LOCUS AJ548761 4342 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for for peroxisomal lon protease (LONP gene).
ACCESSION AJ548761
VERSION AJ548761.1
KEYWORDS LONP gene; peroxisomal lon protease.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4342)
AUTHORS Van Veldhoven P.P.
JOURNAL Submitted (27-FEB-2003) to the INSDC. Van Veldhoven P.P.,
Farmakologie, K.U.Leuven, Herestraat, B-3000 Leuven, BELGIUM.
REFERENCE 2
AUTHORS De Walque S., Van Veldhoven P.P.
TITLE A mammalian peroxisomal lon protease: cloning and characterization.
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..4342
/db_xref="H-InvDB:HIT000248586"
/organism="Homo sapiens"
/chromosome="16"
/map="16q12"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..2838
/gene="LONP"
/note="short form"
mRNA 1..4342
/gene="LONP"
/note="long form, due to read through of TATA signal"
CDS 90..2648
/gene="LONP"
/product="peroxisomal lon protease"
/function="proteolysis of oxidized proteins "
/db_xref="GOA:Q86WA8"
/db_xref="H-InvDB:HIT000248586.15"
/db_xref="HGNC:HGNC:20598"
/db_xref="InterPro:IPR003111"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR003959"
/db_xref="InterPro:IPR004815"
/db_xref="InterPro:IPR008268"
/db_xref="InterPro:IPR008269"
/db_xref="InterPro:IPR014721"
/db_xref="InterPro:IPR015947"
/db_xref="InterPro:IPR020568"
/db_xref="InterPro:IPR027065"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR027501"
/db_xref="UniProtKB/Swiss-Prot:Q86WA8"
/protein_id="CAD68987.1"
/translation="MSSVSPIQIPSRLPLLLTHEGVLLPGSTMRTSVDSARNLQLVRS
RLLKGTSLQSTILGVIPNTPDPASDAQDLPPLHRIGTAALAVQVVGSNWPKPHYTLLI
TGLCRFQIVQVLKEKPYPIAEVEQLDRLEEFPNTCKMREELGELSEQFYKYAVQLVEM
LDMSVPAVAKLRRLLDSLPREALPDILTSIIRTSNKEKLQILDAVSLEERFKMTIPLL
VRQIEGLKLLQKTRKPKQDDDKRVIAIRPIRRITHISGTLEDEDEDEDNDDIVMLEKK
IRTSSMPEQAHKVCVKEIKRLKKMPQSMPEYALTRNYLELMVELPWNKSTTDRLDIRA
ARILLDNDHYAMEKLKKRVLEYLAVRQLKNNLKGPILCFVGPPGVGKTSVGRSVAKTL
GREFHRIALGGVCDQSDIRGHRRTYVGSMPGRIINGLKTVGVNNPVFLLDEVDKLGKS
LQGDPAAALLEVLDPEQNHNFTDHYLNVAFDLSQVLFIATANTTATIPAALLDRMEII
QVPGYTQEEKIEIAHRHLIPKQLEQHGLTPQQIQIPQVTTLDIITRYTREAGVRSLDR
KLGAICRAVAVKVAEGQHKEAKLDRSDVTEREGCREHILEDEKPESISDTTDLALPPE
MPILIDFHALKDILGPPMYEMEVSQRLSQPGVAIGLAWTPLGGEIMFVEASRMDGEGQ
LTLTGQLGDVMKESAHLAISWLRSNAKKYQLTNAFGSFDLLDNTDIHLHFPAGAVTKD
GPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPVGGIKDKVLAAHRAGLKQV
IIPRRNEKDLEGIPGNVRQDLSFVTASCLDEVLNAAFDGGFTVKTRPGLLNSKL"
regulatory 2774..2779
/gene="LONP"
/regulatory_class="TATA_box"
BASE COUNT 1217 a 993 c 1074 g 1058 t
ORIGIN
1 gggtctgagg tttggtgact gcggggcagg ccgggggcag ctgtctgtct ggctcttttt
