LOCUS AK312341 2095 bp mRNA linear HTC 24-MAY-2008
DEFINITION Homo sapiens cDNA, FLJ92660, Homo sapiens proprotein convertase
subtilisin/kexin type 2 (PCSK2),mRNA.
ACCESSION AK312341
VERSION AK312341.1
KEYWORDS HTC; HTC_FLI; oligo capping.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2095)
AUTHORS Isogai,T. and Yamamoto,J.
TITLE Direct Submission
JOURNAL Submitted (11-JAN-2008) to the DDBJ/EMBL/GenBank databases.
Contact:Takao Isogai
Reverse Proteomics Research Institute; 1-9-11 Kaji-cho,
Chiyoda-ku, Tokyo 101-0044, Japan
E-mail :flj-cdna@nifty.com
REFERENCE 2
AUTHORS Wakamatsu,A., Yamamoto,J., Kimura,K., Kaida,T., Tsuchiya,K.,
Iida,Y., Takayama,Y., Murakawa,K., Kanehori,K., Andoh,T.,
Kagawa,N., Sato,R., Kawamura,Y., Tanaka,S., Kisu,Y., Sugano,S.,
Goshima,N., Nomura,N. and Isogai,T.
TITLE NEDO functional analysis of protein and research application
project
JOURNAL Unpublished (2008)
COMMENT Human cDNA sequencing project focused on splicing variants of mRNA
in NEDO functional analysis of protein and research application
project supported by Ministry of Economy, Trade and Industry,
Japan; cDNA selection for complete cds sequencing: Reverse
Proteomics Research Institute (REPRORI), Hitachi, Ltd., Japan
(Hitachi) and Japan Biological Informatics Consortium, Japan
(JBIC); cDNA complete cds sequencing: JBIC and Biological
Information Research Center (BIRC), AIST; cDNA library
construction: Helix Research Institute supported by Japan Key
Technology Center, Japan (HRI); cDNA 5'- & 3'-end sequencing:
Research Association for Biotechnology, Japan, Biotechnology
Center, National Institute of Technology and Evaluation, Japan and
HRI; cDNA mapping to human genome: Central Research Laboratory,
Hitachi; evaluation and annotation: REPRORI.
FEATURES Location/Qualifiers
source 1..2095
/clone="BRALZ2010211"
/clone_lib="BRALZ2"
/db_xref="H-InvDB:HIT000431207"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="cloning vector: pME18SFL3"
/organism="Homo sapiens"
/tissue_type="alzheimer cortex"
CDS 179..2095
/note="Homo sapiens proprotein convertase
subtilisin/kexin type 2 (PCSK2),mRNA"
/protein_id="BAG35262.1"
/translation="MKGGCVSQWKAAAGFLFCVMVFASAERPVFTNHFLVELHKGGED
KARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQE
GFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKG
VTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSA
AANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGK
TVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSA
INDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAG
VFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAG
AMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQ
AVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARG
TWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELD
EAVERSLKSILNKN"
BASE COUNT 518 a 563 c 584 g 430 t
ORIGIN
1 agatgctgga gaacacacac tgattcgctg ctttccaaga ccctgttcag tctctttctc
61 tatacaaaga tttttttaaa aactatatat aagaattctt tatttgcacc ctccctccga
121 gtcccctgct ccgccagcct gcgcgcctcc tagcaccact tttcactccc aaagaaggat
181 gaagggtggt tgtgtctccc agtggaaggc ggccgccggg ttcctcttct gtgtcatggt
241 ttttgcatct gctgagcgac cggtcttcac gaatcatttt cttgtggagt tgcataaagg
301 gggagaggac aaagctcgcc aagttgcagc agaacacggc tttggagtcc gaaagcttcc
361 ctttgctgaa ggtctgtacc acttttatca caatggcctt gcaaaggcca agagaagacg
421 cagcctacac cacaagcagc agctggagag agaccccagg gtaaagatgg ctttgcagca
481 ggaaggattt gaccgaaaaa agcgaggtta cagagacatc aatgagatcg acatcaacat
541 gaacgatcct ctttttacaa agcagtggta tctgatcaat actgggcaag ctgatggcac
601 tcctggcctt gatttgaatg tggctgaagc ctgggagctg ggatacacag ggaaaggtgt
661 taccattgga attatggatg atgggattga ctatctccac ccggacctgg cctccaacta
721 taatgccgaa gcaagttacg acttcagcag caacgacccc tatccttacc ctcggtacac
781 agatgactgg tttaacagcc acgggacccg atgtgcagga gaagtttctg ctgccgccaa
841 caacaatatc tgtggagttg gagtagcata caactccaag gttgcaggca tccggatgct
901 ggaccagcca ttcatgacag acatcatcga ggcctcctcc atcagtcata tgccacagct
961 gattgacatc tacagcgcca gctggggccc cacagacaac ggcaagacag tggatgggcc
1021 ccgggagctc acgctgcagg ccatggccga tggcgtgaac aagggccgcg gcggcaaagg
1081 cagcatctac gtgtgggcct ccggggacgg cggcagctat gacgactgca actgcgacgg
1141 ctacgcctcc agcatgtgga ccatctccat caactcagcc atcaacgacg gcaggactgc
1201 cctgtacgac gagagctgct cttccacctt ggcttccacc ttcagcaacg ggaggaaaag
1261 gaaccccgag gccggtgtgg caaccacaga tttgtacggc aactgcactc tgaggcattc
1321 tgggacatct gcagctgccc ccgaggcagc tggtgtgttt gcactggctc tggaggctaa
1381 cctgggtctg acctggcggg acatgcagca tctgactgtg ctcacctcca aacggaacca
1441 gcttcacgac gaggtccatc agtggcggcg caatggggtc ggcctggaat ttaatcacct
1501 ctttggctac ggggtccttg atgcaggtgc catggtgaaa atggctaaag actggaaaac
1561 cgtgcctgag agattccact gtgtgggagg ctccgtgcag gaccctgaga aaataccatc
1621 cactggcaag ttggtgctga cactcacaac cgacgcctgt gaggggaagg aaaattttgt
1681 ccgctacctg gagcatgtcc aggctgtcat cacggtcaac gcaaccagaa gaggagacct
1741 gaacatcaac atgacttccc ctatgggcac caagtccatt ttgctgagcc ggcgtccaag
1801 ggatgacgac tccaaggtgg gctttgacaa gtggcctttc atgaccactc acacgtgggg
1861 ggaagacgcc cgaggcacct ggaccctgga gctgggattt gtcggcagcg ccccgcagaa
1921 gggggtgctg aaggagtgga ccctgatgct gcatggcact cagagtgccc cgtacatcga
1981 ccaggtggtg cgggattacc agtccaagtt ggccatgtcc aagaaagagg agctggagga
2041 agagctggac gaagccgtgg agagaagcct gaaaagcatc cttaacaaga actag
//