LOCUS AK295610 4232 bp mRNA linear HUM 21-JAN-2009
DEFINITION Homo sapiens cDNA FLJ56564 complete cds, highly similar to
Mitogen-activated protein kinase kinase kinase kinase 4 (EC
2.7.11.1).
ACCESSION AK295610
VERSION AK295610.1
KEYWORDS FLI_CDNA; oligo capping.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4232)
AUTHORS Isogai,T. and Yamamoto,J.
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2007) to the DDBJ/EMBL/GenBank databases.
Contact:Takao Isogai
Reverse Proteomics Research Institute; 1-9-11 Kaji-cho,
Chiyoda-ku, Tokyo 101-0044, Japan
E-mail :flj-cdna@nifty.com
REFERENCE 2
AUTHORS Wakamatsu,A., Yamamoto,J., Kimura,K., Ishii,S., Watanabe,K.,
Sugiyama,A., Murakawa,K., Kaida,T., Tsuchiya,K., Fukuzumi,Y.,
Kumagai,A., Oishi,Y., Yamamoto,S., Ono,Y., Komori,Y., Yamazaki,M.,
Kisu,Y., Nishikawa,T., Sugano,S., Nomura,N. and Isogai,T.
TITLE NEDO human cDNA sequencing project focused on splicing variants
JOURNAL Unpublished (2007)
COMMENT Human cDNA sequencing project focused on splicing variants of mRNA
in NEDO functional analysis of protein and research application
project supported by Ministry of Economy, Trade and Industry,
Japan; cDNA selection for complete cds sequencing: Reverse
Proteomics Research Institute (REPRORI), Hitachi, Ltd., Japan
(Hitachi) and Japan Biological Informatics Consortium, Japan
(JBIC); cDNA complete cds sequencing: JBIC; cDNA library
construction: Helix Research Institute supported by Japan Key
Technology Center, Japan (HRI); cDNA 5'- & 3'-end sequencing:
Research Association for Biotechnology, Japan, Biotechnology
Center, National Institute of Technology and Evaluation, Japan and
HRI; cDNA mapping to human genome: Central Research Laboratory,
Hitachi; evaluation and annotation: REPRORI.
FEATURES Location/Qualifiers
source 1..4232
/clone="BRHIP3000300"
/clone_lib="BRHIP3"
/db_xref="H-InvDB:HIT000490234"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="cloning vector: pME18SFL3"
/organism="Homo sapiens"
/tissue_type="hippocampus"
CDS 31..3870
/codon_start=1
/note="highly similar to Mitogen-activated protein kinase
kinase kinase kinase 4 (EC 2.7.11.1)"
/protein_id="BAH12124.1"
/transl_table=1
/translation="MLQALQLRTGFFCFRVLVALSPCALHDSGRLTTGSFNVVRDEEE
EIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKG
NTLKEDWIAYISREILRGLAHLHIHHVIHRDVKGQNVLLTENAEVKLVDFGVSAQLDR
TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHP
MRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNER
QVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR
DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQ
QRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR
QLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAH
YEPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRREVLS
QSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAG
QRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSS
SKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDY
SSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVE
SEPAMTPSKEGTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSS
PSSSQPTPTMSPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTT
VTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCA
ALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLR
VYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIHGSCAGFHAVDVDSGSVYD
IYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTS
VAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGG
SSQVYFMTLGRTSLLSW"
BASE COUNT 1183 a 992 c 1103 g 954 t
ORIGIN
1 ctattctgtt attcctcaga ggccagctaa atgctacagg ccttacagct tcgtactggc
61 ttcttctgtt ttagggtgtt ggtggcactt tctccctgtg ctttgcatga ctctggcaga
121 cttaccacag gatcattcaa cgttgtcagg gatgaagagg aagaaatcaa actggagata
181 aatatgctaa agaaatactc tcatcacaga aacattgcaa catattatgg tgctttcatc
241 aaaaagagcc ctccaggaca tgatgaccaa ctctggcttg ttatggagtt ctgtggggct
301 gggtccatta cagaccttgt gaagaacacc aaagggaaca cactcaaaga agactggatc
361 gcttacatct ccagagaaat cctgagggga ctggcacatc ttcacattca tcatgtgatt
421 caccgggatg tcaagggcca gaatgtgttg ctgactgaga atgcagaggt gaaacttgtt
481 gactttggtg tgagtgctca gctggacagg actgtggggc ggagaaatac gttcataggc
541 actccctact ggatggctcc tgaggtcatc gcctgtgatg agaacccaga tgccacctat
601 gattacagaa gtgatctttg gtcttgtggc attacagcca ttgagatggc agaaggtgct