61 gacagccccc agtgcgaaag gctgccagca tgtcatcagt gagccccatc cagatcccca
121 gtcgcctccc gctgctgctc acccacgagg gcgtcctgct gcccggctcc accatgcgca
181 ccagcgtgga ctcggcccgc aacctgcagc tggtgcggag ccgccttctg aagggcacgt
241 cgctgcaaag caccatcctg ggcgtcatcc ccaacacgcc tgaccccgcc agcgacgcgc
301 aggacctgcc gccgctgcac aggattggca cagctgcact ggccgttcag gttgtgggca
361 gtaactggcc caagccccac tacactctgt tgattacagg cctatgccgt ttccagattg
421 tacaggtctt aaaagagaag ccatatccca ttgctgaagt ggagcagttg gaccgacttg
481 aggagtttcc caacacctgt aaaatgaggg aggagctagg agaactatca gagcagtttt
541 acaaatatgc agtacaattg gttgaaatgt tggatatgtc tgtccctgca gttgctaaat
601 tgagacgtct tttagatagt cttccaaggg aagctttacc agacatcttg acatcaatta
661 tccgaacaag caacaaagag aaactccaga ttttagatgc tgtgagccta gaggagcggt
721 tcaagatgac tataccactg cttgtcagac aaattgaagg cctgaaattg cttcaaaaaa
781 ccagaaaacc caagcaagat gatgataaga gggttatagc aatacgccct attaggagaa
841 ttacacatat ctcaggtact ttagaagatg aagatgaaga tgaagataat gatgacattg
901 tcatgctaga gaaaaaaata cgaacatcta gtatgccaga gcaggcccat aaagtctgtg
961 tcaaagagat aaagagactc aaaaaaatgc ctcagtcaat gccagaatat gctctgacta
1021 gaaattattt ggaacttatg gtagaacttc cttggaacaa aagtacaact gaccgcctgg
1081 acattagggc agcccggatt cttctggata atgaccatta cgccatggaa aaattgaaga
1141 aaagagtact ggaatacttg gctgtcagac agctcaaaaa taacctgaag ggcccaatcc
1201 tatgctttgt tggccctcct ggagttggta aaacaagtgt gggaagatca gtggccaaga
1261 ctctaggtcg agagttccac aggattgcac ttggaggagt atgtgatcag tctgacattc
1321 gaggacacag gcgcacctat gttggcagca tgcctggtcg catcatcaac ggcttgaaga
1381 ctgtgggagt gaacaaccca gtgttcctat tagatgaggt tgacaaactg ggaaaaagtc
1441 tacagggtga tccagcagca gctctgcttg aggtgttgga tcctgaacaa aaccataact
1501 tcacagatca ttatctaaat gtggcctttg acctttctca agttcttttt atagctactg
1561 ccaacaccac tgctaccatt ccagctgcct tgttggacag aatggagatc attcaggttc
1621 caggttatac acaggaggag aagatagaga ttgcccatag gcacttgatc cccaagcagc
1681 tggaacaaca tgggctgact ccacagcaga ttcagatacc ccaggtcacc actcttgaca
1741 tcatcaccag gtataccaga gaggcagggg ttcgttctct ggatagaaaa cttggggcca
1801 tttgccgagc tgtggccgtg aaggtggcag aaggacagca taaggaagcc aagttggacc
1861 gttctgatgt gactgagaga gaaggttgca gagaacacat cttagaagat gaaaaacctg
1921 aatctatcag tgacactact gacttggctc taccacctga aatgccgatt ttgattgatt
1981 tccatgctct gaaagacatc cttgggcccc cgatgtatga aatggaggta tctcagcgtt
2041 tgagtcagcc aggagtagca ataggtttgg cttggactcc cttaggtgga gaaatcatgt
2101 tcgtggaggc gagtcgaatg gatggcgagg gccagttaac tctgaccggc cagctcgggg
2161 acgtgatgaa ggagtccgcc cacctcgcta tcagctggct ccgcagcaac gcaaagaagt
