LOCUS AL133623 8281 bp mRNA linear HUM 15-OCT-2008
DEFINITION Homo sapiens mRNA; cDNA DKFZp434P0721 (from clone DKFZp434P0721);
partial cds.
ACCESSION AL133623
VERSION AL133623.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8281)
AUTHORS Blum H., Bauersachs S., Mewes H.W., Gassenhuber J., Wiemann S.
JOURNAL Submitted (15-DEC-1999) to the INSDC. MIPS, Am Klopferspitz 18a,
D-82152 Martinsried, GERMANY
COMMENT Clone from S. Wiemann, Molecular Genome Analysis, German Cancer
Research Center (DKFZ); Email s.wiemann@dkfz-heidelberg.de;
sequenced by LMU (Ludwig Maximilians University,
Munich/Germany) within the cDNA sequencing consortium of the
German Genome Project.
This clone (DKFZp434P0721) is available at the RZPD in Berlin.
Please contact the RZPD: Ressourcenzentrum, Heubnerweg 6,
14059 Berlin-Charlottenburg, GERMANY; Email: clone@rzpd.de
Further information about the clone and the sequencing project
is available at http://www.mips.biochem.mpg.de/proj/cDNA/
FEATURES Location/Qualifiers
source 1..8281
/db_xref="H-InvDB:HIT000025090"
/organism="Homo sapiens"
/map="3"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="434 (synonym: htes3). Vector pSport1; host
DH10B; sites NotI + SalI"
/clone="DKFZp434P0721"
/tissue_type="testis"
/db_xref="taxon:9606"
CDS <1..3481
/codon_start=2
/gene="DKFZp434P0721"
/product="hypothetical protein"
/note="strong similarity to mouse 5'-3' exonuclease"
/db_xref="GOA:Q8IZH2"
/db_xref="H-InvDB:HIT000025090.15"
/db_xref="HGNC:HGNC:30654"
/db_xref="InterPro:IPR004859"
/db_xref="InterPro:IPR016494"
/db_xref="InterPro:IPR027073"
/db_xref="InterPro:IPR040992"
/db_xref="InterPro:IPR041106"
/db_xref="InterPro:IPR041385"
/db_xref="InterPro:IPR041412"
/db_xref="UniProtKB/Swiss-Prot:Q8IZH2"
/protein_id="CAB63749.1"
/translation="TNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDERLLEAME
TCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAW
RVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVD
AESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRT
APPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQN
GEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGC
TGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYL
VSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQ
LLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLS
RSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDA
EFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPG
RGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQ
SLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGF
NDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEV
QSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNR
RDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSR
ICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLG
SLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGK
PFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQ
PDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSR
KLAVNFGVSKPSE"
regulatory 8205..8210
/regulatory_class="polyA_signal_sequence"
polyA_site 8227
BASE COUNT 2618 a 1449 c 1526 g 2688 t
ORIGIN
1 gaccaatgaa gactcaccaa ttatagaata ttacccacct gattttaaaa ctgacctaaa
61 tgggaaacaa caggaatggg aagctgtggt gttaatccct tttattgatg agcgattatt
