LOCUS AJ581669 2060 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for Fc-gamma receptor IIIB (FCGR3B gene).
ACCESSION AJ581669
VERSION AJ581669.1
KEYWORDS Fc-gamma receptor IIIB; FCGR3B gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2060)
AUTHORS Bertrand G.
JOURNAL Submitted (01-SEP-2003) to the INSDC. Bertrand G., R&D Agents
Transmis. par Transfusion, Etablissement francais du Sang P.M., 240
Avenue Emile Jeanbrau, Montpellier cedex 5/34094, FRANCE.
REFERENCE 2
AUTHORS Bertrand G., Duprat E., Lefranc M.P., Marti J., Coste J.
TITLE Characterization of human FCGR3B*02 (HNA-1b, NA2) cDNAs and IMGT
standardized description of FCGR3B alleles
JOURNAL Tissue Antigens 64(2), 119-131(2004).
PUBMED 15245367
FEATURES Location/Qualifiers
source 1..2060
/db_xref="H-InvDB:HIT000249138"
/organism="Homo sapiens"
/chromosome="1"
/map="1q23"
/mol_type="mRNA"
/cell_type="granulocytes"
/tissue_type="peripheral blood"
/db_xref="taxon:9606"
mRNA 1..2051
/gene="FCGR3B"
/allele="HNA1-b"
5'UTR 1..33
exon 1..73
/gene="FCGR3B"
/allele="HNA1-b"
/number=1
CDS 34..735
/gene="FCGR3B"
/allele="HNA1-b"
/product="Fc-gamma receptor IIIB"
/db_xref="GOA:O75015"
/db_xref="H-InvDB:HIT000249138.14"
/db_xref="HGNC:HGNC:3620"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:1E4J"
/db_xref="PDB:1E4K"
/db_xref="PDB:1FNL"
/db_xref="PDB:1T83"
/db_xref="PDB:1T89"
/db_xref="PDB:6EAQ"
/db_xref="UniProtKB/Swiss-Prot:O75015"
/protein_id="CAE46408.1"
/translation="MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVT
LKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQL
EVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIP
KATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLL
FAVDTGLYFSVKTNI"
exon 74..94
/gene="FCGR3B"
/allele="HNA1-b"
/number=2
exon 95..352
/gene="FCGR3B"
/allele="HNA1-b"
/number=3
variation 141
/allele="HNA-1a"
/replace="g"
variation 147
/allele="HNA-1a"
/replace="c"
variation 227
/allele="HNA-1a"
/replace="a"
variation 266
/allele="HNA-1a"
/replace="a"
variation 277
/allele="HNA-1a"
/replace="g"
variation 349
/allele="HNA-1a"
/replace="g"
exon 353..610
/gene="FCGR3B"
/allele="HNA1-b"
/number=4
exon 611..2051
/gene="FCGR3B"
/allele="HNA1-b"
/number=5
3'UTR 736..2051
regulatory 1974..1979
/map="1q23"
/gene="FCGR3B"
/experiment="experimental evidence, no additional details
recorded"
/regulatory_class="polyA_signal_sequence"
regulatory 2035..2040
/map="1q23"
/gene="FCGR3B"
/experiment="experimental evidence, no additional details
recorded"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 622 a 448 c 477 g 513 t
ORIGIN
1 tctttggtga cttgtccact ccagtgtggc atcatgtggc agctgctcct cccaactgct
61 ctgctacttc tagtttcagc tggcatgcgg actgaagatc tcccaaaggc tgtggtgttc
121 ctggagcctc aatggtacag cgtgcttgag aaggacagtg tgactctgaa gtgccaggga
181 gcctactccc ctgaggacaa ttccacacag tggtttcaca atgagagcct catctcaagc
241 caggcctcga gctacttcat tgacgctgcc acagtcaacg acagtggaga gtacaggtgc
301 cagacaaacc tctccaccct cagtgacccg gtgcagctag aagtccatat cggctggctg
361 ttgctccagg cccctcggtg ggtgttcaag gaggaagacc ctattcacct gaggtgtcac
421 agctggaaga acactgctct gcataaggtc acatatttac agaatggcaa agacaggaag
481 tattttcatc ataattctga cttccacatt ccaaaagcca cactcaaaga tagcggctcc
541 tacttctgca gggggcttgt tgggagtaaa aatgtgtctt cagagactgt gaacatcacc
601 atcactcaag gtttggcagt gtcaaccatc tcatcattct ctccacctgg gtaccaagtc
661 tctttctgct tggtgatggt actccttttt gcagtggaca caggactata tttctctgtg
721 aagacaaaca tttgaagctc aacaagagac tggaaggacc ataaacttaa atggagaaag
781 gaccctcaag acaaatgacc cccatcccat gggagtaata agagcagtgg cagcagcatc
841 tctgaacatt tctctggatt tgcaacccca tcatcctcag gcctctctac aagcagcagg
901 aaacatagaa ctcagagcca gatcctttat ccaactctca atttttcctt ggtctccagt
961 ggaagggaaa agcccatgat cttcaagcag ggaagcccca gtgagtagct gcattcctag
1021 aaattgaagt ttcagagcta cacaaacact ttttctgtcc caaccattcc ctcacagtaa
1081 aacaacaata caggctaggg atggtaatcc tttaaacata caaaaattgc tcgtattata
1141 aattacccag tttagagggg aaaaaaagaa aataattatt cctaaacaaa tggataagta
1201 gaattaatgg ttgaggcagg accctacaga gtgtgggaac tgctggggat ctagagaatt
1261 cagtgggacc aatgaaagca tggctgagaa atagcagggt agtccaggat agtctaaggg
1321 aggtgttccc atctgagccc agagataagg gtgtcttcct agaacattag ccgtagtgga
1381 attaacagga aatcatgagg gtgacgtaga attgagtctt ccaggggact ctatcagaac
1441 tggaccattt ccaagtatat aacgatgagc cctctaatgc taggagtagc aaatggtcct
1501 aggaagggga ctgaggattg gggtgggggt ggggtggaaa agaaagtaca gaacaaaccc
1561 tgtgtcactg tcccaagtta agctaagtga acagaactat ctcagcatca gaatgagaaa
1621 gcctgagaag aaagaaccaa ccacaagcac acaggaagga aagcgcagga ggtgaaaatg
1681 ctttcttggc cagggtagta agaattagag gttaatgcag ggactgtaaa accacctttt
1741 ctgcttcaat gtctagttcc tgtatagctt tgttcattgc atttattaaa caaatgttgt
1801 ataaccaata ctaaatgtac tactgagctt cactgagtta cgctgtgaaa ctttcaaatc
1861 cttcttcatg tcagttccaa tgaggtgggg atggagaaga caattgttgc ttatgaaaga
1921 aagctttagc tgtctctgtt ttgtaagctt tcagtgcaac atttcttggt tccaataaag
1981 cattttacaa gatcttgcat gctactctta gatagaagat ggcaaaacca tggtaataaa
2041 atatgaatga taaaaaaaaa
//