2221 accagctgac caatgctttt ggaagttttg atcttcttga caacacagac atccatctgc
2281 acttcccagc tggagctgtc acaaaagatg gaccatctgc tggagttacc atagtaacct
2341 gtctcgcctc actttttagt gggcggctgg tacgttcaga tgtagccatg actggagaaa
2401 ttacactgag aggtcttgtt cttccagtgg gtggaattaa agacaaagtg ctggcggcac
2461 acagagcggg actgaagcaa gtcattattc ctcggagaaa tgaaaaagac cttgagggaa
2521 tcccaggcaa cgtacgacag gatttaagtt ttgtcacagc aagctgcctg gatgaggttc
2581 ttaatgcagc ttttgatggt ggctttactg tcaagaccag acctggtctg ttaaatagca
2641 aactgtaggt ccaaatctca attttttaga attttaagtt atgaagtgct caaaggtact
2701 gacacagttg attttattca caccattagg ggtatgcaag atgtccctgt tttataaaca
2761 taatcacaac agtaataaac ctcaagtagt ggctagtgtt tagtatagaa atataagatg
2821 ttgatttagt aaactgataa aaatcgaatt cttgtctttt tagtgggatc cttactgtcc
2881 ctggaaagat atagcatagt ggttctcagc acagtctcca gaacagaagc atctgtagta
2941 cctggtaact tgttagaaat gtacattctc aggctccaca gcaggccgcc tgaatcaaat
3001 cctgggaggt ggggacagaa atctgtgttt taagaagcct tccaggtaat tctgctgcac
3061 actcaagttc aggaaccacc ggtatagacc attaccttag tggatttacc tgtagagttt
3121 attggatcct gaaaccaatc aattacttag aactaggcaa agatgaaagt atagccaact
3181 attcttggct atatatatat attcaagtgg gccgggcgtg atggctcaca cctgtaattc
3241 cagcactttg ggaggtcgag gtaggcagat caccgagccc aagagttcaa gacaatcctg
3301 gccaacggcg aaactctgtc tctacaaaaa atatacaggc gtgttagcat gtgcctgtaa
3361 tcccagcttc ttgggaagct gaggcacaag aattgcctga acccaggagg tggaggttgc
3421 agtgagctgg gatcgcgcca ttgcactcca gcctggctga cagagcgaga ctgtctctaa
3481 aaaaaaaaga ctcaagtgga ccctacaatg aagcctacac atcccaatag aagccccttc
3541 ttatgctgag ggaagcagcc ctcagaacat gatagcttgt atccagcaga gtggcacgtg
3601 ctggcacacc tcacagaagc accctggccc tggatgcctg caacctcaga agagtgcagc
3661 tcccagaggg aggcagccat ccatctggga tggtcctaag catggaatcc taactcctga
3721 ttccgtctcc tatttcttgc ttggctacgc cagttcccaa atctggtaga tgtccatgcc
3781 catgtgctcc tgctgggact caattcaggc tatgtatgac tatgaagtca ggctcatctg
3841 cttactggct gtgtgaactt tttgtatctt ggttttcttc atccatgaaa tccaagtaat
3901 actacctaat tgttactgtg gagattaagt tcaaatgcaa tgtatagtaa tattaagcaa
3961 tttctagtta ttattctagc cagtaatgga cttcagaatc ttttattaca caatataaga
4021 atatgtatgt aaagacattt tggaatttcc tggatgagaa ggaagtctgg gctgggcatg
4081 gtggctcacc cctgtaaccc tagcacttta ggaaatcgag gcgagtggat cacttaagct
4141 caggagttca aggccagcct gggcaacatg gcaaaacccc atttctacaa aaaatacaaa
4201 aattagctgg gcatggtggc acccgcctgt agtccagcta cttgaggctg agatgggagg
4261 atgagggagg tcggggctgc agtgagccaa gatcacgcca ctgcactcca gcaccctggg
4321 cgacagagtg agaccctgtc tc
//