LOCUS AJ626900 6474 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for Xin A (CMYA1 gene).
ACCESSION AJ626900
VERSION AJ626900.1
KEYWORDS cardiomyopathy associated 1; CMYA1 gene; Xin A.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6474)
AUTHORS Fuerst D.O.
JOURNAL Submitted (30-JAN-2004) to the INSDC. Fuerst D.O., Cell Biology,
University of Potsdam, Lennestr. 7a, D-14471 Potsdam, GERMANY.
REFERENCE 2
AUTHORS Van der Ven P.F.M., Vakeel P., Eulitz S., Fuerst D.O.
TITLE A long splice variant of human xin encodes a novel adapter protein
involved in actin regulation
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..6474
/db_xref="H-InvDB:HIT000249288"
/organism="Homo sapiens"
/chromosome="3p21.33"
/mol_type="mRNA"
/tissue_type="cross-striated muscle"
/db_xref="taxon:9606"
CDS 230..5761
/gene="CMYA1"
/product="Xin A"
/function="actin-binding adapter protein"
/note="splice variant: A"
/db_xref="GOA:Q702N8"
/db_xref="H-InvDB:HIT000249288.13"
/db_xref="HGNC:HGNC:14301"
/db_xref="InterPro:IPR012510"
/db_xref="InterPro:IPR030072"
/db_xref="UniProtKB/Swiss-Prot:Q702N8"
/protein_id="CAF25192.1"
/translation="MADTQTQVAPTPTMRMATAEDLPLPPPPALEDLPLPPPKESFSK
FHQQRQASELRRLYRHIHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWR
LDAIGEHERPAAKEPVLCGDVQATSRKFEEGSFANSTDQEPTRPQPGGGDVRAARWLF
ETKPLDELTGQAKELEATVREPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELR
SEIQELKGDVKKTVKLFQTEPLCAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETR
PLDAINQDPSQVRVIRGISLEEGARPDVSATRWIFETQPLDAIREILVDEKDFQPSPD
LIPPGPDVQQQQHLFETRALDTLKGDEEAGAEAPPKEEVVPGDVRSTLWLFETKPLDA
FRDKVQVGHLQRVDPQDGEGHLSSDSSSALPFSQSAPQRDELKGDVKTFKNLFETLPL
DSIGQGEVLAHGSPSREEGTDSAGQAQGIGSPVYAMQDSKGRLHALTSVSREQIVGGD
VQGYRWMFETQPLDQLGRSPSTIDVVRGITRQEVVAGDVGTARWLFETQPLEMIHQRE
QQERQKEEGKSQGDPQPEAPPKGDVQTIRWLFETCPMSELAEKQGSEVTDPTAKAEAQ
SCTWMFKPQPVDRPVGSREQHLQVSQVPAGERQTDRHVFETEPLQASGRPCGRRPVRY
CSRVEIPSGQVSRQKEVFQALEAGKKEEQEPRVIAGSIPAGSVHKFTWLFENCPMGSL
AAESIQGGNLLEEQPMSPSGNRMQESQETAAEGTLRTLHATPGILHHGGILMEARGPG
ELCLAKYVLSGTGQGHPYIRKEELVSGELPRIICQVLRRPDVDQQGLLVQEDPTGQLQ
LKPLRLPTPGSSGNIEDMDPELQQLLACGLGTSVARTGLVMQETEQGLVALTAYSLQP
RLTSKASERSSVQLLASCIDKGDLSGLHSLRWEPPADPSPVPASEGAQSLHPTESIIH
VPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGM
AVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNP
IQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAH
PVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAW
GPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPA
AVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPP
KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPT
TVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPT
SPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQAL
RRLFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEE
AVHKALSSMSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVK
NQAKVECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPS
SPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQ
CSVQPEPAPPSASPLPRGWQKSVLELQTGPGSSQHYGAMRTVTEQYEEVDQFGNTVLM
SSTTVTEQAEPPRNPGSHLGLHASPLLRQFLHSPAGFSSDLTEAETVQVSCSYSQPAA
Q"
BASE COUNT 1535 a 2015 c 1847 g 1077 t
ORIGIN
1 cagagacctg gagccagggc agcaagaagg tgtctgttgg agccagcaga acagaaccaa
61 tttgaacaag aacctccaga ggaacgacga accctgagac cacagctgct acagaccaca
121 aacaccccat cagccaagag agacccttgc atccagcctc taccctgccg aacatctaga
181 tctaaggctc ccaatcccat cctcatctct gccccttctt ctcagaagga tggccgacac
241 ccagacacag gtggccccca caccaaccat gaggatggca actgcagagg acctgcccct
301 ccctccaccc ccagccctgg aggacctgcc actgccgcca cccaaggaat ccttctccaa
361 gttccatcag cagcggcaag ctagtgagct ccgccgcctc tacaggcaca tccaccctga
421 gctccgcaag aatctggctg aggctgtggc cgaggatctg gctgaggtcc tgggctctga
481 ggaacccacc gagggtgacg ttcagtgcat gcgctggatc tttgagaact ggagactgga
541 tgccattgga gaacacgaga ggccagctgc caaggagccc gtgctgtgtg gtgacgtcca
601 ggccacctcc cgcaagtttg aggaaggctc ctttgccaac agcacagacc aggagccaac
661 caggccccag ccaggtggag gagacgttcg tgcagcccgc tggctatttg agacaaagcc
721 actggacgag ctgacagggc aagccaagga actggaggcc actgtgaggg agcctgcagc
781 cagcggagat gtgcagggta ccaggatgct ctttgagacg cggccgctgg accgcctggg
841 ctcccgcccc tccctgcagg agcagagccc cttggaactg cgctcagaga tccaggagct
901 gaagggtgat gtgaaaaaga cagtgaagct cttccaaacg gagcccctgt gtgccatcca
961 ggatgcagag ggcgccatcc atgaggtcaa ggccgcatgc cgggaggaga tccaaagcaa
1021 cgcggtgagg tctgcccgct ggctctttga gacccggcct ctggacgcca tcaaccagga
1081 ccccagccag gtgcgggtga tccgggggat ttccctggag gagggggccc ggcccgacgt
1141 cagtgcaact cgctggatct ttgagacaca gcccctggat gccatccggg agatcttggt
1201 agatgagaag gacttccagc catccccaga ccttatccca cctggtccag atgttcagca
1261 gcagcagcat ctgtttgaga cccgagcgct ggacactctg aagggggacg aagaggctgg
1321 agcagaggcc ccacccaagg aggaagtggt ccctggtgat gtccgctcca ccctgtggct
1381 atttgaaaca aagcccctgg atgctttcag agacaaggtc caagtgggtc acctacagcg
1441 agtggatccc caggacggtg aggggcatct atccagtgac agctcctcag cactgccctt
1501 ctctcagagt gccccccaga gggatgagct aaagggggat gtgaagactt ttaagaacct
1561 ttttgagacc cttcccttgg acagcattgg acagggtgag gttctggccc atgggagtcc
1621 aagcagagaa gaaggaactg attctgctgg gcaggcccag ggcatagggt ccccagtgta
1681 tgccatgcag gacagcaagg gccgcctcca tgccctgacc tctgttagca gagagcagat
1741 agtcggaggt gatgtgcagg gctacaggtg gatgtttgag acacagcccc tagaccagct
1801 cggccgaagc cccagtacca tcgacgtggt gcggggcatc acccggcagg aagtggtggc
1861 tggggacgtt ggcacagctc ggtggctttt tgagacccag cccctggaga tgatccacca
