LOCUS AJ577574 1474 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens partial mRNA for glycoprotein
endo-alpha-1,2-mannosidase (endo-alpha-1,2-mannosidase gene).
ACCESSION AJ577574
VERSION AJ577574.1
KEYWORDS endo-alpha-1,2-mannosidase gene; glycoprotein
endo-alpha-1,2-mannosidase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1474)
AUTHORS Bause E.
JOURNAL Submitted (18-JUL-2003) to the INSDC. Bause E., Inst. f.
Physiologische Chemie, Universitaet Bonn, Nussallee 11, 53115 Bonn,
GERMANY.
REFERENCE 2
AUTHORS Hardt B., Voelker C., Mundt S., Salska-Navarro M., Hauptmann M.,
Bause E.
TITLE Human endo-alpha1,2-mannosidase is a Golgi-resident type II
membrane protein
JOURNAL Biochimie 87(2), 169-179(2005).
PUBMED 15760709
FEATURES Location/Qualifiers
source 1..1474
/db_xref="H-InvDB:HIT000248907"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 46..>1431
/gene="endo-alpha-1,2-mannosidase"
/product="glycoprotein endo-alpha-1,2-mannosidase"
/function="cleaves Glc1-3Man from N-glycoproteins"
/EC_number="3.2.1.130"
/note="type II membrane protein located in Golgi"
/db_xref="GOA:Q5SRI9"
/db_xref="H-InvDB:HIT000248907.14"
/db_xref="HGNC:HGNC:21072"
/db_xref="InterPro:IPR017853"
/db_xref="InterPro:IPR026071"
/db_xref="UniProtKB/Swiss-Prot:Q5SRI9"
/protein_id="CAE12165.1"
/translation="MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDL
LPELHQRTIHLGKNFDFQKSDRINSETNTKNLKSVEITMKPSKASELNLDELPPLNNY
LHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHNPPDDIGSSFYPELGS
YSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLK
VTFHIEPYSNRDDQNMYKSVKYIIDKYGNHPAFYRYKTKTGNALPMFYVYDSYITKPE
KWANLLTTSGSRSIRNSPYDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSS
HQNWASLKLFCDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQT
RPSLISITSFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKER
ATYALDRQLPVS"
BASE COUNT 480 a 296 c 262 g 436 t
ORIGIN
1 gaccctgcaa aacacttact attttggagt ttaaagtatg tcatcatggc aaagtttcgg
61 agaaggactt gcatcatttt ggcacttttt attctattta ttttctctct gatgatgggt
121 ttaaaaatgc tgagaccaaa tacagctact tttggagctc cttttggact tgaccttctt
181 ccagaacttc atcaacgaac tattcatttg gggaaaaatt ttgatttcca aaagagtgac
241 agaatcaaca gtgaaacaaa taccaagaat ttaaaaagtg ttgaaatcac tatgaaacct
301 tccaaagcct ctgaacttaa cttggatgaa ctaccacctc tgaacaatta tctacatgta
361 ttttattaca gttggtatgg aaatccacaa tttgatggta aatatataca ttggaatcat
421 ccagtgttag agcattggga ccctagaata gccaagaatt atccacaagg gagacacaac
481 cctccagatg acattggctc cagcttttat cctgaattgg gaagttacag ttctcgggat
541 ccttctgtca tagaaactca catgagacaa atgcgctcag cttcaattgg tgtactagcc
601 ctctcttggt acccacctga tgtaaatgat gaaaatggag aacctactga taacttggta
661 cccactattt tggataaagc tcataaatat aacctaaagg ttacttttca catagaacca
721 tatagcaatc gagatgatca aaacatgtac aaaagtgtca agtatattat agacaaatat
781 ggaaatcatc cggcctttta caggtacaag acgaagactg gcaatgctct tcctatgttt
841 tatgtctatg attcctatat taccaagcct gaaaaatggg ccaatctgtt aaccacctca
901 gggtctcgga gtattcgcaa ttctccttat gatggactgt ttattgccct tctggtagaa
961 gaaaaacata agtatgatat tcttcaaagt ggttttgatg gaatttacac atattttgcc
1021 acaaatggct ttacttatgg ctcatcacat cagaattggg ctagcctaaa attattttgt
1081 gataaataca acttaatatt tatcccaagt gtgggcccag gatacataga taccagcatc
1141 cgtccatgga acacgcaaaa cactcggaac cgaatcaatg ggaagtatta tgaaattggt
1201 ctgagtgccg cacttcagac acgccccagc ttaatttcta tcacctcttt taatgagtgg
1261 catgaaggaa ctcagattga aaaagctgtt cccaaaagaa ccagtaatac agtgtaccta
1321 gattaccgtc ctcataaacc aggtctttac ctagaactga ctcgcaagtg gtctgaaaaa
1381 tacagtaagg aaagagcaac ttatgcatta gatcgccagc tgcctgtttc ttaatgcatt
1441 gattaaagtt taatagttat caaaatcacc taat
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