /product="thioredoxin"
                     /protein_id="AAF87085.1"
                     /translation="MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHS
                     LSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATIN
                     ELV"
BASE COUNT          138 a           78 c           95 g          128 t
ORIGIN      
        1 agcagccaag atggtgaagc agatcgagag caagactgct tttcaggaag ccttggacgc
       61 tgcaggtgat aaacttgtag tagttgactt ctcagccacg tggtgtgggc cttgcaaaat
      121 gatcaagcct ttctttcatt ccctctctga aaagtattcc aacgtgatat tccttgaagt
      181 agatgtggat gactgtcagg atgttgcttc agagtgtgaa gtcaaatgca tgccaacatt
      241 ccagtttttt aagaagggac aaaaggtggg tgaattttct ggagccaata aggaaaagct
      301 tgaagccacc attaatgaat tagtctaatc atgttttctg aaaatataac cagccattgg
      361 ctatttaaaa cttgtaattt ttttaattta caaaaatata aaatatgaag acataaaccc
      421 agttgccatc tgcgtgaca
//