1921 acgggagcag caggaacgac agaaagaaga agggaagagt cagggagacc cccagcctga
1981 ggcaccccca aagggcgatg tgcagaccat ccggtggttg ttcgagactt gcccaatgag
2041 tgagttggcc gaaaagcagg ggtcagaggt cacagatccc acagccaagg ctgaggcaca
2101 gtcctgcacc tggatgttca agccccaacc tgtggacagg ccagtgggct ccagggagca
2161 gcacctgcag gttagccagg tcccggctgg ggaaagacag acagacagac acgtctttga
2221 gaccgagcct cttcaggcct caggccgtcc ctgtggaaga cggcctgtga gatactgcag
2281 ccgcgtggag atcccttcag ggcaggtgtc tcgtcagaaa gaggtttttc aggccctgga
2341 ggcaggcaag aaggaagaac aggagccccg ggtaatcgct gggtccatcc ccgcgggttc
2401 tgtccacaag ttcacttggc tttttgagaa ttgtcccatg ggctccctgg cagctgagag
2461 catccaaggg ggcaacctcc tggaagagca gcccatgagc ccctcaggca acaggatgca
2521 agagagccag gagactgcag ctgaggggac cctgcggact ctgcatgcca cacctggcat
2581 cctgcaccat ggaggcatcc tcatggaggc ccgagggcca ggggagctct gtcttgccaa
2641 gtatgtgctc tcgggcacag ggcaggggca cccttatata cgaaaggagg agctggtgtc
2701 aggtgaactt cccaggatca tctgccaagt cctgcgccgg ccagatgtgg accagcaggg
2761 gctgctggtg caggaagacc caactggcca gctccaactc aagccgctga ggctgccaac
2821 tccaggcagc agtgggaata ttgaagacat ggaccctgag ctccagcagc tgctggcttg
2881 cggtcttggg acctccgtgg caaggactgg gctggtgatg caggagacag agcagggcct
2941 ggtcgcactg actgcctact ctctgcagcc ccggctaact agcaaggcct ctgagaggag
3001 cagcgtgcag ctgttggcca gctgcataga taaaggagac ctgagtggcc tgcacagtct
3061 gcggtgggag cccccggctg acccgagtcc agtgccagcc agcgaggggg cccagagcct
3121 gcacccaact gagagcatca tccatgttcc cccactggac cccagcatgg ggatggggca
3181 tctgagagcc tcaggggcca ccccttgccc tcctcaggcc attggaaagg cagtccctct
3241 ggctggggaa gctgcagcac cagcccaatt gcaaaacaca gaaaagcagg aagacagtca
3301 ctctggacag aaagggatgg cagtcttggg aaagtcagaa ggagccacga ctacccctcc
3361 ggggcctggg gccccagacc tcctggccgc catgcagagt ctgcggatgg caacagctga
3421 agcccagagc ctgcaccagc aagttctgaa caagcacaag cagggcccca ccccaacagc
3481 cacttccaac cccatccagg acggtcttcg gaaagctggg gctacccaaa gcaacataag
3541 gcctgggggt ggaagtgatc cccggatccc agcagccccc agaaaggtca gtagggaaga
3601 gcaagcacta cccagagggc tgcctggggg gtgggtgaca attcaggatg gcatctacac
3661 cgctcatccc gtgaggacct ttgacccacc tgggggtgtc cagctttctc agagggaacc
3721 ccagtcaagg cacagggaga ctgccctctc agtccaggct ccccgcccac tccagggagg
3781 cccaggtcag agtactgggc cagggcggga ggagcctggg ggctgcacac agatggcctg
3841 ggggccacca gggaaggcga tggcagaagt ctgcccaggg ggcctccaag ctgcagagac
3901 caccctgaag actgcccctc taggccgcca cattctggcc tctgggcccc aagctgcagg
3961 tgccagcccg cacccccata atgcctttgt tcctcctcct cctactctcc cagctgctgt
4021 gacaggacct gactttccag ctggagccca ccgtgctgag gactccatcc agcaagcctc
4081 tgagcccctg aaggaccccc ttcttcactc ccacagcagc cctgctggcc agagaacccc
4141 tggagggtca cagacaaaga ccccaaaact ggaccccacc atgcccccaa agaagaagcc