121 ggaagccatg gagacatgta accactccct caaaaaggaa gagaggaaaa gaaaccaaca
181 tagtgagtgc ctaatgtgct ggtatgatag agacacagag tttatctatc cttctccatg
241 gccagaaaag ttccctgcca tagaacgatg ttgtacaagg tataaaataa tatccttaga
301 tgcttggcgt gtagacataa acaaaaacaa aataaccaga attgaccaga aagcattata
361 tttctgtgga tttcctactc tgaaacacat cagacacaaa ttttttttga agaaaagtgg
421 tgttcaagta ttccagcaaa gcagtcgtgg agaaaacatg atgttggaaa tcttagtgga
481 tgcagaatca gatgaactta ccgtagaaaa tgtagcttca tcagtgcttg gaaaatctgt
541 ctttgttaat tggcctcacc ttgaggaagc tagagtcgtg gctgtatcag atggagaaac
601 taagttttac ttggaagaac ctccaggaac acagaagctt tattcaggaa gaactgcccc
661 accatctaaa gtggttcatc ttggagataa agaacaatct aactgggcaa aagaagtaca
721 aggaatttca gaacactacc tgagaagaaa aggaataata ataaatgaaa catctgcagt
781 tgtgtatgct cagttactca caggtcgtaa atatcaaata aatcaaaatg gtgaagttcg
841 tctagagaaa cagtggtcaa aacaagttgt tccttttgtt tatcaaacta ttgtcaagga
901 catccgagct ttcgactccc gtttctccaa tatcaaaaca ttggatgatt tgtttcctct
961 gagaagtatg gtctttatgc tgggaactcc ctattatggc tgcactggag aagttcagga
1021 ttcaggtgat gtgattacag aaggtaggat tcgtgtgatt ttcagcattc catgtgaacc
1081 caatcttgat gctttaatac agaaccagca taaatattct ataaagtaca acccaggata
1141 tgtgttggcc agtcgccttg gagtgagtgg ataccttgtt tcaaggttta caggaagtat
1201 ttttattgga agaggatcta ggagaaaccc tcatggagac cataaagcaa atgtgggttt
1261 aaatctcaaa ttcaacaaga aaaatgagga ggtacctgga tatactaaga aagttggaag
1321 tgaatggatg tattcatctg cagcagaaca acttctggca gagtacttag agagagctcc
1381 agaactattt agttatatag ccaaaaatag ccaagaggat gtgttctatg aagatgacat
1441 ttggcctgga gaaaatgaga atggtgctga aaaagttcaa gaaattatta cttggctaaa
1501 aggacatcct gtcagtactt tatctcgttc ttcttgtgat ttacaaattc tggatgcagc
1561 tattgttgag aaaattgagg aagaagtcga aaagtgcaag caaagaaaga ataataagaa
1621 ggtgcgagta acagtgaaac cccatttgct atacagacct ttagaacagc aacatggagt
1681 cattcctgat cgggatgcag aattttgtct ttttgaccgt gttgtaaatg tgagagaaaa
1741 cttctcagtt ccagttggcc ttcgaggcac catcatagga ataaaaggag ctaatagaga
1801 agccgatgta ctatttgaag tattatttga tgaagaattt cctggagggt taacaataag
1861 atgctcacct ggtagaggtt atcgactgcc aacaagtgcc ttggtgaacc tttctcatgg
1921 gagtcgctct gaaactggaa atcagaagtt gacagccatc gtaaaaccac aaccagctgt
1981 acatcaacat agctcaagtt catcagtttc ctctgggcat ttgggagccc tcaaccattc
2041 ccctcaatca ctttttgttc ctactcaagt acctactaaa gatgatgatg aattctgcaa
2101 catttggcag tccttacagg gatctggaaa gatgcaatac tttcagccaa ctatacaaga
2161 gaagggtgca gttctacctc aagaaataag ccaagtaaat caacatcata aatctggctt
2221 taatgacaac agtgttaaat atcagcaaag aaaacatgac cctcacagaa aatttaaaga
2281 agagtgtaag agtcctaaag ctgagtgttg gtcccaaaaa atgtccaata agcagcctaa
2341 ctctggaatt gagaactttt tagcatcttt gaatatctcc aaagaaaatg aagtacagtc
2401 atctcatcat ggggagcctc caagtgaaga gcatttgtca ccacagtcat ttgccatgaa
2461 gggaacacgg atgcttaaag aaattctaaa aattgatggc tctaacactg tggaccataa
2521 gaatgaaatc aaacagattg ctaatgaaat ccctgtttcc tctaacagaa gagatgaata
2581 tggattaccc tctcagccta aacaaaataa gaaattagca tcttatatga acaagcctca
2641 cagtgctaat gagtaccata atgttcagtc tatggacaat atgtgttggc ctgcccccag
2701 ccagatccct cctgtatcca caccagtaac tgaactttct cgaatttgtt cccttgttgg
2761 aatgccacaa cctgatttct cctttcttag gatgccacag acaatgaccg tttgccaagt
