LOCUS AJ536055 3568 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for alpha6-fucosyltransferase (FUT8 gene), splice
variant B5.
ACCESSION AJ536055
VERSION AJ536055.1
KEYWORDS alpha6-fucosyltransferase; FUT8 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3568)
AUTHORS Oriol R.
JOURNAL Submitted (06-JAN-2003) to the INSDC. Oriol R., U504, INSERM, 16
Avenue Paul Vaillant-Couturier, Villejuif, 94807, FRANCE.
REFERENCE 2
AUTHORS Martinez-Duncker I., Michalski J.C., Bauvy C., Candelier J.J.,
Mennesson B., Codogno P., Oriol R., Mollicone R.
TITLE Activity and tissue distribution of splice variants of
alpha6-fucosyltransferase in human embryogenesis
JOURNAL Glycobiology 14(1), 13-25(2004).
PUBMED 14514715
COMMENT related splice variants AJ536053.1, AJ536054.1 and AJ536056.1
FEATURES Location/Qualifiers
source 1..3568
/db_xref="H-InvDB:HIT000248551"
/organism="Homo sapiens"
/chromosome="14"
/map="14q23.2"
/mol_type="mRNA"
/country="France:Paris"
/dev_stage="40-70 days"
/clone="B2D-L1"
/tissue_type="whole embryo"
/db_xref="taxon:9606"
CDS 1098..2825
/gene="FUT8"
/product="alpha6-fucosyltransferase"
/function="adds fuc in alpha1,6 to the internal GlcNAc of
the core chitobiose"
/EC_number="2.4.1.68"
/db_xref="GOA:Q546E0"
/db_xref="H-InvDB:HIT000248551.13"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR015827"
/db_xref="InterPro:IPR027350"
/db_xref="InterPro:IPR035653"
/db_xref="InterPro:IPR036028"
/db_xref="UniProtKB/TrEMBL:Q546E0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAD59926.1"
/translation="MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELS
KILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKK
QTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHE
RSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGC
GYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGH
WSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKY
LIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQL
LARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGV
ILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQI
AIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVK
YPTYPEAEK"
regulatory 3538..3543
/gene="FUT8"
/regulatory_class="polyA_signal_sequence"
polyA_site 3553
/gene="FUT8"
BASE COUNT 1054 a 751 c 788 g 975 t
ORIGIN
1 cgtttagtac agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat
61 tattttattg aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac
121 atcttctgtg tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag
181 ggagataatc ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa
241 gagctgacaa taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc
301 ttgaggacaa gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag
361 ttcctggtac ataagagggt ctcaataaat atgtgaattt atgaatatta ggcagattgc
421 aaccttgaca ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc
481 taaaaggccg ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc
541 aagcctagag aaatggttct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc
601 ccaggcttgg gatctgggtc ccaaggctac agggaagagt ttggaacggg aagctcatct
661 tccggccctc tgattggccg gctcgcactc cactcaccgg cgcgcagctc tgattggcct
721 cggcggcacc cctcgtcccg cgactacttt gtgtgctggg gcggcgcgct ccggtcctcc
781 cgctcagctg gcggtctggg ctgctctggg gcagcccttc ggtccactgc tctgcatcgc
