LOCUS AJ536053 3666 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for alpha6-fucosyltransferase (FUT8 gene), splice
variant B3.
ACCESSION AJ536053
VERSION AJ536053.1
KEYWORDS alpha6-fucosyltransferase; FUT8 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3666)
AUTHORS Oriol R.
JOURNAL Submitted (06-JAN-2003) to the INSDC. Oriol R., U504, INSERM, 16
Avenue Paul Vaillant-Couturier, Villejuif, 94807, FRANCE.
REFERENCE 2
AUTHORS Martinez-Duncker I., Michalski J.C., Bauvy C., Candelier J.J.,
Mennesson B., Codogno P., Oriol R., Mollicone R.
TITLE Activity and tissue distribution of splice variants of
alpha6-fucosyltransferase in human embryogenesis
JOURNAL Glycobiology 14(1), 13-25(2004).
PUBMED 14514715
COMMENT related splice variants AJ536054.1, AJ536055.1 and AJ536056.1
FEATURES Location/Qualifiers
source 1..3666
/db_xref="H-InvDB:HIT000248549"
/organism="Homo sapiens"
/chromosome="14"
/map="14q23.2"
/mol_type="mRNA"
/country="France:Paris"
/dev_stage="40-70 days"
/clone="B2CD-L1"
/tissue_type="whole embryo"
/db_xref="taxon:9606"
CDS 1196..2923
/gene="FUT8"
/product="alpha6-fucosyltransferase"
/function="adds fuc in alpha1,6 to the internal GlcNAc of
the core chitobiose"
/EC_number="2.4.1.68"
/db_xref="GOA:Q546E0"
/db_xref="H-InvDB:HIT000248549.13"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR015827"
/db_xref="InterPro:IPR027350"
/db_xref="InterPro:IPR035653"
/db_xref="InterPro:IPR036028"
/db_xref="UniProtKB/TrEMBL:Q546E0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAD59924.1"
/translation="MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELS
KILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKK
QTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHE
RSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGC
GYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGH
WSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKY
LIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQL
LARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGV
ILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQI
AIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVK
YPTYPEAEK"
regulatory 3636..3641
/gene="FUT8"
/regulatory_class="polyA_signal_sequence"
polyA_site 3651
/gene="FUT8"
BASE COUNT 1077 a 768 c 808 g 1013 t
ORIGIN
1 cgtttagtac agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat
61 tattttattg aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac
121 atcttctgtg tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag
181 ggagataatc ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa
241 gagctgacaa taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc
301 ttgaggacaa gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag
361 ttcctggtac ataagagggt ctcaataaat atgtgaattt atgaatatta ggcagattgc
421 aaccttgaca ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc
481 taaaaggccg ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc
541 aagcctagag aaatggttct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc
601 ccaggcttgg gatctgggtc ccaaggctac agggaagagt ttggaacggg aagctcatct
661 tccggccctc tgattggccg gctcgcactc cactcaccgg cgcgcagctc tgattggcct
721 cggcggcacc cctcgtcccg cgactacttt gtgtgctggg gcggcgcgct ccggtcctcc
781 cgctcagctg gcggtctggg ctgctctggg gcagcccttc ggtccactgc tctgcatcgc