2821 aaaattatct aatggcttac tggtacatgg gccacagtgc cactctgaaa atgaagccaa
2881 agagaaagct gcactttttg ctttacaaca gttgggctcc ttaggcatga atttcccttt
2941 gccttcacaa gtatttgcaa attatccttc agctgtacca cctggaacca ttcctccagc
3001 ctttccccca cctactgcta atataatgcc ttcgtcgtct catctctttg gctcaatgcc
3061 atggggacca tcggtgccag ttcctgggaa gcccttccat catactttat attctgggac
3121 catgcccatg gctgggggaa taccaggggg tgtgcacaat cagtttatac ctctgcaggt
3181 tactaaaaaa agggttgcaa acaaaaagaa ctttgagaat aaggaagccc agagttctca
3241 agccactcca gttcagacta gccagccaga ttcttccaac attgtcaaag taagtccacg
3301 ggagagctca tcagcttctt tgaagtcctc tccgattgct caacctgcat cttcttttca
3361 agttgaaact gcctctcaag gccatagtat atctcaccat aagtcaacac caatctcttc
3421 ttcaagaaga aaatcaagaa aactggctgt taattttggt gtttctaaac cttctgagta
3481 aatttggctc ttagaattaa gttaatttct tctctttcca tctacctttt tataaataca
3541 tatctatgtc tcataaaaat tagaatgtac tattttaaaa taatatgtgt aaattgaaat
3601 ttttttcatt tttaagttat caggcacttt tcatgctgtt taaaagactg tgtatcaaat
3661 tgtgcacttt aagtatgtgc agtttgttgt atgtcaatta tacctcaata aatctgtaat
3721 aaaaaactaa attaaacctt gcattaaaat aatatcacag tatcagtgga ctaaacatta
3781 aaatgtacca ctctaatcat tggcctcatg attgaagcat cctgaactat gaattagaca
3841 tcagttagca ataataagca ttttttacac tatcattgag gaataattac atggagcatg
3901 aaatttgggc ctccagtata acttactgaa tgtggatttt atttctcttt ttaatgatgt
3961 aagaaaattg tcaggagaat ggctcttatt tatgtgtgtt ttaacttatg ctttgttgcc
4021 tctgagggtc tttagacctg ctgtgaaagg atcacatttg ttgtggtgct gccagttttg
4081 ctttattcta aattttgtac caaagcaact ttagaataat cagaatattt catctaactg
4141 cttagaacta taaatagcat tctaaatttg agtaaataca attttttagg ttactcaaga
4201 accagcatta gtaatttcta gtaaaattgt ttcaaaatct acagggtaca atgattacaa
4261 attaatcttc taacaaaata aaatatgaaa tattagtcat gttaattaat aaactgtatt
4321 attttgtata gctttttatt tgcttacctg acattttatg agagcttcat agttggtcgg
4381 tatgtagtgc ttcttgggac tgaagaaatt ctaattgttg tttaagttcc aaggtgtgct
4441 acaatatagg aggcacagtc atcagtttgt gacatacatt atttactgcc tatttcattc
4501 tgattctata tttttagctt tatgctgaac tgttcaatga tgctgggatt ctctctttgc
4561 atgtcatatg tgaatgtgtg gttcaagctg taactgttga aattatttta gaatttatga
4621 cgatttctca gcagggccta tgtttatata tatatatata tttattcttt agtttttgtg
4681 atatgcttat atttttaagg aagtaagtta tagcatactt ttttaaaagt aggaaccaca
4741 atctttatat ggagcagctt gttatatctg attttcatgt aactcattgg aaactctgcc
4801 atgactctta aagtagtctt acttgttttt taaaatgctg gtattaaact aaatggactc
4861 ctttcactaa ctgctgattt cagagtttaa atgttagcag gatatttgtg tattagcagt
4921 gccttcagta taagagagaa atattcatta tctgtcattt atcatagtcg tataagtttc
4981 catgatttta ttttctgtta ttttcataag ttcagatgtt tatcagttcc caacattgtt
5041 tctttatctg tagtgggatc ttgagtaatg aggctcaagt aaatcctcaa tgtgtataat
5101 tattgcctca taaactctct ctttgttttt aaaggaaaca tctattatgg taatacaaag
5161 aaaagttaaa ttgtgacagt aatgttatat taacctcttc ctactttaaa gtgtgaaatg
5221 tttcacctca gctgtacaaa ctccagcatt gagaatttgc ctcactcatt actcctgtgt
5281 gacagttata taaatagcat gcagctcaca tctgttttag agcatagaag aagcggcacc
5341 tgccatcttc tgaaaactcc aaagggaaat ttcagtagac atagtgcact aaacccataa
5401 ggatacttga ccaatatttg agcacagcaa gctgacagtt ctatacagat aggcagtgaa
5461 agagttttat tttccagcca ggcgcagtgg ctcaaatccc agcacttcgg gaggctaagg
5521 caggcggatc acttgaggtc cggagttcca gacaagcctg gccaacatga tgaagccctg