841 gggcgccggg aattttccga gtccgagcgg catgtagagc gcatgaagta caggacaata
901 aagcttccta cacatatcac caggaggatc tctttgaaag attcactgca ggactaccag
961 agagaataat ttgtctgaag catcatgtgt tgaaacaaca gaagtctatt cacctgtgca
1021 ctaactagaa acagagttac aatgttttca attctttgag ctccaggact ccagggaagt
1081 gagttgaaaa tctgaaaatg cggccatgga ctggttcctg gcgttggatt atgctcattc
1141 tttttgcctg ggggaccttg ctgttttata taggtggtca cttggtacga gataatgacc
1201 atcctgatca ctctagccga gaactgtcca agattctggc aaagcttgaa cgcttaaaac
1261 agcagaatga agacttgagg cgaatggccg aatctctccg gataccagaa ggccctattg
1321 atcaggggcc agctatagga agagtacgcg ttttagaaga gcagcttgtt aaggccaaag
1381 aacagattga aaattacaag aaacagacca gaaatggtct ggggaaggat catgaaatcc
1441 tgaggaggag gattgaaaat ggagctaaag agctctggtt tttcctacag agtgaattga
1501 agaaattaaa gaacttagaa ggaaatgaac tccaaagaca tgcagatgaa tttcttttgg
1561 atttaggaca tcatgaaagg tctataatga cggatctata ctacctcagt cagacagatg
1621 gagcaggtga ttggcgggaa aaagaggcca aagatctgac agaactggtt cagcggagaa
1681 taacatatct tcagaatccc aaggactgca gcaaagccaa aaagctggtg tgtaatatca
1741 acaaaggctg tggctatggc tgtcagctcc atcatgtggt ctactgcttc atgattgcat
1801 atggcaccca gcgaacactc atcttggaat ctcagaattg gcgctatgct actggtggat
1861 gggagactgt atttaggcct gtaagtgaga catgcacaga cagatctggc atctccactg
1921 gacactggtc aggtgaagtg aaggacaaaa atgttcaagt ggtcgagctt cccattgtag
1981 acagtcttca tccccgtcct ccatatttac ccttggctgt accagaagac ctcgcagatc
2041 gacttgtacg agtgcatggt gaccctgcag tgtggtgggt gtctcagttt gtcaaatact
2101 tgatccgccc acagccttgg ctagaaaaag aaatagaaga agccaccaag aagcttggct
2161 tcaaacatcc agttattgga gtccatgtca gacgcacaga caaagtggga acagaagctg
2221 ccttccatcc cattgaagag tacatggtgc atgttgaaga acattttcag cttcttgcac
2281 gcagaatgca agtggacaaa aaaagagtgt atttggccac agatgaccct tctttattaa
2341 aggaggcaaa aacaaagtac cccaattatg aatttattag tgataactct atttcctggt
2401 cagctggact gcacaatcga tacacagaaa attcacttcg tggagtgatc ctggatatac
2461 attttctctc tcaggcagac ttcctagtgt gtactttttc atcccaggtc tgtcgagttg
2521 cttatgaaat tatgcaaaca ctacatcctg atgcctctgc aaacttccat tctttagatg
2581 acatctacta ttttgggggc cagaatgccc acaatcaaat tgccatttat gctcaccaac
2641 cccgaactgc agatgaaatt cccatggaac ctggagatat cattggtgtg gctggaaatc
2701 attgggatgg ctattctaaa ggtgtcaaca ggaaattggg aaggacgggc ctatatccct
2761 cctacaaagt tcgagagaag atagaaacgg tcaagtaccc cacatatcct gaggctgaga
2821 aataaagctc agatggaaga gataaacgac caaactcagt tcgaccaaac tcagttcaaa
2881 ccatttgagc caaactgtag atgaagaggg ctctgatcta acaaaataag gttatatgag
2941 tagatactct cagcaccaag agcagctggg aactgacata ggcttcaatt ggtggaattc
3001 ctctttaaca agggctgcaa tgcctcatac ccatgcacag tacaataatg tactcacata
3061 taacatgcaa acaggttgtt ttctactttg cccctttcag tatgtcccca taagacaaac
3121 actgccatat tgtgtaattt aagtgacaca gacattttgt gtgagactta aaacatggtg
3181 cctatatctg agagacctgt gtgaactatt gagaagatcg gaacagctcc ttactctgag
3241 gaagttgatt cttatttgat ggtggtattg tgaccactga attcactcca gtcaacagat
3301 tcagaatgag aatggacgtt tggttttttt ttgtttttgt ttttgttttt tcctttataa
3361 ggttgtctgt tttttttttt ttaaataatt gcatcagttc attgacctca tcattaataa
3421 gtgaagaata catcagaaaa taaaatattc actctccatt agaaaatttt gtaaaacaat
3481 gccatgaaca aattctttag tactcaatgt ttctggacat tctctttgat aacaaaaaat
3541 aaattttaaa aaaaaaaaaa aaaaaaaa
//