LOCUS AJ536056 4196 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for alpha6-fucosyltransferase (FUT8 gene), splice
variant B6.
ACCESSION AJ536056
VERSION AJ536056.1
KEYWORDS alpha6-fucosyltransferase; FUT8 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4196)
AUTHORS Oriol R.
JOURNAL Submitted (06-JAN-2003) to the INSDC. Oriol R., U504, INSERM, 16
Avenue Paul Vaillant-Couturier, Villejuif, 94807, FRANCE.
REFERENCE 2
AUTHORS Martinez-Duncker I., Michalski J.C., Bauvy C., Candelier J.J.,
Mennesson B., Codogno P., Oriol R., Mollicone R.
TITLE Activity and tissue distribution of splice variants of
alpha6-fucosyltransferase in human embryogenesis
JOURNAL Glycobiology 14(1), 13-25(2004).
PUBMED 14514715
COMMENT related splice variants AJ536053.1, AJ536054.1 and AJ536055.1
FEATURES Location/Qualifiers
source 1..4196
/db_xref="H-InvDB:HIT000248552"
/organism="Homo sapiens"
/chromosome="14"
/map="14q23.2"
/mol_type="mRNA"
/country="France:Paris"
/dev_stage="40-70 days"
/clone="B3CD-L1"
/tissue_type="whole embryo"
/db_xref="taxon:9606"
CDS 1726..3453
/gene="FUT8"
/product="alpha6-fucosyltransferase"
/function="adds fuc in alpha1,6 to the internal GlcNAc of
the core chitobiose"
/EC_number="2.4.1.68"
/db_xref="GOA:Q546E0"
/db_xref="H-InvDB:HIT000248552.14"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR015827"
/db_xref="InterPro:IPR027350"
/db_xref="InterPro:IPR035653"
/db_xref="InterPro:IPR036028"
/db_xref="UniProtKB/TrEMBL:Q546E0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAD59927.1"
/translation="MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELS
KILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKK
QTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHE
RSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGC
GYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGH
WSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKY
LIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQL
LARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGV
ILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQI
AIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVK
YPTYPEAEK"
regulatory 4166..4171
/gene="FUT8"
/regulatory_class="polyA_signal_sequence"
polyA_site 4181
/gene="FUT8"
BASE COUNT 1245 a 854 c 900 g 1197 t
ORIGIN
1 tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa
61 aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat
121 ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt
181 ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt
241 ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt
301 cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat
361 gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa
421 agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt
481 ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac
541 agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg
601 aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg
661 tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc
721 ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa
781 taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa
841 gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac
901 ataagagggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca
961 ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg
1021 ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag
1081 aaatggttct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc ccaggcttgg
1141 gatctgggtc ccaaggctac agggaagagt ttggaacggg aagctcatct tccggccctc
