LOCUS AJ628419 2541 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for type II hair keratin 2 (KRTHB2 gene).
ACCESSION AJ628419
VERSION AJ628419.1
KEYWORDS KRTHB2 gene; type II hair keratin 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2541)
AUTHORS Rogers M.A.
JOURNAL Submitted (20-FEB-2004) to the INSDC. Rogers M.A., Research Program
A145, German Cancer Research Center, Im Neuenheimer Feld 280,
Baden-Wurttemberg, 69120, GERMANY.
REFERENCE 3
AUTHORS Rogers M.A., Winter H., Langbein L., Wolf C., Schweizer J.
TITLE Characterization of a 300 kbp region of human DNA containing the
type II hair keratin gene domain
JOURNAL J. Invest. Dermatol. 114(3), 464-472(2000).
PUBMED 10692104
REFERENCE 4
AUTHORS Rogers M.A., Edler L., Winter H., Langbein L., Beckmann I.,
Schweizer J.
TITLE Characterization of new members of the human type II keratin gene
family and a general evaluation of the keratin gene domain on
chromosome 12q13.13
JOURNAL J. Invest. Dermatol. 124(3), 536-544(2005).
PUBMED 15737194
FEATURES Location/Qualifiers
source 1..2541
/db_xref="H-InvDB:HIT000249322"
/organism="Homo sapiens"
/chromosome="12"
/map="12q13.13"
/mol_type="mRNA"
/clone="12-5cdna"
/tissue_type="human scalp"
/db_xref="taxon:9606"
CDS 79..1620
/gene="KRTHB2"
/product="type II hair keratin 2"
/function="structural protein"
/db_xref="GOA:Q701L7"
/db_xref="H-InvDB:HIT000249322.14"
/db_xref="InterPro:IPR003054"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR032444"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/TrEMBL:Q701L7"
/protein_id="CAF31523.1"
/translation="MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGR
GLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLL
VPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC
CQTNIEPILEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCV
ENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVK
MDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKN
EILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKA
KQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFL
YEPCGVSMPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSS
PSHKH"
BASE COUNT 600 a 730 c 706 g 505 t
ORIGIN
1 gggaagctga gcctgacttg atcatcctgc cccggttctt tcctccaggg ccgcatttct
61 ctgcctctct ctcctgccat gtcgtaccac tctttccagc caggctccag gtgtggcagt
121 cagagtttca gctcatactc ggctgtcatg ccccggatgg tcacccacta tgcagtgagc
181 aaggggccat gccggcccgg gggtggtagg ggcctccgag ctctgggctg ccttggctca
241 cggagcctgt gcaacgtggg ctttgggagg ccccgggtag cctccaggtg tggaggtacc
301 ctgcctggct tcgggtaccg actgggagcc acctgtgggc cttctgcctg catcacccct
361 gtcaccatca atgagagcct gctggtccca ctggcactgg agatagaccc gactgtgcag
421 agggtaaaga gggatgagaa ggagcagatc aagtgcctca acaaccgttt cgcatctttc
481 atcaacaagg tccgtttcct ggagcagaag aacaagctgc tggagaccaa gtggaacttc
541 atgcagcagc agaggtgctg ccagaccaac atcgagccca tcctcgaggg ctatatcagc
601 gcccttcggc ggcagctgga ctgtgtgtcc ggggaccgcg tgaggctaga gtcagagctc
661 tgcagcctcc aggctgcact ggagggctac aagaaaaaat acgaagagga gctctccctg
721 cgtccctgtg ttgagaatga gtttgttgcc ttgaagaagg acgtggacac agccttcctg
781 atgaaggctg acctggagac caacgcagag gcactcgtgc aggagatcga cttcctgaaa
841 agcctgtatg aggaggagat ctgcctgctc cagtctcaga tctctgagac ctcggtcatt
901 gtgaagatgg acaacagccg ggagctggac gtggacggca tcatcgctga gatcaaggcg
961 cagtatgacg acatcgccag ccgcagcaaa gccgaagcag aggcctggta ccagtgccgg
1021 tatgaggagc tgagagtcac agctgggaac cactgtgaca acctccgcaa ccgtaagaac
1081 gagatcctgg aaatgaataa actgatccag cggctgcagc aagaaaccga gaatgtcaaa
1141 gcccagcgct gcaaacttga gggtgccata gctgaggcag agcagcaggg cgaggcggct
1201 ctcaatgatg ccaagtgcaa gctggcaggg ctggaggagg ctctgcagaa ggccaagcag
1261 gacatggcct gcctgctcaa ggaatatcag gaggtgatga actccaagct gggcctggac
1321 atcgagatcg ccacctacag gcgcctgctg gagggtgaag agcacaggct gtgcgaaggc
1381 atcgggcccg tgaatatctc agtgagcagc tccaaaggcg ccttcctgta cgagccatgt
1441 ggggtcagca tgcctgtcct cagcactggc gtcctcagga gcaatggggg ctgcagcatc
1501 gtgggcactg gtgaactcta tgtcccctgc gagccccagg ggctactgag ctgtgggagc
1561 gggcggaaat ccagcatgac gctaggagct gggggcagct cccccagcca caagcattag
1621 catgatccga gacatccagg agacagagcc cctgccccat ggccctggat gtcacacccc
1681 caccagggct gaagacaagg atgttccaaa accccacctc cctttattga ctccacattc
1741 ccctccagtg ttccctcctt gagagctgag ctgcccctag gacccctcct ttgcctcatg
1801 agtcaccttc cactcacctg tgtgcagacc ctcagctagg cccagatggt ggggacagac
1861 ggcagagaaa gagcatgcat tgctcttaac cgcagaatgg caataacccc caaaaggtca
1921 aatgggcaca ccacagttct gctctgtgga tcatcccatg gaagtttcct cacaaagtca
1981 gctcctctcc caccacaggc tcacactgcc cttactttag gctctcatgc ccctaagaaa
2041 agtgaatttc ctttaacacc gcctgaaaca tgcacgctgc aaatatcaaa aggagacacc
2101 cccaaatccc actctaaatt ccaaagccaa gtgccacgat ttcaggatca gtcaggacct
2161 gccaatgtcc tctcagcaca gagaatcaag aggtggcctt tgggcagtag atttactttc
2221 tcaggtatgt tgaacccaaa ctgtgagaat aaatctttct cctgagctca cattggcagg
2281 tgatgtcagg ccaatgccta gaacaaaggg caaagggata tggaatgttt actggacagt
2341 tggaaaacca aaaacagata ccatttgctc aatggaatca gttccccctc cacccatccc
2401 cttctgtaca tagccgcccc ttcctgttcc ccaacccttt agctcctttt gctttgagtc
2461 tgatatgaca gtgatgtggg gctgccccag ctgacttgga ggccctggct caggagctca
2521 tagatggagg aggtgtgggc t
//