LOCUS AM177179 4866 bp mRNA linear HUM 15-OCT-2008
DEFINITION Homo sapiens mRNA for kinesin-like protein KIF21A variant (KIF21A
gene).
ACCESSION AM177179
VERSION AM177179.1
KEYWORDS KIF21A gene; kinesin-like protein KIF21A variant.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4866)
AUTHORS Lederer C.W.
JOURNAL Submitted (09-DEC-2005) to the INSDC. Lederer C.W., Department of
Biological Sciences, University of Cyprus, 75 Kallipoleos Avenue,
1678 Nicosia, CYPRUS.
REFERENCE 2
AUTHORS Pantelidou M., Lederer C.W., Zographos S.E., Pfaffl M.W.,
Cavallaro S., Santama N.
TITLE Differential expression analysis of molecular motors in ALS motor
neuron disease
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..4866
/db_xref="H-InvDB:HIT000331470"
/organism="Homo sapiens"
/mol_type="mRNA"
/sex="M"
/dev_stage="Adult"
/tissue_type="Motor cortex"
/db_xref="taxon:9606"
CDS 1..4866
/gene="KIF21A"
/product="kinesin-like protein KIF21A variant"
/db_xref="GOA:Q7Z4S6"
/db_xref="H-InvDB:HIT000331470.10"
/db_xref="HGNC:HGNC:19349"
/db_xref="InterPro:IPR001680"
/db_xref="InterPro:IPR001752"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR017986"
/db_xref="InterPro:IPR019775"
/db_xref="InterPro:IPR019821"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR027640"
/db_xref="InterPro:IPR036322"
/db_xref="InterPro:IPR036961"
/db_xref="PDB:5D3A"
/db_xref="PDB:5NFD"
/db_xref="PDB:5YBU"
/db_xref="PDB:5YBV"
/db_xref="UniProtKB/Swiss-Prot:Q7Z4S6"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAJ45483.1"
/translation="MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLG
KDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGF
DVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLF
DTTRDIDAKSKRSNIGIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTGSTQ
MNVQSSRSHAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLA
GSERLKRTGATGERAKEGISINCGLLALGNVISALGDKCKRATHVPYRDSKLTRLLQD
SLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSE
ITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALR
SRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLT
RATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNT
DTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSES
DEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLE
RDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYE
KQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKGQRKRDVTALR
RQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASGTGAQQKMRIPVARVQAS
PTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRL
LKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQA
NIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLE
GRLKRTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDA
PLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYAGSSELASDTSTGDASL
PGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSP
VTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTS
VQQDKGIINPFPASKGIRAFPLQCINIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWN
LVTGHRIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSAQV
TLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLT
GHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIE
ALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRG
GILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISD
TGDLGEDIASN"
BASE COUNT 1668 a 918 c 1140 g 1140 t
ORIGIN
1 atgttgggcg ccccggacga gagctccgtg cgggtggctg tcagaataag accacagctt
61 gccaaagaga agattgaagg atgccatatt tgtacatctg tcacaccagg agagcctcag
121 gtcttcctag ggaaagataa ggcttttact tttgactatg tatttgacat tgactcccag
181 caagagcaga tctacattca atgtatagaa aaactaattg aaggttgctt tgaaggatac
241 aatgctacag tttttgctta tggacaaact ggagctggta aaacatacac aatgggaaca
301 ggatttgatg ttaacattgt tgaggaagaa ctgggtatta tttctcgagc tgttaaacac
361 ctttttaaga gtattgaaga aaaaaaacac atagcaatta aaaatgggct tcctgctcca
421 gattttaaag tgaatgccca attcttagag ctctataatg aagaggtcct tgacttattt
481 gataccactc gtgatattga tgcaaaaagt aaaagatcaa atataggaat tcatgaagat
541 tcaactggag gaatttatac tgtgggcgtt acaacacgta ctgtgaatac agaatcagag
601 atgatgcagt gtttgaagtt gggtgcttta tcccggacaa ctggcagtac ccagatgaat
661 gttcagagct ctcgttcaca tgccattttt accattcatg tgtgtcaaac cagagtgtgt
721 ccccaaatag atgctgacaa tgcaactgat aataaaatta tttctgaatc agcacagatg
781 aatgaatttg aaaccctgac tgcaaagttc cattttgttg atctcgcagg atctgaaaga
841 ctgaagcgta ctggagctac aggcgagagg gcaaaagaag gcatttctat caactgtgga
901 cttttggcac ttggcaatgt aataagtgcc ttgggagaca agtgcaagag ggccacacat
961 gtcccctata gagattccaa gctaacaaga ctactacagg attccctcgg gggtaatagc
1021 caaacaatca tgatagcatg tgtcagccct tcagacagag actttatgga aacgttaaac
1081 accctgaaat acgccaatcg agctagaaat atcaagaata aggtgatggt caatcaggac
1141 agagctagtc agcaaatcaa tgcacttcgt agtgaaatca cacgacttca gatggagctc
1201 atggagtaca aaacaggtaa aagaataatt gacgaagagg gtgtggaaag catcaatgac
1261 atgtttcatg agaatgctat gctacagact gaaaataata acctgcgtgt aagaattaaa
1321 gccatgcaag agacggttga tgcattgagg tccagaatta cacagcttgt tagtgatcag
1381 gccaaccatg ttcttgccag agcaggtgaa ggaaatgagg agattagtaa tatgattcat
1441 agttatataa aagaaatcga agatctcagg gcaaaattat tagaaagtga agcagtgaat
1501 gagaaccttc gaaaaaactt gacaagagcc acagcaagag cgccatattt cagcggatca
1561 tcaacttttt ctcctaccat actatcctca gacaaagaaa ccattgaaat tatagaccta
1621 gcaaaaaaag atttagagaa gttgaaaaga aaagaaaaga ggaagaaaaa aagtgtggct
1681 ggtaaagagg ataatacaga cactgaccaa gagaagaaag aagaaaaggg tgtttcggaa
1741 agagaaaaca atgaattaga agtggaagaa agtcaagaag tgagtgatca tgaggatgaa
1801 gaagaggagg aggaggagga ggaagatgac attgatgggg gtgaaagttc tgatgaatca
1861 gattctgaat cagatgaaaa agccaattat caagcagact tggcaaacat tacttgtgaa
1921 attgcaatta agcaaaagct gattgatgaa ctagaaaaca gccagaaaag actgcagact
1981 ctgaaaaagc agtatgaaga gaagctaatg atgctgcaac ataaaattcg ggatactcag
2041 cttgaaagag accaggtgct tcaaaactta ggctcggtag aatcttactc agaagaaaaa
2101 gcaaaaaaag ttaggtctga atatgaaaag aaactccaag ccatgaacaa agaactgcag
2161 agacttcaag cagctcaaaa agaacatgca aggttgctta aaaatcagtc tcagtatgaa
2221 aagcaattga agaaattgca gcaggatgtg atggaaatga aaaaaacaaa ggttcgccta
2281 atgaaacaaa tgaaagaaga acaagagaaa gccagactga ctgagtctag aagaaacaga
