LOCUS AK316074 2280 bp mRNA linear HUM 21-JAN-2009
DEFINITION Homo sapiens cDNA, FLJ78973 complete cds, highly similar to DNA
mismatch repair protein Mlh1.
ACCESSION AK316074
VERSION AK316074.1
KEYWORDS FLI_CDNA; oligo capping.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2280)
AUTHORS Isogai,T. and Yamamoto,J.
TITLE Direct Submission
JOURNAL Submitted (11-JAN-2008) to the DDBJ/EMBL/GenBank databases.
Contact:Takao Isogai
Reverse Proteomics Research Institute; 1-9-11 Kaji-cho,
Chiyoda-ku, Tokyo 101-0044, Japan
E-mail :flj-cdna@nifty.com
REFERENCE 2
AUTHORS Wakamatsu,A., Yamamoto,J., Kimura,K., Ishii,S., Watanabe,K.,
Sugiyama,A., Murakawa,K., Kaida,T., Tsuchiya,K., Fukuzumi,Y.,
Kumagai,A., Oishi,Y., Yamamoto,S., Ono,Y., Komori,Y., Yamazaki,M.,
Kisu,Y., Nishikawa,T., Sugano,S., Nomura,N. and Isogai,T.
TITLE NEDO human cDNA sequencing project
JOURNAL Unpublished (2008)
COMMENT Human cDNA sequencing project focused on splicing variants of mRNA
in NEDO functional analysis of protein and research application
project supported by Ministry of Economy, Trade and Industry,
Japan; cDNA selection for complete cds sequencing: Reverse
Proteomics Research Institute (REPRORI), Hitachi, Ltd., Japan
(Hitachi) and Japan Biological Informatics Consortium, Japan
(JBIC); cDNA complete cds sequencing: JBIC; cDNA library
construction: Helix Research Institute supported by Japan Key
Technology Center, Japan (HRI); cDNA 5'- & 3'-end sequencing:
Research Association for Biotechnology, Japan, Biotechnology
Center, National Institute of Technology and Evaluation, Japan and
HRI; cDNA mapping to human genome: Central Research Laboratory,
Hitachi; evaluation and annotation: REPRORI.
FEATURES Location/Qualifiers
source 1..2280
/clone="BRSSN2003214"
/clone_lib="BRSSN2"
/db_xref="H-InvDB:HIT000499687"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="cloning vector: pME18SFL3"
/organism="Homo sapiens"
/tissue_type="substantia nigra"
CDS 603..2150
/codon_start=1
/note="highly similar to DNA mismatch repair protein Mlh1"
/protein_id="BAH14445.1"
/transl_table=1
/translation="MNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLP
KNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMY
FTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLS
KPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMS
EKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQG
HEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLR
LSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEE
GNLIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYI
SEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDL
YKVFERC"
BASE COUNT 642 a 513 c 538 g 587 t
ORIGIN
1 gacgtgccag tcaggccttc tccttttccg cagaccgtgt gtttctttac cgctctcccc
61 cgagaccttt taagggttgt ttggagtttt agatgcaaaa tccacaagta ttcaagtgat
121 tgttaaagag ggaggcctga agttgattca gatccaagac aatggcaccg ggatcaggaa
181 agaagatctg gatattgtat gtgaaaggtt cactactagt aaactgcagt cctttgagga
241 tttagccagt atttctacct atggctttcg aggtgaggct ttggccagca taagccatgt
301 ggctcatgtt actattacaa cgaaaacagc tgatggaaag tgtgcataca gagcaagtta
361 ctcagatgga aaactgaaag cccctcctaa accatgtgct ggcaatcaag ggacccagat
421 cacggtattc agtacacaat gcaggcatta gtttctcagt taaaaaacaa ggagagacag
481 tagctgatgt taggacacta cccaatgcct caaccgtgga caatattcgc tccgtctttg
541 gaaatgctgt tagtcgagaa ctgatagaaa ttggatgtga ggataaaacc ctagccttca
601 aaatgaatgg ttacatatcc aatgcaaact actcagtgaa gaagtgcatc ttcttactct
661 tcatcaacca tcgtctggta gaatcaactt ccttgagaaa agccatagaa acagtgtatg
721 cagcctattt gcccaaaaac acacacccat tcctgtacct cagtttagaa atcagtcccc
781 agaatgtgga tgttaatgtg caccccacaa agcatgaagt tcacttcctg cacgaggaga
841 gcatcctgga gcgggtgcag cagcacatcg agagcaagct cctgggctcc aattcctcca
901 ggatgtactt cacccagact ttgctaccag gacttgctgg cccctctggg gagatggtta
961 aatccacaac aagtctgacc tcgtcttcta cttctggaag tagtgataag gtctatgccc
1021 accagatggt tcgtacagat tcccgggaac agaagcttga tgcatttctg cagcctctga
1081 gcaaacccct gtccagtcag ccccaggcca ttgtcacaga ggataagaca gatatttcta
1141 gtggcagggc taggcagcaa gatgaggaga tgcttgaact cccagcccct gctgaagtgg
1201 ctgccaaaaa tcagagcttg gagggggata caacaaaggg gacttcagaa atgtcagaga
1261 agagaggacc tacttccagc aaccccagaa agagacatcg ggaagattct gatgtggaaa
1321 tggtggaaga tgattcccga aaggaaatga ctgcagcttg taccccccgg agaaggatca
1381 ttaacctcac tagtgttttg agtctccagg aagaaattaa tgagcaggga catgaggttc
1441 tccgggagat gttgcataac cactccttcg tgggctgtgt gaatcctcag tgggccttgg
1501 cacagcatca aaccaagtta taccttctca acaccaccaa gcttagtgaa gaactgttct
1561 accagatact catttatgat tttgccaatt ttggtgttct caggttatcg gagccagcac
1621 cgctctttga ccttgccatg cttgccttag atagtccaga gagtggctgg acagaggaag
1681 atggtcccaa agaaggactt gctgaataca ttgttgagtt tctgaagaag aaggctgaga
1741 tgcttgcgga ctatttctct ttggaaattg atgaggaggg gaacctgatt ggattacccc
1801 ttctgattga caactatgtg ccccctttgg agggactgcc tatcttcatt cttcgactag
1861 ccactgaggt gaattgggac gaagaaaagg aatgttttga aagcctcagt aaagaatgcg
1921 ctatgttcta ttccatccgg aagcagtaca tatctgagga gtcgaccctc tcaggccagc
1981 agagtgaagt gcctggctcc attccaaact cctggaagtg gactgtggaa cacattgtct
2041 ataaagcctt gcgctcacac attctgcctc ctaaacattt cacagaagat ggaaatatcc
2101 tgcagcttgc taacctgcct gatctataca aagtctttga gaggtgttaa atatggttat
2161 ttatgcactg tgggatgtgt tcttctttct ctgtattccg atacaaagtg ttgtatcaaa
2221 gtgtgatata caaagtgtac caacataagt gttggtagca cttaagactt atacttgcct
//