5581 tctctactaa aaatacaaaa aaaaaaaaga aaaaagtttt attatcctta cttttttttt
5641 aacattatta ttctaaaggt caaaactgag aagagattaa gataggagag agctccataa
5701 tggctggata gtggtcaggc attctctatt cttttccccc tgtagaccca ttctaaatgt
5761 gggcctgagg tcaatgggag atgtgccctc cctatggagg atgtaagaag cagaggccat
5821 ttctgcccca tgttgaggaa acaatctgtt gatagacctg gaatttagag tacatctgaa
5881 aagcagttgg acttcaagaa atttaaaatt ctctctttga gatggggtgg actaagacca
5941 cccccaaagt ttaaaaatat gctcattcaa cttgaatctt ctgaggactt tttgtgaaaa
6001 tggtggactg tttagggcat aggacagatt ccccaaattg ctttatgctt ccacataact
6061 agagcacttc aatctattta agcctttgtc tcctaactga aacattattt ctaaatattt
6121 ctattcaata agttttttct tttttgagca acttaagtga attttgaaga ttgctccttc
6181 cagtctcgtt ccttttcaca ttttcctgca ttacctaata attacctcag cgttagaatt
6241 tgaatgtatt aattgattta aacatcatgt agactaaagt cttaaacatc taagactcag
6301 ttgtagttgc agaaaaaaat taaagtcacc tctactgaac cttggtttca atttaagatt
6361 tttcttgctt ttcaaagggg taactaataa agattgaagg gtttttttcc cgattggtgg
6421 aggaatgaag aactattgat gcaagttttt ttattgtttc tttctatgat caggtacctg
6481 ctttcatttt agactgctac ttccaaacta agctagattc ttggttttaa tgagaggagg
6541 cagagagagg gaggcagatg gaagaagaaa aacagttaaa taagacatac ccagtcactg
6601 catttttgga ctataccgta tctttctagc acaaggaaat agataaactg taaggtcttt
6661 tttactcact ttttatttat gtgttctatt tgtgttagtc ataactgttt atagtggttg
6721 tctaattttt acttttatta tatgagatag agctgtgcag atcttcactc aagttctgtc
6781 acgcttcttc ccattattta gagcacagtt ttttaaagca actgtacaat ttctcagcct
6841 tatgagcttg ctgtatttct tggtatcatg ttgcttccaa attttgtttt tactgtagaa
6901 gacaattaat ttattgtaga gaagtggctg tgaaagtcgt tctctgtctt taaaaatcaa
6961 ttgcagaagt tcatttgtca tttttctaga gataaattat agtactcaaa ctggcagtgc
7021 tcagtatata cattttgtaa gctttgtcag tgaaaccatc agttttgcag gagcttcctt
7081 tcctagtcaa gataaagctt aaaattccag aaattaatgt cgttcggact gactttattc
7141 atatttccat caaacttctc caatacagta agagatagtg ttgaaccagc atcaagtctc
7201 cagaaacatg gcagagcaga caggccgtta agtttcacag acatcataga tccttttctt
7261 aaagaagaaa aacatgtata aaatagtttt agtagtccaa aatgtcaact atctgtagct
7321 gcttttgtgt gtgtgtcagt gaacaaataa taatgccttg ctcaatcaat gcattcagcc
7381 atctcaagtg caatttgtga aggagactat ggtttccaaa agatacattt ttttacaaag
7441 ttaaacctgt aaaaagtctt tttttttttc cctccagccg tacaccaact gcacttggtt
7501 gtttcagcag ttggtatact attaaattgt ccaggccaaa taggtttctg tagctgtttt
7561 agtaatttga agccaaattc tcatgctgtt tctcattaaa aagaatgaga atttggtcca
7621 tagttagctt taagttctct cttcctttct ttcccttaca gttaagggtt tggtggggga
7681 tggggaggtt gttttcgttt tttggatttt tttgtctttt ggctttaagt atcatatttt
7741 cttttgcctg tatccaactg cttctttgag tattttcatc tagtttaatg tgagtaatag
7801 atgctgtgct gtcattgaag tgttcaacat tttgttcatt taaacaaaag tgtaattcat
7861 acatatatag atacatatct taattgattt ctcaactatt ttataagtaa ctggaatttt
7921 tcattagatc ttatacagag aagtatttta ttaaaaattc aaaagggaag acttttatgt
7981 gctcattttg taatttttga ttttaaatat ctttacattg tctgccaatt aaagtgtttt
8041 aaacttgcat tggaatggac tccgaatgta tttttgtggt gttacgttat ccgtagattt
8101 ctagcatgaa gttagcctca cgatgctgtg caaaggattt taaaatatga gagtcactga
8161 aagagtttaa acatctgttc atgttaaatg ctctatggat tttaattaaa gacttgagaa
8221 tgattttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
8281 g
//