2341 gagattgctc agttgaaaaa gggtcaacgt aaaagagatg ttacggctct tcgtcggcaa
2401 gtaagaccca tgtcagataa agtggctggg aaagttactc ggaagctgag ttcatctgat
2461 gcacctgctc aggacacagg ttccagtgca gctgctgtgg aaacagatgc atcagggaca
2521 ggagcccagc agaaaatgag aattcctgtg gcgagagtcc aggcctcacc aacgccggca
2581 acaaatggaa acaggaaaaa atatcagagg aaaggattga ctggccgagt gtttatttcc
2641 aagacagctc gcatgaagtg gcagctcctt gagcgcaggg tcacagacat catcatgcag
2701 aagatgacca tttccaacat ggaggcagat atgaatagac tcctcaagca acgggaggaa
2761 ctcacaaaaa gacgagagaa actttcaaaa agaagggaga agatagtcaa ggagaatgga
2821 gagggagata aaaatgtggc taatatcaat gaagagatgg agtcactgac tgctaatatc
2881 gattacatca atgacagtat ttctgattgt caggccaaca taatgcagat ggaagaagca
2941 aaggaagaag gtgagacatt ggatgttact gcagtcatta atgcctgcac ccttacagaa
3001 gcccgatacc tgctagatca cttcctgtca atgggcatca ataagggtct tcaggctgcc
3061 cagaaagagg ctcaaattaa agtactggaa ggtcgactca aacgaacaga aataaccagt
3121 gctacccaaa accagctctt attccatatg ttgaaagaga aggcagaatt aaatcctgag
3181 ctagatgctt tactaggcca tgctttacaa gatctagata gcgtaccatt agaaaatgta
3241 gaggatagta ctgatgagga tgctccttta aacagcccag gatcagaagg aagcacgctg
3301 tcttcagatc tcatgaagct ttgtggtgaa gtgaaaccta agaacaaggc ccgaaggaga
3361 accaccactc agatggaatt gctgtatgca ggtagcagtg aactagcttc agacactagt
3421 acaggagatg cctccttgcc tggccctctc acacctgttg cagaagggca agagattgga
3481 atgaatacag agacaagtgg tacttctgct agggaaaaag agctctctcc cccacctggc
3541 ttaccttcta agataggcag catttccagg cagtcatctc tatcagaaaa aaaaattcca
3601 gagccttctc ctgtaacaag gagaaaggca tatgagaaag cagaaaaatc aaaggccaag
3661 gaacaaaagc actcagattc tggaacttca gaggctagtc tttcacctcc ttcttcccca
3721 ccaagccggc cccgtaatga actgaatgtt tttaatcgtc ttactgtttc tcagggaaac
3781 acatcagttc agcaggataa gggcataatc aacccatttc ctgcttcaaa aggaatcaga
3841 gcttttccac ttcagtgtat aaacatagct gaagggcata caaaagctgt gctctgtgtg
3901 gattctactg atgatctcct cttcactgga tcaaaagatc gtacttgtaa agtatggaat
3961 ctggtgactg ggcacaggat aatgtcactg gggggtcatc ccaacaatgt cgtgtctgta
4021 aaatactgta attacaccag tttggtcttc actgtatcaa catcttatat taaggtgtgg
4081 gatatcagag attcagcaaa gtgcattcga acactaacgt cttcagctca agttactctt
4141 ggagatgctt gttctgcaag taccagtcga acagtagcta ttccttctgg agagaaccag
4201 atcaatcaaa ttgccctaaa cccaactggc accttcctct atgctgcttc tggaaatgct
4261 gtcaggatgt gggatcttaa aaggtttcag tctacaggaa agttaacagg acacctaggc
4321 cctgttatgt gccttactgt ggatcagatt tccagtggac aagatctaat catcactggc
4381 tccaaggatc attacatcaa aatgtttgat gttacagaag gagctcttgg gactgtgagt
4441 cccacccaca attttgaacc ccctcattat gatggcatag aagcactaac cattcaaggg
4501 gataacctat ttagtgggtc tagagataat ggaatcaaga aatgggactt aactcaaaaa
4561 gaccttcttc agcaagttcc aaatgcacat aaggattggg tctgtgccct gggagtggtg
4621 ccagaccacc cagttttgct cagtggctgc agagggggca ttttgaaagt ctggaacatg
4681 gatactttta tgccagtggg agagatgaag ggtcatgata gtcctatcaa tgccatatgt
4741 gttaattcca cccacatttt tactgcagct gatgatcgaa ctgtgagaat ttggaaggct
4801 cgcaatttgc aagatggtca gatctctgac acaggagatc tgggggaaga tattgccagt
4861 aattga
//