661 ccccctctct gtgacatgca tccaatgaga gcactgtttc tcattcccag aaaccctcct
721 ccccggctga agtcaaaaaa atggtcgaag aagtttttta gttttataga agggtgcctg
781 gtgaagaatt acatgcagcg gccctctaca gagcagcttt tgaaacatcc ttttataagg
841 gatcagccaa atgaaaggca agttagaatc cagcttaagg atcatataga tcgtaccagg
901 aagaagagag gcgagaaaga tgaaactgag tatgagtaca gtgggagtga ggaagaagag
961 gaggaagtgc ctgaacagga aggagagcca agttccattg tgaacgtgcc tggtgagtct
1021 actcttcgcc gagatttcct gagactgcag caggagaaca aggaacgttc cgaggctctt
1081 cggagacaac agttactaca ggagcaacag ctccgggagc aggaagaata taaaaggcaa
1141 ctgctggcag agagacagaa gcggattgag cagcagaaag aacagaggcg acggctagaa
1201 gagcaacaaa ggagagagcg ggaagctaga aggcagcagg aacgtgaaca gcgaaggaga
1261 gaacaagaag aaaagaggcg tctagaggag ttggagagaa ggcgcaaaga agaagaggag
1321 aggagacggg cagaagaaga aaagaggaga gttgaaagag aacaggagta tatcaggcga
1381 cagctagaag aggagcagcg gcacttggaa gtccttcagc agcagctgct ccaggagcag
1441 gccatgttac tgcatgacca taggaggccg cacccgcagc actcgcagca gccgccacca
1501 ccgcagcagg aaaggagcaa gccaagcttc catgctcccg agcccaaagc ccactacgag
1561 cctgctgacc gagcgcgaga ggtacagtgg tcccacctgg catctctcaa gaacaatgtt
1621 tcccctgtct cgcgatccca ttccttcagt gacccttctc ccaaatttgc acaccaccat
1681 cttcgttctc aggacccatg tccaccttcc cgcagagagg tgctcagtca gagctctgac
1741 tctaagtcag aggcgcctga ccctacccaa aaggcttggt ctagatcaga cagtgacgag
1801 gtgcctccaa gggttcctgt gagaacaaca tctcgctccc ctgttctgtc ccgtcgagat
1861 tccccactgc agggcagtgg gcagcagaat agccaggcag gacagagaaa ctccaccagc
1921 agtattgagc ccaggcttct gtgggagaga gtggagaagc tggtgcccag acctggcagt
1981 ggcagctcct cagggtccag caactcagga tcccagcccg ggtctcaccc tgggtctcag
2041 agtggctccg gggaacgctt cagagtgaga tcatcatcca agtctgaagg ctctccatct
2101 cagcgcctgg aaaatgcagt gaaaaaacct gaagataaaa aggaagtttt cagacccctc
2161 aagcctgctg gcgaagtgga tctgaccgca ctggccaaag agcttcgagc agtggaagat
2221 gtacggccac ctcacaaagt aacggactac tcctcatcca gtgaggagtc ggggacgacg
2281 gatgaggagg acgacgatgt ggagcaggaa ggggctgacg agtccacctc aggaccagag
2341 gacaccagag cagcgtcatc tctgaatttg agcaatggtg aaacggaatc tgtgaaaacc
2401 atgattgtcc atgatgatgt agaaagtgag ccggccatga ccccatccaa ggagggcact
2461 ctaatcgtcc gccagagtac agttgaccaa aagcgtgcca gccatcatga gagcaatggc
2521 tttgccggtc gcattcacct cttgccagat ctcttacagc aaagccattc ctcctccact
2581 tcctccacct cctcctcccc atcctccagc cagccgacac ccaccatgtc cccacagaca
2641 ccccaggaca agctcactgc taatgagact cagtccgcta gtagcacact ccagaaacac
2701 aaatcttcct cctcctttac accttttata gaccccagat tactacagat ttctccatct
2761 agcggaacaa cagtgacatc tgtggtggga ttttcctgtg atgggatgag accagaagcc
2821 ataaggcaag atcctacccg gaaaggctca gtggtcaatg tgaatcctac caacactagg
2881 ccacagagtg acaccccgga gattcgtaaa tacaagaaga ggtttaactc tgagattctg
2941 tgtgctgcct tatggggagt gaatttgcta gtgggtacag agagtggcct gatgctgctg
3001 gacagaagtg gccaagggaa ggtctatcct cttatcaacc gaagacgatt tcaacaaatg
3061 gacgtacttg agggcttgaa tgtcttggtg acaatatctg gcaaaaagga taagttacgt
3121 gtctactatt tgtcctggtt aagaaataaa atacttcaca atgatccaga agttgagaag
3181 aagcagggat ggacaaccgt aggggatttg gaaggatgtg tacattataa agttgtaaaa
3241 tatgaaagaa tcaaatttct ggtgattgct ttgaagagtt ctgtggaagt ctatgcgtgg
3301 gcaccaaagc catatcacaa atttatggcc tttaagtcat ttggagaatt ggtacataag
3361 ccattactgg tggatctcac tgttgaggaa ggccagaggt tgaaagtgat ccatggatcc
3421 tgtgctggat tccatgctgt tgatgtggat tcaggatcag tctatgacat ttatctacca
3481 acacatatcc agtgtagcat caaaccccat gcaatcatca tcctccccaa tacagatgga
3541 atggagcttc tggtgtgcta tgaagatgag ggggtttatg taaacacata tggaaggatc
3601 accaaggatg tagttctaca gtggggagag atgcctacat cagtagcata tattcgatcc
3661 aatcagacaa tgggctgggg agagaaggcc atagagatcc gatctgtgga aactggtcac
3721 ttggatggtg tgttcatgca caaaagggct caaagactaa aattcttgtg tgaacgcaat
3781 gacaaggtgt tctttgcctc tgttcggtct ggtggcagca gtcaggttta tttcatgacc
3841 ttaggcagga cttctcttct gagctggtag aagcagtgtg atccagggat tactggcctc
3901 cagagtcttc aagatcctga gaacttggaa ttccttgtaa ctggagctcg gagctgcacc
3961 gagggcaacc aggacagctg tgtgtgcaga cctcatgtgt tgggttctct cccctccttc
4021 ctgttcctct tatataccag tttatcccca ttcttttttt ttttcttact ccaaaataaa
4081 tcaaggctgc aatgcagctg gtgctgttca gattctacca tcaggtgcta taagtgtttg
4141 ggattgagca tcatactgga aagcaaacac ctttcctcca gctccagaat tccttgtctc
4201 tgaatgactc tgtcttgtgg gtgtctgaca gt
//