4201 gcagctgccc cctaaacctg cacacctaac ccagagccac cctcctcaga ggctgcccaa
4261 gcccttgcct ctatctccca gcttttcctc ggaggtgggg caaagagaac accaacgagg
4321 tgagagagat acagccatcc ctcagccagc caaggttccc actactgtag accagggcca
4381 catacctctg gccagatgtc ccagtggaca tagccagccc agcttacaac atggcctcag
4441 caccacggcc cccaggccca ccaagaatca ggctacaggc agcaatgccc agagctctga
4501 gccccccaag ctcaatgccc tcaaccatga tcccacctca ccacagtggg gccccggccc
4561 ctcaggagag cagcccatgg aaggttccca ccaaggggcc cctgagagcc ctgacagtct
4621 gcaaagaaac cagaaagagc tccagggcct cctgaaccag gtgcaagccc tggagaagga
4681 ggccgcaagc agtgtggacg tgcaggccct gcggaggctc tttgaggccg tgccccagct
4741 gggaggggct gctcctcagg ctcctgctgc ccaccaaaag cccgaggcct cagtggagca
4801 ggcctttggg gagctgacac gggtcagcac ggaagttgct caactgaagg aacagacctt
4861 ggcaaggctg ctggacattg aagaggctgt gcacaaggca ctcagctcca tgtctagcct
4921 ccagcctgag gccagtgcca gaggccattt ccagggacct ccaaaagacc acagtgccca
4981 caagatcagt gtcacagtca gcagtagcgc caggcccagt ggctcaggcc aggaggtcgg
5041 aggtcaaact gcagtcaaga accaagccaa ggttgaatgc cacactgagg cccagagtca
5101 agtcaagatc agaaatcaca cagaggccag aggtcacaca gcctcaactg ccccttccac
5161 caggaggcag gagacatcaa gagagtattt gtgccctcct cgggttttac cttccagccg
5221 agattctccc tcctccccaa catttatctc catccagtcg gccacaagga agcctctaga
5281 gactcccagc tttaagggca accctgatgt ctcagtgaaa agcacacaac tggctcagga
5341 cataggccag gccctgctcc accagaaagg tgtccaagac aaaactggga agaaggacat
5401 cacccagtgc tctgtgcaac ctgaacctgc ccctccctca gccagtcccc tgcccagagg
5461 gtggcaaaag agtgttctgg agctacagac ggggccaggg agctcacaac actatggagc
5521 catgagaacc gtgactgaac agtatgagga ggtggaccag tttgggaaca cagtcctcat
5581 gtcttccacc acagtcaccg agcaggcaga gccacccagg aacccaggct cccacctcgg
5641 gctccacgcc tcccccttgc tgaggcagtt cctgcacagc ccagctgggt tcagcagtga
5701 cctgacagaa gctgagacgg tgcaggtgtc ctgcagctac tcccagccag ctgcccagtg
5761 aggcccaccg cctcccacca cacctgccac ctgttcctgg cctccactgc cccaggactg
5821 aagtgggtac ctgcctcctg tacactggag caaggaccaa gaggaaatgg catcttcaga
5881 ggattactgt gggccatttc cctttcgcag ttctttcaat aggcccagtt cttccaaatg
5941 gaaaaagaaa ggtctggaag aggcccacag agttgcacag gcgtgggggt aggatggggg
6001 ctcccagctg cttgtggagg atgtaatata tacagacaca cacatgtttt tcacacaggc
6061 ctggcccacg catcgacatg tgtgaatttg cacaccactg cctgaattgg agccccccag
6121 agtgtccctc tacccagagt ttttatttct ttaattagtc tgagtgttcc cagccatctg
6181 ctccttaatc cctggagagg aacagagcca actggacaca gcgttggtct ctgtttggaa
6241 tcactgtgag gtctccagaa ggacctggcc gccagcccct tcatcaccat ctccatcatt
6301 cagctggtca tctggtggcc caaaggtcac ccaaagagtc agcaatcagc atgtccctag
6361 aagccaaatg cactgccttt ctctgtcccc atgactgtcc cccactctgc accccaaatg
6421 ggaagcatac ggtctgaata aatccaagtt ttattctcta aaaaaaaaaa aaaa
//