841 gggcgccggg aattttccga gtccgagcgg gttgctgctt ttgctcagag gacatccatg
901 accctaatgg tctttttgtt caagataaag tgattttttg cctttgttga ttaactggac
961 aaattcagca tgtagagcgc atgaagtaca ggacaataaa gcttcctaca catatcacca
1021 ggaggatctc tttgaaagat tcactgcagg actaccagag agaataattt gtctgaagca
1081 tcatgtgttg aaacaacaga agtctattca cctgtgcact aactagaaac agagttacaa
1141 tgttttcaat tctttgagct ccaggactcc agggaagtga gttgaaaatc tgaaaatgcg
1201 gccatggact ggttcctggc gttggattat gctcattctt tttgcctggg ggaccttgct
1261 gttttatata ggtggtcact tggtacgaga taatgaccat cctgatcact ctagccgaga
1321 actgtccaag attctggcaa agcttgaacg cttaaaacag cagaatgaag acttgaggcg
1381 aatggccgaa tctctccgga taccagaagg ccctattgat caggggccag ctataggaag
1441 agtacgcgtt ttagaagagc agcttgttaa ggccaaagaa cagattgaaa attacaagaa
1501 acagaccaga aatggtctgg ggaaggatca tgaaatcctg aggaggagga ttgaaaatgg
1561 agctaaagag ctctggtttt tcctacagag tgaattgaag aaattaaaga acttagaagg
1621 aaatgaactc caaagacatg cagatgaatt tcttttggat ttaggacatc atgaaaggtc
1681 tataatgacg gatctatact acctcagtca gacagatgga gcaggtgatt ggcgggaaaa
1741 agaggccaaa gatctgacag aactggttca gcggagaata acatatcttc agaatcccaa
1801 ggactgcagc aaagccaaaa agctggtgtg taatatcaac aaaggctgtg gctatggctg
1861 tcagctccat catgtggtct actgcttcat gattgcatat ggcacccagc gaacactcat
1921 cttggaatct cagaattggc gctatgctac tggtggatgg gagactgtat ttaggcctgt
1981 aagtgagaca tgcacagaca gatctggcat ctccactgga cactggtcag gtgaagtgaa
2041 ggacaaaaat gttcaagtgg tcgagcttcc cattgtagac agtcttcatc cccgtcctcc
2101 atatttaccc ttggctgtac cagaagacct cgcagatcga cttgtacgag tgcatggtga
2161 ccctgcagtg tggtgggtgt ctcagtttgt caaatacttg atccgcccac agccttggct
2221 agaaaaagaa atagaagaag ccaccaagaa gcttggcttc aaacatccag ttattggagt
2281 ccatgtcaga cgcacagaca aagtgggaac agaagctgcc ttccatccca ttgaagagta
2341 catggtgcat gttgaagaac attttcagct tcttgcacgc agaatgcaag tggacaaaaa
2401 aagagtgtat ttggccacag atgacccttc tttattaaag gaggcaaaaa caaagtaccc
2461 caattatgaa tttattagtg ataactctat ttcctggtca gctggactgc acaatcgata
2521 cacagaaaat tcacttcgtg gagtgatcct ggatatacat tttctctctc aggcagactt
2581 cctagtgtgt actttttcat cccaggtctg tcgagttgct tatgaaatta tgcaaacact
2641 acatcctgat gcctctgcaa acttccattc tttagatgac atctactatt ttgggggcca
2701 gaatgcccac aatcaaattg ccatttatgc tcaccaaccc cgaactgcag atgaaattcc
2761 catggaacct ggagatatca ttggtgtggc tggaaatcat tgggatggct attctaaagg
2821 tgtcaacagg aaattgggaa ggacgggcct atatccctcc tacaaagttc gagagaagat
2881 agaaacggtc aagtacccca catatcctga ggctgagaaa taaagctcag atggaagaga
2941 taaacgacca aactcagttc gaccaaactc agttcaaacc atttgagcca aactgtagat
3001 gaagagggct ctgatctaac aaaataaggt tatatgagta gatactctca gcaccaagag
3061 cagctgggaa ctgacatagg cttcaattgg tggaattcct ctttaacaag ggctgcaatg
3121 cctcataccc atgcacagta caataatgta ctcacatata acatgcaaac aggttgtttt
3181 ctactttgcc cctttcagta tgtccccata agacaaacac tgccatattg tgtaatttaa
3241 gtgacacaga cattttgtgt gagacttaaa acatggtgcc tatatctgag agacctgtgt
3301 gaactattga gaagatcgga acagctcctt actctgagga agttgattct tatttgatgg
3361 tggtattgtg accactgaat tcactccagt caacagattc agaatgagaa tggacgtttg
3421 gttttttttt gtttttgttt ttgttttttc ctttataagg ttgtctgttt tttttttttt
3481 aaataattgc atcagttcat tgacctcatc attaataagt gaagaataca tcagaaaata
3541 aaatattcac tctccattag aaaattttgt aaaacaatgc catgaacaaa ttctttagta
3601 ctcaatgttt ctggacattc tctttgataa caaaaaataa attttaaaaa aaaaaaaaaa
3661 aaaaaa
//