1201 tgattggccg gctcgcactc cactcaccgg cgcgcagctc tgattggcct cggcggcacc
1261 cctcgtcccg cgactacttt gtgtgctggg gcggcgcgct ccggtcctcc cgctcagctg
1321 gcggtctggg ctgctctggg gcagcccttc ggtccactgc tctgcatcgc gggcgccggg
1381 aattttccga gtccgagcgg gttgctgctt ttgctcagag gacatccatg accctaatgg
1441 tctttttgtt caagataaag tgattttttg cctttgttga ttaactggac aaattcagca
1501 tgtagagcgc atgaagtaca ggacaataaa gcttcctaca catatcacca ggaggatctc
1561 tttgaaagat tcactgcagg actaccagag agaataattt gtctgaagca tcatgtgttg
1621 aaacaacaga agtctattca cctgtgcact aactagaaac agagttacaa tgttttcaat
1681 tctttgagct ccaggactcc agggaagtga gttgaaaatc tgaaaatgcg gccatggact
1741 ggttcctggc gttggattat gctcattctt tttgcctggg ggaccttgct gttttatata
1801 ggtggtcact tggtacgaga taatgaccat cctgatcact ctagccgaga actgtccaag
1861 attctggcaa agcttgaacg cttaaaacag cagaatgaag acttgaggcg aatggccgaa
1921 tctctccgga taccagaagg ccctattgat caggggccag ctataggaag agtacgcgtt
1981 ttagaagagc agcttgttaa ggccaaagaa cagattgaaa attacaagaa acagaccaga
2041 aatggtctgg ggaaggatca tgaaatcctg aggaggagga ttgaaaatgg agctaaagag
2101 ctctggtttt tcctacagag tgaattgaag aaattaaaga acttagaagg aaatgaactc
2161 caaagacatg cagatgaatt tcttttggat ttaggacatc atgaaaggtc tataatgacg
2221 gatctatact acctcagtca gacagatgga gcaggtgatt ggcgggaaaa agaggccaaa
2281 gatctgacag aactggttca gcggagaata acatatcttc agaatcccaa ggactgcagc
2341 aaagccaaaa agctggtgtg taatatcaac aaaggctgtg gctatggctg tcagctccat
2401 catgtggtct actgcttcat gattgcatat ggcacccagc gaacactcat cttggaatct
2461 cagaattggc gctatgctac tggtggatgg gagactgtat ttaggcctgt aagtgagaca
2521 tgcacagaca gatctggcat ctccactgga cactggtcag gtgaagtgaa ggacaaaaat
2581 gttcaagtgg tcgagcttcc cattgtagac agtcttcatc cccgtcctcc atatttaccc
2641 ttggctgtac cagaagacct cgcagatcga cttgtacgag tgcatggtga ccctgcagtg
2701 tggtgggtgt ctcagtttgt caaatacttg atccgcccac agccttggct agaaaaagaa
2761 atagaagaag ccaccaagaa gcttggcttc aaacatccag ttattggagt ccatgtcaga
2821 cgcacagaca aagtgggaac agaagctgcc ttccatccca ttgaagagta catggtgcat
2881 gttgaagaac attttcagct tcttgcacgc agaatgcaag tggacaaaaa aagagtgtat
2941 ttggccacag atgacccttc tttattaaag gaggcaaaaa caaagtaccc caattatgaa
3001 tttattagtg ataactctat ttcctggtca gctggactgc acaatcgata cacagaaaat
3061 tcacttcgtg gagtgatcct ggatatacat tttctctctc aggcagactt cctagtgtgt
3121 actttttcat cccaggtctg tcgagttgct tatgaaatta tgcaaacact acatcctgat
3181 gcctctgcaa acttccattc tttagatgac atctactatt ttgggggcca gaatgcccac
3241 aatcaaattg ccatttatgc tcaccaaccc cgaactgcag atgaaattcc catggaacct
3301 ggagatatca ttggtgtggc tggaaatcat tgggatggct attctaaagg tgtcaacagg
3361 aaattgggaa ggacgggcct atatccctcc tacaaagttc gagagaagat agaaacggtc
3421 aagtacccca catatcctga ggctgagaaa taaagctcag atggaagaga taaacgacca
3481 aactcagttc gaccaaactc agttcaaacc atttgagcca aactgtagat gaagagggct
3541 ctgatctaac aaaataaggt tatatgagta gatactctca gcaccaagag cagctgggaa
3601 ctgacatagg cttcaattgg tggaattcct ctttaacaag ggctgcaatg cctcataccc
3661 atgcacagta caataatgta ctcacatata acatgcaaac aggttgtttt ctactttgcc
3721 cctttcagta tgtccccata agacaaacac tgccatattg tgtaatttaa gtgacacaga
3781 cattttgtgt gagacttaaa acatggtgcc tatatctgag agacctgtgt gaactattga
3841 gaagatcgga acagctcctt actctgagga agttgattct tatttgatgg tggtattgtg
3901 accactgaat tcactccagt caacagattc agaatgagaa tggacgtttg gttttttttt
3961 gtttttgttt ttgttttttc ctttataagg ttgtctgttt tttttttttt aaataattgc
4021 atcagttcat tgacctcatc attaataagt gaagaataca tcagaaaata aaatattcac
4081 tctccattag aaaattttgt aaaacaatgc catgaacaaa ttctttagta ctcaatgttt
4141 ctggacattc tctttgataa caaaaaataa attttaaaaa aaaaaaaaaa aaaaaa
//